Matthias C, Jahnke V, Fryer A, Strange R. [Influence of glutathione s-transferase and cytochrome p450 polymorphisms on prognosis of head and neck cancer]. Laryngorhinootologie. 2002;81:406-12 pubmed
..The data demonstrate site-dependent associations between GSTT1 null and CYP2D6 PM and tumor extension and lymph node involvement in SCC of the head and neck. ..
Matthias C, Jahnke V, Fryer A, Strange R. [First results on the influence of polymorphisms at glutathione S-transferase, cytochrome P450, and tumor necrosis factor gene loci on the development of multiple head and neck cancer]. Laryngorhinootologie. 2003;82:25-30 pubmed
..3 %, B3/B3 : 15.8 %). Patients suffering from multiple SCC development showed a cumulation of high risk genotypes at GST and TNF gene loci. Specific genetic variations could not be determined. ..