A Weng

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Saponins modulate the intracellular trafficking of protein toxins
    Alexander Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin Berlin, Germany
    J Control Release 164:74-86. 2012
  2. doi request reprint The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins
    Alexander Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Mol Oncol 6:323-32. 2012
  3. ncbi request reprint Liquid-chromatographic profiling of Saponinum album (Merck)
    A Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin, Berlin, Germany
    Pharmazie 66:744-6. 2011
  4. pmc The distribution of saponins in vivo affects their synergy with chimeric toxins against tumours expressing human epidermal growth factor receptors in mice
    C Bachran
    Zentralinstitut für Laboratoriumsmedizin und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Br J Pharmacol 159:345-52. 2010
  5. doi request reprint Enhancement of saporin toxicity against U937 cells by Gypsophila saponins
    A Weng
    Institute of Pharmacy, Free University Berlin, Berlin, Germany
    J Immunotoxicol 5:287-92. 2008
  6. ncbi request reprint Saponins as tool for improved targeted tumor therapies
    H Fuchs
    Zentralinstitut für Laboratoriumsmedizin und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany
    Curr Drug Targets 10:140-51. 2009

Collaborators

Detail Information

Publications6

  1. doi request reprint Saponins modulate the intracellular trafficking of protein toxins
    Alexander Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin Berlin, Germany
    J Control Release 164:74-86. 2012
    ..The applicability of the saponin-mediated effect was demonstrated in vivo in a syngeneic tumor model using a saporin-based targeted anti-tumor toxin in combination with characterized saponins...
  2. doi request reprint The toxin component of targeted anti-tumor toxins determines their efficacy increase by saponins
    Alexander Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Mol Oncol 6:323-32. 2012
    ..Surface plasmon resonance measurements point to a transient binding of SA1641 to the toxin components of targeted toxins...
  3. ncbi request reprint Liquid-chromatographic profiling of Saponinum album (Merck)
    A Weng
    Institut für Laboratoriumsmedizin, Klinische Chemie und Pathobiochemie, Charite Universitatsmedizin, Berlin, Germany
    Pharmazie 66:744-6. 2011
    ..Based on these results it was concluded that the cytotoxicity enhancer effect of Saponinum album (Merck) is not attributable to a single, activity determining saponin...
  4. pmc The distribution of saponins in vivo affects their synergy with chimeric toxins against tumours expressing human epidermal growth factor receptors in mice
    C Bachran
    Zentralinstitut für Laboratoriumsmedizin und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Br J Pharmacol 159:345-52. 2010
    ..Here, we describe the distribution of Saponinum album (Spn) from Gypsophila paniculata L. in mice after subcutaneous injection...
  5. doi request reprint Enhancement of saporin toxicity against U937 cells by Gypsophila saponins
    A Weng
    Institute of Pharmacy, Free University Berlin, Berlin, Germany
    J Immunotoxicol 5:287-92. 2008
    ..The results here indicate that the Gypsophila saponins induce, in some manner yet to be fully defined, a stimulation of the endocytosis of saporin by these cells...
  6. ncbi request reprint Saponins as tool for improved targeted tumor therapies
    H Fuchs
    Zentralinstitut für Laboratoriumsmedizin und Pathobiochemie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany
    Curr Drug Targets 10:140-51. 2009
    ....