Affiliation: Humboldt University
- Update on intracranial hypertension and hypotensionJan Hoffmann
aDepartment of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany bDepartment of Neurology, Headache Group, University of California San Francisco, San Francisco, California
Curr Opin Neurol 26:240-7. 2013..The aim of this article is to review recent findings on the pathophysiology of idiopathic changes in intracranial pressure. The review will focus on idiopathic intracranial hypertension (IIH) and spontaneous intracranial hypotension (SIH)...
- Scientific advances in headache research: an update on neurostimulationJan Hoffmann
Department of Neurology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
Expert Rev Neurother 13:15-7. 2013..The latest scientific and clinical advances were presented at the recent European Headache and Migraine Trust International Congress (EHMTIC) in London (UK)...
- Intracisternal injection of inflammatory soup activates the trigeminal nerve systemJ Hoffmann
Charite Universitatsmedizin Berlin, Department of Neurology, 10117 Berlin, Germany
Cephalalgia 29:1212-7. 2009..The inhibition of CGRP release by topiramate offers a possible mechanism that may in part account for the preventative antimigraine activity of this drug...
- CGRP release and c-fos expression within trigeminal nucleus caudalis of the rat following glyceryltrinitrate infusionN Offenhauser
Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
Cephalalgia 25:225-36. 2005..Both GTN and L-NAME reduced capsaicin-induced c-fos LI. This is most likely due to a feedback inhibition of nitric oxide synthases, which indicates that the c-fos response to capsaicin within TNC is mediated by NO dependent mechanisms...
- [Treatment of migraine]J Hoffmann
Neurologische Klinik und Poliklinik, Charite Universitatsmedizin Berlin, Berlin, Germany
Dtsch Med Wochenschr 132:2153-8. 2007..Prophylactic drugs of first choice are Betablockers (Propranolol and Metoprolol), Topiramate and Flunarizine. Prophylactic treatment should be administered over a period of at least 6 - 12 months...