Stanislao Morgera

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Intermittent high-permeability hemofiltration modulates inflammatory response in septic patients with multiorgan failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Nephron Clin Pract 94:c75-80. 2003
  2. ncbi request reprint Regional citrate anticoagulation in continuous hemodialysis--acid-base and electrolyte balance at an increased dose of dialysis
    Stanislao Morgera
    Department of Nephrology, University Hospital Charité Campus Mitte, Berlin, Germany
    Nephron Clin Pract 101:c211-9. 2005
  3. doi request reprint Long-term outcomes after acute kidney injury
    Stanislao Morgera
    Department of Nephrology, University Hospital Charite, Campus Mitte, Berlin, Germany
    Crit Care Med 36:S193-7. 2008
  4. ncbi request reprint A simple, safe and effective citrate anticoagulation protocol for the genius dialysis system in acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Nephron Clin Pract 98:c35-40. 2004
  5. ncbi request reprint Metabolic complications during regional citrate anticoagulation in continuous venovenous hemodialysis: single-center experience
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Nephron Clin Pract 97:c131-6. 2004
  6. pmc Novel renal replacement strategies for the elimination of serum free light chains in patients with kappa light chain nephropathy
    L Kleeberg
    Department of Hematology and Oncology, Charite Universitatsmedizin Berlin, Germany
    Eur J Med Res 14:47-54. 2009
  7. ncbi request reprint Renal replacement therapy with high-cutoff hemofilters: Impact of convection and diffusion on cytokine clearances and protein status
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Am J Kidney Dis 43:444-53. 2004
  8. ncbi request reprint Combined ETA/ETB receptor blockade of human peritoneal mesothelial cells inhibits collagen I RNA synthesis
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Kidney Int 64:2033-40. 2003
  9. ncbi request reprint High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Schumannstrasse 20 21, D 10098 Berlin, Germany
    Nephrol Dial Transplant 18:2570-6. 2003
  10. ncbi request reprint Intermittent high permeability hemofiltration in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Schumannstrasse 20 21, 10098, Berlin, Germany
    Intensive Care Med 29:1989-95. 2003

Detail Information

Publications43

  1. ncbi request reprint Intermittent high-permeability hemofiltration modulates inflammatory response in septic patients with multiorgan failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Nephron Clin Pract 94:c75-80. 2003
    ..The present study examines whether intermittent high-permeability hemofiltration has an immunomodulatory effect on polymorphonuclear leukocytes and mononuclear cells...
  2. ncbi request reprint Regional citrate anticoagulation in continuous hemodialysis--acid-base and electrolyte balance at an increased dose of dialysis
    Stanislao Morgera
    Department of Nephrology, University Hospital Charité Campus Mitte, Berlin, Germany
    Nephron Clin Pract 101:c211-9. 2005
    ..This study aimed at establishing a citrate anticoagulation protocol designed for a dialysate flow rate of about 2 l/h...
  3. doi request reprint Long-term outcomes after acute kidney injury
    Stanislao Morgera
    Department of Nephrology, University Hospital Charite, Campus Mitte, Berlin, Germany
    Crit Care Med 36:S193-7. 2008
    ..There is no doubt that aggressive intensive care unit treatment is justified in these patients, irrespective of the health costs...
  4. ncbi request reprint A simple, safe and effective citrate anticoagulation protocol for the genius dialysis system in acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Nephron Clin Pract 98:c35-40. 2004
    ..A standard heparin anticoagulation protocol served as control...
  5. ncbi request reprint Metabolic complications during regional citrate anticoagulation in continuous venovenous hemodialysis: single-center experience
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Nephron Clin Pract 97:c131-6. 2004
    ....
  6. pmc Novel renal replacement strategies for the elimination of serum free light chains in patients with kappa light chain nephropathy
    L Kleeberg
    Department of Hematology and Oncology, Charite Universitatsmedizin Berlin, Germany
    Eur J Med Res 14:47-54. 2009
    ..Hemodiafiltration and to lesser extend also hemodialysis with the HCO 1100 hemofilter are able to eliminate substantial amounts of sFLC kappa in MM patients...
  7. ncbi request reprint Renal replacement therapy with high-cutoff hemofilters: Impact of convection and diffusion on cytokine clearances and protein status
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Am J Kidney Dis 43:444-53. 2004
    ..This study compares diffusive versus convective high-cutoff renal replacement therapy (RRT) in terms of cytokine clearance rates and effects on plasma protein levels...
  8. ncbi request reprint Combined ETA/ETB receptor blockade of human peritoneal mesothelial cells inhibits collagen I RNA synthesis
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Kidney Int 64:2033-40. 2003
    ..We studied osmolarity and physical stress-induced effects on collagen I RNA synthesis in human peritoneal mesothelial cells (HPMCs) and focused on endothelin as a possible mediator...
  9. ncbi request reprint High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Schumannstrasse 20 21, D 10098 Berlin, Germany
    Nephrol Dial Transplant 18:2570-6. 2003
    ..The present study examines whether HP-HF has an impact on peripheral blood mononuclear cell (PBMC) proliferation and whether ultrafiltrate can alter PBMC function in isolates from healthy volunteers...
  10. ncbi request reprint Intermittent high permeability hemofiltration in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Schumannstrasse 20 21, 10098, Berlin, Germany
    Intensive Care Med 29:1989-95. 2003
    ..In addition, the clearance capacity for interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha) is analyzed...
  11. ncbi request reprint Long-term outcomes in acute renal failure patients treated with continuous renal replacement therapies
    Stanislao Morgera
    Department of Nephrology and Institute for Medical Biometrics, Charite, Germany
    Am J Kidney Dis 40:275-9. 2002
    ..Limited health care budgets have raised the issue of how much therapy should be dedicated to critically ill patients with multiorgan and acute renal failure (ARF). No data are available on patients with ARF after hospital discharge...
  12. ncbi request reprint TNF-alpha elimination with high cut-off haemofilters: a feasible clinical modality for septic patients?
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Nephrol Dial Transplant 18:1361-9. 2003
    ..We analysed the cytokine elimination capacity of a newly developed polyflux high cut-off haemofilter. Different renal replacement therapies are compared and tested for their clinical feasibility...
  13. doi request reprint A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acid-base status
    Stanislao Morgera
    Departmentsof Nephrology, University Hospital Charité Campus Mitte, Berlin, Germany
    Crit Care Med 37:2018-24. 2009
    ..In this article, we provide a safe and an easy-to-handle citrate anticoagulation protocol with variable treatment doses and excellent control of the acid-base status...
  14. ncbi request reprint Glucose-mediated transforming growth factor-beta1 release in human mesothelial cells is endothelin independent
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    J Cardiovasc Pharmacol 44:S216-8. 2004
    ..In conclusion, HPMC TGF-beta1 release by glucose and mechanical stress seems not to be related to the activity of the peritoneal endothelin system - at least in our in vitro model...
  15. ncbi request reprint Pilot study on the effects of high cutoff hemofiltration on the need for norepinephrine in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Crit Care Med 34:2099-104. 2006
    ..High cutoff hemofilters are characterized by an increased effective pore size designed to facilitate the elimination of inflammatory mediators in sepsis. Clinical data on this new renal replacement modality are lacking...
  16. ncbi request reprint Protracted bleeding after hirudin anticoagulation for cardiac surgery in a patient with HIT II and chronic renal failure
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Charite University Hospital Berlin, Campus Mitte, Berlin, Germany
    Artif Organs 29:507-10. 2005
    ....
  17. ncbi request reprint Iloprost for additional anticoagulation in continuous renal replacement therapy--a pilot study
    Jurgen Birnbaum
    Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Charité Virchow Klinikum, Charite University Medicine, Berlin, Germany
    Ren Fail 29:271-7. 2007
    ..The aim of this pilot study was to compare the effect of heparin anticoagulation with and without iloprost administration during continuous renal replacement therapy (CRRT) in critically ill patients...
  18. ncbi request reprint Intermittent hirudin versus continuous heparin for anticoagulation in continuous renal replacement therapy
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Berlin, Germany
    Ren Fail 26:297-303. 2004
    ..Aim of this prospective-controlled pilot study was to compare the efficacy and safety of intermittent hirudin and continuous heparin for anticoagulation during CRRT in critically ill patients...
  19. ncbi request reprint The use of contrast-enhanced US in renal transplant: first results and potential clinical benefit
    Thomas Fischer
    Department of Radiology, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Eur Radiol 15:E109-16. 2005
    ....
  20. ncbi request reprint Use of fondaparinux (ARIXTRA) in a dialysis patient with symptomatic heparin-induced thrombocytopaenia type II
    Michael Haase
    Department of Nephrology, University and Teaching Hospitals, Humboldt Univeristy of Berlin, Germany
    Nephrol Dial Transplant 20:444-6. 2005
  21. doi request reprint Does endothelin B receptor deficiency ameliorate the induction of peritoneal fibrosis in experimental peritoneal dialysis?
    Philipp Kalk
    Department of Pharmacology and Toxicology, Center for Cardiovascular Research, Charite, Berlin, Germany
    Nephrol Dial Transplant 25:1474-8. 2010
    ..Thus, our study aimed at elucidating the impact of the endothelin B (ETB) receptor on peritoneal membrane thickening by means of an ETB-deficient rat model (ETB(-)(/)(-)) in experimental PD...
  22. doi request reprint Rosuvastatin is additive to high-dose candesartan in slowing progression of experimental mesangioproliferative glomerulosclerosis
    Stephanie Kramer
    Dept of Nephrology, Charite Universitatsmedizin Berlin, Campus Mitte, Humboldt Univ, Chariteplatz 1, D 10098 Berlin, Germany
    Am J Physiol Renal Physiol 294:F801-11. 2008
    ..The results suggest that rosuvastatin and an AT(1) blocker independently interfere with separate key pathways involved in the progression of chronic mesangioproliferative GS...
  23. ncbi request reprint A systematic approach to managing pregnant dialysis patients--the importance of an intensified haemodiafiltration protocol
    Michael Haase
    Departments of Nephrology, Charité University Hospital CCM, Berlin, Germany
    Nephrol Dial Transplant 20:2537-42. 2005
    ..Here, we report the successful multidisciplinary management of five consecutive pregnant dialysis patients...
  24. ncbi request reprint Improved diagnosis of early kidney allograft dysfunction by ultrasound with echo enhancer--a new method for the diagnosis of renal perfusion
    Thomas Fischer
    Institut für Radiologie Charité, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Nephrol Dial Transplant 21:2921-9. 2006
    ..We, therefore, performed a prospective study to compare the value of ultrasound contrast media (USCM) with conventional US in the diagnosis of early allograft dysfunction...
  25. ncbi request reprint Quality of life of living kidney donors in Germany: a survey with the Validated Short Form-36 and Giessen Subjective Complaints List-24 questionnaires
    Markus Giessing
    Department of Urology, Charite University Hospital, Campus Mitte, Berlin, Germany
    Transplantation 78:864-72. 2004
    ..Most studies evaluating the impact of kidney donation on donors' quality of life (QOL) have limitations such as small cohort size, unmatched references, use of nonstandardized and nonvalidated questionnaires, or low response rates...
  26. doi request reprint Regional citrate anticoagulation for high volume continuous venovenous hemodialysis in surgical patients with high bleeding risk
    Robert Kalb
    Department of Anaesthesiology, Duesseldorf University Hospital, Duesseldorf, Germany
    Ther Apher Dial 17:202-12. 2013
    ..Therefore, citrate anticoagulated continuous venovenous hemodialysis is a useful treatment option for patients with acute kidney injury requiring high dialysis doses and at risk of bleeding...
  27. ncbi request reprint Low-dose prostacyclin preserves renal function in high-risk patients after coronary bypass surgery
    Stanislao Morgera
    Department of Nephrology, University Hospital Charite, Berlin, Germany
    Crit Care Med 30:107-12. 2002
    ....
  28. ncbi request reprint Septic acute kidney injury in critically ill patients: clinical characteristics and outcomes
    Sean M Bagshaw
    Department of Intensive Care and Department of Medicine, Austin and Repatriation Medical Centre, Melbourne, Australia
    Clin J Am Soc Nephrol 2:431-9. 2007
    ..Patients with septic AKI had an increased risk for death and longer duration of hospitalization yet showed trends toward greater renal recovery and independence from RRT...
  29. ncbi request reprint Cytokine dialysis: an ex vivo study
    Shigehiko Uchino
    Department of Intensive Care and Medicine, Austin and Repatriation Medical Centre, Melbourne, Victoria, Australia
    ASAIO J 48:650-3. 2002
    ..We conclude that cytokine dialysis is achievable through a membrane with a high cut-off point with negligible albumin loss. These findings support the technical feasibility of this new approach to blood purification in sepsis...
  30. ncbi request reprint The hazards of whirlpooling
    Lutz Liefeldt
    Lancet 361:534. 2003
  31. doi request reprint Treatment of severe hypercalcemia using continuous renal replacement therapy with regional citrate anticoagulation
    Detlef Kindgen-Milles
    University Hospital Dusseldorf, Department of Anaesthesiology, Heinrich Heine University, Dusseldorf, Germany
    ASAIO J 54:442-4. 2008
    ..The time delay between adjustment in calcium infusion rate and the first detectable change in ionized calcium level was below 4 hours. However, the full response to a change of the calcium substitution was found after 8-12 hours...
  32. doi request reprint N-Acetylcysteine does not artifactually lower plasma creatinine concentration
    Michael Haase
    Director of Intensive Care Research, Austin Hospital, University of Melbourne, 3084 Heidelberg, Victoria, Australia
    Nephrol Dial Transplant 23:1581-7. 2008
    ..However, it has been suggested that NAC may lower plasma creatinine levels independent of any effects on glomerular filtration rate (GFR)...
  33. ncbi request reprint Sodium citrate anticoagulation during sustained low efficiency dialysis (SLED) in patients with acute renal failure and severely impaired liver function
    Christian Morath
    Nephrol Dial Transplant 23:421-2. 2008
  34. ncbi request reprint External validation of severity scoring systems for acute renal failure using a multinational database
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    Crit Care Med 33:1961-7. 2005
    ..Therefore, it is not known whether such severity scoring systems may be widely applied...
  35. ncbi request reprint Renal vascular resistance in sepsis
    Christoph Langenberg
    Departments of Intensive Care and Medicine, Austin Hospital and University of Melbourne, Heidelberg, Melbourne, Australia
    Nephron Physiol 104:p1-11. 2006
    ..To assess changes in renal vascular resistance (RVR) in human and experimental sepsis and to identify determinants of RVR...
  36. ncbi request reprint Continuous renal replacement therapy: a worldwide practice survey. The beginning and ending supportive therapy for the kidney (B.E.S.T. kidney) investigators
    Shigehiko Uchino
    Jikei University School of Medicine, Intensive Care Unit, Department of Anesthesiology, Tokyo, Japan
    Intensive Care Med 33:1563-70. 2007
    ..Little information is available regarding current practice in continuous renal replacement therapy (CRRT) for the treatment of acute renal failure (ARF) and the possible clinical effect of practice variation...
  37. ncbi request reprint Hemodialysis membrane with a high-molecular-weight cutoff and cytokine levels in sepsis complicated by acute renal failure: a phase 1 randomized trial
    Michael Haase
    Intensive Care Unit, Austin Hospital, University of Melbourne, Australia
    Am J Kidney Dis 50:296-304. 2007
    ..However, standard hemodialysis membranes achieve only little diffusive removal of circulating cytokines. Modified membranes may enable both successful IHD treatment and simultaneous diffusive cytokine removal...
  38. ncbi request reprint Acute renal failure in critically ill patients: a multinational, multicenter study
    Shigehiko Uchino
    Department of Intensive Care, Austin Hospital, Melbourne, Australia
    JAMA 294:813-8. 2005
    ....
  39. pmc Renal blood flow in sepsis
    Christoph Langenberg
    Department of Intensive Care, Austin Hospital, and University of Melbourne, Heidelberg, Melbourne, Australia
    Crit Care 9:R363-74. 2005
    ..To assess changes in renal blood flow (RBF) in human and experimental sepsis, and to identify determinants of RBF...
  40. ncbi request reprint Diuretics and mortality in acute renal failure
    Shigehiko Uchino
    Department of Intensive Care, Austin and Repatriation Medical Centre, Melbourne, Australia
    Crit Care Med 32:1669-77. 2004
    ..The administration of diuretics in such patients has been discouraged. Our objective was to determine the impact of diuretics on the mortality rate of critically ill patients with acute renal failure...
  41. ncbi request reprint Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients
    Michael Haase
    Department of Intensive Care, Austin Hospital, University of Melbourne, Australia
    Crit Care Med 35:1324-31. 2007
    ..To assess the effect of high-dose N-acetylcysteine on renal function in cardiac surgery patients at higher risk of postoperative renal failure...
  42. ncbi request reprint Successful pregnancies in dialysis patients including those suffering from cystinosis and familial Mediterranean fever
    Michael Haase
    Department of Nephrology, Charite University Medicine, Berlin Germany
    J Nephrol 19:677-81. 2006
    ..These modified management guidelines have led to a favourable outcome in all our patients including two patients with familial Mediterranean fever and with cystinosis, and may help to guide therapy in other pregnant dialysis patients...
  43. pmc Myoglobin clearance by super high-flux hemofiltration in a case of severe rhabdomyolysis: a case report
    Toshio Naka
    Department of Intensive Care, Melbourne University, Austin Hospital, Melbourne, Australia
    Crit Care 9:R90-5. 2005
    ..To test the ability of a novel super high-flux (SHF) membrane with a larger pore size to clear myoglobin from serum...