Alexander Nast

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Barriers to the prescription of systemic therapies for moderate-to-severe psoriasis--a multinational cross-sectional study
    A Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Arch Dermatol Res 305:899-907. 2013
  2. doi request reprint National and multinational guidelines in Europe: results from an online survey on awareness of different national and European psoriasis guidelines
    Alexander Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Germany
    Arch Dermatol Res 305:637-43. 2013
  3. doi request reprint Management of anticoagulation during dermatosurgical procedures in Germany - results from a cross-sectional study
    Alexander Nast
    Division of Evidence Based Medicine, Department of Dermatology, Venereology and Allergology, Charite University Medicine Berlin, Germany
    J Dtsch Dermatol Ges 11:52-9. 2013
  4. doi request reprint [Using new media for online consensus conferences and open external review of guidelines - results of two pilot studies]
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin
    Z Evid Fortbild Qual Gesundhwes 106:295-301. 2012
  5. doi request reprint Low prescription rate for systemic treatments in the management of severe psoriasis vulgaris and psoriatic arthritis in dermatological practices in Berlin and Brandenburg, Germany: results from a patient registry
    A Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Eur Acad Dermatol Venereol 22:1337-42. 2008
  6. doi request reprint [S3-guidelines for the treatment of psoriasis vulgaris--methods report]
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    J Dtsch Dermatol Ges 9:e64-84. 2011
  7. doi request reprint Evidence-based (S3) guideline for the treatment of psoriasis vulgaris - Update: "Therapeutic options" and "Efalizumab"
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin
    J Dtsch Dermatol Ges 8:65-6. 2010
  8. doi request reprint Three years after the publication of the German (S3) evidence based psoriasis guidelines--was it worth the effort?
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Deparment of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, Berlin
    J Dtsch Dermatol Ges 7:1044-7. 2009
  9. doi request reprint Do guidelines change the way we treat? Studying prescription behaviour among private practitioners before and after the publication of the German Psoriasis Guidelines
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, 10117 Berlin, Germany
    Arch Dermatol Res 301:553-9. 2009
  10. doi request reprint Translating psoriasis treatment guidelines into clinical practice - the need for educational interventions and strategies for broad dissemination
    Alexander Nast
    Division of Evidence Based Medicine, Klinik für Dermatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Eval Clin Pract 14:803-6. 2008

Detail Information

Publications25

  1. ncbi request reprint Barriers to the prescription of systemic therapies for moderate-to-severe psoriasis--a multinational cross-sectional study
    A Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Arch Dermatol Res 305:899-907. 2013
    ..Country specific analysis showed national differences in the perception of safety. The treatment barriers identified in this exploratory study should be confirmed in further health services research. ..
  2. doi request reprint National and multinational guidelines in Europe: results from an online survey on awareness of different national and European psoriasis guidelines
    Alexander Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Germany
    Arch Dermatol Res 305:637-43. 2013
    ..National guidelines can reach almost complete awareness within their respective countries. The original publication is still the most important dissemination tool for guidelines...
  3. doi request reprint Management of anticoagulation during dermatosurgical procedures in Germany - results from a cross-sectional study
    Alexander Nast
    Division of Evidence Based Medicine, Department of Dermatology, Venereology and Allergology, Charite University Medicine Berlin, Germany
    J Dtsch Dermatol Ges 11:52-9. 2013
    ..Treatment with antiplatelet drugs (APD) and vitamin K antagonists (VKA) can be a challenge during the management of dermatosurgical interventions...
  4. doi request reprint [Using new media for online consensus conferences and open external review of guidelines - results of two pilot studies]
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin
    Z Evid Fortbild Qual Gesundhwes 106:295-301. 2012
    ..After the review process, the comments were assessed by the editors and the original authors. The selected instrument provides a suitable means for online commenting of guidelines and facilitates the revision of the text...
  5. doi request reprint Low prescription rate for systemic treatments in the management of severe psoriasis vulgaris and psoriatic arthritis in dermatological practices in Berlin and Brandenburg, Germany: results from a patient registry
    A Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Eur Acad Dermatol Venereol 22:1337-42. 2008
    ..However, detailed data on prescription behaviour in Germany, especially with regard to the use of new treatment options (e.g. biologics) in private practices, are lacking...
  6. doi request reprint [S3-guidelines for the treatment of psoriasis vulgaris--methods report]
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    J Dtsch Dermatol Ges 9:e64-84. 2011
    ..This methods report summarizes the methodology used to update the German Psoriasis Guidelines...
  7. doi request reprint Evidence-based (S3) guideline for the treatment of psoriasis vulgaris - Update: "Therapeutic options" and "Efalizumab"
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin
    J Dtsch Dermatol Ges 8:65-6. 2010
    ..The guideline group has changed the guideline accordingly...
  8. doi request reprint Three years after the publication of the German (S3) evidence based psoriasis guidelines--was it worth the effort?
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Deparment of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, Berlin
    J Dtsch Dermatol Ges 7:1044-7. 2009
    ..The guidelines' discussion was continued even after its publication and in further publications from within the group a therapeutic algorithm, treatment goals and indicators for the quality of care have been developed...
  9. doi request reprint Do guidelines change the way we treat? Studying prescription behaviour among private practitioners before and after the publication of the German Psoriasis Guidelines
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, 10117 Berlin, Germany
    Arch Dermatol Res 301:553-9. 2009
    ..All but one participant considered the guidelines "useful" or "very useful". The results of the study show that guidelines can be an important tool for improving the quality of care provided to patients with psoriasis...
  10. doi request reprint Translating psoriasis treatment guidelines into clinical practice - the need for educational interventions and strategies for broad dissemination
    Alexander Nast
    Division of Evidence Based Medicine, Klinik für Dermatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Eval Clin Pract 14:803-6. 2008
    ..However, it is important to ensure that guidelines are: (1) developed in areas in which they are needed the most; and (2) translated effectively into everyday clinical practice...
  11. doi request reprint Online lectures for students in dermatology: a replacement for traditional teaching or a valuable addition?
    A Nast
    Division of Evidence Based Medicine in Dermatology, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Eur Acad Dermatol Venereol 23:1039-43. 2009
    ..We aimed to increase the percentage of students benefiting from our lectures during their 6-month principal training period in dermatology by making lectures available online...
  12. ncbi request reprint A critical appraisal of evidence-based guidelines for the treatment of psoriasis vulgaris: 'AGREE-ing' on a common base for European evidence-based psoriasis treatment guidelines
    A Nast
    Division of Evidence Based Medicine, Department of Dermatology, Charite Universitatsmedizin Berlin, Germany
    J Eur Acad Dermatol Venereol 23:782-7. 2009
    ....
  13. ncbi request reprint Evidence-based (S3) guidelines for the treatment of psoriasis vulgaris
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Germany
    J Dtsch Dermatol Ges 5:1-119. 2007
    ..The therapeutic recommendations were developed by an expert group and finalized during interdisciplinary consensus conferences...
  14. doi request reprint S3 - Guidelines on the treatment of psoriasis vulgaris (English version). Update
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Germany
    J Dtsch Dermatol Ges 10:S1-95. 2012
    ..The therapeutic recommendations were developed based on the results of a systematic literature search and were finalized during a consensus meeting using structured consensus methods (nominal group process)...
  15. doi request reprint Efficacy and durability of two hyaluronic acid-based fillers in the correction of nasolabial folds: results of a prospective, randomized, double-blind, actively controlled clinical pilot study
    Alexander Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Berlin, Germany
    Dermatol Surg 37:768-75. 2011
    ..This pilot study compared a monophasic hyaluronic acid dermal filler with a biphasic filler for the correction of nasolabial folds...
  16. doi request reprint Which antipsoriatic drug has the fastest onset of action? Systematic review on the rapidity of the onset of action
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Department of Dermatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Invest Dermatol 133:1963-70. 2013
    ..Psoriasis trials should consider including TOA as an additional outcome measure. ..
  17. doi request reprint E-learning in the dermatological education at the Charité: evaluation of the last three years
    Tilman Lüdert
    Division of Evidence Based Medicine in Dermatology, Department of Dermatology, Venerology, and Allergology, Charite Universitatsmedizin Berlin, Germany
    J Dtsch Dermatol Ges 6:467-72. 2008
    ..DEJAVU offers an online archive of recorded lectures, lecture hand outs, structured learning modules, and case reports as well as online information about the courses/classes...
  18. pmc Study of perceptions of the extent to which guideline recommendations are binding: a survey of commonly used terminology
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Department of Dermatology, Venerology and Allergology, Charite Universitatsmedizin, Berlin
    Dtsch Arztebl Int 110:663-8. 2013
    ..In this study, doctors were asked in a survey about what they considered to be the level of obligation carried by various formulations that are commonly used in guidelines to recommend particular courses of action...
  19. ncbi request reprint [S3-Guidelines for the therapy of psoriasis vulgaris]
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin
    J Dtsch Dermatol Ges 4:S1-126. 2006
  20. doi request reprint Disclosure of potential conflicts of interest in dermatological guidelines in Germany - an analysis - status quo and quo vadis
    Stefanie Rosumeck
    Division of Evidence Based Medicine dEBM, Department of Dermatology, Charite University Medicine, Berlin Germany
    J Dtsch Dermatol Ges 9:297-304. 2011
    ..In order to ensure the reliability of clinical practice guidelines it is essential to consider potential conflicts of interest with regard to its development...
  21. doi request reprint Methodological standards in medical reporting
    Birte Sporbeck
    Division of Evidence Based Medicine dEBM, Department of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Germany
    J Dtsch Dermatol Ges 11:107-20. 2013
    ..In this CME article we present guidelines for reporting of randomized controlled trials (CONSORT), observational studies (STROBE) and systematic reviews and meta-analyses (PRISMA, MOOSE)...
  22. doi request reprint Can physician's self-estimates be used as a valid instrument to determine prescription frequencies of anti-psoriatic drugs? Comparison of the results of a cross-sectional study using self-estimates with actual prescription behavior documented in a cohort
    Alexander Nast
    Division of Evidence Based Medicine dEBM, Klinik fur Dermatologie, Charite Universitatsmedizin Berlin, Germany
    Pharmacoepidemiol Drug Saf 22:1154-8. 2013
    ..Self-estimates as a tool for health-care research on prescription frequencies need to be validated as a suitable method before it can be used widely...
  23. doi request reprint Acne treatment in the field: how guidelines and other sources can be included in daily practice
    Berthold Rzany
    Rzany and Hund, Kurfürstendamm 183, Berlin, D 10707, Germany
    J Eur Acad Dermatol Venereol 27:2-5. 2013
    ..Acne is a complex disease ranging from mild to very severe. Quality of life can be considerably affected although the impact on the quality of life does not necessarily correlate with the severity of the disease...
  24. doi request reprint [S2k-guideline for therapy of acne]
    Alexander Nast
    Division of Evidence Based Medicine, Klinik fur Dermatologie, Venerologie und Allergologie, Charite Universitatsmedizin Berlin, Berlin
    J Dtsch Dermatol Ges 8:s1-59. 2010
    ..For maintenance treatment: topical retinoid or its combination with BPO. Particular attention should be paid to compliance and quality of life. Additional treatment options are discussed in the main body of the text...
  25. doi request reprint Hand augmentation with stabilized hyaluronic acid (Macrolane VRF20 and Restylane Vital, Restylane Vital Light)
    Vanessa Hartmann
    Division of Evidence Based Medicine dEBM, Department of Dermatology, Venereology and Allergy, Charite University Medicine Berlin, Berlin, Germany
    J Dtsch Dermatol Ges 8:41-4. 2010
    ..Significant adverse events did not occur. After injection of the hyaluronic acid fillers, the appearance of the back of the hands was improved. Both patients were very satisfied with the result...