Stefan G Tullius

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Contribution of prolonged ischemia and donor age to chronic renal allograft dysfunction
    S G Tullius
    Department of Surgery, Charite Virchow Clinic, Berlin, Germany
    J Am Soc Nephrol 11:1317-24. 2000
  2. ncbi request reprint The marginal kidney donor
    Stefan G Tullius
    Department of Surgery, Charite Campus Virchow Clinic, Berlin, Germany
    Curr Opin Urol 12:101-7. 2002
  3. ncbi request reprint Accumulation of crystal deposits in abdominal organs following perfusion with defrosted University of Wisconsin solutions
    Stefan G Tullius
    Department of Surgery, Charite Virchow Clinic, Berlin, Germany
    Am J Transplant 2:627-30. 2002
  4. ncbi request reprint Early cellular markers for the prediction of chronic graft deterioration in a retransplantation model
    S G Tullius
    Department of General and Transplantation Surgery, Charite, Virchow Clinic, Berlin, Germany
    Transplant Proc 34:2357-8. 2002
  5. ncbi request reprint Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1
    Stefan G Tullius
    Department of General and Transplantation Surgery, Charite Campus Virchow Clinic, D 13353 Berlin, Germany
    Transplantation 74:591-8. 2002
  6. doi request reprint Cold ischemia does not interfere with tolerance induction
    Anja Reutzel-Selke
    Department of Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Germany
    Transplantation 87:1116-24. 2009
  7. doi request reprint Potent early immune response after kidney transplantation in patients of the European senior transplant program
    Johann Pratschke
    Department of General, Visceral, and Transplantation Surgery, Charite Virchow Clinic, Universitatsmedizin Berlin, Germany
    Transplantation 87:992-1000. 2009
  8. ncbi request reprint The impact of immune-activating processes following transplantation on chronic allograft nephropathy
    Christoph Heidenhain
    Department of General and Transplantation Surgery Charité Campus Virchow Clinic, Berlin, Germany
    Kidney Int 64:1125-33. 2003
  9. doi request reprint Ischemic preconditioning produces systemic protective and adoptively transferable effects
    Anja Reutzel-Selke
    Department of General, Visceral, and Transplant Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Berlin, Germany
    Kidney Int 74:622-30. 2008
  10. ncbi request reprint Short-term immunosuppressive treatment of the donor ameliorates consequences of ischemia/ reperfusion injury and long-term graft function in renal allografts from older donors
    Anja Reutzel-Selke
    Department of General and Transplantation Surgery, Charite Campus Virchow Clinic, Berlin, Germany
    Transplantation 75:1786-92. 2003

Detail Information

Publications38

  1. ncbi request reprint Contribution of prolonged ischemia and donor age to chronic renal allograft dysfunction
    S G Tullius
    Department of Surgery, Charite Virchow Clinic, Berlin, Germany
    J Am Soc Nephrol 11:1317-24. 2000
    ..Donor age and duration of ischemia act in a synergistic manner in our model. Brief ischemic times seem of particular relevance when grafts from older donors are being used...
  2. ncbi request reprint The marginal kidney donor
    Stefan G Tullius
    Department of Surgery, Charite Campus Virchow Clinic, Berlin, Germany
    Curr Opin Urol 12:101-7. 2002
    ..The present review analyzes potential risk factors, suggests scoring systems for a more precise definition, and discusses potential treatment options to improve the quality of marginal grafts...
  3. ncbi request reprint Accumulation of crystal deposits in abdominal organs following perfusion with defrosted University of Wisconsin solutions
    Stefan G Tullius
    Department of Surgery, Charite Virchow Clinic, Berlin, Germany
    Am J Transplant 2:627-30. 2002
    ..UW solutions can reach subzero temperatures under commonly used transportation conditions. Under these conditions, visible crystals accumulate and can be detected in abdominal organs of an experimental system...
  4. ncbi request reprint Early cellular markers for the prediction of chronic graft deterioration in a retransplantation model
    S G Tullius
    Department of General and Transplantation Surgery, Charite, Virchow Clinic, Berlin, Germany
    Transplant Proc 34:2357-8. 2002
  5. ncbi request reprint Inhibition of ischemia/reperfusion injury and chronic graft deterioration by a single-donor treatment with cobalt-protoporphyrin for the induction of heme oxygenase-1
    Stefan G Tullius
    Department of General and Transplantation Surgery, Charite Campus Virchow Clinic, D 13353 Berlin, Germany
    Transplantation 74:591-8. 2002
    ....
  6. doi request reprint Cold ischemia does not interfere with tolerance induction
    Anja Reutzel-Selke
    Department of Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Germany
    Transplantation 87:1116-24. 2009
    ..Ischemia/reperfusion injury activates innate immunity, which in turn may prevent tolerance induction. We asked whether prolonged cold ischemia interferes with successful tolerance induction...
  7. doi request reprint Potent early immune response after kidney transplantation in patients of the European senior transplant program
    Johann Pratschke
    Department of General, Visceral, and Transplantation Surgery, Charite Virchow Clinic, Universitatsmedizin Berlin, Germany
    Transplantation 87:992-1000. 2009
    ..Age-adapted immunosuppressive protocols considering these changes are currently not established. This study analyzed the age-dependent immune response after human kidney transplantation...
  8. ncbi request reprint The impact of immune-activating processes following transplantation on chronic allograft nephropathy
    Christoph Heidenhain
    Department of General and Transplantation Surgery Charité Campus Virchow Clinic, Berlin, Germany
    Kidney Int 64:1125-33. 2003
    ..However, only very little information is presently available on the influence of systemic immune-activating processes following organ engraftment...
  9. doi request reprint Ischemic preconditioning produces systemic protective and adoptively transferable effects
    Anja Reutzel-Selke
    Department of General, Visceral, and Transplant Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Berlin, Germany
    Kidney Int 74:622-30. 2008
    ..These results show that renal ischemic preconditioning is associated with time-dependent local and systemically transferable protection...
  10. ncbi request reprint Short-term immunosuppressive treatment of the donor ameliorates consequences of ischemia/ reperfusion injury and long-term graft function in renal allografts from older donors
    Anja Reutzel-Selke
    Department of General and Transplantation Surgery, Charite Campus Virchow Clinic, Berlin, Germany
    Transplantation 75:1786-92. 2003
    ..Here we tested the impact of short-term donor treatment with established immunosuppressants...
  11. doi request reprint Influence of donor- and recipient-specific factors on the postoperative course after combined pancreas-kidney transplantation
    Peter Thomas Fellmer
    Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Berlin, Germany
    Langenbecks Arch Surg 395:19-25. 2010
    ..Pancreas transplantation is associated with postoperative complications. We defined and identified donor- and recipient-specific factors related to postoperative complications...
  12. ncbi request reprint Alterations of the immune response with increasing recipient age are associated with reduced long-term organ graft function of rat kidney allografts
    Andreas Pascher
    Department of General Surgery, Charite Campus Virchow, Berlin, Germany
    Transplantation 76:1560-8. 2003
    ..Clinically, an increasing number of older recipients are listed for transplantation. We examined recipient age-associated alterations of the immune response and their effects on graft function...
  13. ncbi request reprint Donor hypertension increases graft immunogenicity and intensifies chronic changes in long-surviving renal allografts
    Johann Pratschke
    Department of Surgery, Humboldt University, Charite Virchow Clinic, Berlin, Germany Johann
    Transplantation 77:43-8. 2004
    ..To define the influences of donor hypertension, we compared the behavior of kidney allografts from hypertensive and normotensive donors in an established rat model of chronic rejection...
  14. doi request reprint Symptomatic lymphoceles after kidney transplantation - multivariate analysis of risk factors and outcome after laparoscopic fenestration
    Frank Ulrich
    Department of General, Visceral and Transplantation Surgery, Charite Universitatsmedizin Berlin, Campus Virchow Clinical Centre, Berlin, Germany
    Clin Transplant 24:273-80. 2010
    ..We conclude that diabetes is an independent risk factor for lymphocele development, and laparoscopic fenestration should be the treatment of choice for larger and symptomatic lymphoceles, as it is safe and offers a low recurrence rate...
  15. doi request reprint Novel markers in zero-hour kidney biopsies indicate graft quality and clinical outcome
    Katja Kotsch
    Institute of Medical Immunology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Transplantation 90:958-65. 2010
    ..To uncover novel candidate markers characteristic of subtle inflammation and immune activation present during the intraoperative period, we investigated messenger RNA (mRNA) gene expression profiles in renal zero biopsies...
  16. doi request reprint Donor brain death significantly interferes with tolerance induction protocols
    Maja Francuski
    Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Clinic, Universitatsmedizin Berlin, Germany
    Transpl Int 22:482-93. 2009
    ..RIB 5/2 treatment significantly improved graft function in recipients of living donor grafts; however, it was not effective in recipients of brain-dead donor organs...
  17. ncbi request reprint Heme oxygenase-1 ameliorates ischemia/reperfusion injury by targeting dendritic cell maturation and migration
    Katja Kotsch
    Institute of Medical Immunology, Universitätsmedizin Charité Campus Mitte, Berlin, Germany
    Antioxid Redox Signal 9:2049-63. 2007
    ..This observation suggests that HO-1/CO induction protects marginal allografts by inhibiting the immunogenicity of donor-derived dendritic cells...
  18. ncbi request reprint Age and immune response in organ transplantation
    Paulo N A Martins
    Department of General and Transplantation Surgery, Charite Virchow Clinic, Humboldt University, Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Transplantation 79:127-32. 2005
    ..Here, we are going to review the immunologic changes associated with the aging process relevant for transplantation and their impact on immunosuppressive protocols, organ allocation policies, and transplantation outcome...
  19. ncbi request reprint Modifications of immune regulations with increasing donor & recipient age
    Andreas Pascher
    Department of General Surgery, Charite Campus Virchow, Berlin, Germany
    Ann Transplant 9:72-3. 2004
    ..Although our experimental data need to be confirmed clinically, they suggest a modified and age-adapted immunosuppression in elderly recipients during the early posttransplant period...
  20. ncbi request reprint Enzyme-linked immunosorbent spot assay for donor-reactive interferon-gamma-producing cells identifies T-cell presensitization and correlates with graft function at 6 and 12 months in renal-transplant recipients
    Peter Nickel
    Department of Nephrology and Intensive Care, Charite Campus Virchow, Augustenburger Platz 1, D 13353 Berlin, Germany
    Transplantation 78:1640-6. 2004
    ..A major goal in clinical transplantation is the individualization of immunosuppression. This requires a definition of markers that identify patients at heightened risk of acute rejection and immune-mediated chronic allograft nephropathy...
  21. ncbi request reprint Hypertension increases expression of growth factors and MHC II in chronic allograft nephropathy
    Ralf Schindler
    Department of Nephrology and Internal Intensive Care Medicine, Universitatsklinikum Charite, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
    Kidney Int 63:2302-8. 2003
    ..Hypertension of the recipient is strongly associated with chronic allograft nephropathy. It is unclear, however, whether hypertension is the cause or the consequence of chronic allograft nephropathy...
  22. ncbi request reprint Probiotics partly reverse increased bacterial translocation after simultaneous liver resection and colonic anastomosis in rats
    Daniel Seehofer
    Department of General, Visceral, and Transplant Surgery, Charite, Campus Virchow, Humboldt University of Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    J Surg Res 117:262-71. 2004
    ..Bacterial translocation is one important cause of nosocomial infections following major abdominal surgery. Oral administration of probiotics has been proposed to diminish bacterial translocation...
  23. ncbi request reprint Preoperative evaluation of living kidney donors using multirow detector computed tomography: comparison with digital subtraction angiography and intraoperative findings
    Enrique Lopez Hänninen
    Department of Radiology, Charite Medical University Center, Campus Virchow Clinic, Augustenburger Platz 1, D 13353 Berlin, Germany
    Transpl Int 18:1134-41. 2005
    ....
  24. ncbi request reprint Microscopic tumor cell dissemination in gastric cancer
    Sven Jonas
    Department of General, Visceral, and Transplantation Surgery, Charite Campus Virchow Klinikum, Humboldt University Berlin, Augustenburger Platz 1, D 13353, Berlin, Germany
    Surg Today 34:101-6. 2004
    ..We herein investigate such dissemination, predominantly restricted to the subserosa, in patients with gastric cancer...
  25. ncbi request reprint Brain death associated ischemia/reperfusion injury
    Johann Pratschke
    Department of General, Visceral and Transplantation Surgery, Universitatsmedizin, Charite, Campus Virchow, Berlin, Germany
    Ann Transplant 9:78-80. 2004
    ..Eventually, attentuation of I/R by strategies interfering with the different processes promoted by this insult may constitute a means to improve both short and long-term graft outcome...
  26. ncbi request reprint Promising recent data on ABO incompatible liver transplantation: restrictions may apply
    Johann Pratschke
    Department of General, Visceral and Transplantation Surgery, Humboldt University Berlin, Charite, Campus Virchow, Berlin, Germany
    Transpl Int 20:647-8. 2007
  27. ncbi request reprint Increased mortality after liver transplantation for hepatocellular carcinoma in hepatitis B-associated cirrhosis
    Sven Jonas
    Department of General, Visceral, and Transplantation Surgery, Charite Campus Virchow Klinikum, Humboldt University Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Transpl Int 16:33-6. 2003
    ..22%; P<0.05). This difference was due to unspecific causes, not to tumor recurrence or re-infection. These findings may be indicative of a more complicated course in patients suffering from hepatitis B in general...
  28. ncbi request reprint Pituitary function test and endocrine status in patient with cirrhosis of the liver before and after hepatic transplantation
    Daniel Seehofer
    Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Humboldt University of Berlin
    Ann Transplant 7:32-7. 2002
    ..We therefore performed extensive endocrine studies including a global pituitary stimulation test before and after liver transplantation...
  29. ncbi request reprint CMV hepatitis after liver transplantation: incidence, clinical course, and long-term follow-up
    Daniel Seehofer
    Department of General, Visceral, and Transplant Surgery, Charite Campus Virchow, Humboldt University of Berlin, Berlin, Germany
    Liver Transpl 8:1138-46. 2002
    ..Long-term complications of CMV hepatitis were not observed, and especially no correlation with chronic rejection was found...
  30. ncbi request reprint Immunisations in solid-organ transplant recipients
    Klaus Stark
    Institute of Tropical Medicine, Charite, Humboldt University, Berlin, Germany
    Lancet 359:957-65. 2002
    ..The major issues are the immunogenicity and safety of immunisations, the factors associated with poor immune response, and recommendations for immunisation schemes...
  31. ncbi request reprint Induction of carbon monoxide in donor animals prior to organ procurement reduces graft immunogenicity and inhibits chronic allograft dysfunction
    Paulo Ney Aguiar Martins
    Division of Transplant Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Transplantation 82:938-44. 2006
    ..Nonspecific inflammatory damages occurring prior to organ transplantation reduce long-term graft survival. Here, we tested the beneficial effects of carbon monoxide (CO) induction by methylene chloride (MC)...
  32. doi request reprint Impact of innate and adaptive immunity on rejection and tolerance
    Irene K Kim
    Division of Transplant Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Transplantation 86:889-94. 2008
    ..Ultimately, controlling the events in innate immune activation may help drive tolerance induction and reduce the rate of rejection...
  33. doi request reprint Donor postextubation hypotension and age correlate with outcome after donation after cardiac death transplantation
    Karen J Ho
    Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Transplantation 85:1588-94. 2008
    ..We hypothesized that donor postextubation parameters, including duration and severity of hemodynamic instability or hypoxia might be a better predictor of subsequent graft function...
  34. ncbi request reprint Modifying graft immunogenicity and immune response prior to transplantation: potential clinical applications of donor and graft treatment
    Paulo N A Martins
    Department of Surgery, Division of Transplant Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Transpl Int 19:351-9. 2006
    ..We review the results of experimental and clinical studies on donor or graft immunomodulation prior to transplantation and analyze the evidence to support clinical application of these strategies...
  35. ncbi request reprint Chronic allograft nephropathy
    Nidyanandh Vadivel
    Transplantation Research Center, Division of Nephrology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    Semin Nephrol 27:414-29. 2007
    ..This article highlights the importance of early identification and careful management of all the potential contributing factors with particular emphasis on prevention rather than cure of CAN as the core management strategy...
  36. ncbi request reprint TIRC7 is induced in rejected human kidneys and anti-TIRC7 mAb with FK506 prolongs survival of kidney allografts in rats
    Yusuke Kumamoto
    School of Medicine, Keio University, Tokyo, Japan
    Transpl Immunol 16:238-44. 2006
    ..Moreover, the identification of TIRC7 in graft infiltrating lymphocytes might serve as a diagnostic marker to detect allograft rejection...
  37. ncbi request reprint Induction therapy: are we picking our battles?
    Anil Chandraker
    Clin J Am Soc Nephrol 1:356-7. 2006
  38. ncbi request reprint Invasive fungal infections and antifungal therapies in solid organ transplant recipients
    Steven Gabardi
    Department of Pharmacy Services, Brigham and Women s Hospital, Boston, MA, USA
    Transpl Int 20:993-1015. 2007
    ..Transplant practitioners must remain aware of their therapeutic options and the advantages and disadvantages associated with the available treatment alternatives...