J F Stover

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    J Neurosurg 92:853-9. 2000
  2. ncbi Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-alpha in relation to brain edema and contusion following controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    Neurosci Lett 288:25-8. 2000
  3. ncbi Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Augustenburger Platz 01, D 13353 Berlin, Germany
    Brain Res 875:51-5. 2000
  4. ncbi Riluzole reduces brain swelling and contusion volume in rats following controlled cortical impact injury
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    J Neurotrauma 17:1171-8. 2000
  5. ncbi Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    J Neurosurg 94:782-7. 2001
  6. ncbi Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage
    O W Sakowitz
    Department of Neurosurgery, , Berlin, Germany
    J Cereb Blood Flow Metab 21:1067-76. 2001
  7. ncbi Neuronal activity and cortical perfusion determined by quantitative EEG analysis and laser doppler flowmetry are uncoupled in brain injured rats
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    Acta Neurochir Suppl 89:81-5. 2004
  8. ncbi The antioxidant effect of N-acethylcysteine on experimental contusion in rats
    U W Thomale
    Department of Neurosurgery, Charite, Virchow Medical Center, University of Berlin, Berlin, Germany
    Acta Neurochir Suppl 95:429-31. 2005
  9. ncbi Assessment of the relationship between age and continuous intracranial compliance
    K L Kiening
    Department of Neurosurgery, Heidelberg Medical Center, Ruprecht Karls University, Heidelberg, Germany
    Acta Neurochir Suppl 95:293-7. 2005
  10. ncbi Differential effects of prolonged isoflurane anesthesia on plasma, extracellular, and CSF glutamate, neuronal activity, 125I-Mk801 NMDA receptor binding, and brain edema in traumatic brain-injured rats
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    Acta Neurochir (Wien) 146:819-30. 2004

Detail Information

Publications21

  1. ncbi Significant reduction in brain swelling by administration of nonpeptide kinin B2 receptor antagonist LF 16-0687Ms after controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    J Neurosurg 92:853-9. 2000
    ..The purpose of this study was to investigate the protective effect of the novel nonpeptide B2 receptor antagonist, LF 16-0687Ms, in brain-injured rats...
  2. ncbi Temporal profile of cerebrospinal fluid glutamate, interleukin-6, and tumor necrosis factor-alpha in relation to brain edema and contusion following controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    Neurosci Lett 288:25-8. 2000
    ..7+/-1 pg/ml) (P<0.005). The observed different temporal profile of CSF glutamate, IL-6, and TNF-alpha following focal traumatic brain injury could be of therapeutic importance...
  3. ncbi Increased cerebrospinal fluid glutamate and taurine concentrations are associated with traumatic brain edema formation in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Augustenburger Platz 01, D 13353 Berlin, Germany
    Brain Res 875:51-5. 2000
    ..Therefore, increasing taurine could be a therapeutic approach in attenuating post-traumatic glutamate-mediated cell damage...
  4. ncbi Riluzole reduces brain swelling and contusion volume in rats following controlled cortical impact injury
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    J Neurotrauma 17:1171-8. 2000
    ..Under the present study design, riluzole significantly reduced brain edema formation and contusion volume in rats subjected to a mild focal cortical contusion...
  5. ncbi Effects of tacrolimus on hemispheric water content and cerebrospinal fluid levels of glutamate, hypoxanthine, interleukin-6, and tumor necrosis factor-alpha following controlled cortical impact injury in rats
    J F Stover
    Department of Neurosurgery, Charite Virchow Medical Center, Berlin, Germany
    J Neurosurg 94:782-7. 2001
    ..The aims of the present study were to investigate time- and dose-dependent short-term antiedematous effects of tacrolimus following TBI...
  6. ncbi Relation of cerebral energy metabolism and extracellular nitrite and nitrate concentrations in patients after aneurysmal subarachnoid hemorrhage
    O W Sakowitz
    Department of Neurosurgery, , Berlin, Germany
    J Cereb Blood Flow Metab 21:1067-76. 2001
    ..On the basis of the current findings, however, subsequent development of DIND cannot be explained by a lack of vasodilatory NO alone...
  7. ncbi Neuronal activity and cortical perfusion determined by quantitative EEG analysis and laser doppler flowmetry are uncoupled in brain injured rats
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    Acta Neurochir Suppl 89:81-5. 2004
    ..Non-radioactive methods like quantitative EEG analysis and laser Doppler flowmetry can be used to reveal underlying uncoupling of EEG activity from cortical perfusion which is mostly sustained in the early phase following CCII...
  8. ncbi The antioxidant effect of N-acethylcysteine on experimental contusion in rats
    U W Thomale
    Department of Neurosurgery, Charite, Virchow Medical Center, University of Berlin, Berlin, Germany
    Acta Neurochir Suppl 95:429-31. 2005
    ..The antioxidant properties of NAC did not affect intracranial pressure or posttraumatic brain edema formation, although the moderate reduction of contusion volume might reveal beneficial effects on focal contusion...
  9. ncbi Assessment of the relationship between age and continuous intracranial compliance
    K L Kiening
    Department of Neurosurgery, Heidelberg Medical Center, Ruprecht Karls University, Heidelberg, Germany
    Acta Neurochir Suppl 95:293-7. 2005
    ..The observed phenomenon of decreased intracranial volume challenge compensation with advancing age may contribute to the well-known fact of a worse outcome in elderly patients after TBI...
  10. ncbi Differential effects of prolonged isoflurane anesthesia on plasma, extracellular, and CSF glutamate, neuronal activity, 125I-Mk801 NMDA receptor binding, and brain edema in traumatic brain-injured rats
    J F Stover
    Charité Department of Neurosurgery, Berlin, Germany
    Acta Neurochir (Wien) 146:819-30. 2004
    ....
  11. ncbi Cortical hypoperfusion precedes hyperperfusion following controlled cortical impact injury
    U W Thomale
    Department of Neurosurgery, Charite, Virchow Medical Center, Humboldt University of Berlin, Germany
    Acta Neurochir Suppl 81:229-31. 2002
    ..Cortical hypoperfusion found within the early phase following trauma is reversible and precedes a long lasting phase of hyperperfusion. Changes in tissue mediators (endothelin, acidosis, NO) could account for these findings...
  12. ncbi Granulocyte colony-stimulating factor does not affect contusion size, brain edema or cerebrospinal fluid glutamate concentrations in rats following controlled cortical impact
    O W Sakowitz
    Department of Neurosurgery, University of Heidelberg, Heidelberg, Germany
    Acta Neurochir Suppl 96:139-43. 2006
    ..In contrast, evidence of G-CSF neuroprotective effects has been reported in rodent models of focal cerebral ischemia. We investigated effects of G-CSF in acute focal traumatic brain injury (TBI) in rats...
  13. ncbi Visualization of rat pial microcirculation using the novel orthogonal polarized spectral (OPS) imaging after brain injury
    U W Thomale
    Department of Neurosurgery, , Virchow Medical Center, Humboldt-University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    J Neurosci Methods 108:85-90. 2001
    ..This technique opens the possibility to perform longitudinal studies investigating changes in pial microcirculation...
  14. ncbi Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat
    F K van Landeghem
    Institute of Neuropathology, Charite, Humboldt University, Berlin, Germany
    Glia 35:167-79. 2001
    ..Ramified microglia may play an important compensatory role in the early regulation of extracellular glutamate after CCII...
  15. ncbi Norepinephrine is superior to dopamine in increasing cortical perfusion following controlled cortical impact injury in rats
    S N Kroppenstedt
    Department of Neurosurgery, Charite, Virchow Medical Center, Humboldt University Berlin, Germany
    Acta Neurochir Suppl 81:225-7. 2002
    ..Norepinephrine, however, was superior to dopamine in CBF. Based on increased CBF and unchanged brain swelling catecholamine-mediated vasoconstriction does not seem to occur under the present study design...
  16. ncbi Temporal profiles of extracellular nitric oxide metabolites following aneurysmal subarachnoid hemorrhage
    O W Sakowitz
    Department of Neurosurgery, Charite Humboldt University Berlin, Berlin, Germany
    Acta Neurochir Suppl 81:351-4. 2002
    ..This is in agreement with hypothetical NO scavenging by products of hemolysis. However, subsequent development of DIND cannot be explained by a lack of vasodilatory NO alone...
  17. ncbi Continuous monitoring of intracranial compliance after severe head injury: relation to data quality, intracranial pressure and brain tissue PO2
    K L Kiening
    Department of Neurosurgery, Virchow Medical Centre, Charite, Humboldt University at Berlin, Germany
    Br J Neurosurg 17:311-8. 2003
    ..Based on the present results, we conclude that the current hardware and software version of the cICC monitoring system is unsatisfactory concerning data quality, prediction of increased ICP and revelance of cerebral hypoxic episodes...
  18. ncbi The use of neuronavigation in transnasal transsphenoidal pituitary surgery
    U W Thomale
    Department of Neurosurgery, Charite, Virchow Medical Center, Humboldt University Berlin, Germany
    Zentralbl Neurochir 66:126-32; discussion 132. 2005
    ..Recurrent pituitary adenomas and localisation of microadenomas potentially cause difficulties during transsphenoidal pituitary surgery. Neuronavigation might improve tumour removal in such cases...
  19. ncbi Noninvasive analysis of conjunctival microcirculation during carotid artery surgery reveals microvascular evidence of collateral compensation and stenosis-dependent adaptation
    K D Schaser
    Department of Trauma and Reconstructive Surgery, Charite, Campus Virchow Klinikum, Humboldt Universitat zu Berlin, Berlin, Germany
    J Vasc Surg 37:789-97. 2003
    ..We purposed to visualize and quantify ischemia/reperfusion-induced microcirculatory changes in the terminal vascular bed of the ICA in patients undergoing unilateral ICA endarterectomy...
  20. ncbi Pharmacology of traumatic brain injury
    N C Royo
    Head Injury Center, Department of Neurosurgery, University of Pennsylvania, 3320 Smith Walk, 105 C Hayden Hall, Philadelphia, PA 19104 6316, USA
    Curr Opin Pharmacol 3:27-32. 2003
    ....
  21. ncbi Neuronal activity determined by quantitative EEG and cortical microdialysis is increased following controlled cortical impact injury in rats
    O W Sakowitz
    Acta Neurochir Suppl 81:221-3. 2002
    ..c. glutamate concentrations. Therefore, neuronal activity needs to be considered for the interpretation of e.c. glutamate levels...