Michael SchuppSummaryAffiliation: Humboldt University Country: Germany Publications
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Publications
Endogenous ligands for nuclear receptors: digging deeperMichael Schupp
Department of Endocrinology, Diabetes, and Nutrition and Center for Cardiovascular Research, Institute of Pharmacology, Charite University Medicine Berlin, 10115 Berlin, Germany
J Biol Chem 285:40409-15. 2010..This knowledge about the nature and physiology of these ligands may create new opportunities for therapeutic drug development...
Angiotensin type 1 receptor antagonists induce human in-vitro adipogenesis through peroxisome proliferator-activated receptor-gamma activationJurgen Janke
Medical Faculty of the Charite, Franz Volhard Clinic, HELIOS Klinikum Berlin, Berlin, Germany
J Hypertens 24:1809-16. 2006..In clonal animal cells, certain angiotensin receptor blockers (ARB) activate the peroxisome proliferator-activated receptor-gamma (PPARgamma). The aim of this work was to validate that observation in human cells and humans...
Telmisartan: from lowering blood pressure to end-organ protectionThomas Unger
Charite University Medicine Berlin, Center for Cardiovascular Research CCR Institute of Pharmacology and Toxicology Hessische Strasse 3 4, 10115 Berlin, Germany
Future Cardiol 1:7-15. 2005..Due to its long duration of action, it compares favorably with other angiotensin receptor blockers. Latest data from clinical trials and newest research regarding telmisartan will be reviewed in this article...
Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartanMarkus Clemenz
Center for Cardiovascular Research, Institute of Pharmacology, Charite Universitatsmedizin Berlin, Hessische Str 3 4, 10115 Berlin, Germany
Diabetes 57:1405-13. 2008..Activation of the PPARalpha ligand binding domain (LBD) was investigated using transactivation assays...
