J Roth

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint [Diagnosis, prophylaxis and therapy of osteoporosis in juvenile idiopathic arthritis: consensus statement of the German Association for Pediatric Rheumatology]
    J Roth
    Pädiatrische Pneumologie und Immunologie, SPZ Rheumatologie, Charite Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Z Rheumatol 66:434-40. 2007
  2. ncbi request reprint Musculoskeletal abnormalities in juvenile idiopathic arthritis--a 4-year longitudinal study
    J Roth
    Charite Virchow Klinikum, SPZ Rheumatologie, Augustenburger Platz 1, 13353 Berlin, Germany
    Rheumatology (Oxford) 46:1180-4. 2007
  3. ncbi request reprint Musculoskeletal abnormalities of the forearm in patients with juvenile idiopathic arthritis relate mainly to bone geometry
    Johannes Roth
    University Children s Hospital, Tuebingen, Germany
    Arthritis Rheum 50:1277-85. 2004
  4. ncbi request reprint Osteoporosis in juvenile idiopathic arthritis--a practical approach to diagnosis and therapy
    Johannes Roth
    Department of Pediatric Pneumology and Immunology, Charite University Medicine, Berlin, Germany
    Eur J Pediatr 166:775-84. 2007
  5. ncbi request reprint Uncommon synovial cysts in children
    Johannes Roth
    Pediatric Rheumatology, Charite Universitaetsmedizin, Berlin, Germany
    Eur J Pediatr 165:178-81. 2006
  6. ncbi request reprint The clinical course of a child with CINCA/NOMID syndrome improved during and after treatment with thalidomide
    T Kallinich
    Department of Paediatrics, Pulmonology and Immunology, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Scand J Rheumatol 34:246-9. 2005
  7. doi request reprint Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever
    Tilmann Kallinich
    Department of Pediatric Pneumology and Immunology, Charite Universitaetsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany
    Ann Rheum Dis 69:677-82. 2010
  8. ncbi request reprint Panoramic X-rays. Comprehensive radiodiagnostics or radiation protection at all costs?
    Helga Landau
    Department of Orthodontics and Dentofacial Orthopedics, Charite University Medicine Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, Germany
    J Orofac Orthop 66:78-82. 2005
  9. doi request reprint Dynamics of body composition and bone in patients with juvenile idiopathic arthritis treated with growth hormone
    Susanne Bechtold
    Division of Pediatric Endocrinology, University Children s Hospital, D 80337 Munich, Germany
    J Clin Endocrinol Metab 95:178-85. 2010
  10. doi request reprint Natural history of growth and body composition in juvenile idiopathic arthritis
    S Bechtold
    Division of Pediatric Endocrinology, University Children s Hospital, Munich, Germany
    Horm Res 72:13-9. 2009

Collaborators

Detail Information

Publications37

  1. ncbi request reprint [Diagnosis, prophylaxis and therapy of osteoporosis in juvenile idiopathic arthritis: consensus statement of the German Association for Pediatric Rheumatology]
    J Roth
    Pädiatrische Pneumologie und Immunologie, SPZ Rheumatologie, Charite Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Z Rheumatol 66:434-40. 2007
    ..In this review, the diagnostic and therapeutic options are described and summarized in an algorithm...
  2. ncbi request reprint Musculoskeletal abnormalities in juvenile idiopathic arthritis--a 4-year longitudinal study
    J Roth
    Charite Virchow Klinikum, SPZ Rheumatologie, Augustenburger Platz 1, 13353 Berlin, Germany
    Rheumatology (Oxford) 46:1180-4. 2007
    ..The most prominent changes are a reduction in muscle cross sectional area (CSA) and muscle force. The aim of this study was to assess the evolution of these changes throughout the course of the disease...
  3. ncbi request reprint Musculoskeletal abnormalities of the forearm in patients with juvenile idiopathic arthritis relate mainly to bone geometry
    Johannes Roth
    University Children s Hospital, Tuebingen, Germany
    Arthritis Rheum 50:1277-85. 2004
    ..This study was undertaken to obtain a more detailed understanding of the musculoskeletal system in JIA by analyzing bone density, bone geometry, and muscle force as the most important factor in bone development...
  4. ncbi request reprint Osteoporosis in juvenile idiopathic arthritis--a practical approach to diagnosis and therapy
    Johannes Roth
    Department of Pediatric Pneumology and Immunology, Charite University Medicine, Berlin, Germany
    Eur J Pediatr 166:775-84. 2007
    ..In this review, diagnostic and therapeutic options are being described and possibilities to incorporate them into clinical practice are suggested...
  5. ncbi request reprint Uncommon synovial cysts in children
    Johannes Roth
    Pediatric Rheumatology, Charite Universitaetsmedizin, Berlin, Germany
    Eur J Pediatr 165:178-81. 2006
    ..Ultrasonography is the initial and follow-up imaging method of choice, which can be supplemented by MRI in unusual cases. Apart from treatment for arthritis, no specific therapeutic interventions were required in the present cases...
  6. ncbi request reprint The clinical course of a child with CINCA/NOMID syndrome improved during and after treatment with thalidomide
    T Kallinich
    Department of Paediatrics, Pulmonology and Immunology, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Scand J Rheumatol 34:246-9. 2005
    ..We propose that thalidomide can be beneficial in select patients with CINCA syndrome...
  7. doi request reprint Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever
    Tilmann Kallinich
    Department of Pediatric Pneumology and Immunology, Charite Universitaetsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany
    Ann Rheum Dis 69:677-82. 2010
    ..The aim of this study was to analyse the role of S100A12 in the detection of inflammation in patients with FMF...
  8. ncbi request reprint Panoramic X-rays. Comprehensive radiodiagnostics or radiation protection at all costs?
    Helga Landau
    Department of Orthodontics and Dentofacial Orthopedics, Charite University Medicine Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, Berlin, Germany
    J Orofac Orthop 66:78-82. 2005
    ..This example of juvenile idiopathic arthritis with TMJ involvement shows that visualization of the condylar processes is indispensable...
  9. doi request reprint Dynamics of body composition and bone in patients with juvenile idiopathic arthritis treated with growth hormone
    Susanne Bechtold
    Division of Pediatric Endocrinology, University Children s Hospital, D 80337 Munich, Germany
    J Clin Endocrinol Metab 95:178-85. 2010
    ..The objectives of this study were to demonstrate the effects of GH treatment on regional body composition and bone geometry at final height in patients with juvenile idiopathic arthritis (JIA)...
  10. doi request reprint Natural history of growth and body composition in juvenile idiopathic arthritis
    S Bechtold
    Division of Pediatric Endocrinology, University Children s Hospital, Munich, Germany
    Horm Res 72:13-9. 2009
    ..In recent years, the deficits in bone mass have been related, in part, to the deficits in muscle mass, which are prevalent in these patients...
  11. ncbi request reprint Similar effects of long-term exogenous growth hormone (GH) on bone and muscle parameters: a pQCT study of GH-deficient and small-for-gestational-age (SGA) children
    Roland Schweizer
    Paediatric Endocrinology Section, University Children s Hospital, Hoppe Seyler Strasse 1, D 72076, Tubingen, Germany
    Bone 41:875-81. 2007
    ..Treatment with GH in short children has focused on height development. Little is known about the concomitant changes in muscle mass, bone structure and bone strength...
  12. ncbi request reprint Determination of the peptide binding motif and high-affinity ligands for HLA-DQ4 using synthetic peptide libraries
    Thomas Volz
    University Children s Hospital, Tuebingen, Germany
    Hum Immunol 65:594-601. 2004
    ..It is, however, different from binding motifs of neutral or protective HLA-DQ molecules. Our results further support the idea of differential peptide presentation in the pathogenesis of oligoarthritic JIA...
  13. ncbi request reprint Monitoring neutrophil activation in juvenile rheumatoid arthritis by S100A12 serum concentrations
    Dirk Foell
    Institute of Experimental Dermatology and Department of Pediatrics, University of Muenster, Muenster, Germany
    Arthritis Rheum 50:1286-95. 2004
    ..The aim of our study was to determine neutrophil activation in juvenile rheumatoid arthritis (JRA) by analyzing S100A12 (EN-RAGE; calgranulin C), a proinflammatory protein secreted by human neutrophils...
  14. ncbi request reprint Acute Kawasaki disease is associated with reverse regulation of soluble receptor for advance glycation end products and its proinflammatory ligand S100A12
    Helmut Wittkowski
    Interdisciplinary Centre for Clinical Research, Department of Pediatrics, University of Muenster, University Hospital, Albert Schweitzer Strasse 33, Muenster, Germany
    Arthritis Rheum 56:4174-81. 2007
    ..The aim of this study was to investigate circulating sRAGE in an acute inflammatory disorder and to compare these data directly with concentrations of the proinflammatory RAGE ligand S100A12...
  15. pmc Effects of intra-articular corticosteroids and anti-TNF therapy on neutrophil activation in rheumatoid arthritis
    Helmut Wittkowski
    Interdisciplinary Centre of Clinical Research, University of Munster, Röntgenstr 21, D 48149 Munster, Germany
    Ann Rheum Dis 66:1020-5. 2007
    ..The aim of this project was to analyse the effect of intra-articular corticosteroids or systemic anti-TNF treatment on synovial expression and serum levels of S100A12 in rheumatoid arthritis (RA)...
  16. ncbi request reprint Bone mass in adolescents with early-onset juvenile idiopathic arthritis: comment on the article by Lien et al
    Johannes Roth
    Arthritis Rheum 50:2036. 2004
  17. ncbi request reprint Mechanisms of disease: a 'DAMP' view of inflammatory arthritis
    Dirk Foell
    Department of Pediatrics, University of Muenster, Muenster, Germany
    Nat Clin Pract Rheumatol 3:382-90. 2007
    ....
  18. ncbi request reprint Expression of myeloid-related protein-8 and -14 in patients with acute Kawasaki disease
    Keiich Hirono
    Department of Pediatrics, Toyama University, Toyama, Japan
    J Am Coll Cardiol 48:1257-64. 2006
    ..This study investigated patients with acute Kawasaki disease (KD) to validate myeloid-related protein (MRP)-8/MRP-14 as a marker of disease activity and severity of coronary artery lesion development...
  19. ncbi request reprint Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes
    Jan Ehrchen
    Institute of Experimental Dermatology, University of Muenster, Germany
    Blood 109:1265-74. 2007
    ..Thus, GC treatment did not cause a global suppression of monocytic effector functions but results in differentiation of a specific anti-inflammatory phenotype which seems to be actively involved in resolution of inflammatory reactions...
  20. ncbi request reprint Biophysical characterization of S100A8 and S100A9 in the absence and presence of bivalent cations
    Thomas Vogl
    Institute of Experimental Dermatology, University of Muenster, Roentgenstrasse 21, 48149 Muenster, Germany
    Biochim Biophys Acta 1763:1298-306. 2006
    ..The zinc-induced tetramer is structurally very similar to the calcium-induced tetramer. Thus, like calcium, zinc acts as a regulatory factor in S100A8/S100A9-dependent signaling pathways...
  21. ncbi request reprint Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock
    Thomas Vogl
    Institute of Experimental Dermatology, University of Munster, D 48129 Munster, Germany
    Nat Med 13:1042-9. 2007
    ..Therefore Mrp8-Mrp14 complexes are new inflammatory components that amplify phagocyte activation during sepsis upstream of TNFalpha-dependent effects...
  22. ncbi request reprint Calcium-dependent tetramer formation of S100A8 and S100A9 is essential for biological activity
    Nadja Leukert
    Institute of Experimental Dermatology, University of Muenster, Roentgenstr 21, 48149 Muenster, Germany
    J Mol Biol 359:961-72. 2006
    ..This is the first report showing a functional relevance of calcium-induced higher-order oligomerization in the S100 family...
  23. ncbi request reprint TNF induces distinct gene expression programs in microvascular and macrovascular human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology and Interdisciplinary Clinical Research Center, University of Munster, Röntgenstr 21, 48149 Munster, Germany
    J Leukoc Biol 80:174-85. 2006
    ..The establishment of EC type-specific expression patterns may thus provide the basis for a selective manipulation of specific endothelial subtypes in different inflammatory diseases...
  24. ncbi request reprint Increased perivascular synovial membrane expression of myeloid-related proteins in psoriatic arthritis
    David Kane
    Department of Rheumatology, St Vincent s University Hospital, Dublin, Ireland
    Arthritis Rheum 48:1676-85. 2003
    ....
  25. ncbi request reprint Expression of myeloid-related proteins 8 and 14 in systemic-onset juvenile rheumatoid arthritis
    Michael Frosch
    Institute of Experimental Dermatology and Department of Pediatrics, University of Munster, Munster, Germany
    Arthritis Rheum 48:2622-6. 2003
    ....
  26. ncbi request reprint Expression of MRP8 and MRP14 by macrophages is a marker for severe forms of glomerulonephritis
    Michael Frosch
    Institute of Experimental Dermatology, University of Munster, Röntgenstr 21, D 48149, Munster, Germany
    J Leukoc Biol 75:198-206. 2004
    ..In addition, our findings reflect differences in the inflammatory mechanisms underlying the various forms of GN, as they revealed that distinct macrophage subpopulations prevail in the different forms of GN...
  27. ncbi request reprint Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells
    Dorothee Viemann
    Department of Experimental Dermatology, University Hospital Munster, Muenster, Germany
    Blood 103:3365-73. 2004
    ..Thus, these results define a list of primary candidates for targeted modulation of endothelial functions during inflammation...
  28. pmc High expression of myeloid-related proteins 8 and 14 characterizes an inflammatorily active but ineffective response of macrophages during leprosy
    Cord H Sunderkötter
    Institute of Experimental Dermatology, University of Munster, Munster, Germany
    Immunology 111:472-80. 2004
    ....
  29. ncbi request reprint Phagocyte-specific calcium-binding S100 proteins as clinical laboratory markers of inflammation
    Dirk Foell
    Department of Pediatrics, University of Munster, Munster, Germany
    Clin Chim Acta 344:37-51. 2004
    ..In this review, pro-inflammatory functions of S100 proteins and their usefulness as biomarkers of inflammation are presented...
  30. ncbi request reprint Neutrophil-derived S100A12 is profoundly upregulated in the early stage of acute Kawasaki disease
    Fei Ye
    Department of Pediatrics, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0134, Japan
    Am J Cardiol 94:840-4. 2004
    ..S100A12 expression in neutrophils appears to reflect responsiveness to IVIG treatment and is possibly involved in the pathophysiology of acute vasculitis...
  31. ncbi request reprint Proinflammatory S100 proteins in arthritis and autoimmune disease
    Dirk Foell
    Interdisciplinary Center for Clinical Research, University of Muenster, Muenster, Germany
    Arthritis Rheum 50:3762-71. 2004
  32. ncbi request reprint Differential expression and response to anti-TNFalpha treatment of infiltrating versus resident tissue macrophage subsets in autoimmune arthritis
    Leen De Rycke
    Department of Rheumatology, Ghent University Hospital, Ghent, Belgium
    J Pathol 206:17-27. 2005
    ....
  33. ncbi request reprint Early activation of cutaneous vessels and epithelial cells is characteristic of acute systemic onset juvenile idiopathic arthritis
    Michael Frosch
    Institute of Experimental Dermatology, University of Munster, Germany
    Exp Dermatol 14:259-65. 2005
    ..Their differential expression further points to distinct roles of the individual molecules in inflammatory processes...
  34. ncbi request reprint Systemic juvenile rheumatoid arthritis: cognitive function and social adjustment
    Reinhold Feldmann
    Department of Pediatrics, University Hospital of Munster, Munster, Germany
    Ann Neurol 58:605-9. 2005
    ..Cognitive performance and social adjustment of young patients with SJRA are not affected by disease activity and duration...
  35. ncbi request reprint Expression of surfactant protein-C, S100A8, S100A9, and B cell markers in renal allografts: investigation of the prognostic value
    Michael Eikmans
    Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands
    J Am Soc Nephrol 16:3771-86. 2005
    ..Messenger RNA transcripts complement the biopsy in the prediction of graft function deterioration...
  36. ncbi request reprint Immunomodulatory effects of etanercept on peripheral joint synovitis in the spondylarthropathies
    Elli Kruithof
    Ghent University Hospital, Ghent, Belgium
    Arthritis Rheum 52:3898-909. 2005
    ....
  37. ncbi request reprint S100A12 (EN-RAGE) in monitoring Kawasaki disease
    Dirk Foell
    Department of Paediatrics, University Hospital Munster, Von Esmarch Str 58, 48149, Munster, Germany
    Lancet 361:1270-2. 2003
    ..0001). Since the interaction of S100A12 with multiligand receptors has a key role in inflammatory responses, this protein could serve as a novel target for future therapeutic interventions in inflammatory disorders...