E Stockfleth

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Development of a treatment algorithm for actinic keratoses: a European Consensus
    Eggert Stockfleth
    Department of Dermatology, Charite Universitatsmedizin Berlin, Skin Cancer Center Charite, Chariteplatz 1, 10117 Berlin, Germany
    Eur J Dermatol 18:651-9. 2008
  2. ncbi request reprint The paradigm shift in treating actinic keratosis: a comprehensive strategy
    Eggert Stockfleth
    Skin Cancer Center, Charite, University Hospital, Berlin, Germany
    J Drugs Dermatol 11:1462-7. 2012
  3. pmc Eyebrow hairs from actinic keratosis patients harbor the highest number of cutaneous human papillomaviruses
    Ines Schneider
    Charite, Department of Dermatology, Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    BMC Infect Dis 13:186. 2013
  4. doi request reprint Recurrence rates and patient assessed outcomes of 0.5% 5-fluorouracil in combination with salicylic acid treating actinic keratoses
    Eggert Stockfleth
    Department of Dermatology, Berlin University Medical Centre, Berlin, Germany
    Eur J Dermatol 22:370-4. 2012
  5. doi request reprint The use of sinecatechins (polyphenon E) ointment for treatment of external genital warts
    Eggert Stockfleth
    Department of Dermatology, University of Berlin, Skin Cancer Center Charite, HTCC, Chariteplatz 1, 10117 Berlin, Germany
    Expert Opin Biol Ther 12:783-93. 2012
  6. pmc Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling
    Ingo Nindl
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    Mol Cancer 5:30. 2006
  7. ncbi request reprint The use of Toll-like receptor-7 agonist in the treatment of basal cell carcinoma: an overview
    E Stockfleth
    Department of Dermatology, University Hospital Charite, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Br J Dermatol 149:53-6. 2003
  8. ncbi request reprint Multicentre, open-label study using imiquimod 5% cream in one or two 4-week courses of treatment for multiple actinic keratoses on the head
    E Stockfleth
    Haut Tumor Centrum Charité Skin Cancer Center Charié, Klinik fur Dermatologie, Venerologie und Allergologie, Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Br J Dermatol 157:41-6. 2007
  9. ncbi request reprint Human papillomaviruses in transplant-associated skin cancers
    Eggert Stockfleth
    Department of Dermatology, Charite, University of Berlin, Germany
    Dermatol Surg 30:604-9. 2004
  10. doi request reprint Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results
    E Stockfleth
    Department of Dermatology, Venereology and Allergy, Berlin University Medical Centre, Charité Skin Cancer Centre, Berlin, Germany
    Br J Dermatol 165:1101-8. 2011

Collaborators

Detail Information

Publications103 found, 100 shown here

  1. doi request reprint Development of a treatment algorithm for actinic keratoses: a European Consensus
    Eggert Stockfleth
    Department of Dermatology, Charite Universitatsmedizin Berlin, Skin Cancer Center Charite, Chariteplatz 1, 10117 Berlin, Germany
    Eur J Dermatol 18:651-9. 2008
    ..This is a novel algorithm that has the capacity to grow and expand as more clinical evidence becomes available. It offers, for the first time, a summary of European best practice recommendations for the treatment of AK...
  2. ncbi request reprint The paradigm shift in treating actinic keratosis: a comprehensive strategy
    Eggert Stockfleth
    Skin Cancer Center, Charite, University Hospital, Berlin, Germany
    J Drugs Dermatol 11:1462-7. 2012
    ....
  3. pmc Eyebrow hairs from actinic keratosis patients harbor the highest number of cutaneous human papillomaviruses
    Ines Schneider
    Charite, Department of Dermatology, Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    BMC Infect Dis 13:186. 2013
    ..This study compares the presence of cutaneous HPV types in eyebrow hairs to those in tissues of normal skin and skin lesions of 75 immunocompetent AK patients...
  4. doi request reprint Recurrence rates and patient assessed outcomes of 0.5% 5-fluorouracil in combination with salicylic acid treating actinic keratoses
    Eggert Stockfleth
    Department of Dermatology, Berlin University Medical Centre, Berlin, Germany
    Eur J Dermatol 22:370-4. 2012
    ..Actinic keratoses (AK) have been classified as early in situ squamous cell carcinomas and should be treated...
  5. doi request reprint The use of sinecatechins (polyphenon E) ointment for treatment of external genital warts
    Eggert Stockfleth
    Department of Dermatology, University of Berlin, Skin Cancer Center Charite, HTCC, Chariteplatz 1, 10117 Berlin, Germany
    Expert Opin Biol Ther 12:783-93. 2012
    ..The 15% ointment has been approved for the topical treatment of condylomata acuminata (CA), caused by particular human papillomaviruses (HPV), mainly HPV types 6 and 11...
  6. pmc Identification of differentially expressed genes in cutaneous squamous cell carcinoma by microarray expression profiling
    Ingo Nindl
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    Mol Cancer 5:30. 2006
    ..Carcinogenesis is a multi-step process indicated by several genes up- or down-regulated during tumor progression. This study examined and identified differentially expressed genes in cutaneous squamous cell carcinoma (SCC)...
  7. ncbi request reprint The use of Toll-like receptor-7 agonist in the treatment of basal cell carcinoma: an overview
    E Stockfleth
    Department of Dermatology, University Hospital Charite, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Br J Dermatol 149:53-6. 2003
    ..Imiquimod 5% cream for the treatment of mainly superficial BCC appears to be an effective and well-tolerated treatment option...
  8. ncbi request reprint Multicentre, open-label study using imiquimod 5% cream in one or two 4-week courses of treatment for multiple actinic keratoses on the head
    E Stockfleth
    Haut Tumor Centrum Charité Skin Cancer Center Charié, Klinik fur Dermatologie, Venerologie und Allergologie, Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Br J Dermatol 157:41-6. 2007
    ..In the USA, Imiquimod 5% cream is approved for use 2-3 times per week over 16 weeks for the treatment of actinic keratoses (AKs). This study evaluated the efficacy of imiquimod in another treatment schedule, for AKs on the head...
  9. ncbi request reprint Human papillomaviruses in transplant-associated skin cancers
    Eggert Stockfleth
    Department of Dermatology, Charite, University of Berlin, Germany
    Dermatol Surg 30:604-9. 2004
    ..Human papillomavirus (HPV) infection has been suggested to be involved in the development of nonmelanoma skin cancer, the most common malignancy after solid-organ transplantation...
  10. doi request reprint Low-dose 5-fluorouracil in combination with salicylic acid as a new lesion-directed option to treat topically actinic keratoses: histological and clinical study results
    E Stockfleth
    Department of Dermatology, Venereology and Allergy, Berlin University Medical Centre, Charité Skin Cancer Centre, Berlin, Germany
    Br J Dermatol 165:1101-8. 2011
    ..Actinic keratoses (AKs) arise after chronic sun exposure. Because long-term ultraviolet (UV) damage may induce proliferation of atypical keratinocytes, treatment of AKs is recommended...
  11. doi request reprint Topical Polyphenon E in the treatment of external genital and perianal warts: a randomized controlled trial
    E Stockfleth
    Dermatology Department, Skin Cancer Center Chartié, 10117 Berlin, Germany
    Br J Dermatol 158:1329-38. 2008
    ..Polyphenon E (MediGene AG, Munich, Germany), a proprietary extract of green tea leaves, was therefore investigated for the topical treatment of this frequent viral disease...
  12. doi request reprint Prevention of non-melanoma skin cancer in organ transplant patients by regular use of a sunscreen: a 24 months, prospective, case-control study
    C Ulrich
    Department of Dermatology, Skin Cancer Center, Charite University Hospital, 10117 Berlin, Germany
    Br J Dermatol 161:78-84. 2009
    ..Despite encouraging reports of protective effects of broad-spectrum sunscreens in immunocompetent patients, evidence for the prevention of NMSC in immunocompromised patients is still missing...
  13. ncbi request reprint The role of apoptosis in therapy and prophylaxis of epithelial tumours by nonsteroidal anti-inflammatory drugs (NSAIDs)
    L F Fecker
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:25-33. 2007
    ..Detailed analysis of apoptosis pathways employed by diclofenac in these cells may help to improve therapeutic strategies and to overcome possible mechanisms that are involved in nonresponsiveness...
  14. doi request reprint Long-term follow-up of photodynamic therapy with a self-adhesive 5-aminolaevulinic acid patch: 12 months data
    R M Szeimies
    Department of Dermatology, Regensburg University Hospital, Franz Josef Strauss Allee 11, Regensburg, Germany
    Br J Dermatol 162:410-4. 2010
    ..Photodynamic therapy with a self-adhesive 5-aminolaevulinic acid (5-ALA) patch shows high efficacy rates in the treatment of mild to moderate actinic keratosis (AK) in short term trials...
  15. ncbi request reprint A randomised study of topical 5% imiquimod vs. topical 5-fluorouracil vs. cryosurgery in immunocompetent patients with actinic keratoses: a comparison of clinical and histological outcomes including 1-year follow-up
    N Krawtchenko
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital, Berlin, Germany
    Br J Dermatol 157:34-40. 2007
    ..Actinic keratoses (AK) frequently occur on sun-exposed skin and are considered as in situ squamous cell carcinoma. To date, no treatment algorithm exists for first or second line therapies due to the lack of comparative studies...
  16. pmc Topical immunomodulation under systemic immunosuppression: results of a multicentre, randomized, placebo-controlled safety and efficacy study of imiquimod 5% cream for the treatment of actinic keratoses in kidney, heart, and liver transplant patients
    C Ulrich
    Clinic for Dermatology of the Charité, Charite Hospital, Campus Mitte, Charite Platz 1, 10117 Berlin, Germany
    Br J Dermatol 157:25-31. 2007
    ..In this study the safety and efficacy of imiquimod 5% cream for the treatments of actinic keratoses in kidney, heart and liver transplant recipients is evaluated...
  17. ncbi request reprint Successful treatment of multiple actinic keratoses in organ transplant patients with topical 5% imiquimod: a report of six cases
    C Ulrich
    Department of Dermatology, University of Humboldt, Schittenhelmstrasse 7, Berlin, Germany
    Br J Dermatol 155:451-4. 2006
    ..Impaired wound healing and high recurrence rates in immunocompromised patients treated with destructive therapies such as cryosurgery or topical 5-fluorouracil represent frequently known complications...
  18. doi request reprint [Human papillomavirus-associated warts in organ transplant recipients. Incidence, risk factors, management]
    D Krüger-Corcoran
    Klinik fur Dermatologie, Venerologie und Allergologie, Hauttumorcentrum Charité HTCC, Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin
    Hautarzt 61:220-9. 2010
    ..The challenging management of warts in organ transplantation patients is reviewed...
  19. ncbi request reprint Treatment of multiple actinic keratoses with topical diclofenac 3% gel in organ transplant recipients: a series of six cases
    C Ulrich
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:40-2. 2007
    ....
  20. ncbi request reprint Successful treatment of actinic keratosis with imiquimod cream 5%: a report of six cases
    E Stockfleth
    Department of Dermatology, University of Kiel, Schittenhelmstrasse 7, D 24105 Kiel, Germany
    Br J Dermatol 144:1050-3. 2001
    ..Actinic keratoses (AK) are premalignant lesions, which are routinely treated by destructive procedures such as cryotherapy, electrodessication or topical 5-fluorouracil...
  21. ncbi request reprint Noninvasive diagnostic tools for nonmelanoma skin cancer
    M Ulrich
    Department of Dermatology, Charite University Medicine, Berlin, Germany
    Br J Dermatol 157:56-8. 2007
    ..While systematic clinical analyses are often lacking, recent reports have shown promising results for reflectance confocal microscopy (RCM) for diagnosis of actinic keratoses and basal cell carcinoma...
  22. doi request reprint High viral load of human wart-associated papillomaviruses (PV) but not beta-PV in cutaneous warts independent of immunosuppression
    A Kohler
    Charite, Department of Dermatology, Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 161:528-35. 2009
    ..A broad spectrum of human papillomaviruses (HPV) has been detected in warts from immunocompetent patients and a much more diverse range from immunosuppressed organ transplant recipients (OTR)...
  23. ncbi request reprint Cutaneous precancers in organ transplant recipients: an old enemy in a new surrounding
    C Ulrich
    Department of Dermatology, University Hospital Charite, Schumannstrasse 20 21, D 10117, Berlin, Germany
    Br J Dermatol 149:40-2. 2003
    ..As reduction of the immunosuppressive therapy is rarely practicable, other terms of prophylaxis and treatment, such as immune response modifiers, have to be considered...
  24. doi request reprint Comparison of UV-induced skin changes in sun-exposed vs. sun-protected skin- preliminary evaluation by reflectance confocal microscopy
    M Ulrich
    Department of Dermatology, Venerology and Allergy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Br J Dermatol 161:46-53. 2009
    ..Reflectance confocal microscopy represents a non-invasive imaging technique that allows the in- vivo characterization of the skin at near histological resolution...
  25. ncbi request reprint Viral warts in organ transplant recipients: new aspects in therapy
    T Schmook
    Department of Dermatology, University Hospital Charite, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Br J Dermatol 149:20-4. 2003
    ..A promising novel therapeutic agent is imiquimod, an immune response modifier. Clinical efficacy of imiquimod has been observed for different skin lesions, including viral warts in both immunocompetent and immunosuppressed patients...
  26. ncbi request reprint Differentiation between actinic keratoses and disseminated superficial actinic porokeratoses with reflectance confocal microscopy
    M Ulrich
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:47-52. 2007
    ..Distinct morphological features can be distinguished upon histopathological examination, but the use of non-invasive tools, such as reflectance confocal microscopy (RCM), may be an eligible alternative for confirmation of diagnosis...
  27. ncbi request reprint [Skin cancer after organ transplantation]
    M Hackethal
    Klinik fur Dermatologie, Venerologie und Allergologie, Charite, Humboldt Universitat Berlin
    Dtsch Med Wochenschr 131:1609-13. 2006
  28. ncbi request reprint Tenascin-C patterns and splice variants in actinic keratosis and cutaneous squamous cell carcinoma
    C Dang
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 155:763-70. 2006
    ..The mRNA expression and protein level of Tn-C including its various isoforms have not been investigated comprehensively so far in cutaneous squamous cell carcinoma (SCC) and the precursor lesion actinic keratosis (AK)...
  29. ncbi request reprint Management of actinic cheilitis using diclofenac 3% gel: a report of six cases
    C Ulrich
    Department of Dermatology, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:43-6. 2007
    ..Diclofenac 3% gel is used in the treatment of actinic keratosis (AK), but it has not been evaluated for the treatment of actinic cheilitis...
  30. doi request reprint Organ transplant recipients and skin cancer: assessment of risk factors with focus on sun exposure
    D Terhorst
    Department of Dermatology, Venerology and Allergology, Skin Cancer Center Charite, Charite Universitatsmedizin, Berlin, Germany
    Br J Dermatol 161:85-9. 2009
    ..A number of factors such as immunosuppression, age, ultraviolet radiation and skin type are considered as important in aetiology...
  31. ncbi request reprint Low prevalence of p53, p16(INK4a) and Ha-ras tumour-specific mutations in low-graded actinic keratosis
    I Nindl
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:34-9. 2007
    ..Different mutation rates of p53, p16(INK4a) and Ha-ras in cutaneous squamous cell carcinoma (SCC) and the earlier stage actinic keratosis (AK) have been reported...
  32. doi request reprint Reflectance confocal microscopy for noninvasive monitoring of therapy and detection of subclinical actinic keratoses
    M Ulrich
    Skin Cancer Center Charite, Department of Dermatology, Charite University Medicine, Berlin, Germany martina ulrich charite de
    Dermatology 220:15-24. 2010
    ..Actinic keratoses (AK) represent cutaneous carcinoma in situ and have previously been evaluated by reflectance confocal microscopy (RCM). Treatment of AK with imiquimod (IMIQ) 5% cream has been shown to 'highlight' subclinical lesions...
  33. ncbi request reprint Actinic keratoses: non-invasive diagnosis for field cancerisation
    M Ulrich
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:13-7. 2007
    ..In vivo reflectance confocal microscopy (RCM) has been used for evaluation of the morphological features of non-melanoma skin cancer (NMSC) and RCM evaluation parameters for the diagnosis of AKs have been reported...
  34. doi request reprint Non-invasive diagnosis and monitoring of actinic cheilitis with reflectance confocal microscopy
    M Ulrich
    Skin Cancer Center Charite, Department of Dermatology, Charite University Medicine Berlin
    J Eur Acad Dermatol Venereol 25:276-84. 2011
    ..Herein, we describe the applicability of RCM for the diagnosis of AC and for monitoring of treatment response of AC to diclofenac in hyaluronic acid...
  35. doi request reprint Skin cancer in organ transplant recipients--where do we stand today?
    C Ulrich
    Department of Dermatology, Charite Universitatsmedizin, Berlin, Germany
    Am J Transplant 8:2192-8. 2008
    ..Presently, randomized prospective studies assess the burden of new skin tumors, as well as graft and patient survival, in patients with one or several NMSC after the introduction of mTOR (mammalian target of rapamycin) inhibitors...
  36. doi request reprint UV-induced squamous cell carcinoma--a role for antiapoptotic signalling pathways
    P M Rodust
    Charite Universitatsmedizin Berlin, Department of Dermatology and Allergy, HTCC Skin Cancer Center Charité, 10117 Berlin, Germany
    Br J Dermatol 161:107-15. 2009
    ..The final unravelling of apoptosis regulation in epithelial skin cancer may allow the development of new targeted therapeutic strategies...
  37. doi request reprint A phase II dose-ranging study of topical resiquimod to treat actinic keratosis
    R M Szeimies
    Department of Dermatology, Regensburg University Hospital, Regensburg, Germany
    Br J Dermatol 159:205-10. 2008
    ..Resiquimod, a toll-like receptor 7 and 8 agonist, may be effective as a topical treatment of actinic keratosis (AK)...
  38. ncbi request reprint E6/E7 expression of human papillomavirus types in cutaneous squamous cell dysplasia and carcinoma in immunosuppressed organ transplant recipients
    C Dang
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    Br J Dermatol 155:129-36. 2006
    ..DNA of cutaneous human papillomavirus (HPV) types is frequently found in nonmelanoma skin cancer, and their E6 and E7 proteins can have transforming properties...
  39. ncbi request reprint Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification
    J Röwert-Huber
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:8-12. 2007
    ....
  40. ncbi request reprint [Skin diseases in organ transplant patients]
    C Ulrich
    Klinik fur Dermatologie, Venerologie und Allergologie, Charite, Humboldt Universitat Berlin, Germany
    Hautarzt 53:524-33. 2002
    ..The rapidly growing numbers of allograft recipients as well as the rising long term survival rates of these patients demand the provision of high quality interdisciplinary and dermatological care in this field...
  41. ncbi request reprint Does progression from actinic keratosis and Bowen's disease end with treatment: diclofenac 3% gel, an old drug in a new environment?
    M J Patel
    Department of Dermatology, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:53-6. 2007
    ..We report a series of five patients with BD, all treated with diclofenac 3% gel with clinical and histological clearance...
  42. doi request reprint Photoprotective properties of the fluorescent europium complex in UV-irradiated skin
    O Vogt
    Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Charite, Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 26:76-84. 2013
    ..The europium complex has proved to be an efficient UV filter with a low cyto- and phototoxic profile and therefore represents a potential candidate for use in sunscreen formulations...
  43. doi request reprint Optimization of photodynamic therapy with a novel self-adhesive 5-aminolaevulinic acid patch: results of two randomized controlled phase III studies
    A Hauschild
    Department of Dermatology, Venereology and Allergology, University of Kiel, Schittenhelmstr 7, D 24105 Kiel, Germany
    Br J Dermatol 160:1066-74. 2009
    ..Photodynamic therapy (PDT) is increasingly used for treatment of actinic keratoses (AKs) but is a cumbersome procedure. A thin self-adhesive patch (PD P 506 A) containing 5-aminolaevulinic acid (5-ALA) was developed to facilitate PDT...
  44. doi request reprint Getting in early: primary skin cancer prevention at 55 German kindergartens
    L A Stöver
    Department of Dermatology, Venerology and Allergology, Skin Cancer Centre Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    Br J Dermatol 167:63-9. 2012
    ..This is the first nationwide environmental education programme for sun safety designed to teach children in kindergartens and their caregivers how to protect themselves from overexposure to the sun...
  45. ncbi request reprint Pathology and pathobiology of actinic (solar) keratosis - an update
    J Roewert-Huber
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 157:18-20. 2007
    ..Australia has the highest skin cancer rate in the world. AKs are discovered in up to 40-50% of the Australian population older than 40 years.(7) AKs are the most common malignant lesion of the skin.(8-12)...
  46. ncbi request reprint Apoptosis pathways as promising targets for skin cancer therapy
    J Eberle
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 156:18-24. 2007
    ..Importantly, the involvement of the different pro-apoptotic pathways in specific tumour types needs to be unravelled and understood in order to evaluate drug effectiveness, as well as to modify and optimise therapeutic approaches...
  47. ncbi request reprint Self-administered topical 5% imiquimod for the treatment of common warts and molluscum contagiosum
    U R Hengge
    Department of Dermatology, Venereology and Allergology, University of Essen, Hufelandstrasse 55, 45122 Essen, Germany
    Br J Dermatol 143:1026-31. 2000
    ..Imiquimod, a novel topical immune response modifier, has been successfully used for the treatment of external anogenital warts...
  48. ncbi request reprint Epidemiology and aetiology of basal cell carcinoma
    J Roewert-Huber
    Department of Dermatology Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 157:47-51. 2007
    ..This review elucidates the risk factors for the development and for the progression of BCC leading to an improved understanding of this tumour...
  49. doi request reprint Distribution of bacteria in the epidermal layers and hair follicles of the human skin
    B Lange-Asschenfeldt
    Wound Care Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 24:305-11. 2011
    ..Our results point out the role of skin appendages as potential microbial reservoirs and the need to develop new antiseptic formulations that sufficiently penetrate into the hair follicles...
  50. doi request reprint Certification of sun protection practices in a German child day-care centre improves children's sun protection--the 'SunPass' pilot study
    W Aulbert
    Department of Dermatology, Charite, Skin Cancer Centre Charité, University Hospital of Berlin, Berlin, Germany
    Br J Dermatol 161:5-12. 2009
    ..Important targets are staff members and parents of the day-care centre, since sun protection of children depends directly on their knowledge and their attitude towards sun protection practices...
  51. doi request reprint Isolation and genomic characterization of the first Norway rat (Rattus norvegicus) papillomavirus and its phylogenetic position within Pipapillomavirus, primarily infecting rodents
    Eric Schulz
    Clinic for Dermatology, Venereology and Allergology, Skin Cancer Center Charité HTCC, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Gen Virol 90:2609-14. 2009
    ..However, the derived Neogene origin of the genus Pipapillomavirus is much younger than has been considered for the Rodentia as the primary hosts, indicating that alternative interpretations of the phylogenetic trees should be conceived...
  52. doi request reprint [Precancerous tumors and carcinomas in situ of the skin]
    D Krüger-Corcoran
    Klinik fur Dermatologie, Venerologie und Allergologie, Hauttumorcentrum, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland
    Internist (Berl) 54:671-82. 2013
    ..Depending on the treatment process, different rates of general clearance and recurrence of the lesions are discussed in this article...
  53. ncbi request reprint Epithelial malignancies in organ transplant patients: clinical presentation and new methods of treatment
    E Stockfleth
    Department of Dermatology, Christian Albrechts University, Kiel, Germany
    Recent Results Cancer Res 160:251-8. 2002
    ..The drug has been shown to have both antiviral and antitumor activity. Application of immune response activators or modifiers such as imiquimod might be premising in the case of transplant recipients...
  54. ncbi request reprint Remarkable remission of a follicular lymphoma treated with rituximab and polychemotherapy (CHOP)
    T Schmook
    Department of Dermatology, University of Kiel, Germany
    Clin Exp Dermatol 28:31-3. 2003
    ..Follow-up biopsies on the forehead showed no evidence of CD20 positive lymphoma cells, now. Despite mild leucocytopaenia therapy was well tolerated...
  55. ncbi request reprint New treatment modalities for basal cell carcinoma
    E Stockfleth
    Department of Dermatology, Christian Albrechts University, Kiel, Germany
    Recent Results Cancer Res 160:259-68. 2002
    ..It also deals with two new treatment modalities, photodynamic therapy and imiquimod 5% cream, an immune response modifier that effectively resolves BCC lesions...
  56. ncbi request reprint Comparative epidemiology and pathogenic factors for nonmelanoma skin cancer in organ transplant patients
    Claas Ulrich
    Department of Dermatology, Charite Hospital, Berlin, Germany
    Dermatol Surg 30:622-7. 2004
    ..The goal of this review is to compare the epidemiologic prevalence of nonmelanoma skin cancer between various geographic locations and to highlight pathogenesis factors...
  57. ncbi request reprint Human papillomavirus and overexpression of P16INK4a in nonmelanoma skin cancer
    Ingo Nindl
    Charite, University of Berlin, Department of Dermatology, Berlin, Germany
    Dermatol Surg 30:409-14. 2004
    ..P16INK4a overexpression has been identified as a specific biomarker in high-risk human papillomavirus (HPV)-infected cervical (pre)cancer lesions...
  58. ncbi request reprint High sensitivity and reproducibility of immunohistochemistry with microagitation
    Ingo Nindl
    Charite, Department of Dermatology, 10117 Berlin, Germany
    Arch Dermatol Res 296:278-81. 2004
    ..Microagitation can be used for immunohistochemistry; it was reproducible, highly sensitive, and antibodies could be used at higher dilutions. Further analyses with other antibodies using this technique are warranted...
  59. doi request reprint Effects of a topically applied wound ointment on epidermal wound healing studied by in vivo fluorescence laser scanning microscopy analysis
    Bernhard Lange-Asschenfeldt
    Charite Universitatsmedizin Berlin, University Medical School, Department of Dermatology, Venerology and Allergology and Skin Cancer Center, Berlin, 10117, Germany
    J Biomed Opt 14:054001. 2009
    ..This technique allows monitoring of the kinetics of wound healing noninvasively and over time, while offering new insights into the potential effects of topically applied drugs on the process of tissue repair...
  60. doi request reprint Genomic characterization of a novel human papillomavirus (HPV-117) with a high viral load in a persisting wart
    Anja Köhler
    Charite, Department of Dermatology, Venereology and Allergy, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Virology 399:129-33. 2010
    ..The high viral load in dysplastic cells of a Verruca vulgaris was shown by in situ hybridization. Our results suggest an active role of the novel type in the development of cutaneous warts of OTR...
  61. ncbi request reprint Successful treatment of nephrogenic fibrosing dermopathy in a kidney transplant recipient with photodynamic therapy
    Tobias Schmook
    Department of Dermatology Skin Cancer Centre Charité, Charite University Hospital Berlin, Germany
    Nephrol Dial Transplant 20:220-2. 2005
  62. doi request reprint Preliminary evaluation of benign vascular lesions using in vivo reflectance confocal microscopy
    Susanne Astner
    Department of Dermatology, Venerology and Allergology, Charite University Medicine, Berlin, Germany
    Dermatol Surg 36:1099-110. 2010
    ..The applicability of RCM for various neoplastic and inflammatory skin diseases has been shown, but a descriptive evaluation of different vascular lesions has not yet been performed...
  63. doi request reprint Clinical applicability of in vivo reflectance confocal microscopy for the diagnosis of actinic keratoses
    Martina Ulrich
    Department of Dermatology, Charite University Medicine, Berlin, Germany
    Dermatol Surg 34:610-9. 2008
    ..The application of RCM for diagnosis of basal cell carcinoma has been reported; however, the evaluation of actinic keratoses (AKs) has only been the subject of preliminary studies...
  64. doi request reprint Emerging drugs for actinic keratosis
    Martina Ulrich
    Charite Universitatsmedizin Berlin, Skin Cancer Centre, Department of Dermatology, Chariteplatz 1, D 10117 Berlin, Germany
    Expert Opin Emerg Drugs 15:545-55. 2010
    ..In this regard, novel treatment modalities have been developed that allow treatment of the whole actinically damaged field...
  65. ncbi request reprint Azathioprine, UV light, and skin cancer in organ transplant patients--do we have an answer?
    Claas Ulrich
    Department of Dermatology, Skin Cancer Center Charite, Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Nephrol Dial Transplant 22:1027-9. 2007
  66. ncbi request reprint Identification of dysregulated genes in cutaneous squamous cell carcinoma
    Chantip Dang
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Oncol Rep 16:513-9. 2006
    ..02), while RPL15 and LGTN were down-regulated (p < 0.03). The genes differentially expressed during skin carcinogenesis may prove useful in order to understand the origin and progression of cutaneous SCC and for diagnostic approaches...
  67. ncbi request reprint Phylogenetic analysis of beta-papillomaviruses as inferred from nucleotide and amino acid sequence data
    Marc Gottschling
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    Mol Phylogenet Evol 42:213-22. 2007
    ..Thus, host and virus phylogenies were not congruent in beta-papillomaviruses, and multiple invasions across species borders may contribute (additionally to host-linked evolution) to their diversification...
  68. ncbi request reprint Current state of vitiligo therapy--evidence-based analysis of the literature
    Tobias Forschner
    Department of Dermatology, Venereology and Allergy, Charite Universitatsmedizin Berlin, Germany
    J Dtsch Dermatol Ges 5:467-75. 2007
    ..Our analysis compares these therapies for vitiligo and the evidence levels supporting their effectiveness...
  69. ncbi request reprint Extension of the typing in a general-primer-PCR reverse-line-blotting system to detect all 25 cutaneous beta human papillomaviruses
    Ingo Nindl
    Department of Dermatology, Venereology and Allergy, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    J Virol Methods 146:1-4. 2007
    ..Six beta-HPV types were added successfully to the typing format of the BGC-PCR/RLB system. The potential role of these types in the development of non-melanoma skin cancer awaits further studies...
  70. pmc Human papillomaviruses and non-melanoma skin cancer: basic virology and clinical manifestations
    Ingo Nindl
    Department of Dermatology, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Chariteplatz 1, D 10117 Berlin, Germany
    Dis Markers 23:247-59. 2007
    ..Thus, specific EV/cutaneous HPV types as co-factors in association with UV-radiation and the immune system seem to be involved in the early pathogenesis of cutaneous SCC...
  71. doi request reprint Peritumoral clefting in basal cell carcinoma: correlation of in vivo reflectance confocal microscopy and routine histology
    Martina Ulrich
    Department of Dermatology, Skin Cancer Center Charite, Charite University Medicine, Berlin, Germany
    J Cutan Pathol 38:190-5. 2011
    ....
  72. doi request reprint Health literacy, sunscreen and sunbed use: an uneasy association
    E Altsitsiadis
    Department of Dermatology, Venerology and Allergology, Skin Cancer Centre Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    Br J Dermatol 167:14-21. 2012
    ..Health literacy is receiving increasing attention, but its effect on tanning decisions has not yet been explored...
  73. ncbi request reprint Topical management of actinic keratosis and field cancerisation
    E Stockfleth
    Skin Cancer Center, Charite, University Hospital, Berlin, Germany
    G Ital Dermatol Venereol 144:459-62. 2009
    ..Overall the treatment choice is based on several factors, including location and number of lesions, growth and morphology, area of sun-damaged skin, age, lifestyle, and factors related to previous treatment or patient history...
  74. doi request reprint Clinical applicability of in vivo fluorescence confocal microscopy for noninvasive diagnosis and therapeutic monitoring of nonmelanoma skin cancer
    Susanne Astner
    Charite Universitatsmedizin Berlin, University Medical School, Department of Dermatology, Venerology and Allergology and Skin Cancer Center, 100117 Berlin, Germany
    J Biomed Opt 13:014003. 2008
    ..The findings are of preliminary nature and warrant further investigations in the future...
  75. doi request reprint Genomic characterization of the first insectivoran papillomavirus reveals an unusually long, second non-coding region and indicates a close relationship to Betapapillomavirus
    Eric Schulz
    Clinic for Dermatology, Venereology and Allergology, Skin Cancer Center Charité HTCC, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Gen Virol 90:626-33. 2009
    ..Our results underscore the modular organization of the PV genome and the complex natural history of PV...
  76. doi request reprint Cutaneotropic human beta-/gamma-papillomaviruses are rarely shared between family members
    Marc Gottschling
    Department of Dermatology, Venereology and Allergy, Charite, Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    J Invest Dermatol 129:2427-34. 2009
    ..Cutaneotropic HPV types are occasionally exchanged between family members during the entire lifetime, but other donors should also be considered in viral transmission...
  77. ncbi request reprint Multiple evolutionary mechanisms drive papillomavirus diversification
    Marc Gottschling
    Skin Cancer Center Charite, University Hospital of Berlin, Berlin, Germany
    Mol Biol Evol 24:1242-58. 2007
    ..The molecular data globally supports a complex evolutionary scenario for PVes, which is driven by multiple mechanisms but not exclusively by coevolution with corresponding hosts...
  78. doi request reprint Photoprotection in immunocompetent and immunocompromised people
    C Surber
    Department of Dermatology, Basel University Hospital, Petersgraben 4, CH 4031 Basel, Switzerland
    Br J Dermatol 167:85-93. 2012
    ..Certain persistent misconceptions and mistakes regarding photoprotection are also addressed...
  79. doi request reprint Open label randomized study comparing 3 months vs. 6 months treatment of actinic keratoses with 3% diclofenac in 2.5% hyaluronic acid gel: a trial of the German Dermatologic Cooperative Oncology Group
    A Pflugfelder
    Centre for Dermatooncology, Department of Dermatology, University Hospital Tuebingen, Berlin, Germany
    J Eur Acad Dermatol Venereol 26:48-53. 2012
    ..5% hyaluronic acid gel (HA) is effective and well tolerated in the treatment of AK. To date there are no large randomized multicentre trials with treatment durations longer than 90 days and histopathological control of treatment outcome...
  80. ncbi request reprint Successful topical treatment of focal epithelial hyperplasia (Heck's disease) with interferon-beta
    M Steinhoff
    Department of Dermatology, University of Munster, Von Esmarch Str 56, 48129 Munster, Germany
    Br J Dermatol 144:1067-9. 2001
    ..Topical treatment with interferon-beta appears to be an effective, simple, non-invasive, cheap and low-risk alternative to other invasive or surgical therapeutic modalities...
  81. ncbi request reprint Field treatment of actinic keratoses - focus on COX-2-inhibitors
    M Ulrich
    Department of Dermatology, Venerology and Allergy, Charite Universitatsmedizin, Berlin
    Actas Dermosifiliogr 100:55-8. 2009
    ..Herein, we give an overview about actinic keratosis focusing on treatment with the COX-2 inhibitor diclofenac 3 % gel and summarize current concepts of its antineoplastic mode of action...
  82. doi request reprint Results of a randomized, placebo-controlled safety and efficacy study of topical diclofenac 3% gel in organ transplant patients with multiple actinic keratoses
    Claas Ulrich
    Skin Cancer Centre Charité, Department of Dermatology, Charite Universitatsmedizin, Charite Platz 1, 10117 Berlin, Germany
    Eur J Dermatol 20:482-8. 2010
    ..This study suggests that diclofenac 3% gel is not only an efficient and well tolerated treatment for multiple AKs in OTRs but also may prevent invasive SCC in these high-risk patients...
  83. doi request reprint Novel papillomavirus isolates from Erinaceus europaeus (Erinaceidae, Insectivora) and the Cervidae (Artiodactyla), Cervus timorensis and Pudu puda, and phylogenetic analysis of partial sequence data
    Marc Gottschling
    Klinik fur Dermatologie, Charite, Haut Tumor Centrum Charité, Universitätskrankenhaus Berlin, Berlin, Germany
    Virus Genes 36:281-7. 2008
    ....
  84. ncbi request reprint Guidelines for the management of actinic keratoses
    Eggert Stockfleth
    Department of Dermatology, Venerology and Allergology, Charite Campus Mitte, Universität Berlin Charitéplatz 1, 10117 Berlin, Germany
    Eur J Dermatol 16:599-606. 2006
  85. ncbi request reprint Successful treatment of basal cell carcinomas in a nevoid basal cell carcinoma syndrome with topical 5% imiquimod
    Eggert Stockfleth
    Department of Dermatology of the Charite, Humboldt University, Schumannstra e 20 21, 10117 Berlin, Germany
    Eur J Dermatol 12:569-72. 2002
    ..Patients were successfully cleared of BCCs after treatment for 6-8 weeks. Histologically no apparent signs of BCC-persistence could be detected and no recurrences were detected during the 12 month follow up period...
  86. doi request reprint Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP
    Lothar F Fecker
    Department of Dermatology and Allergy, HTCC Skin Cancer Center Charité, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Invest Dermatol 130:2098-109. 2010
    ..Thus, induction of apoptosis appears to be highly characteristic of the mode of action of diclofenac/HA, and the therapeutic effect may be related to sensitization of neoplastic keratinocytes for death ligand-induced apoptosis...
  87. doi request reprint Effective photodynamic therapy of actinic keratoses on the head and face with a novel, self-adhesive 5-aminolaevulinic acid patch
    Axel Hauschild
    Department of Dermatology, Allergology and Venerology, University of Kiel, Kiel, Germany
    Exp Dermatol 18:116-21. 2009
    ..Photodynamic therapy (PDT) is increasingly used for the treatment of actinic keratosis (AK)...
  88. ncbi request reprint A randomized, double-blind, vehicle-controlled study to assess 5% imiquimod cream for the treatment of multiple actinic keratoses
    Eggert Stockfleth
    Department of Dermatology, University of Kiel, Germany
    Arch Dermatol 138:1498-502. 2002
    ..Several case studies published recently have indicated that 5% imiquimod cream, currently licensed for the treatment of genital warts, may be an effective treatment for AK...
  89. doi request reprint The angiogenesis inhibitor thrombospondin-1 inhibits acute cutaneous hypersensitivity reactions
    Paula Velasco
    Department of Dermatology, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany
    J Invest Dermatol 129:2022-30. 2009
    ..Our results indicate that TSP-1 downregulates cutaneous delayed-type hypersensitivity reactions by acting on several distinct pathways mediating skin inflammation...
  90. ncbi request reprint Skin infections in organ transplant recipients
    Claas Ulrich
    Department of Dermatology, Allergy, Venereology, Charite University Hospital, Berlin, Germany
    J Dtsch Dermatol Ges 6:98-105. 2008
    ..Dermatological care of organ transplant recipients using appropriate diagnostic methods adapted to the modified clinical pattern may lead to early adequate treatment...
  91. pmc Keratotic skin lesions and other risk factors are associated with skin cancer in organ-transplant recipients: a case-control study in The Netherlands, United Kingdom, Germany, France, and Italy
    Jan N Bouwes Bavinck
    Department of Dermatology, Leiden University Medical Center, Leiden, The Netherlands
    J Invest Dermatol 127:1647-56. 2007
    ....
  92. ncbi request reprint Low incidence of new actinic keratoses after topical 5% imiquimod cream treatment: a long-term follow-up study
    Eggert Stockfleth
    Arch Dermatol 140:1542. 2004
  93. ncbi request reprint Persistence of Mastomys natalensis papillomavirus in multiple organs identifies novel targets for infection
    Julia Nafz
    Forschungsschwerpunkt Angewandte Tumorvirologie, Abteilung Virale Transformationsmechanismen, Deutsches Krebsforschungszentrum DKFZ, Heidelberg, Germany
    J Gen Virol 88:2670-8. 2007
    ..coucha is not only useful to study papillomavirus-induced skin carcinogenesis, but may also serve as a model to identify additional, still unknown target cells of papillomavirus infections and the potential pathological impact...
  94. doi request reprint Photodynamic therapy with methyl aminolevulinate for prevention of new skin lesions in transplant recipients: a randomized study
    Ann Marie Wennberg
    Department of Dermatology, Sahlgrenska University Hospital, Gothenburg University, Gothenburg, Sweden
    Transplantation 86:423-9. 2008
    ..Repeated field photodynamic therapy using topical methyl aminolevulinate (MAL) may have potential as a preventive treatment...
  95. ncbi request reprint Guidelines for the management of squamous cell carcinoma in organ transplant recipients
    Thomas Stasko
    Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Dermatol Surg 30:642-50. 2004
    ..There are few published studies or reviews, which provide guidance to the clinician in the treatment of these patients...
  96. ncbi request reprint Classification of human papillomavirus
    Thomas Meyer
    N Engl J Med 348:2040-1; author reply 2040-1. 2003
  97. doi request reprint A novel rodent papillomavirus isolated from anogenital lesions in its natural host
    Julia Nafz
    Applied Tumorvirology, Division Viral Transformation Mechanisms, German Cancer Research Center, Heidelberg, Germany
    Virology 374:186-97. 2008
    ..To date, McPV2 is the first rodent papillomavirus found in anogenital lesions...
  98. ncbi request reprint Association of human papillomavirus infections with cutaneous tumors in immunosuppressed patients
    Thomas Meyer
    Institute of Immunology, Clinical Pathology and Molecular Medicine, Lademannbogen 61, 22339, Hamburg, Germany
    Transpl Int 16:146-53. 2003
    ..All HPV 5- and HPV 8-positive SCCs were from immunosuppressed patients, indicating that infection with HPV 5 and HPV 8 may present an increased risk of SCC development in these patients...
  99. doi request reprint Sunscreens in organ transplant patients
    Claas Ulrich
    Nephrol Dial Transplant 23:1805-8. 2008
  100. ncbi request reprint Verrucae in a multicolored decorative tattoo
    Uwe Trefzer
    J Am Acad Dermatol 50:478-9. 2004
  101. ncbi request reprint Specialty clinics for the dermatologic care of solid-organ transplant recipients
    Leslie J Christenson
    Department of Dermatology, Mayo Clinic, Rochester, Minnesota 55905, USA
    Dermatol Surg 30:598-603. 2004
    ..Solid-organ transplant recipients constitute a complex patient population that experiences numerous and aggressive skin cancers. Proactive, comprehensive, ongoing, and effective dermatologic care of these patients is a necessity...