D Keh

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite University Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Crit Care 14:R119. 2010
  2. ncbi Response of neonatal platelets to nitric oxide in vitro
    D Keh
    Clinic of Anesthesiology and Intensive Care Medicine, Humboldt University of Berlin, Germany
    Intensive Care Med 27:283-6. 2001
  3. ncbi Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study
    Didier Keh
    Department of Anesthesiology and Intensive Care Medicine, Humbolt University, Berlin, Germany
    Am J Respir Crit Care Med 167:512-20. 2003
  4. ncbi Inactivation of platelet glycoprotein IIb/IIIa receptor by nitric oxide donor 3-morpholino-sydnonimine
    Didier Keh
    Department of Anaesthesiology, Charite Campus Virchow Klinikum, Berlin, Germany
    Blood Coagul Fibrinolysis 14:327-34. 2003
  5. ncbi Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course
    S Spielmann
    Department of Anaesthesiology and Intensive Care Medicine, Charite Virchow Hospital, Humboldt University, Berlin, Germany
    Acta Anaesthesiol Scand 45:364-70. 2001
  6. ncbi Impact of bolus application of low-dose hydrocortisone on glycemic control in septic shock patients
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum and Campus Mitte, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Intensive Care Med 33:730-3. 2007
  7. ncbi Bolus or continuous hydrocortisone--that is the question
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite, Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    Crit Care 11:113. 2007
  8. ncbi Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial
    Christian Meisel
    Department of Medical Immunology, Charite Campus Mitte, Berlin, Germany
    Am J Respir Crit Care Med 180:640-8. 2009
  9. ncbi Use of corticosteroid therapy in patients with sepsis and septic shock: an evidence-based review
    Didier Keh
    , , Berlin, Germany
    Crit Care Med 32:S527-33. 2004
  10. ncbi Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine
    Paul E Marik
    Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Crit Care Med 36:1937-49. 2008

Detail Information

Publications17

  1. ncbi Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite University Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Crit Care 14:R119. 2010
    ..Non-excitable muscle membrane indicates critical illness myopathy (CIM) during early critical illness. We investigated predisposing risk factors for non-excitable muscle membrane at onset of critical illness...
  2. ncbi Response of neonatal platelets to nitric oxide in vitro
    D Keh
    Clinic of Anesthesiology and Intensive Care Medicine, Humboldt University of Berlin, Germany
    Intensive Care Med 27:283-6. 2001
    ..We investigated the response of platelets from neonates, their mothers, and nonpregnant controls to the NO donor SIN-1 in vitro...
  3. ncbi Immunologic and hemodynamic effects of "low-dose" hydrocortisone in septic shock: a double-blind, randomized, placebo-controlled, crossover study
    Didier Keh
    Department of Anesthesiology and Intensive Care Medicine, Humbolt University, Berlin, Germany
    Am J Respir Crit Care Med 167:512-20. 2003
    ..In conclusion, hydrocortisone therapy restored hemodynamic stability and differentially modulated the immunologic response to stress in a way of antiinflammation rather than immunosuppression...
  4. ncbi Inactivation of platelet glycoprotein IIb/IIIa receptor by nitric oxide donor 3-morpholino-sydnonimine
    Didier Keh
    Department of Anaesthesiology, Charite Campus Virchow Klinikum, Berlin, Germany
    Blood Coagul Fibrinolysis 14:327-34. 2003
    ..Whereas spontaneous receptor inactivation may be enhanced by exogenous NO, platelet-derived NO is not involved in receptor inactivation...
  5. ncbi Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course
    S Spielmann
    Department of Anaesthesiology and Intensive Care Medicine, Charite Virchow Hospital, Humboldt University, Berlin, Germany
    Acta Anaesthesiol Scand 45:364-70. 2001
    ..Furthermore, both soluble TNF receptor proteins (sTNF-R1 and sTNF-R2) were described to influence the post-traumatic inflammatory response and organ dysfunction...
  6. ncbi Impact of bolus application of low-dose hydrocortisone on glycemic control in septic shock patients
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum and Campus Mitte, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Intensive Care Med 33:730-3. 2007
    ..To determine whether glycemic control is less feasible when hydrocortisone is given as a bolus compared with continuous application in septic shock patients...
  7. ncbi Bolus or continuous hydrocortisone--that is the question
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite, Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    Crit Care 11:113. 2007
    ..They found continuous infusion of hydrocortisone to be associated with fewer hyperglycaemic episodes and reduced staff workload compared with bolus application...
  8. ncbi Granulocyte-macrophage colony-stimulating factor to reverse sepsis-associated immunosuppression: a double-blind, randomized, placebo-controlled multicenter trial
    Christian Meisel
    Department of Medical Immunology, Charite Campus Mitte, Berlin, Germany
    Am J Respir Crit Care Med 180:640-8. 2009
    ..Sustained sepsis-associated immunosuppression is associated with uncontrolled infection, multiple organ dysfunction, and death...
  9. ncbi Use of corticosteroid therapy in patients with sepsis and septic shock: an evidence-based review
    Didier Keh
    , , Berlin, Germany
    Crit Care Med 32:S527-33. 2004
    ....
  10. ncbi Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine
    Paul E Marik
    Division of Pulmonary and Critical Care Medicine, Thomas Jefferson University, Philadelphia, PA, USA
    Crit Care Med 36:1937-49. 2008
    ..To develop consensus statements for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients...
  11. ncbi Hydrocortisone therapy for patients with septic shock
    Charles L Sprung
    Hadassah Hebrew University Medical Center, Jerusalem, Israel 91120
    N Engl J Med 358:111-24. 2008
    ....
  12. ncbi Adrenal function in sepsis: the retrospective Corticus cohort study
    Diane Lipiner Friedman
    Service de Reanimation, Hôpital Raymond Poincaré APHP, Faculté de Médecine Paris Ile de France Ouest UVSQ, Garches, France
    Crit Care Med 35:1012-8. 2007
    ..To refine the value of baseline and adrenocorticotropin hormone (ACTH)-stimulated cortisol levels in relation to mortality from severe sepsis or septic shock...
  13. ncbi Clinical equipoise remains for issues of adrenocorticotropic hormone administration, cortisol testing, and therapeutic use of hydrocortisone
    Djillali Annane
    Crit Care Med 31:2250-1; author reply 2252-3. 2003
  14. ncbi Dose-response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized, controlled study
    Herwig Gerlach
    Vivantes Klinikum Neukoelln, Klinik für Anaesthesie, operative Intensivmedizin und Schmerztherapie, Rudower Strasse 48, D 12313 Berlin, Germany
    Am J Respir Crit Care Med 167:1008-15. 2003
    ..Hence, previous trials on therapy with inhaled NO in ARDS should be carefully interpreted, as they used constant NO concentrations, which may have become overdoses leading to deterioration of oxygenation after several days...
  15. ncbi Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
    R Phillip Dellinger
    Crit Care Med 32:858-73. 2004
    ..The impact of these guidelines will be formally tested and guidelines updated annually and even more rapidly as some important new knowledge becomes as available...
  16. ncbi Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
    R Phillip Dellinger
    Section of Critical Care Medicine, Cooper University Hospital, One Cooper Plaza, 393 Dorrance, Camden, NJ 08103, USA
    Intensive Care Med 30:536-55. 2004
    ..The impact of these guidelines will be formally tested and guidelines updated annually, and even more rapidly when some important new knowledge becomes available...
  17. ncbi Corticosteroids for severe sepsis and septic shock: a systematic review and meta-analysis
    Djillali Annane
    Critical Care Department, Universite de Versailles Saint Quentin en Yvelines, Assistance Publique Hopitaux de Paris, Hopital Raymond Poincare, Garches 92380, France
    BMJ 329:480. 2004
    ..To assess the effects of corticosteroids on mortality in patients with severe sepsis and septic shock...