Research Topics
| C IkonomidouSummaryAffiliation: Humboldt University Country: Germany Publications
| Collaborators
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Detail Information
Publications
Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brainC Ikonomidou
Department of Pediatric Neurology, Charite Virchow Clinics, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
Science 283:70-4. 1999..These findings may have relevance to human neurodevelopmental disorders involving prenatal (drug-abusing mothers) or postnatal (pediatric anesthesia) exposure to drugs that block NMDA receptors...
Neuronal death enhanced by N-methyl-D-aspartate antagonistsC Ikonomidou
Department of Pediatric Neurology, Children s Hospital, Charite Virchow Clinics, Humboldt University, Augustenburger Platz 1, D 13353 Berlin, Germany
Proc Natl Acad Sci U S A 97:12885-90. 2000....
Neurotransmitters and apoptosis in the developing brainC Ikonomidou
Department of Pediatric Neurology, Charite, Virchow Clinics, Humboldt University, Augustenburger Platz 1, 13353 Berlin, Germany
Biochem Pharmacol 62:401-5. 2001..In addition, there is basis for concern that agents used in pediatric and obstetrical medicine for purposes of sedation, anesthesia, and seizure management may cause apoptotic neuronal death in the developing human brain...
Glutamate antagonists limit tumor growthW Rzeski
Department of Pediatric Neurology, Children's Hospital, Charite-Virchow Campus, Humboldt University, Augustenburger Platz 1, D-13353 Berlin, Germany
Proc Natl Acad Sci U S A 98:6372-7. 2001..Furthermore, glutamate antagonists decreased motility and invasive growth of tumor cells. These findings suggest anticancer potential of glutamate antagonists...
Acute and long-term proteome changes induced by oxidative stress in the developing brainA M Kaindl
Department of Pediatric Neurology, Charite, University Medical School, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
Cell Death Differ 13:1097-109. 2006..These effects are age-dependent, as they did not occur in mice subjected to hyperoxia in adolescence...
Antiepileptic drugs and the developing brainA M Kaindl
Department of Pediatric Neurology, Charit, University Medicine Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Cell Mol Life Sci 63:399-413. 2006....
Accumulation of the anandamide precursor and other N-acylethanolamine phospholipids in infant rat models of in vivo necrotic and apoptotic neuronal deathH H Hansen
Department of Pharmacology, The Royal Danish School of Pharmacy, Copenhagen, Denmark
J Neurochem 76:39-46. 2001..Consequently, our data suggest that excitotoxic necrotic mechanisms of neurodegeneration, as opposed to apoptotic neurodegeneration, have a profound effect on in vivo NAE precursor homeostasis...
Apoptosis in the in vivo mammalian forebrainK Dikranian
Department of Psychiatry Washington University School of Medicine, 4940 Children's Place, St. Louis, Missouri 63110, USA
Neurobiol Dis 8:359-79. 2001....
