M Pirlich

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Loss of body cell mass in Cushing's syndrome: effect of treatment
    Matthias Pirlich
    Medizinische Klinik und Poliklinik, Abteilung Gastroenterologie, Universitatsklinikum Charite, Humboldt Universität zu Berlin D 10098, Germany
    J Clin Endocrinol Metab 87:1078-84. 2002
  2. ncbi Role of intestinal function in cachexia
    Matthias Pirlich
    Medizinische Klinik, Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Curr Opin Clin Nutr Metab Care 9:603-6. 2006
  3. ncbi [Malnutrition in liver cirrhosis: impact of protein rich oral diet]
    M Pirlich
    Klinik fur Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin
    Z Gastroenterol 44:344-5. 2006
  4. ncbi Prevalence of malnutrition in hospitalized medical patients: impact of underlying disease
    Matthias Pirlich
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin, Berlin, Deutschland
    Dig Dis 21:245-51. 2003
  5. ncbi The German hospital malnutrition study
    Matthias Pirlich
    Medizinische Klinik Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, D 10098 Berlin, Germany
    Clin Nutr 25:563-72. 2006
  6. ncbi Social risk factors for hospital malnutrition
    Matthias Pirlich
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin, Berlin, Germany
    Nutrition 21:295-300. 2005
  7. doi Cost-effectiveness of a 3-month intervention with oral nutritional supplements in disease-related malnutrition: a randomised controlled pilot study
    K Norman
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine, Berlin, Germany
    Eur J Clin Nutr 65:735-42. 2011
  8. ncbi Improved assessment of body cell mass by segmental bioimpedance analysis in malnourished subjects and acromegaly
    M Pirlich
    Medizinische Klinik und Poliklinik, Abteilung Gastroenterologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin, Germany
    Clin Nutr 22:167-74. 2003
  9. doi Increased intestinal permeability in malnourished patients with liver cirrhosis
    K Norman
    Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie einschl Arbeitsbereich Ernährungsmedizin, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Eur J Clin Nutr 66:1116-9. 2012
  10. ncbi Nutrition in the elderly
    M Pirlich
    , Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Schumannstrasse 20/21, D-10117 Berlin, Germany
    Best Pract Res Clin Gastroenterol 15:869-84. 2001

Collaborators

Detail Information

Publications48

  1. ncbi Loss of body cell mass in Cushing's syndrome: effect of treatment
    Matthias Pirlich
    Medizinische Klinik und Poliklinik, Abteilung Gastroenterologie, Universitatsklinikum Charite, Humboldt Universität zu Berlin D 10098, Germany
    J Clin Endocrinol Metab 87:1078-84. 2002
    ..The second interesting finding is that in the early recovery after successful treatment of hypercortisolism patients lose body fat without gaining BCM or muscle mass...
  2. ncbi Role of intestinal function in cachexia
    Matthias Pirlich
    Medizinische Klinik, Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Curr Opin Clin Nutr Metab Care 9:603-6. 2006
    ..This article reviews recent research into the role of the gut barrier in the pathogenesis of inflammation and cachexia with special emphasis on two potentially catabolic diseases: liver cirrhosis and chronic heart failure...
  3. ncbi [Malnutrition in liver cirrhosis: impact of protein rich oral diet]
    M Pirlich
    Klinik fur Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin
    Z Gastroenterol 44:344-5. 2006
  4. ncbi Prevalence of malnutrition in hospitalized medical patients: impact of underlying disease
    Matthias Pirlich
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin, Berlin, Deutschland
    Dig Dis 21:245-51. 2003
    ..Malnutrition is common among hospitalized patients. We investigated whether certain diseases predispose more frequently for malnutrition than others...
  5. ncbi The German hospital malnutrition study
    Matthias Pirlich
    Medizinische Klinik Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, D 10098 Berlin, Germany
    Clin Nutr 25:563-72. 2006
    ..Malnutrition is frequently observed in chronic and severe diseases and associated with impaired outcome. In Germany general data on prevalence and impact of hospital malnutrition are missing...
  6. ncbi Social risk factors for hospital malnutrition
    Matthias Pirlich
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin, Berlin, Germany
    Nutrition 21:295-300. 2005
    ..Disease severity is considered an important risk factor for malnutrition in hospitalized patients. We investigated the effect of social factors and disease parameters on the development of malnutrition...
  7. doi Cost-effectiveness of a 3-month intervention with oral nutritional supplements in disease-related malnutrition: a randomised controlled pilot study
    K Norman
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine, Berlin, Germany
    Eur J Clin Nutr 65:735-42. 2011
    ..We investigated whether post-hospital supplementation with ONS is cost-effective according to international benchmarks in malnourished patients...
  8. ncbi Improved assessment of body cell mass by segmental bioimpedance analysis in malnourished subjects and acromegaly
    M Pirlich
    Medizinische Klinik und Poliklinik, Abteilung Gastroenterologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin, Germany
    Clin Nutr 22:167-74. 2003
    ..Estimation of body cell mass (BCM) has been regarded valuable for the assessment of malnutrition...
  9. doi Increased intestinal permeability in malnourished patients with liver cirrhosis
    K Norman
    Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie einschl Arbeitsbereich Ernährungsmedizin, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Eur J Clin Nutr 66:1116-9. 2012
    ..The objective of this study is to investigate whether malnutrition is associated with increased gastrointestinal permeability in liver cirrhosis reflected by altered urinary excretion of non-metabolizable sugar probes...
  10. ncbi Nutrition in the elderly
    M Pirlich
    , Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Schumannstrasse 20/21, D-10117 Berlin, Germany
    Best Pract Res Clin Gastroenterol 15:869-84. 2001
    ..An improvement in the nutritional status can be achieved by simple methods such as the preparation of an adequate diet, hand feeding, additional sip feeding or enteral nutrition...
  11. ncbi Is bioelectrical impedance vector analysis of value in the elderly with malnutrition and impaired functionality?
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 23:564-9. 2007
    ..We therefore evaluated the use of bioelectrical impedance vector analysis in elderly nursing home residents...
  12. ncbi Malnutrition affects quality of life in gastroenterology patients
    Kristina Norman
    Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charité Universitätsmedizin Berlin Campus Mitte, Germany
    World J Gastroenterol 12:3380-5. 2006
    ..To investigate the association between malnutrition and quality of life in patients with benign gastrointestinal disease...
  13. doi Effects of food fortification on nutritional and functional status in frail elderly nursing home residents at risk of malnutrition
    Christine Smoliner
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 24:1139-44. 2008
    ..In this study we evaluated the effect of a 12-wk nutritional intervention with fortified food on nutritional and functional status in nursing home residents at risk of malnutrition...
  14. ncbi Three month intervention with protein and energy rich supplements improve muscle function and quality of life in malnourished patients with non-neoplastic gastrointestinal disease--a randomized controlled trial
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, 10098 Berlin, Germany
    Clin Nutr 27:48-56. 2008
    ..Malnutrition is a common problem in patients with digestive disease and is associated with impaired outcome...
  15. ncbi The Subjective Global Assessment reliably identifies malnutrition-related muscle dysfunction
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, 10098 Berlin, Germany
    Clin Nutr 24:143-50. 2005
    ..Muscle dysfunction is a common finding in malnourished patients and is associated with poor outcome. We investigated whether the Subjective Global Assessment (SGA) is a valuable tool for identifying malnutrition-related muscle dysfunction...
  16. ncbi Prognostic impact of disease-related malnutrition
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Nutr 27:5-15. 2008
    ....
  17. doi [Protein catabolism and malnutrition in liver cirrhosis - impact of oral nutritional therapy]
    K Norman
    Klinik fur Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin
    Z Gastroenterol 48:763-70. 2010
    ....
  18. doi Nutritional status as marker for disease activity and severity predicting mortality in patients with systemic sclerosis
    Lijana Krause
    Department of Rheumatology and Clinical Immunology, Charite Universitatsmedizin Berlin, Germany
    Ann Rheum Dis 69:1951-7. 2010
    ..To assess and analyse nutritional status in patients with systemic sclerosis (SSc) and identify possible associations with clinical symptoms and its prognostic value...
  19. ncbi Effects of creatine supplementation on nutritional status, muscle function and quality of life in patients with colorectal cancer--a double blind randomised controlled trial
    Kristina Norman
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite, Universitatsmedizin Berlin, 10098 Berlin
    Clin Nutr 25:596-605. 2006
    ..Since creatine supplementation has shown promising results in various diseases, we investigated the effects of creatine on nutritional status in patients with colorectal cancer undergoing chemotherapy...
  20. ncbi [Does coffee protect the liver?]
    C Smoliner
    Med Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Campus Mitte
    Z Gastroenterol 45:87-8. 2007
  21. ncbi Nutritional assessment and management in hospitalised patients: implication for DRG-based reimbursement and health care quality
    J Ockenga
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Clin Nutr 24:913-9. 2005
    ..The primary aim of this study was to evaluate the economic effect of a nutritional screening procedure on the identification and coding of malnutrition in the G-DRG system...
  22. doi Determinants of hand grip strength, knee extension strength and functional status in cancer patients
    Kristina Norman
    Charité Universitätsmedizin Berlin Campus Mitte, Dept of Gastroenterology, Germany
    Clin Nutr 29:586-91. 2010
    ..Decreased functionality and muscle weakness are prominent features in cancer patients. We investigated determinants of muscle function assessed by hand grip and knee extension strength as well as functional status in cancer patients...
  23. ncbi Manifestation of thyrotoxic periodic paralysis in two patients with adrenal adenomas and hyperandrogenaemia
    Henrik Biering
    Clinic for Internal Medicine, Gastroenterology, Hepatology and Endocrinology, University Hospital Charite, Humboldt University, Berlin, Germany
    Horm Res 59:301-4. 2003
    ..It may be of interest to focus not only on thyroid dysbalances in patients with TTP but also to investigate other hormonal disturbances...
  24. ncbi Disease-related malnutrition but not underweight by BMI is reflected by disturbed electric tissue properties in the bioelectrical impedance vector analysis
    Kristina Norman
    Charite Universitatsmedizin, Klinik fur Gastroenterologie, Hepatologie und Endokrinologie, Chariteplatz 1, Berlin 10117, Germany
    Br J Nutr 100:590-5. 2008
    ..These disturbances are not seen in underweight according to BMI. Bioelectrical impedance vector analysis appears to be an attractive tool to identify disease-related malnutrition and to monitor nutritional intervention...
  25. ncbi ["Malnutrition in the hospital": age as a special risk factor]
    Tatjana Schütz
    Pflege Z 59:778-9. 2006
  26. ncbi Malnutrition and impaired muscle strength in patients with Crohn's disease and ulcerative colitis in remission
    Luzia Valentini
    Department of Gastroenterology, Hepatology and Endocrinology, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 24:694-702. 2008
    ..In addition, possible effects of gender, malnutrition, inflammation, and previous prednisolone therapy were investigated...
  27. doi Differences of energy expenditure and physical activity patterns in subjects with various degrees of obesity
    Ulf Elbelt
    Department of Medicine, Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Nutr 29:766-72. 2010
    ....
  28. doi Cutoff percentiles of bioelectrical phase angle predict functionality, quality of life, and mortality in patients with cancer
    Kristina Norman
    Department of Gastroenterology, Charite Universitatsmedizin Berlin, Germany
    Am J Clin Nutr 92:612-9. 2010
    ..The bioelectrical phase angle has shown predictive potential in various diseases, but general cutoffs are lacking in the clinical setting...
  29. doi Hand grip strength: outcome predictor and marker of nutritional status
    Kristina Norman
    Department of Gastroenterology, Hepatology and Endocrinology, Charite University Medicine Berlin, Berlin, Germany
    Clin Nutr 30:135-42. 2011
    ..This review outlines the prognostic relevance of grip strength in various clinical and epidemiologic settings and investigates its suitability as marker of nutritional status in cross-sectional as well as intervention studies...
  30. doi Malnutrition and depression in the institutionalised elderly
    Christine Smoliner
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, Germany
    Br J Nutr 102:1663-7. 2009
    ..Further studies are needed to identify the direction of this relationship and to assess the effect of depression treatment on nutritional and functional status as well as on QoL...
  31. pmc Severe weight loss caused by chewing gum
    Juergen Bauditz
    Department of Gastroenterology, Hepatology, and Endocrinology, Charite Universitatsmedizin, 10117 Berlin, Germany
    BMJ 336:96-7. 2008
  32. ncbi [Enteral nutrition]
    M Pirlich
    Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Germany
    Internist (Berl) 47:405-19; quiz 420-21. 2006
    ..e. specific amino acids, nucleotides or fatty acids to improve the immune function. These modified diets are used for specific indications which are highlighted in this article...
  33. ncbi Assessment of suspected insulinoma by 48-hour fasting test: a retrospective monocentric study of 23 cases
    M Quinkler
    Clinical Endocrinology, Internal Medicine Center for Gastroenterology, Hepatology, and Endocrinology, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Horm Metab Res 39:507-10. 2007
    ..The aim of our study was to evaluate retrospectively the percentage of positive 48-hour fasting tests in a large series of patients with insulinoma...
  34. ncbi Introductory to the ESPEN Guidelines on Enteral Nutrition: Terminology, definitions and general topics
    H Lochs
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Germany
    Clin Nutr 25:180-6. 2006
    ..Additionally answers to more general questions, which might be important in most indications are dealt with, i.e. use of fibre containing and diabetes formulae...
  35. doi Bioimpedance vector analysis as a measure of muscle function
    Kristina Norman
    Charité Universitätsmedizin Berlin Campus Mitte, Department of Gastroenterology, Berlin, Germany
    Clin Nutr 28:78-82. 2009
    ..This study investigated the association between resistance and reactance normalised for height (R/H and Xc/H), and muscle function as assessed by hand grip strength...
  36. ncbi Elevated transaminases during medical treatment of acromegaly: a review of the German pegvisomant surveillance experience and a report of a patient with histologically proven chronic mild active hepatitis
    H Biering
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Germany
    Eur J Endocrinol 154:213-20. 2006
    ....
  37. ncbi Weight gain after transjugular intrahepatic portosystemic shunt is associated with improvement in body composition in malnourished patients with cirrhosis and hypermetabolism
    Mathias Plauth
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Hepatol 40:228-33. 2004
    ..To search for changes in body composition and energy metabolism associated with the repeatedly observed weight gain of cirrhotic patients after portosystemic shunting...
  38. doi Association between intestinal tight junction permeability and whole-body electrical resistance in healthy individuals: a hypothesis
    Luzia Valentini
    Department Gastroenterology, Hepatology and Endocrinology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 25:706-14. 2009
    ..The present report deals with the coincidentally observed associations between permeability results and electrical raw values of BIA and their subsequent reproduction in a larger group of individuals...
  39. ncbi [Tumour anorexia--tumour cachexia in case of gastrointestinal tumours: standards and visions]
    J Ockenga
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Humboldt Universitat, Charite, Berlin, Germany
    Z Gastroenterol 40:929-36. 2002
    ..An algorithm of the current treatment strategies is given. In addition, we discuss new anabolic and anticatabolic agents (e.g. eicosapentanoic acid) and the results from first clinical trials...
  40. doi Gastrointestinal tract in liver disease: which organ is sick?
    Kristina Norman
    Medizinische Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Charite Universitatsmedizin Berlin, CCM, Chariteplatz 1, Berlin, Germany
    Curr Opin Clin Nutr Metab Care 11:613-9. 2008
    ..This article gives an overview of the several morphological and functional alterations in the gastrointestinal tract that occur in liver disease and their systemic impact...
  41. doi Hepatic 11beta-HSD1 mRNA expression in fatty liver and nonalcoholic steatohepatitis
    Sarah Konopelska
    Internal Medicine, Center for Gastroenterology, Hepatology, and Endocrinology, Charite Campus Mitte, Charite University Medicine Berlin, Berlin, Germany
    Clin Endocrinol (Oxf) 70:554-60. 2009
    ..Nonalcoholic fatty liver disease represents the hepatic manifestation of the metabolic syndrome. Nonalcoholic steatohepatitis (NASH) is the progressive form of liver injury. The pathophysiology that leads to NASH is not well understood...
  42. ncbi [What is malnutrition?]
    Matthias Pirlich
    Wien Klin Wochenschr 116:575-8. 2004
  43. ncbi Increased length of hospital stay in underweight and overweight patients at hospital admission: a controlled population study
    Ursula G Kyle
    Clinical Nutrition, Geneva University Hospital, 1211 Geneva, Switzerland
    Clin Nutr 24:133-42. 2005
    ....
  44. ncbi Does nutritional risk, as assessed by Nutritional Risk Index, increase during hospital stay? A multinational population-based study
    Ursula G Kyle
    Clinical Nutrition, Geneva University Hospital, Geneva, Switzerland
    Clin Nutr 24:516-24. 2005
    ..This prospective study compared the proportion of nutritional risk at hospital admission in three European countries and further evaluated nutritional risk at late versus early phase of hospitalization in one hospital...
  45. ncbi Is nutritional depletion by Nutritional Risk Index associated with increased length of hospital stay? A population-based study
    Ursula G Kyle
    Department of Clinical Nutrition, Geneva University Hospital, Geneva, Switzerland
    JPEN J Parenter Enteral Nutr 28:99-104. 2004
    ....
  46. ncbi Bioelectrical impedance analysis--part I: review of principles and methods
    Ursula G Kyle
    Geneva University Hospital, Switzerland
    Clin Nutr 23:1226-43. 2004
    ..ESPEN guidelines for the clinical use of BIA measurements are described in a paper to appear soon in Clinical Nutrition...
  47. ncbi Alterations in glucose metabolism associated with liver cirrhosis persist in the clinically stable long-term course after liver transplantation
    Uwe J F Tietge
    Department of Gastroenterology, Hepatology, and Endocrinology, Hannover Medical School, Hannover, Germany
    Liver Transpl 10:1030-40. 2004
    ..This finding was independent of the immunosuppressive medication. The peripheral insulin resistance in cirrhosis is characterized by a decrease in nonoxidative glucose disposal that is improved, but not normalized, after OLT...
  48. ncbi Bioelectrical impedance analysis-part II: utilization in clinical practice
    Ursula G Kyle
    Clinical Nutrition Unit, Geneva University Hospital, 1211 Geneva 14, Switzerland
    Clin Nutr 23:1430-53. 2004
    ..Further validation of BIA is necessary to understand the mechanisms for the changes observed in acute illness, altered fat/lean mass ratios, extreme heights and body shape abnormalities...