Solveigh Krusekopf

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43
    Solveigh Krusekopf
    Institute of Clinical Pharmacology, Charite, Humboldt University of Berlin, Schumannstr 20 21, D 10098, Berlin, Germany
    Eur J Pharmacol 466:7-12. 2003
  2. ncbi request reprint St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways
    Solveigh Krusekopf
    Institute of Clinical Pharmacology, Charite Campus Mitte, Charite University Medical Center, Humboldt University of Berlin, Berlin, Germany
    Pharmacogenet Genomics 15:817-29. 2005

Collaborators

Detail Information

Publications2

  1. ncbi request reprint Differential drug-induced mRNA expression of human CYP3A4 compared to CYP3A5, CYP3A7 and CYP3A43
    Solveigh Krusekopf
    Institute of Clinical Pharmacology, Charite, Humboldt University of Berlin, Schumannstr 20 21, D 10098, Berlin, Germany
    Eur J Pharmacol 466:7-12. 2003
    ..St. John's wort also increased CYP3A4 mRNA exclusively, leaving CYP3A5 and CYP3A43 unaffected, whereas CYP3A7 was decreased. Depending on the inducer, expression of CYP3A4 is differently regulated from CYP3A5, CYP3A7, and CYP3A43...
  2. ncbi request reprint St. John's wort and its constituent hyperforin concordantly regulate expression of genes encoding enzymes involved in basic cellular pathways
    Solveigh Krusekopf
    Institute of Clinical Pharmacology, Charite Campus Mitte, Charite University Medical Center, Humboldt University of Berlin, Berlin, Germany
    Pharmacogenet Genomics 15:817-29. 2005
    ..The effects of St. John's wort and hyperforin on gene expression were analysed in HepG2 cells by Affymetrix microarray hybridization and real time reverse transcription-PCR...