Christian Otte

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study
    Christian Otte
    Department of Psychiatry, Campus Benjamin Franklin, Charite University Medical Center, Berlin, Germany
    J Clin Psychiatry 73:610-5. 2012
  2. pmc Cognitive behavioral therapy in anxiety disorders: current state of the evidence
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Dialogues Clin Neurosci 13:413-21. 2011
  3. ncbi request reprint Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study
    Christian Otte
    Department of Psychiatry, University Medical Center, 20246 Hamburg Eppendorf, Germany
    J Clin Endocrinol Metab 95:2885-91. 2010
  4. doi request reprint Changes in cortisol secretion during antidepressive treatment and cognitive improvement in patients with major depression: a longitudinal study
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Psychoneuroendocrinology 37:685-92. 2012
  5. doi request reprint Cortisol has enhancing, rather than impairing effects on memory retrieval in PTSD
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Berlin, Germany
    Psychoneuroendocrinology 37:1048-56. 2012
  6. doi request reprint Hair testosterone and visuospatial memory in middle-aged men and women with and without depressive symptoms
    Lucia Dettenborn
    Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Psychoneuroendocrinology 38:2373-7. 2013
  7. doi request reprint Noradrenergic blockade and memory in patients with major depression and healthy participants
    Anja Kuffel
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Psychoneuroendocrinology 40:86-90. 2014
  8. doi request reprint Cortisol response to experimental pain in patients with chronic low back pain and patients with major depression
    Christoph Muhtz
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Pain Med 14:498-503. 2013
  9. pmc Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Psychoneuroendocrinology 34:1574-81. 2009
  10. doi request reprint Effects of noradrenergic stimulation on memory in patients with major depressive disorder
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Eschenallee 3, 14050 Berlin, Germany
    Stress 16:191-201. 2013

Collaborators

Detail Information

Publications18

  1. doi request reprint Statin use and risk of depression in patients with coronary heart disease: longitudinal data from the Heart and Soul Study
    Christian Otte
    Department of Psychiatry, Campus Benjamin Franklin, Charite University Medical Center, Berlin, Germany
    J Clin Psychiatry 73:610-5. 2012
    ..Statins are among the most commonly prescribed medications worldwide. Although their benefits for cardiovascular disease are well established, the effects of statins on depressive symptoms are unknown...
  2. pmc Cognitive behavioral therapy in anxiety disorders: current state of the evidence
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Dialogues Clin Neurosci 13:413-21. 2011
    ..In conclusion, CBT appears to be both efficacious and effective in the treatment of anxiety disorders, but more high-quality studies are needed to better estimate the magnitude of the effect...
  3. ncbi request reprint Glucocorticoid receptor gene, low-grade inflammation, and heart failure: the Heart and Soul study
    Christian Otte
    Department of Psychiatry, University Medical Center, 20246 Hamburg Eppendorf, Germany
    J Clin Endocrinol Metab 95:2885-91. 2010
    ..A common haplotype of the glucocorticoid receptor (GR) gene has been associated with increased susceptibility to coronary heart disease (CHD). Whether this haplotype predisposes to heart failure (HF) is unknown...
  4. doi request reprint Changes in cortisol secretion during antidepressive treatment and cognitive improvement in patients with major depression: a longitudinal study
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Psychoneuroendocrinology 37:685-92. 2012
    ..Here, we longitudinally examined if changes in cortisol secretion during treatment are associated with improvement of cognition...
  5. doi request reprint Cortisol has enhancing, rather than impairing effects on memory retrieval in PTSD
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Berlin, Germany
    Psychoneuroendocrinology 37:1048-56. 2012
    ..In healthy participants, administration of cortisol impairs declarative memory retrieval. Only a few studies have investigated these effects in PTSD yielding mixed results...
  6. doi request reprint Hair testosterone and visuospatial memory in middle-aged men and women with and without depressive symptoms
    Lucia Dettenborn
    Department of Medical Psychology, University Medical Center Hamburg Eppendorf, Hamburg, Germany Electronic address
    Psychoneuroendocrinology 38:2373-7. 2013
    ..We examined hair testosterone and its association with verbal and visuospatial memory in middle-aged men and women with and without major depression...
  7. doi request reprint Noradrenergic blockade and memory in patients with major depression and healthy participants
    Anja Kuffel
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Psychoneuroendocrinology 40:86-90. 2014
    ..In the current study, we further examined the role of noradrenaline on memory in MDD by administering clonidine that activates presynaptic α2 receptors and thereby globally suppresses the noradrenergic output...
  8. doi request reprint Cortisol response to experimental pain in patients with chronic low back pain and patients with major depression
    Christoph Muhtz
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Pain Med 14:498-503. 2013
    ..However, little is known about the effects of experimentally induced acute pain on cortisol secretion in patients with chronic pain and depression...
  9. pmc Glucocorticoid receptor gene and depression in patients with coronary heart disease: the Heart and Soul Study-2009 Curt Richter Award Winner
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Psychoneuroendocrinology 34:1574-81. 2009
    ..3-9.4, p=0.01). These associations persisted after adjusting for potentially confounding variables. A common GR haplotype was associated with depression in a gene-dosage dependent manner and might be a vulnerability factor for depression...
  10. doi request reprint Effects of noradrenergic stimulation on memory in patients with major depressive disorder
    Katja Wingenfeld
    Department of Psychiatry, Charite University Berlin, Campus Benjamin Franklin, Eschenallee 3, 14050 Berlin, Germany
    Stress 16:191-201. 2013
    ..The mechanism by which yohimbine leads to stronger memory consolidation in depressed patients compared with healthy controls remains to be elucidated...
  11. ncbi request reprint C-reactive protein, pre- and postdexamethasone cortisol levels in post-traumatic stress disorder
    Carsten Spitzer
    Carsten Spitzer, Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany, and Asklepios Fachklinikum Tiefenbrunn, Rosdorf, Germany
    Nord J Psychiatry 68:296-9. 2014
    ..However, a dysbalanced immune system with suppressed CRP might contribute to the elevated somatic comorbidity in PTSD. ..
  12. pmc Enhanced emotional empathy after mineralocorticoid receptor stimulation in women with borderline personality disorder and healthy women
    Katja Wingenfeld
    Department of Psychiatry and Psychotherapy, Charité University Medical School Berlin, Campus Benjamin Franklin, Berlin, Germany
    Neuropsychopharmacology 39:1799-804. 2014
    ..Stimulation of MR enhanced emotional empathy in healthy women and in BPD patients. Whether fludrocortisone might have a therapeutic role in psychotherapeutic processes, remains to be elucidated. ..
  13. doi request reprint Hydrocortisone impairs working memory in healthy humans, but not in patients with major depressive disorder
    Kirsten Terfehr
    Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Hamburg Eppendorf and Schön Klinik Hamburg Eilbek, Hamburg, Germany
    Psychopharmacology (Berl) 215:71-9. 2011
    ..The purpose of our study was to investigate whether the finding of missing effects of acute cortisol administration on memory performance in MDD is also seen when examining prefrontal-based working memory...
  14. doi request reprint Association of a common mineralocorticoid receptor gene polymorphism with salivary cortisol in healthy adults
    Christoph Muhtz
    Department of Psychiatry and Psychotherapy, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Psychoneuroendocrinology 36:298-301. 2011
    ..This polymorphism may contribute to the interindividual variability in stress responsiveness and might be involved in stress-related disorders...
  15. ncbi request reprint Cognitive impairment in major depression: association with salivary cortisol
    Kim Hinkelmann
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Biol Psychiatry 66:879-85. 2009
    ..Several studies have separately examined cortisol secretion and cognitive deficits in depression. However, only few studies have assessed their association in the same patients producing inconclusive results...
  16. ncbi request reprint Decreased hydrocortisone sensitivity of T cell function in multiple sclerosis-associated major depression
    Anja Fischer
    Institute for Neuroimmunology and Clinical Multiple Sclerosis Research, Center for Molecular Neurobiology, University Hospital Hamburg Eppendorf, Hamburg, Germany
    Psychoneuroendocrinology 37:1712-8. 2012
    ..To our knowledge, this study provides first evidence for altered steroid sensitivity of T cells from MS patients with comorbid MDD possibly due to MR dysregulation...
  17. pmc Incomplete remission in depression: role of psychiatric and somatic comorbidity
    Christian Otte
    Department of Psychiatry, University Medical Center Hamburg Eppendorf, Germany
    Dialogues Clin Neurosci 10:453-60. 2008
    ..These findings raise important research and treatment issues regarding the generalizability from randomized controlled trials that to exclude patients tend to exclude patients with comorbidity...
  18. pmc Association of a serotonin transporter polymorphism (5-HTTLPR) with depression, perceived stress, and norepinephrine in patients with coronary disease: the Heart and Soul Study
    Christian Otte
    Department of Psychiatry and Psychotherapy, University Medical Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Am J Psychiatry 164:1379-84. 2007
    ..Whether the short allele increases risk for depression associated with the stress of a chronic illness has not been established...