Ursula Plockinger

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Guidelines for the diagnosis and treatment of neuroendocrine gastrointestinal tumours. A consensus statement on behalf of the European Neuroendocrine Tumour Society (ENETS)
    U Plockinger
    Department of Hepatology and Gastroenterology, Interdisciplinary Center for Metabolism, Endocrinology, and Diabetes, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Neuroendocrinology 80:394-424. 2004
  2. pmc Illness perception and clinical treatment experiences in patients with M. Maroteaux-Lamy (mucopolysaccharidosis type VI) and a Turkish migration background in Germany
    Hansjorg Dilger
    Institute of Social and Cultural Antropology, Freie Universitat Berlin, Berlin, Germany
    PLoS ONE 8:e66804. 2013
  3. pmc Medical therapy of acromegaly
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, 13353 Berlin, Germany
    Int J Endocrinol 2012:268957. 2012
  4. doi request reprint DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Endocrinol 166:223-34. 2012
  5. ncbi request reprint Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated tumour/carcinoma of the appendix and goblet cell carcinoma
    Ursula Plockinger
    Charite Universitatsmedizin, Campus Virchow Klinikum, Department of Hepatology and Gastroenterology, Berlin, Germany
    Neuroendocrinology 87:20-30. 2008
  6. ncbi request reprint Diagnosis and treatment of gastric neuroendocrine tumours
    Ursula Plockinger
    Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Charite Universitatsmedizin Berlin, Berlin, Germany
    Wien Klin Wochenschr 119:570-2. 2007
  7. doi request reprint Pegvisomant increases intra-abdominal fat in patients with acromegaly: a pilot study
    U Plockinger
    Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Med Klinik m S Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Endocrinol 158:467-71. 2008
  8. ncbi request reprint Risk of exercise-induced hypoglycaemia in patients with type 2 diabetes on intensive insulin therapy: comparison of insulin glargine with NPH insulin as basal insulin supplement
    Ursula Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Diabetes Res Clin Pract 81:290-5. 2008
  9. doi request reprint Problems of diabetes management in the immigrant population in Germany
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Med Klinik m S Hepatologie und Gastroenterologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Diabetes Res Clin Pract 87:77-86. 2010
  10. ncbi request reprint Treatment of gastroenteropancreatic neuroendocrine tumors
    U Plockinger
    Interdiziplinäres Stoffwechsel CentrumCharité, Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Virchows Arch 451:S71-80. 2007

Detail Information

Publications29

  1. ncbi request reprint Guidelines for the diagnosis and treatment of neuroendocrine gastrointestinal tumours. A consensus statement on behalf of the European Neuroendocrine Tumour Society (ENETS)
    U Plockinger
    Department of Hepatology and Gastroenterology, Interdisciplinary Center for Metabolism, Endocrinology, and Diabetes, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Neuroendocrinology 80:394-424. 2004
  2. pmc Illness perception and clinical treatment experiences in patients with M. Maroteaux-Lamy (mucopolysaccharidosis type VI) and a Turkish migration background in Germany
    Hansjorg Dilger
    Institute of Social and Cultural Antropology, Freie Universitat Berlin, Berlin, Germany
    PLoS ONE 8:e66804. 2013
    ..Of the thirty-one patients registered in Germany, almost fifty percent have a Turkish migration background. MPS VI is treated by enzyme replacement therapy (ERT), which is time-consuming and expensive...
  3. pmc Medical therapy of acromegaly
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, 13353 Berlin, Germany
    Int J Endocrinol 2012:268957. 2012
    ..Special emphasis is given to the difficulties to define remission criteria of acromegaly due to technical assay problems. An algorithm for medical therapy in acromegaly is provided...
  4. doi request reprint DG3173 (somatoprim), a unique somatostatin receptor subtypes 2-, 4- and 5-selective analogue, effectively reduces GH secretion in human GH-secreting pituitary adenomas even in Octreotide non-responsive tumours
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Endocrinol 166:223-34. 2012
    ..We investigated the effect of DG3173, including its relation to specific tumour characteristics, on GH secretion in human somatotroph adenoma cell cultures (hSA) in comparison with Octreotide...
  5. ncbi request reprint Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated tumour/carcinoma of the appendix and goblet cell carcinoma
    Ursula Plockinger
    Charite Universitatsmedizin, Campus Virchow Klinikum, Department of Hepatology and Gastroenterology, Berlin, Germany
    Neuroendocrinology 87:20-30. 2008
  6. ncbi request reprint Diagnosis and treatment of gastric neuroendocrine tumours
    Ursula Plockinger
    Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Charite Universitatsmedizin Berlin, Berlin, Germany
    Wien Klin Wochenschr 119:570-2. 2007
    ..They tend to occur earlier, without sex preference. These tumours may develop an aggressive course, with metastatic disease and an overall poor prognosis. Thus, aggressive surgical therapy is recommended...
  7. doi request reprint Pegvisomant increases intra-abdominal fat in patients with acromegaly: a pilot study
    U Plockinger
    Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Med Klinik m S Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Endocrinol 158:467-71. 2008
    ..We therefore studied intra-abdominal fat and insulin resistance in acromegalic patients after a 3-month octreotide-washout period, i.e., during untreated acromegaly, and during PEG treatment...
  8. ncbi request reprint Risk of exercise-induced hypoglycaemia in patients with type 2 diabetes on intensive insulin therapy: comparison of insulin glargine with NPH insulin as basal insulin supplement
    Ursula Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Diabetes Res Clin Pract 81:290-5. 2008
    ..This study compared the risk of exercise-related hypoglycaemia in type 2 diabetes patients receiving either basal insulin glargine or NPH insulin...
  9. doi request reprint Problems of diabetes management in the immigrant population in Germany
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Med Klinik m S Hepatologie und Gastroenterologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Diabetes Res Clin Pract 87:77-86. 2010
    ..To compare prospectively the effect of diabetes management in the immigrant and the native population in Berlin, Germany...
  10. ncbi request reprint Treatment of gastroenteropancreatic neuroendocrine tumors
    U Plockinger
    Interdiziplinäres Stoffwechsel CentrumCharité, Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    Virchows Arch 451:S71-80. 2007
    ..Biotherapy, its effects, and remaining uncertainties are presented as well as different chemotherapeutic schemes. Finally, new options of palliative medical therapies like kinase inhibitors and anti-angiogenetic drugs will be discussed...
  11. ncbi request reprint Endocrine tumours of the gastrointestinal tract. Management of metastatic endocrine tumours
    U Plockinger
    Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Medizinische Klinik m S Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Germany
    Best Pract Res Clin Gastroenterol 19:553-76. 2005
    ..The article will focus on the importance of each of these parameters for the various treatment options in patients with metastatic disease...
  12. ncbi request reprint Presurgical octreotide treatment in acromegaly: no improvement of final growth hormone (GH) concentration and pituitary function. A long-term case-control study
    U Plockinger
    Department of Hepatology and Gastroenterology, Interdisciplinary Centre of Metabolism Endocrinology, Diabetes and Metabolism, Charite, Campus Virchow Klinikum, Humboldt Universitat zu Berlin, Berlin, Germany
    Acta Neurochir (Wien) 147:485-93; discussion 493. 2005
    ..We evaluated in an acromegaly case-control study the effect of octreotide pre-treatment on short- and long-term postoperative GH concentrations, pituitary function and glucose tolerance...
  13. ncbi request reprint Neuroendocrine tumors. Biotherapy
    U Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Med Klinik m S Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, 13353 Berlin, Germany
    Best Pract Res Clin Endocrinol Metab 21:145-62. 2007
    ..This is followed by an in-depth description of the use of biotherapy, its results with respect to symptomatic and antiproliferative treatment, as well as its side-effects...
  14. ncbi request reprint Diagnosis of non-functioning neuro-endocrine gastro-enteropancreatic tumours
    Ursula Plockinger
    Medizinische Klinik m S Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Neuroendocrinology 80:35-8. 2004
    ..As the antiproliferative effect of biotherapy is still uncertain, it cannot yet be recommended as a routine treatment in non-functioning neuro-endocrine gastro-enteropancreatic tumours...
  15. ncbi request reprint [Neuroendocrine tumours of the gastrointestinal tract]
    U Plockinger
    Medizinische Klinik m S Hepatologie und Gastroenterologie, Interdisziplinäres Stoffwechselzentrum Endokrinologie und Diabetes, Charite, Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin
    Z Gastroenterol 42:517-27. 2004
    ..Cytoreductive strategies (chemoembolisation, thermo- or cryotherapy, cytoreductive surgery) and radio-receptor therapy may offer new therapeutic options. However, their definitive value has yet to be defined...
  16. ncbi request reprint Somatostatin receptor subtype-2-deficient mice with diet-induced obesity have hyperglycemia, nonfasting hyperglucagonemia, and decreased hepatic glycogen deposition
    Vandana Singh
    Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Interdisziplinares Stoffwechsel Centrum Endokrinologie, Diabetes und Stoffwechsel, Charite Universitatsmedizin, 13353 Berlin, Germany
    Endocrinology 148:3887-99. 2007
    ..Sst2 may constitute a therapeutic target to lower hyperglucagonemia in type 2 diabetes...
  17. ncbi request reprint Neuroendocrine tumor of the pancreas and bilateral adrenal pheochromocytomas. A rare manifestation of von Hippel-Lindau disease in childhood
    Jan M Langrehr
    Department for General, Visceral and Transplantation Surgery, Charite, Campus Virchow Clinic, 13353 Berlin, Germany
    J Pediatr Surg 42:1291-4. 2007
    ..This is the first report on the combination of a neuroendocrine pancreatic tumor with adrenal pheochromocytoma in a pediatric patient with von Hippel-Lindau (VHL) disease...
  18. ncbi request reprint Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway
    Eva Göncz
    Endokrinologie, Diabetes, und Stoffwechsel Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Endocrinology 149:1618-26. 2008
    ..As a physiological inhibitor of glucagon secretion, OXA may have a therapeutic potential to reduce hyperglucagonemia in type 2 diabetes...
  19. ncbi request reprint Characterization of somatostatin receptor subtype-specific regulation of insulin and glucagon secretion: an in vitro study on isolated human pancreatic islets
    Vandana Singh
    Medizinische Klinik m S Hepatologie, Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    J Clin Endocrinol Metab 92:673-80. 2007
    ..Human pancreatic A- and B-cells express SSTR1-3 and SSTR5; however, their contribution to the regulation of glucagon and insulin secretion is not well known...
  20. doi request reprint Selective loss of somatostatin receptor 2 in octreotide-resistant growth hormone-secreting adenomas
    Ursula Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Endokrinologie, Diabetes, und Stoffwechsel, Med Klinik m S Hepatologie und Gastroenterologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, D 13353 Berlin, Germany
    J Clin Endocrinol Metab 93:1203-10. 2008
    ..Hence, we investigated the immunocytochemical expression of sst in a large group of somatotroph tumors...
  21. ncbi request reprint Stress echocardiography for risk stratification of asymptomatic patients with type 2 diabetes mellitus
    Suzanne Fateh-Moghadam
    Medizinische Klinik mit Schwerpunkt Kardiologie, Universitätsklinik Charité Campus Virchow, Humboldt Universität zu Berlin und Freie Universität Berlin, Germany
    Int J Cardiol 131:288-90. 2009
    ..The purpose of this study was to assess stressechocardiography (SE) for risk stratification of asymptomatic type 2 diabetic patients (DM2) without known coronary artery disease CAD...
  22. ncbi request reprint Platelet degranulation is associated with progression of intima-media thickness of the common carotid artery in patients with diabetes mellitus type 2
    Suzanne Fateh-Moghadam
    Medizinische Klinik III, Universitatsklinikum Tubingen, Otfried Muller Strasse 10, D 72076 Tubingen, Germany
    Arterioscler Thromb Vasc Biol 25:1299-303. 2005
    ..Platelets play a key role in atherogenesis and thromboembolic complications in patients with type 2 diabetes...
  23. ncbi request reprint Surgical strategies and predictors of outcome for malignant neuroendocrine tumors of the pancreas
    Marcus Bahra
    General, Visceral and Transplantation Surgery Clinic, Charite, Campus Virchow Hospital, Humboldt University, Berlin, Germany
    J Gastroenterol Hepatol 22:930-5. 2007
    ..The aim of this study was to retrospectively review all patients who underwent pancreatic resection for malignant neuroendocrine tumor of the pancreas at the one department from 1989 to 2003...
  24. ncbi request reprint Transient receptor potential channel TRPM8 agonists stimulate calcium influx and neurotensin secretion in neuroendocrine tumor cells
    Stefan Mergler
    Department of Internal Medicine, Division of Hepatology and Gastroenterology, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Neuroendocrinology 85:81-92. 2007
    ..The regulation of NT secretion in NETs by TRPM8 may have a potential clinical implication in diagnosis or therapy...
  25. ncbi request reprint Survival and clinical outcome of patients with neuroendocrine tumors of the gastroenteropancreatic tract in a german referral center
    Ulrich Frank Pape
    Department of Internal Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Medical Faculty of the Humboldt University, Berlin, Germany
    Ann N Y Acad Sci 1014:222-33. 2004
    ..7% of successfully resected patients. Palliative medical treatment, either with chemotherapy (i.e., especially for foregut NETs) or biotherapy (especially for midgut NETs), was only moderately effective for both therapeutic regimens...
  26. ncbi request reprint Hepatitis-C patients have reduced growth hormone (GH) secretion which improves during long-term therapy with pegylated interferon-alpha
    Ursula Plockinger
    Interdisziplinäres Stoffwechsel Centrum, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
    Am J Gastroenterol 102:2724-31. 2007
    ..We therefore investigated prospectively basal and stimulated pituitary hormone secretion in 21 patients with chronic hepatitis C virus (HCV) infection before and during antiviral therapy...
  27. ncbi request reprint Chronic kidney disease in adolescent and adult patients with phenylketonuria
    Julia B Hennermann
    Department of Pediatric Endocrinology, Gastroenterology and Metabolic Diseases, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    J Inherit Metab Dis 36:747-56. 2013
    ..The effect of a long-term PKU diet on renal function and blood pressure has not been investigated yet...
  28. doi request reprint Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemia
    Theo D Kim
    Clinic for Hematology and Oncology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Thyroid 20:1209-14. 2010
    ..Thyroid dysfunction is a well-known adverse effect of first-generation tyrosine kinase inhibitors (TKIs), like sunitinib. The aim of this study was to investigate the effect of second-generation TKIs on thyroid function...