C Loddenkemper

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Diagnostic standards in the pathology of inflammatory bowel disease
    Christoph Loddenkemper
    Institute of Pathology Research Center ImmunoSciences, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Dig Dis 27:576-83. 2009
  2. pmc In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer
    Christoph Loddenkemper
    Department of Pathology, Charit Universit tsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Transl Med 4:52. 2006
  3. pmc Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival
    Dirk Nagorsen
    Department of Hematology and Oncology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Transl Med 5:62. 2007
  4. pmc Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis
    Heiner Appel
    Charite Berlin, Campus Benjamin Franklin, Department of Gastroenterology, Infectiology and Rheumatology, Hindenburgdamm 30, 12200 Berlin, Germany
    Arthritis Res Ther 8:R143. 2006
  5. pmc Frequency and diagnostic patterns of lymphomas in liver biopsies with respect to the WHO classification
    Christoph Loddenkemper
    Institute of Pathology, Charite University Medicine Berlin, Berlin, Germany
    Virchows Arch 450:493-502. 2007
  6. doi request reprint Foxp3 and microsatellite stability phenotype in colorectal cancer
    Christoph Loddenkemper
    Institut fur Pathologie, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Gut 57:725-6. 2008
  7. ncbi request reprint [The morphologic variants of KSHV/HHV 8-associated lymphoproliferations]
    C Loddenkemper
    Institut fur Pathologie, Konsultations und Referenzzentrum für Lymphknoten und Hämatopathologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Pathologe 28:46-9. 2007
  8. doi request reprint Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients
    H J Epple
    Department of Gastroenterology, Infectious Diseases and Rheumatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Gut 58:220-7. 2009
  9. doi request reprint Retinoic acid-induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammation
    Astrid Menning
    Experimental Rheumatology, Charite University Medicine, Berlin, Germany
    Eur J Immunol 40:2539-48. 2010
  10. ncbi request reprint [Fever of unknown origin in the 21st century. 2. Non-infectious diseases (autoimmune diseases)]
    T Schneider
    Medizinische Klinik 1 Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Dtsch Med Wochenschr 130:2774-8. 2005

Detail Information

Publications125 found, 100 shown here

  1. doi request reprint Diagnostic standards in the pathology of inflammatory bowel disease
    Christoph Loddenkemper
    Institute of Pathology Research Center ImmunoSciences, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Dig Dis 27:576-83. 2009
    ..g. cytomegalovirus colitis or Epstein-Barr virus-induced lymphoproliferative disorders, and a high degree of awareness by clinicians and pathologists is required in order not to miss these life-threatening complications of IBD...
  2. pmc In situ analysis of FOXP3+ regulatory T cells in human colorectal cancer
    Christoph Loddenkemper
    Department of Pathology, Charit Universit tsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Transl Med 4:52. 2006
    ..However, local Treg infiltration was significantly higher in limited disease, in which a systemic TAA-directed T cell responses is less frequently observed...
  3. pmc Tumor-infiltrating macrophages and dendritic cells in human colorectal cancer: relation to local regulatory T cells, systemic T-cell response against tumor-associated antigens and survival
    Dirk Nagorsen
    Department of Hematology and Oncology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Transl Med 5:62. 2007
    ..The aim of the present study was to analyze macrophage and DC infiltration in CRC and to investigate whether there is a correlation to systemic T-cell response, regulatory T cell (Treg) infiltration, and survival...
  4. pmc Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis
    Heiner Appel
    Charite Berlin, Campus Benjamin Franklin, Department of Gastroenterology, Infectiology and Rheumatology, Hindenburgdamm 30, 12200 Berlin, Germany
    Arthritis Res Ther 8:R143. 2006
    ..This first study correlating histopathological changes in the spine of patients with AS with findings in MRI scans suggests that a substantial degree of bone marrow inflammation and edema is necessary to be detected by MRI...
  5. pmc Frequency and diagnostic patterns of lymphomas in liver biopsies with respect to the WHO classification
    Christoph Loddenkemper
    Institute of Pathology, Charite University Medicine Berlin, Berlin, Germany
    Virchows Arch 450:493-502. 2007
    ..This study provides relevant data on the distribution of hepatic lymphomas and demonstrates the applicability of the WHO classification proposing a diagnostic algorithm for liver biopsies...
  6. doi request reprint Foxp3 and microsatellite stability phenotype in colorectal cancer
    Christoph Loddenkemper
    Institut fur Pathologie, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Gut 57:725-6. 2008
  7. ncbi request reprint [The morphologic variants of KSHV/HHV 8-associated lymphoproliferations]
    C Loddenkemper
    Institut fur Pathologie, Konsultations und Referenzzentrum für Lymphknoten und Hämatopathologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Pathologe 28:46-9. 2007
    ..To the best of our knowledge, liver infiltration by a MCD-associated HHV 8 positive plasmablastic lymphoma has not been documented previously. The differential diagnosis is discussed...
  8. doi request reprint Impairment of the intestinal barrier is evident in untreated but absent in suppressively treated HIV-infected patients
    H J Epple
    Department of Gastroenterology, Infectious Diseases and Rheumatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Gut 58:220-7. 2009
    ..The purpose of this study was to investigate the effect of highly active antiretroviral therapy (HAART) on the HIV-induced intestinal barrier defect and to identify underlying mechanisms...
  9. doi request reprint Retinoic acid-induced gut tropism improves the protective capacity of Treg in acute but not in chronic gut inflammation
    Astrid Menning
    Experimental Rheumatology, Charite University Medicine, Berlin, Germany
    Eur J Immunol 40:2539-48. 2010
    ..Together, our data show that the induction of appropriate homing properties prior to transfer increases the protective potential of adoptively transferred Treg in acute, but not in chronic, inflammatory disorders of the gut...
  10. ncbi request reprint [Fever of unknown origin in the 21st century. 2. Non-infectious diseases (autoimmune diseases)]
    T Schneider
    Medizinische Klinik 1 Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin
    Dtsch Med Wochenschr 130:2774-8. 2005
  11. doi request reprint [Tropheryma whipplei infection. Colonization, self-limiting infection and Whipple's disease]
    V Moos
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Deutschland
    Pathologe 32:362-70. 2011
    ..In the case of Immune reconstitution inflammatory syndrome (IRIS) or inflammatory lesions of the CNS in the setting of Whipple's disease, additional treatment with corticosteroids should be considered to avoid severe tissue damage...
  12. ncbi request reprint Dermatopathic lymphadenopathy: a differential diagnosis of enlarged lymph nodes in uremic pruritus
    T H Westhoff
    Charite, Campus Benjamin Franklin, Medizinische Klinik IV, Nephrology, Hindenburgamm 30, 12200 Berlin, Germany
    Clin Nephrol 66:472-5. 2006
    ..In the present work we describe a rare but probably underdiagnosed cause for enlarged lymph nodes in uremic patients...
  13. ncbi request reprint Chemoembolization of the lung improves tumor control in a rat model
    Paul Schneider
    Department of Surgery, Benjamin Franklin Medical Center, Freie Universitat Berlin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Clin Cancer Res 8:2463-8. 2002
    ....
  14. ncbi request reprint Alpha CD 2 mAb treatment safely attenuates adoptive transfer colitis
    Nina N Pawlowski
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Lab Invest 85:1013-23. 2005
    ..Most likely inhibition of IL-2 secretion and T-cell proliferation are responsible for these effects. Still, immune defence towards T. gondii is maintained...
  15. doi request reprint [Primary ductal adenocarcinoma near the orbit]
    M Grunbaum
    Institut fur Pathologie, Konsultations und Referenzzentrum für Lymphknoten und Hämatopathologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland
    Pathologe 31:279-82. 2010
    ..The tumor could be removed without compromising the eye. The patient suffers no side-effects or recurrences 12 months later...
  16. ncbi request reprint Immunohistologic analysis of zygapophyseal joints in patients with ankylosing spondylitis
    Heiner Appel
    Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    Arthritis Rheum 54:2845-51. 2006
    ..Zygapophyseal joints of the spine are often affected in ankylosing spondylitis (AS). In this study, we undertook a systematic immunohistologic evaluation of the immunopathology of the zygapophyseal joints in patients with advanced AS...
  17. ncbi request reprint Aggravation of intestinal inflammation by depletion/deficiency of gammadelta T cells in different types of IBD animal models
    Anja A Kuhl
    Medizinische Klinik I, and Institute of Pathology, Charite, University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin D 12200, Germany
    J Leukoc Biol 81:168-75. 2007
    ..Particularly, during the early phase of intestinal inflammation, gammadelta T cells appear to be important. The mechanism seems to involve the control of IFN-gamma production and epithelial regeneration...
  18. doi request reprint In vivo diagnosis of acute intestinal graft-versus-host disease by confocal endomicroscopy
    C Bojarski
    Medical Department I Gastroenterology, Infectious Diseases, Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    Endoscopy 41:433-8. 2009
    ..Confocal endomicroscopy (CEM) is a noninvasive method that allows in vivo histology to be performed during endoscopy. The aim of this study was to evaluate CEM for the diagnosis of acute intestinal GvHD...
  19. doi request reprint [Fever of unknown origin in gastroenterology]
    T Schneider
    Medizinische Klinik I, Gastroenterologie Infektiologie Rheumatologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin
    Internist (Berl) 50:668-75. 2009
    ..Nevertheless using these different approaches in most cases of fever of unknown origin the underlying cause can be identified which for many patients means not more or less than significant improvement or even survival...
  20. ncbi request reprint Combination of p53 expression and p21 loss has an independent prognostic impact on sporadic colorectal cancer
    Aurelia Noske
    Institute of Pathology, Charite University Hospital Berlin, Campus Mitte, Berlin, Germany
    Oncol Rep 22:3-9. 2009
    ..6, p=0.027). Our data suggest that the assessment of both p53 and p21 expression may provide prognostic information in colorectal cancer patients. This combination might be helpful to identify patients who could benefit from chemotherapy...
  21. ncbi request reprint Nf-kappab and AP-1 activation is associated with late lumen loss after porcine coronary angioplasty and antiproliferative beta-irradiation
    Carolin Deiner
    Institute of Veterinary Physiology, Faculty of Veterinary Medicine, FU Berlin, Berlin, Germany
    Cardiovasc Res 75:195-204. 2007
    ..We hypothesized that the transcription factors nuclear factor-{kappa}B (NF-kappaB) and activator protein-1 (AP-1) are involved in these processes. We addressed the role of these mediators in a porcine model of coronary restenosis...
  22. doi request reprint Gammadelta T lymphocytes: a new type of regulatory T cells suppressing murine 2,4,6-trinitrobenzene sulphonic acid (TNBS)-induced colitis
    Jorg C Hoffmann
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Int J Colorectal Dis 23:909-20. 2008
    ..However, injury of the mucosa by, i.e. dextran sulphate sodium causes severe inflammation in gammadelta T-cell-deficient mice. We therefore asked whether gammadelta T cells have regulatory functions...
  23. pmc Cytokine expression in the colonic mucosa of human immunodeficiency virus-infected individuals before and during 9 months of antiretroviral therapy
    Hubert Schulbin
    Medizinische Klinik I, Charite, Campus Benjamin Franklin, Berlin, Germany
    Antimicrob Agents Chemother 52:3377-84. 2008
    ..Despite reductions in levels of mucosal HIV RNA and the restoration of mucosal CD4(+) T lymphocytes, antiretroviral therapy failed to restore the normal colonic immunologic environment...
  24. ncbi request reprint A helminth immunomodulator reduces allergic and inflammatory responses by induction of IL-10-producing macrophages
    Corinna Schnoeller
    Department of Molecular Parasitology, Humboldt University, Berlin, Germany
    J Immunol 180:4265-72. 2008
    ..Our data demonstrate that treatment with a single helminth protein can exert the antiallergic effects of helminth infections...
  25. doi request reprint Osteopontin as two-sided mediator of intestinal inflammation
    Katja Heilmann
    Medical Clinic, Charite University Medicine Berlin, Germany
    J Cell Mol Med 13:1162-74. 2009
    ....
  26. ncbi request reprint [Fever of unknown origin in the 21st century: infectious diseases]
    T Schneider
    Medizinische Klinik 1 Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin
    Dtsch Med Wochenschr 130:2708-12. 2005
    ..Therefore and because of economic reasons patients with FUO should be investigated in specialized centres with a department for rheumatology and infectious diseases...
  27. doi request reprint Structural and functional changes of the duodenum in human norovirus infection
    H Troeger
    Department of Gastroenterology, Infectious Diseases and Rheumatology, Campus Benjamin Franklin, Charite Universitatsmedizin, Berlin, Germany
    Gut 58:1070-7. 2009
    ..Norovirus infection is the most frequent cause of infectious diarrhoea in the western world. This study aimed to characterise functionally and histomorphologically the diseased duodenum in human biopsies...
  28. doi request reprint [Immune reconstitution inflammatory syndrome (IRIS) of the small bowel in an immunocompromised patient suffering from systemic lupus erythematosus and non-tuberculous mycobacteriosis]
    S Daum
    Medizinische Klinik I, Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, 12200 Berlin, Deutschland
    Z Rheumatol 67:277-8, 280-3. 2008
    ..Due to different treatment strategies, distinguishing IRIS from infectious diseases is essential. The role of Treg in IRIS has to be elucidated...
  29. doi request reprint [Immunopathology of ankylosing spondylitis and other spondyloarthritides]
    H Appel
    Abteilung für Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    Z Rheumatol 67:25-31. 2008
    ..The molecular mechanisms which promote the transition from inflammation to new bone formation in patients with ankylosing spondylitis are not well understood...
  30. doi request reprint [Nodular regenerative hyperplasia as a side effect of azathioprine in a patient with Crohn's disease]
    M Schumann
    Klinik fur Gastroenterologie, Infektiologie und Rheumatologie, Charite Universitatsmedizin Berlin
    Dtsch Med Wochenschr 133:1897-900. 2008
    ..Examination of the liver histology showed areas of enlarged hyperplastic hepatocytes adjacent to areas of atrophic hepatocytes and dilated sinusoids...
  31. ncbi request reprint Dissemination of a Sjögren's syndrome-associated extranodal marginal-zone B cell lymphoma: circulating lymphoma cells and invariant mutation pattern of nodal Ig heavy- and light-chain variable-region gene rearrangements
    A Hansen
    Dept of Medicine and Outpatient Department, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10098 Berlin, Germany
    Arthritis Rheum 54:127-37. 2006
    ..We undertook this study to analyze lymphoma progression and dissemination outside of the MALT-type lesions...
  32. doi request reprint Chemokine receptor CCR6 expression level and aggressiveness of prostate cancer
    Pirus Ghadjar
    Department of Hematology, Medical Oncology and Transfusion Medicine, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    J Cancer Res Clin Oncol 134:1181-9. 2008
    ..This study was performed to investigate a potential relationship between CCR6 and CCL20 expression and features of human prostate cancer (PCA) at time of primary treatment...
  33. pmc A patient with cerebral Whipple disease with gastric involvement but no gastrointestinal symptoms: a consequence of local protective immunity?
    Harald Prüss
    Department of Neurology, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    J Neurol Neurosurg Psychiatry 78:896-8. 2007
    ....
  34. doi request reprint A case of Erdheim-Chester disease initially mistaken for Ormond's disease
    Konstanze Loddenkemper
    Department of Rheumatology and Clinical Immunology, Charite University Medicine, Berlin, Germany
    Nat Clin Pract Rheumatol 4:50-5. 2008
    ..Re-evaluation of the CT scans and histological biopsy samples revealed unusual sclerosis of the long bones and diffuse infiltrates of foamy histiocytes in the bone marrow and the retroperitoneum...
  35. ncbi request reprint Aggravation of different types of experimental colitis by depletion or adhesion blockade of neutrophils
    Anja A Kuhl
    Medizinische Klinik I, Campus Benjamin Franklin, Charite, Berlin, Germany
    Gastroenterology 133:1882-92. 2007
    ..The objective of this study was to evaluate whether blocking the invasion of neutrophils by anti-L-selectin monoclonal antibodies modulates chemically induced colitis and how this modulation is accomplished...
  36. ncbi request reprint Esophageal giant ulcer in primary human immunodeficiency virus infection is associated with an infiltration of activated T cells
    Britta Siegmund
    Medical Department I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Scand J Gastroenterol 42:890-5. 2007
    ..These observations strongly suggest that infiltration of activated T cells plays a crucial role in the pathogenesis of giant ulcers during primary HIV infection...
  37. ncbi request reprint Chemoembolization with carboplatin of the lung. Feasibility and toxicity in a pig model
    Uwe Pohlen
    Department of Surgery, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Anticancer Res 27:1503-8. 2007
    ..Based on our encouraging results in a rodent model (rat), the aim was to prove the safety and effectiveness of this novel method in a large animal model before clinical application of this therapy...
  38. doi request reprint Magnetic resonance imaging of experimental inflammatory bowel disease: quantitative and qualitative analyses with histopathologic correlation in a rat model using the ultrasmall iron oxide SHU 555 C
    Bernd B Frericks
    Department of Radiology and Nuclear Medicine, Universitätsmedizin Berlin Charité Campus Benjamin Franklin, Berlin, Germany
    Invest Radiol 44:23-30. 2009
    ..To quantitatively and qualitatively characterize the MR findings of inflammatory bowel disease in a rat model after i.v. injection of the reticuloendothelial system cell specific ultrasmall iron oxide SHU 555 C...
  39. doi request reprint Histopathology-based combined surgical approach to rectovaginal endometriosis
    Mandy Mangler
    Department of Gynecology, Charite Campus Mitte, Berlin, Germany
    Int J Gynaecol Obstet 103:59-64. 2008
    ..Only infiltrative disease should be treated by intestinal resection. However, infiltration of endometriosis cannot be confirmed by preoperative imaging techniques...
  40. doi request reprint Chronic norovirus infection in renal transplant recipients
    Timm H Westhoff
    Department of Nephrology, Charite Campus Benjamin Franklin, Berlin, Germany
    Nephrol Dial Transplant 24:1051-3. 2009
    ..Norovirus should therefore be considered in the differential diagnosis of both acute and chronic diarrhoea after transplantation. Reduction of immunosuppression may be indicated to allow virus elimination in symptomatic cases...
  41. doi request reprint Bowel perforation in non-small cell lung cancer after bevacizumab therapy
    Elisabeth Schellhaas
    Chirurgische Klinik I, Charite Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    Invest New Drugs 27:184-7. 2009
    ..Bevacizumab is increasingly used in combination with chemotherapy for treatment of unresectable non-small cell lung cancer. The aim of this report is to underline possible risks associated with this otherwise well-tolerated drug...
  42. ncbi request reprint Chemoembolization of lung metastases--pharmacokinetic behaviour of carboplatin in a rat model
    Uwe Pohlen
    Department of Surgery, Charité Campus Benjamin Franklin Medical Center, Hindenburgdamm 30, D 12200 Berlin, Germany
    Anticancer Res 27:809-15. 2007
    ..To improve tumor control in lung metastases using a novel method: unilateral chemoembolization of the lung by instillation of degradable starch microspheres (DSM) and cytotoxic agents via the pulmonal artery...
  43. ncbi request reprint Increased pontin expression in human colorectal cancer tissue
    Johannes C Lauscher
    Department of General, Vascular and Thoracic Surgery, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Hum Pathol 38:978-85. 2007
    ..These data suggest that upregulation and nuclear localization of pontin together with beta-catenin may contribute to progression of colorectal carcinoma...
  44. pmc Shift towards pro-inflammatory intestinal bacteria aggravates acute murine colitis via Toll-like receptors 2 and 4
    Markus M Heimesaat
    Institut für Mikrobiologie und Hygiene, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    PLoS ONE 2:e662. 2007
    ..We have recently reported that Escherichia coli accumulates in murine ileitis and exacerbates small intestinal inflammation via Toll-like receptor (TLR) signaling...
  45. ncbi request reprint Clinical management and immunohistochemical analysis of umbilical endometriosis
    Sylvia Mechsner
    Department of Gynecology, Endometriosis Research Center Charité, Charite, Campus Benjamin Franklin, Berlin, Germany
    Arch Gynecol Obstet 280:235-42. 2009
    ..To established a strategy for diagnostic and therapeutic management of umbilical endometriosis and to determine the biological character...
  46. pmc High-dose methotrexate is beneficial in parenchymal brain masses of uncertain origin suspicious for primary CNS lymphoma
    Philipp Kiewe
    Department of Hematology, Oncology, and Transfusion Medicine, Charite Campus Benjamin Franklin, Hindenburgdamm 30 31, 12200 Berlin, Germany
    Neuro Oncol 9:96-102. 2007
    ..No symptoms of late neurotoxicity have occurred so far. The response and survival data in this small series of patients are encouraging and suggest a benefit for patients with suspected PCNSL after initial treatment with HDMTX...
  47. doi request reprint Combination of host susceptibility and virulence of Mycobacterium tuberculosis determines dual role of nitric oxide in the protection and control of inflammation
    Martin Beisiegel
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    J Infect Dis 199:1222-32. 2009
    ..Thus, a combination of host susceptibility and M. tuberculosis virulence determines the role of iNOS in the protection and control of inflammation...
  48. ncbi request reprint Mucosal FOXP3+ regulatory T cells are numerically deficient in acute and chronic GvHD
    Kathrin Rieger
    Department of Hematology, Oncology and Transfusion Medicine, Charite Campus Benjamin Franklin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Blood 107:1717-23. 2006
    ..The determination of FOXP3+/CD8+ ratio can be a helpful tool to discriminate GvHD from infectious inflammation after allogeneic stem cell transplantation...
  49. doi request reprint Role of hypoxia-inducible transcription factor 1alpha for progression and chemosensitivity of murine hepatocellular carcinoma
    Katjana Daskalow
    Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany
    J Mol Med (Berl) 88:817-27. 2010
    ..However, our data point toward a significant function of HIF-1alpha in determining chemosensitivity of HCC and therefore warrant validation of HIF-1alpha-inhibitors as adjuvant therapeutic agents in clinical studies of human HCC...
  50. pmc Gut mucosal FOXP3+ regulatory CD4+ T cells and Nonregulatory CD4+ T cells are differentially affected by simian immunodeficiency virus infection in rhesus macaques
    Kristina Allers
    Medical Clinic I Gastroenterology, Infectious Diseases and Rheumatology, Charite Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany
    J Virol 84:3259-69. 2010
    ..Although SIV production is limited in mucosal T(reg), T(reg) accumulation may indirectly contribute to viral persistence by suppressing antiviral immune responses...
  51. doi request reprint Immunohistochemical analysis of osteoblasts in zygapophyseal joints of patients with ankylosing spondylitis reveal repair mechanisms similar to osteoarthritis
    Heiner Appel
    Department of Gastroenterology, Infectiology and Rheumatology, Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Rheumatol 37:823-8. 2010
    ..New bone formation of the spine is a typical feature of ankylosing spondylitis (AS). It is unknown whether new bone formation is part of a physiological repair process or a unique pathological entity of the disease...
  52. doi request reprint Microscopic findings in sigmoid diverticulitis--changes after conservative therapy
    Christoph Holmer
    Department of General, Vascular and Thoracic Surgery, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    J Gastrointest Surg 14:812-7. 2010
    ..The aim of this study was to record time-course changes of inflammation in phlegmonous and abscess-forming diverticulitis after conservative treatment in order to check the indication for surgery...
  53. doi request reprint Possible roles of oxytocin receptor and vasopressin-1α receptor in the pathomechanism of dysperistalsis and dysmenorrhea in patients with adenomyosis uteri
    Sylvia Mechsner
    Endometriosis Research Center, Department of Obstetrics and Gynecology, Charite, Campus Benjamin Franklin, Berlin, Germany
    Fertil Steril 94:2541-6. 2010
    ..To investigate the expression of oxytocin (OTR) and/or vasopressin (VP1αR) receptor in patients with and without adenomyosis uteri...
  54. doi request reprint Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defect
    Hans Jörg Epple
    Medical Clinic I, Gastroenterology, Rheumatology, Infectiology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany
    Gastroenterology 139:1289-300. 2010
    ..We analyzed T-cell subsets, epithelial apoptosis, and barrier function of the duodenal mucosa in patients with acute HIV infection...
  55. doi request reprint MyD88/TLR9 mediated immunopathology and gut microbiota dynamics in a novel murine model of intestinal graft-versus-host disease
    Markus M Heimesaat
    Institut für Mikrobiologie und Hygiene, Charite Universitatsmedizin, Campus Benjamin Franklin, Berlin, Germany
    Gut 59:1079-87. 2010
    ..The bacterial microflora aggravates graft-versus-host-disease (GvHD) after allogeneic stem cell transplantation, but the underlying mechanisms of manifestations of intestinal GvHD (iGvHD) in the gut remain poorly understood...
  56. doi request reprint Viscoelasticity-based staging of hepatic fibrosis with multifrequency MR elastography
    Patrick Asbach
    Department of Radiology, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, Germany
    Radiology 257:80-6. 2010
    ..To analyze the dynamics of the shear modulus of the liver to assess the optimal driving frequency and to determine the diagnostic accuracy of generalized frequency-independent elasticity cutoff values for staging hepatic fibrosis...
  57. pmc Specific and nonspecific B-cell function in the small intestines of patients with Whipple's disease
    Anika Geelhaar
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, CBF, Berlin, Germany
    Infect Immun 78:4589-92. 2010
    ..However, this deficiency does not completely abolish T. whipplei-specific secretory IgA production that nonetheless does not protect from chronic infection...
  58. doi request reprint The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
    Anna Barbara Stittrich
    Deutsches Rheuma ForschungsZentrum Berlin, Berlin, Germany
    Nat Immunol 11:1057-62. 2010
    ..Our results demonstrate a central role for miR-182 in the physiological regulation of IL-2-driven helper T cell-mediated immune responses and open new therapeutic possibilities...
  59. ncbi request reprint Prevention of colitis-associated carcinogenesis in a mouse model by diet supplementation with ursodeoxycholic acid
    Christoph Loddenkemper
    Institut fur Pathologie, Charite Campus Benjamin Franklin, Berlin, Germany
    Int J Cancer 118:2750-7. 2006
    ..These data indicate that UDCA suppresses colitis-associated carcinogenesis. This model is suitable for investigation of the mechanism of the anticarcinogenic effect of UDCA in vivo...
  60. doi request reprint Qualitative and quantitative evaluation of hepatocellular carcinoma and cirrhotic liver enhancement using Gd-EOB-DTPA
    Bernd B Frericks
    Department of Radiology and Nuclear Medicine, Charite Campus Benjamin Franklin, Universitatsmedizin Berlin, Hindenburgdamm 30, 12200 Berlin, Germany
    AJR Am J Roentgenol 193:1053-60. 2009
    ....
  61. doi request reprint Impaired immune functions of monocytes and macrophages in Whipple's disease
    Verena Moos
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, CBF, Berlin, Germany
    Gastroenterology 138:210-20. 2010
    ..However, macrophage activation in Whipple's disease has not been studied systematically so far...
  62. ncbi request reprint CCR7 deficiency causes ectopic lymphoid neogenesis and disturbed mucosal tissue integrity
    Uta E Höpken
    Department of Tumor Genetics and Immunogenetics, Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Blood 109:886-95. 2007
    ..Thus, CCR7 regulates the cellular organization of visceral tissue by governing life-long recirculation of naive and memory lymphocytes under homeostatic conditions...
  63. ncbi request reprint Implant-related inflammatory arthritis
    Thomas Dorner
    Coagulation Unit, Institute of Transfusion Medicine, Charite University Medicine, Berlin, Germany
    Nat Clin Pract Rheumatol 2:53-6; quiz 57. 2006
    ..The patient had received a wrought titanium 6-aluminium 4-vanadium alloy C cage implant 1.5 years previously, following a severe disc prolapse. No signs of rheumatic disease were evident before the C cage was implanted...
  64. ncbi request reprint Endothelin-1 receptor antagonist (LU-135252) improves the microcirculation and course of TNBS colitis in rats
    Martin Kruschewski
    Department of Surgery, Charite University Medical Center Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    Dig Dis Sci 51:1461-70. 2006
    ..Direct improvement of capillary blood flow in the early phase of colitis leads to reduced colitis activity, which underscores the pathogenetic role of the microcirculation in the progression of colitis...
  65. ncbi request reprint Mucosal but not peripheral FOXP3+ regulatory T cells are highly increased in untreated HIV infection and normalize after suppressive HAART
    Hans Jörg Epple
    Medical Clinic I, Gastroenterology, Rheumatology, Infectiology Charité Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Blood 108:3072-8. 2006
    ..Their role may be 2-edged: attenuating HIV-induced immune hyperactivation while suppressing the immune response to HIV and mucosal pathogens...
  66. ncbi request reprint A novel sporadic Burkitt lymphoma cell line (BLUE-1) with a unique t(6;20)(q15;q11.2) rearrangement
    Thomas Burmeister
    Medizinische Klinik III, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Leuk Res 30:1417-23. 2006
    ..Our findings are discussed in light of the current understanding of endemic and sporadic Burkitt lymphoma. BLUE-1 grows well in culture and should be a useful lymphoma research tool...
  67. ncbi request reprint Robo1/Robo4: differential expression of angiogenic markers in colorectal cancer
    Jörn Gröne
    Department of Surgery, Charite Medical School Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Oncol Rep 15:1437-43. 2006
    ..Therefore, the Robo proteins provide potential target structures for the anti-tumorigenic and anti-angiogenic therapy of colorectal carcinoma...
  68. ncbi request reprint Selective COX-2 inhibition reduces leukocyte sticking and improves the microcirculation in TNBS colitis
    Martin Kruschewski
    Department of Surgery, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Dig Dis Sci 51:662-70. 2006
    ..The results support the described correlation between cyclooxygenase activation and leukocyte-endothelium interaction. Moreover, they underscore the postulated relation between leukocyte-endothelium interaction and capillary blood flow...
  69. ncbi request reprint Hydrops lysosomalis generalisatus--an underestimated side effect of hydroxyethyl starch therapy?
    Martin Schmidt-Hieber
    Medizinische Klinik III Hämatologie, Onkologie und Transfusionsmedizin, Charite Campus Benjamin Franklin, Berlin, Germany
    Eur J Haematol 77:83-5. 2006
    ..We found severe infiltration of foamy cell degenerated macrophages in both organ systems, indicating that sequelae of HES therapy have to be included in the differential diagnosis of bone marrow and liver dysfunction...
  70. ncbi request reprint A souvenir from the Canary Islands
    Rajan Somasundaram
    Department of Gastroenterology, Charite, Campus Benjamin Franklin, Hindenburgdamn 30, 12200 Berlin, Germany
    Lancet 367:1116. 2006
  71. ncbi request reprint Regulatory (FOXP3+) T cells as target for immune therapy of cervical intraepithelial neoplasia and cervical cancer
    Christoph Loddenkemper
    Department of Pathology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Cancer Sci 100:1112-7. 2009
    ..We therefore regard CIN and cervical cancer as prime targets for new immune-based non-invasive therapies...
  72. ncbi request reprint Extrapulmonary small cell carcinoma (EPSCC): 10 years' multi-disciplinary experience at Charité
    Sebastian Ochsenreither
    Charite, Campus Benjamin Franklin, Department of Medicine III Hematology and Oncology, Hindenburgdamm 30, 12200 Berlin, Germany
    Anticancer Res 29:3411-5. 2009
    ..Extrapulmonary small cell carcinoma (EPSCC) is a rare disease of highly proliferating neuroendocrine tumor cells. Therapy and outcome of EPSCC patients treated at our institution were retrospectively analyzed...
  73. doi request reprint Persistence of effector memory Th1 cells is regulated by Hopx
    Inka Albrecht
    German Rheumatism Research Center Berlin, Berlin, Germany
    Eur J Immunol 40:2993-3006. 2010
    ..Consequently, they cannot induce chronic inflammation in murine models of transfer-induced colitis and arthritis, demonstrating a key role of Hopx for Th1-mediated immunopathology...
  74. ncbi request reprint [Neurotuberculosis: a continuing clinical challenge]
    B M Mackert
    Klinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Nervenarzt 79:153-66. 2008
    ..Resistant new strains of the pathogen, Mycobacterium tuberculosis, complicate therapy. Recent discoveries especially in diagnosis and therapy are explained using case evidence...
  75. doi request reprint UDCA slows down intestinal cell proliferation by inducing high and sustained ERK phosphorylation
    S Krishna-Subramanian
    Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Int J Cancer 130:2771-82. 2012
    ..These data extend our understanding of the physiological and potentially chemopreventive effects of UDCA and identify new targets for chemoprevention...
  76. doi request reprint Lipocalin2 protects against airway inflammation and hyperresponsiveness in a murine model of allergic airway disease
    A M Dittrich
    Department of Pediatric Pneumology and Immunology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Clin Exp Allergy 40:1689-700. 2010
    ..Allergen-induced bronchial asthma is a chronic airway disease that involves the interplay of various genes with environmental factors triggering different inflammatory pathways...
  77. ncbi request reprint [Oral EBV-associated diffuse large B-cell lymphomas in HIV-negative immunocompromised patients]
    K Rhinow
    Abteilung für Oralchirurgie und zahnärztliche Röntgenologie, Zentrum für Zahnmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin
    Mund Kiefer Gesichtschir 10:155-61. 2006
    ..Clinically, a soft, nonpainful, swelling measuring 1.5x0.5x0.5 cm with a central ulceration was evident. The tumor was excised followed by local radiation therapy. No recurrence was noted during a 15-year-follow-up...
  78. ncbi request reprint Rheumatoid arthritis and ankylosing spondylitis - pathology of acute inflammation
    H Appel
    Department of Gastroenterology, Infectiology and Rheumatology, Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    Clin Exp Rheumatol 27:S15-9. 2009
    ..Structural damage defines the outcome in both diseases. However, in AS it is defined by new bone formation and in RA by the destruction of cortical bone...
  79. doi request reprint In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance
    Christian Buschow
    Institute of Immunology, Charite Campus Benjamin Franklin, Berlin, Germany
    J Immunol 184:2930-8. 2010
    ....
  80. pmc Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction
    Cornelia Doebis
    Départemente of Experimentelle Rheumatologie, Charite, Campus Mitte, Berlin, Germany
    Am J Pathol 173:1067-76. 2008
    ..However, only the presence of selectin ligands on T cells was critical for the inflammatory reaction. These findings reveal T cells as the predominant targets for selectin blockade that aim to suppress skin inflammation...
  81. ncbi request reprint Immune reconstitution inflammatory syndrome of the small bowel in a human immunodeficiency virus-negative patient
    Severin Daum
    Department of Medicine I, Gastroenterology, Infectious Diseases and Rheumatology, Charite Medical School Berlin, Campus Benjamin Franklin, Berlin, Germany
    Clin Gastroenterol Hepatol 5:e27-8. 2007
  82. doi request reprint Priming of CD4+ T cells by liver sinusoidal endothelial cells induces CD25low forkhead box protein 3- regulatory T cells suppressing autoimmune hepatitis
    Nils Kruse
    Medical Clinic I, Charite Campus Benjamin Franklin, Berlin, Germany
    Hepatology 50:1904-13. 2009
    ..Furthermore, these cells suppressed hepatic inflammation as monitored by alanine aminotransferase levels and cellular infiltrates in a T cell-mediated autoimmune hepatitis model in vivo...
  83. doi request reprint Mesenteric fat - control site for bacterial translocation in colitis?
    A Batra
    Medical Department I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Mucosal Immunol 5:580-91. 2012
    ..These effects can be considered as protective mechanisms of the mesenteric fat in the defense of bacterial translocation...
  84. pmc Wotherspoon criteria combined with B cell clonality analysis by advanced polymerase chain reaction technology discriminates covert gastric marginal zone lymphoma from chronic gastritis
    M Hummel
    Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, D 12200 Berlin, Germany
    Gut 55:782-7. 2006
    ..However, there is controversy as to whether B cell clonality also exists in chronic gastritis, hence rendering this approach futile at present...
  85. ncbi request reprint Mesangial IgA deposition in minimal change nephrotic syndrome: coincidence of different entities or variant of minimal change disease?
    T H Westhoff
    Charite Campus Benjamin Franklin, Medical Clinic IV, Nephrology, Hindenburgdamm 30, Berlin, Germany
    Clin Nephrol 65:203-7. 2006
    ..We describe 2 cases of MCA with analogue histological findings but relevant differences in clinical presentation, and we discuss the clinical implications of mesangial IgA deposition in minimal change nephrotic syndrome...
  86. doi request reprint The immune response to sporadic colorectal cancer in a novel mouse model
    M Czéh
    Institute of Immunology, Charite Campus Benjamin Franklin, Berlin, Germany
    Oncogene 29:6591-602. 2010
    ..We report, for the first time, a mouse model based on stochastic, tissue-specific activation of a dormant oncogene in the colon allowing the analysis of antitumor immune response against primary colorectal cancer...
  87. pmc Comparative analysis of mononuclear cells isolated from mucosal lymphoid follicles of the human ileum and colon
    Y Junker
    Department of Gastroenterology Infectious Diseases, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Clin Exp Immunol 156:232-7. 2009
    ..The cellular composition of LFMC from ileum and colon is similar, and both secrete predominantly T helper type 1 cytokines...
  88. pmc Correlation of T cell response and bacterial clearance in human volunteers challenged with Helicobacter pylori revealed by randomised controlled vaccination with Ty21a-based Salmonella vaccines
    T Aebischer
    Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
    Gut 57:1065-72. 2008
    ..Helicobacter pylori remains a global health hazard, and vaccination would be ideal for its control. Natural infection appears not to induce protective immunity. Thus, the feasibility of a vaccine for humans is doubtful...
  89. ncbi request reprint [Intestinal tuberculosis: a clinical and diagnostic challenge]
    T Schneider
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik Gastroenterologie, Infektiologie und Rheumatologie
    Dtsch Med Wochenschr 129:1747-52. 2004
  90. ncbi request reprint [Hyperkeratotic inverted seborrheic keratosis of the outer auditory canal : a first description]
    P Halleck
    Klinik mit Polikliniken für Hals Nasen Ohrenheilkunde, Universitätsmedizin Charité Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland
    HNO 57:480-3. 2009
    ..An uncritical diagnosis must be avoided, since these lesions and especially the irritated subtype might be falsely assessed as basal cell carcinomas which they may resemble histologically...
  91. pmc Cellular senescence predicts treatment outcome in metastasised colorectal cancer
    A M Haugstetter
    Medical Department of Hematology, Oncology and Tumor Immunology, Molekulares Krebsforschungszentrum der Charité MKFZ, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Br J Cancer 103:505-9. 2010
    ..Cellular senescence is a terminal cell-cycle arrest that occurs in response to activated oncogenes and DNA-damaging chemotherapy. Whether cancer cell senescence at diagnosis might be predictive for treatment outcome is unknown...
  92. doi request reprint Long-term reduction in local inflammation by a lipid raft molecule in atopic dermatitis
    S Dölle
    Charite Universitatsmedizin Berlin, Department of Dermatology and Allergology, Berlin, Germany
    Allergy 65:1158-65. 2010
    ..With this controlled clinical study, the clinical and immunomodulatory efficacy of miltefosine was investigated in patients with AD in comparison with a topical corticosteroid treatment...
  93. ncbi request reprint Presence of mature DC-Lamp+ dendritic cells in sentinel and non-sentinel lymph nodes of breast cancer patients
    A Bembenek
    Department of Surgery and Surgical Oncology, Robert Rössle Clinic at Helios Klinikum Berlin, Charite University Medicine Berlin, Campus Buch, Lindenberger Weg 80, D13125 Berlin, Germany
    Eur J Surg Oncol 34:514-8. 2008
    ..Our study examined differences in the presence of mature, DC-Lamp+ DC in the SLN and non-SLN according to the extent of metastatic involvement...
  94. doi request reprint Gastrointestinal nematode infection interferes with experimental allergic airway inflammation but not atopic dermatitis
    S Hartmann
    Department of Molecular Parasitology, Humboldt University Berlin, Berlin, Germany
    Clin Exp Allergy 39:1585-96. 2009
    ....
  95. ncbi request reprint Long-term clopidogrel administration following severe coronary injury reduces proliferation and inflammation via inhibition of nuclear factor-kappaB and activator protein 1 activation in pigs
    K Pels
    Charite Campus Benjamin Franklin, Berlin, Germany
    Eur J Clin Invest 39:174-82. 2009
    ..To understand the molecular mechanism, we also investigated the effects on transcription factors nuclear factor-kappaB (NF-kappaB) and activator protein 1 (AP-1)...
  96. ncbi request reprint Anti-CD30 human IL-2 fusion proteins display strong and specific cytotoxicity in vivo
    B Hirsch
    Institute for Pathology, Charite Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany
    Curr Drug Targets 10:110-7. 2009
    ..The data indicate that there are several promising approaches in CD30-targeted immunotherapy. The findings of the anti-CD30 IL-2 constructs suggest that these fusion proteins are particularly useful to remove small, residual tumors...
  97. ncbi request reprint Oncogene-induced senescence as an initial barrier in lymphoma development
    Melanie Braig
    Charité Universitätsmedizin Berlin Haematology Oncology, 13353 Berlin, Germany
    Nature 436:660-5. 2005
    ..These results identify H3K9me-mediated senescence as a novel Suv39h1-dependent tumour suppressor mechanism whose inactivation permits the formation of aggressive but apoptosis-competent lymphomas in response to oncogenic Ras...
  98. ncbi request reprint Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
    Jochen Maul
    Medical Clinic I, Charite University Medicine Berlin, Germany
    Gastroenterology 128:1868-78. 2005
    ..The aim of this study was to determine whether disease activity in IBD correlates with changes in frequency of T(reg) cells and their distribution in the intestinal mucosa...
  99. ncbi request reprint Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis
    Katja Derkow
    Department of Hepatology and Gastroenterology, Charite Universitatsmedizin Berlin, CVK, Berlin, Germany
    Hepatology 46:1155-65. 2007
    ..The models presented here are valuable to investigate the priming of T-cells in the liver and their role in the development of autoimmune disease of the liver...
  100. pmc Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease
    Katharina Lahl
    Institut fur Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universitat Munchen, 81675 Munich, Germany
    J Exp Med 204:57-63. 2007
    ..Furthermore, DEREG mice will allow a more precise definition of the function of Foxp3+ T reg cells in immune reactions in vivo...
  101. ncbi request reprint Diagnostic value of endoscopy for the diagnosis of giardiasis and other intestinal diseases in patients with persistent diarrhea from tropical or subtropical areas
    Ulrich Wahnschaffe
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medical Clinic I Gastroenterology, Infectious Diseases, and Rheumatology, Berlin, Germany
    Scand J Gastroenterol 42:391-6. 2007
    ..The role of endoscopy in the identification of other causes of chronic diarrhea acquired during travel abroad was also evaluated...