Bert Hildebrandt

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. pmc Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature
    Alexander Stein
    University Cancer Center Hamburg, Germany
    BMC Cancer 12:356. 2012
  2. ncbi request reprint [Standards and perspectives in locoregional hyperthermia]
    Bert Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Berlin, Deutschland
    Wien Med Wochenschr 154:148-58. 2004
  3. ncbi request reprint Differential gene expression in peripheral blood lymphocytes of cancer patients treated with whole body hyperthermia and chemotherapy: a pilot study
    Bert Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin der Humboldt Universität, Berlin, Germany
    Int J Hyperthermia 22:625-35. 2006
  4. pmc Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: a Phase II-study and historical comparison with the surgical approach
    Bert Hildebrandt
    CharitéCentrum fur Tumormedizin, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Berlin, Germany
    BMC Cancer 7:69. 2007
  5. ncbi request reprint Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery--a pilot study comparing coagulation profiles in infants younger than 12 months
    Bert Hildebrandt
    Medizinische Klinik m S Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13344 Berlin, Germany
    Thromb Haemost 98:172-7. 2007
  6. ncbi request reprint Regional pelvic hyperthermia as an adjunct to chemotherapy (oxaliplatin, folinic acid, 5-fluorouracil) in pre-irradiated patients with locally recurrent rectal cancer: a pilot study
    B Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Int J Hyperthermia 20:359-69. 2004
  7. ncbi request reprint Whole-body hyperthermia in the scope of von Ardenne's systemic cancer multistep therapy (sCMT) combined with chemotherapy in patients with metastatic colorectal cancer: a phase I/II study
    B Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Universitätklinikum Charité, Berlin, Germany
    Int J Hyperthermia 20:317-33. 2004
  8. ncbi request reprint Treatment of locally recurrent rectal cancer with special focus on regional pelvic hyperthermia
    B Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Onkologie 27:506-11. 2004
  9. pmc Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis - a pilot study
    B Hildebrandt
    Charité Centrum für Tumormedizin, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13344 Berlin, Germany
    BMC Cancer 7:185. 2007
  10. ncbi request reprint Current status of radiant whole-body hyperthermia at temperatures >41.5 degrees C and practical guidelines for the treatment of adults. The German 'Interdisciplinary Working Group on Hyperthermia'
    B Hildebrandt
    Medizinische Klink für Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Int J Hyperthermia 21:169-83. 2005

Detail Information

Publications56

  1. pmc Treatment with bevacizumab and FOLFOXIRI in patients with advanced colorectal cancer: presentation of two novel trials (CHARTA and PERIMAX) and review of the literature
    Alexander Stein
    University Cancer Center Hamburg, Germany
    BMC Cancer 12:356. 2012
    ..Besides multidisciplinary management further treatment intensification is warranted to improve the still limited prognosis...
  2. ncbi request reprint [Standards and perspectives in locoregional hyperthermia]
    Bert Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Berlin, Deutschland
    Wien Med Wochenschr 154:148-58. 2004
    ..We here give a critical update on the proven indications of the different locoregional hyperthermia approaches and on the current clinical and technological progress in this field...
  3. ncbi request reprint Differential gene expression in peripheral blood lymphocytes of cancer patients treated with whole body hyperthermia and chemotherapy: a pilot study
    Bert Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin der Humboldt Universität, Berlin, Germany
    Int J Hyperthermia 22:625-35. 2006
    ..The aim of this study was to identify genes that become upregulated in peripheral blood lymphocytes (PBLs) of cancer patients during a combined treatment with WBH and chemotherapy by generating complex arrays of cDNA...
  4. pmc Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: a Phase II-study and historical comparison with the surgical approach
    Bert Hildebrandt
    CharitéCentrum fur Tumormedizin, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Berlin, Germany
    BMC Cancer 7:69. 2007
    ....
  5. ncbi request reprint Intraoperative fresh-frozen plasma versus human albumin in craniofacial surgery--a pilot study comparing coagulation profiles in infants younger than 12 months
    Bert Hildebrandt
    Medizinische Klinik m S Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13344 Berlin, Germany
    Thromb Haemost 98:172-7. 2007
    ..However, the course of activation markers suggested a similar extent of clotting and fibrinolytic activation with the use of both transfusion regimens, and there were no differences with regard to clinical endpoints...
  6. ncbi request reprint Regional pelvic hyperthermia as an adjunct to chemotherapy (oxaliplatin, folinic acid, 5-fluorouracil) in pre-irradiated patients with locally recurrent rectal cancer: a pilot study
    B Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Int J Hyperthermia 20:359-69. 2004
    ..Overall toxicity was moderate, although hyperthermia may add side-effects to this approach. Results, moreover, suggest a relevant palliative effect in patients with pre-irradiated pelvic recurrence of rectal cancer...
  7. ncbi request reprint Whole-body hyperthermia in the scope of von Ardenne's systemic cancer multistep therapy (sCMT) combined with chemotherapy in patients with metastatic colorectal cancer: a phase I/II study
    B Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Universitätklinikum Charité, Berlin, Germany
    Int J Hyperthermia 20:317-33. 2004
    ..The fact that three patients who did not respond to initial chemotherapy achieved a PR after additional sCMT suggests that sCMT may enhance the effect of chemotherapy in patients with colorectal cancer...
  8. ncbi request reprint Treatment of locally recurrent rectal cancer with special focus on regional pelvic hyperthermia
    B Hildebrandt
    Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Onkologie 27:506-11. 2004
    ..Here we give a short overview on the options available for the treatment of pelvic recurrence of rectal cancer, with special focus on adjunctive regional pelvic radiofrequency hyperthermia...
  9. pmc Assessment of free light chains in the cerebrospinal fluid of patients with lymphomatous meningitis - a pilot study
    B Hildebrandt
    Charité Centrum für Tumormedizin, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13344 Berlin, Germany
    BMC Cancer 7:185. 2007
    ..Since B-cell lymphomas are clonally restricted to express either kappa or lambda immunoglobulin light chain, we hypothesised that analysis of free light chain (FLC) ratios might facilitate the diagnosis of LM...
  10. ncbi request reprint Current status of radiant whole-body hyperthermia at temperatures >41.5 degrees C and practical guidelines for the treatment of adults. The German 'Interdisciplinary Working Group on Hyperthermia'
    B Hildebrandt
    Medizinische Klink für Hämatologie und Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Int J Hyperthermia 21:169-83. 2005
    ..These recommendations may be helpful to ensure the quality of WBH performed at different institutions...
  11. ncbi request reprint Continuation of regional chemotherapy of hepatic neoplasms despite occlusion of the hepatic artery-report of four cases
    Bert Hildebrandt
    Medical Clinic for Hematology and Oncology, Campus Virchow Clinic, Charite University Hospital, 13344 Berlin, Germany
    Anticancer Drugs 13:663-9. 2002
    ..Continuation of regional chemotherapy despite hepatic arterial occlusion preserved control of intrahepatic tumor manifestations in patients who previously responded to regular HAI...
  12. ncbi request reprint Adjuvant chemotherapy with folinic acid and 5-fluorouracil in patients with locally advanced rectal cancer previously treated by preoperative radiochemotherapy and curative tumor resection
    Bert Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Charite, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Int J Colorectal Dis 21:582-9. 2006
    ..The role of postoperative adjuvant chemotherapy in patients with rectal cancer pretreated by preoperative radiochemotherapy (RCT) and curative surgery is still poorly investigated...
  13. ncbi request reprint The cellular and molecular basis of hyperthermia
    Bert Hildebrandt
    Medical Clinic, Department of Hematology and Oncology, Charite Medical School, Humboldt University, Campus Virchow Clinic, D 13344 Berlin, Germany
    Crit Rev Oncol Hematol 43:33-56. 2002
    ....
  14. pmc Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with primary liver cancer: a phase II-study (NCT00356161)
    Marianne Sinn
    CharitéCentrum fur Tumormedizin, Medizinische Klinik mit Schwerpunkt Hamatologie, Onkologie und Tumorimmunologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, D 13344 Berlin, Germany
    BMC Gastroenterol 13:125. 2013
    ..We here present an evaluation of the most important technical endpoints associated with the use of IIPCS for HAI in patients with primary liver cancers...
  15. ncbi request reprint Noninvasive magnetic resonance thermography of soft tissue sarcomas during regional hyperthermia: correlation with response and direct thermometry
    Johanna Gellermann
    Clinic for Radiation Medicine, University Hospital Charite, Campus Virchow Klinikum, Berlin, Germany
    Cancer 107:1373-82. 2006
    ..The objective of this study was to evaluate noninvasive magnetic resonance (MR) thermography for the monitoring of regional hyperthermia (RHT) in patients with soft tissue sarcomas of the lower extremities and pelvis...
  16. ncbi request reprint Fusion imaging using a hybrid SPECT-CT camera improves port perfusion scintigraphy for control of hepatic arterial infusion of chemotherapy in colorectal cancer patients
    Timm Denecke
    Campus Virchow Klinikum, Charite Universitatsmedizin Berlin Klinik fur Strahlenheilkunde und PET Zentrum Berlin, Augustenburger Platz 1 Berlin, 13353 Berlin, Germany
    Eur J Nucl Med Mol Imaging 32:1003-10. 2005
    ..The aim of this study was to evaluate port perfusion scintigraphy in colorectal cancer patients using a hybrid SPECT-CT system for control of minimally invasive intra-arterial port systems within the scope of a phase II trial...
  17. ncbi request reprint Noninvasive magnetic resonance thermography of recurrent rectal carcinoma in a 1.5 Tesla hybrid system
    Johanna Gellermann
    Clinic for Radiation Medicine, Charite Medical School, Berlin, Germany
    Cancer Res 65:5872-80. 2005
    ..Feasibility of noninvasive MR thermography for regional hyperthermia has been shown and should be further investigated...
  18. pmc Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy
    Isrid Sturm
    University Medical Center Charite, Campus Virchow Klinikum, Department of Hematology and Oncology, 13353 Berlin, Germany
    BMC Cancer 6:124. 2006
    ..e. 5-fluorouracil (5-FU), ionising gamma-radiation (IR) and heat shock/hyperthermia...
  19. ncbi request reprint Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8-42.2 degrees C
    Olaf Ahlers
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, 13344, Berlin, Germany
    Eur J Appl Physiol 95:298-306. 2005
    ..Further studies are necessary to examine the pathophysiological details and to evaluate the meaning of these transient immunological changes for patient's outcome...
  20. ncbi request reprint Dose-escalated conformal radiotherapy of glioblastomas -- results of a retrospective comparison applying radiation doses of 60 and 70 Gy
    Reinhold Graf
    Centre of Radiation Medicine, Humboldt University, Berlin, Germany
    Onkologie 28:325-30. 2005
    ..Dose escalated three-dimensional conformal radiotherapy with 70 Gy against glioblastomas was compared retrospectively with the standard scheme of 60 Gy using 2-D-planning...
  21. ncbi request reprint Radiochemotherapy combined with regional pelvic hyperthermia induces high response and resectability rates in patients with nonresectable cervical cancer > or =FIGO IIB "bulky"
    Geetha Sreenivasa
    Clinic for Radiation Medicine, Campus Virchow Klinikum, Charité Univesitätsmedizin, Berlin, Germany
    Int J Radiat Oncol Biol Phys 66:1159-67. 2006
    ..To evaluate preoperative radiochemotherapy combined with regional pelvic hyperthermia in patients with nonresectable cervical cancer >/= International Federation of Gynecology and Obstetrics (FIGO) IIB "bulky" in a Phase II study...
  22. ncbi request reprint Hepatic arterial port systems for treatment of liver metastases: factors affecting patency and adverse events
    Jens Ricke
    Department of Radiology, Charite Campus Virchow Klinikum, Humboldt University, Augustenburgerplatz 1, 13353 Berlin, Germany
    J Vasc Interv Radiol 15:825-33. 2004
    ..To assess the outcome of interventional hepatic arterial port placement in a prospective phase II trial...
  23. pmc A non-randomised, single-centre comparison of induction chemotherapy followed by radiochemotherapy versus concomitant chemotherapy with hyperfractionated radiotherapy in inoperable head and neck carcinomas
    Reinhold Graf
    Clinic for Radiation Medicine, Charite Medical School, Campus Virchow Klinikum, Augustenburger Platz, 113353 Berlin, Germany
    BMC Cancer 6:30. 2006
    ..The aim of this study was to compare the results of concomitant application of radiochemotherapy for treating locally advanced head-and-neck carcinoma in comparison with the former standard of sequential radiochemotherapy...
  24. doi request reprint Planning transarterial radioembolization of colorectal liver metastases with Yttrium 90 microspheres: evaluation of a sequential diagnostic approach using radiologic and nuclear medicine imaging techniques
    Timm Denecke
    Klinik fur Strahlenheilkunde, Bereiche Radiologie und Nuklearmedizin, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur Radiol 18:892-902. 2008
    ..Each part of the diagnostic algorithm showed a relevant impact on patient management. The sequential approach appears to be suitable and keeps the number of unnecessary treatments and therapy risks to a minimum...
  25. ncbi request reprint Whole body hyperthermia induces apoptosis in subpopulations of blood lymphocytes
    Annette Dieing
    Medical Clinic, Department of Hematology and Oncology, Charite Medical School, Humboldt University, Campus Mitte, Berlin, Germany
    Immunobiology 207:265-73. 2003
    ..Our results suggest, that apoptosis is one reason for the previously described decrease of T-cells during WBH and of NK-cells after WBH, and that the hyperthermia-related apoptosis-inducing mechanism is different in T-cells and NK-cells...
  26. ncbi request reprint Cetuximab: appraisal of a novel drug against colorectal cancer
    Bert Hildebrandt
    Centrum für Tumormedizin, Medizinische Klinik mit Schwerpunkt Hämatologie und Onkologie, Charite Campus Virchow Klinikum, Berlin, Germany
    Recent Results Cancer Res 176:135-43. 2007
    ....
  27. doi request reprint Changes in hepatic blood flow during whole body hyperthermia
    Maria Deja
    Department of Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Germany
    Int J Hyperthermia 26:95-100. 2010
    ..The aim of this clinical study was to determine changes in hepatic blood flow during WBH for the treatment of metastatic cancer...
  28. ncbi request reprint Goal-directed therapy of cardiac preload in induced whole-body hyperthermia
    Maria Deja
    Department of Anesthesiology and Critical Care Medicine, Charite Medical Center, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
    Chest 128:580-6. 2005
    ..To optimize volume therapy during induced whole-body hyperthermia (WBH) < or = 42.2 degrees C, pulmonary capillary wedge pressure (PCWP) and intrathoracic blood volume index (ITBVI) were compared as goal parameters...
  29. ncbi request reprint Influence of neoadjuvant radiochemotherapy combined with hyperthermia on the quality of life in rectum cancer patients
    T Schulze
    Department of Surgery and Surgical Oncology, Robert Rossle Klinik, Charite, Campus Buch, Universitatsmedizin Berlin, Berlin, Germany
    Int J Hyperthermia 22:301-18. 2006
    ..The present study compares quality of life (QoL) after neoadjuvant radiochemotherapy with or without hyperthermia in patients with advanced rectal cancer...
  30. ncbi request reprint Description and characterization of the novel hyperthermia- and thermoablation-system MFH 300F for clinical magnetic fluid hyperthermia
    Uwe Gneveckow
    Department of Radiation Medicine, Charite Medical School Berlin, Campus Virchow Klinikum, Center of Biomedical Nanotechnology, Spandauer Damm 130, 14050 Berlin, Germany
    Med Phys 31:1444-51. 2004
    ..01 g/l Fe in the MRI. The system has proved its capability and practicability for heat treatment in deep regions of the human body...
  31. ncbi request reprint The effect of induced hyperthermia on the immune system
    Annette Dieing
    Department of Oncology and Hematology, Charite Campus Mitte, University Medicine Berlin, Germany, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Prog Brain Res 162:137-52. 2007
    ..In this chapter, we review the most relevant data known about the effect of hyperthermia on the immune system with special focus on alterations induced by therapeutical whole-body hyperthermia (WBH) in cancer patients...
  32. ncbi request reprint Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology
    Holger Amthauer
    Klinik fur Strahlenheilkunde und PET Zentrum Berlin, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Nucl Med Mol Imaging 31:811-9. 2004
    ..FDG-PET results were statistically significant (P<0.001, CI=95%). FDG-PET has great potential in the assessment of tumour response to neoadjuvant RCT in combination with RHT and is superior to EUS for this purpose...
  33. ncbi request reprint Thermal monitoring: invasive, minimal-invasive and non-invasive approaches
    Peter Wust
    Clinic for Radiation Medicine, Charite Medical School, Campus Virchow Klinikum, Berlin, Germany
    Int J Hyperthermia 22:255-62. 2006
    ..Invasive intra-tumoural thermometry was established as a standard method several years ago. However, in deep heating, invasive techniques have disadvantages. Therefore, alternatives have been suggested and are under development...
  34. ncbi request reprint Regional hyperthermia in conjunction with definitive radiotherapy against recurrent or locally advanced prostate cancer T3 pN0 M0
    Wolfgang Tilly
    Department of Radiation Medicine, Charite Medical School, Berlin, Germany
    Strahlenther Onkol 181:35-41. 2005
    ..Since long-term results of the standard treatment of locally advanced or recurrent prostatic carcinoma are unsatisfactory, the role for additional regional hyperthermia was evaluated in a phase I/II study...
  35. doi request reprint Regional hyperthermia of the abdomen in conjunction with chemotherapy for peritoneal carcinomatosis: evaluation of two annular-phased-array applicators
    C H Cho
    Charite Universitatsmedizin Berlin, Clinic for Radiotherapy, Berlin, Germany
    Int J Hyperthermia 24:399-408. 2008
    ..In this phase I/II study, we evaluated regional hyperthermia of the pelvis and abdomen using the annular-phased-array technique as an adjunct to chemotherapy...
  36. ncbi request reprint Multislice computed tomographic angiography for preinterventional planning of port placement for intra-arterial hepatic infusion chemotherapy
    Lukas Lehmkuhl
    Clinic of Radiology, Nuclear Medicine and Radiation Oncology, Charite University Medicine Berlin, Germany
    J Comput Assist Tomogr 31:66-71. 2007
    ..To determine the impact of preinterventional multislice computed tomographic angiography (MSCTA) on the interventional management of patients scheduled for hepatic port placement...
  37. ncbi request reprint Interactions between hyperthermia and cytotoxic drugs
    B Hildebrandt
    Charité Centrum Tumormedizin, Charite Universitatsmedizin Berlin, Germany
    Cancer Treat Res 134:185-93. 2007
    ....
  38. ncbi request reprint Intraperitoneal distribution of ultrasound contrast medium imaged with B-mode ultrasound and colour-stimulated acoustic emission imaging
    R Puls
    Institut fur Radiologie, Campus Charite Mitte, Humboldt Universitat, Schumannstrasse 20 21, 10098 Berlin, Germany
    Eur Radiol 13:695-9. 2003
    ..This method is therefore well suited for imaging port catheter systems prior to chemotherapy...
  39. ncbi request reprint Assessment of local control after laser-induced thermotherapy of liver metastases from colorectal cancer: contribution of FDG-PET in patients with clinical suspicion of progressive disease
    T Denecke
    Klinik fur Strahlenheilkunde, Bereiche Radiologie und Nuklearmedizin, Medizinische Klinik mit Schwerpunkt Hämatologie Onkologie, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Acta Radiol 48:821-30. 2007
    ....
  40. ncbi request reprint Anaesthesiological experiences with whole body hyperthermia
    T Kerner
    Department of Anaesthesiology and Critical Care Medicine, Charite Medical Center, Virchow Hospital, Humboldt University, D 13344 Berlin, Germany
    Int J Hyperthermia 19:1-12. 2003
    ....
  41. ncbi request reprint A clinical pilot study of fresh frozen plasma versus human albumin in paediatric craniofacial repair
    T Kerner
    Clinic for Anaesthesiology and Intensive Care Medicine, Charité Centrum 07 for Anaesthesiology, OP Management and Intensive Care Medicine, Charite University Hospital, Berlin, Germany
    J Int Med Res 36:171-7. 2008
    ..Volume replacement during pCFS can be safely performed with both applied protocols. Our data do not demonstrate a major advantage for FFP use, but further evaluation is necessary...
  42. ncbi request reprint Hyperthermia in combined treatment of cancer
    P Wust
    Department of Radiation Oncology, Charite Medical School, Campus Virchow Klinikum, Berlin, Germany
    Lancet Oncol 3:487-97. 2002
    ..However, for every particular temperature-dependent interaction exploited for clinical purposes, sophisticated control of temperature, spatially as well as temporally, in deep body regions will further improve the potential...
  43. ncbi request reprint Monitoring arterial blood pressure during whole body hyperthermia
    T Kerner
    Department of Anesthesiology and Critical Care Medicine, Charite Medical Center, Virchow Hospital, Humboldt University, Berlin
    Acta Anaesthesiol Scand 46:561-6. 2002
    ..This investigation was performed to evaluate the agreement of invasive measurements at various sites, and to compare invasive and non-invasive methods of ABP monitoring under conditions of a heat-induced extreme vasodilation...
  44. ncbi request reprint The biologic rationale of hyperthermia
    B Hildebrandt
    Charité Centrum Tumormedizin, Charite Universitatsmedizin Berlin, Germany
    Cancer Treat Res 134:171-84. 2007
    ....
  45. ncbi request reprint Impact of overall treatment time on local control of anal cancer treated with radiochemotherapy
    R Graf
    Center of Radiation Medicine, Campus Virchow Clinic, Charite Medical School, Humboldt University, Berlin, Germany
    Oncology 65:14-22. 2003
    ....
  46. ncbi request reprint [Radiological-guided liver-port implantation: Evaluation, technical approach, interventional procedure and follow up]
    R Puls
    Klinik fur Strahlenheilkunde, Campus Virchow Klinikum, Germany
    Rofo 173:914-9. 2001
    ..Radiological-guided liver-port implantation: Evaluation, technical approach, interventional procedure and follow up...
  47. ncbi request reprint Comparison of CT, MRI and FDG-PET in response prediction of patients with locally advanced rectal cancer after multimodal preoperative therapy: is there a benefit in using functional imaging?
    T Denecke
    Klinik für Strahlenheilkunde und PET Zentrum Berlin Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany
    Eur Radiol 15:1658-66. 2005
    ..002, CT P=0.197, MRI P=0.500). These results suggest that FDG-PET is superior to CT and MRI in predicting response to preoperative multimodal treatment of locally advanced primary rectal cancer...
  48. ncbi request reprint Evaluation of patients with liver metastases from colorectal cancer for locally ablative treatment with laser induced thermotherapy. Impact of PET with 18F-fluorodeoxyglucose on therapeutic decisions
    H Amthauer
    Klinik fur Strahlenheilkunde, Charite Universitatsmedizin, Augustenburger Platz 1, 13353 Berlin, Germany
    Nuklearmedizin 45:177-84. 2006
    ..In this study we determined the value of FDG-PET in comparison to conventional staging procedures...
  49. ncbi request reprint Feasibility and analysis of thermal parameters for the whole-body-hyperthermia system IRATHERM-2000
    P Wust
    Department of Radiation Medicine, Charite Medical Center, Berlin, Germany
    Int J Hyperthermia 16:325-39. 2000
    ..In the authors' opinion, improved understanding of the mechanisms and crucial parameters underlying whole body hyperthermia, will enable a controllable and tolerable therapy through proficient contribution to equipment and methods...
  50. ncbi request reprint [Part-body hyperthermia with a radiofrequency multiantenna applicator under online control in a 1.5 T MR-tomograph]
    P Wust
    Charite, Klinik fur Strahlenheilkunde, Berlin
    Rofo 176:363-74. 2004
    ..The -hybrid approach renders development of part body hyperthermia possible as an MR-controlled intervention in radiology...
  51. ncbi request reprint Imatinib mesylate radiosensitizes human glioblastoma cells through inhibition of platelet-derived growth factor receptor
    Matthias Holdhoff
    Medizinische Klinik für Hämatologie und Onkologie, Campus Virchow, Charite, Humboldt Universitat, Augustenburger Platz 1, 13353 Berlin, Germany
    Blood Cells Mol Dis 34:181-5. 2005
    ..These results suggest that imatinib may have clinical utility as a radiosensitizer in the treatment of human glioblastoma, possibly through disruption of an autocrine PDGF/PDGFR loop...
  52. ncbi request reprint Repetitive transarterial chemoembolization (rTACE) of hepatocellular carcinoma: comparisons between an arterial port system and conventional angiographic technique
    Nico Hidajat
    Department of Radiology, Charite, Virchow Clinic of the Humboldt University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Radiol 51:6-11. 2004
    ..To compare the cost and radiation exposure of repetitive transarterial chemoembolization (rTACE) using percutaneously implantable port system with rTACE using conventional catheterization technique...
  53. ncbi request reprint Effective use of high-dose chemotherapy and autologous stem cell rescue for relapsed adult Wilms' tumor and a novel alteration in intron 1 of the WT1 gene
    Ralf Ulrich Trappe
    Department of Hematology and Oncology, Charite University Hospital Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, D 13353 Berlin, Germany
    J Pediatr Hematol Oncol 26:820-3. 2004
    ..Both chemotherapy regimens showed moderate treatment-related toxicity. This report is the first that indicates that adult nephroblastoma patients also may carry WT1 germline mutations...
  54. ncbi request reprint Methods and potentials of magnetic resonance imaging for monitoring radiofrequency hyperthermia in a hybrid system
    J Gellermann
    Department of Radiation Medicine, Charite Medical School, Berlin, Germany
    Int J Hyperthermia 21:497-513. 2005
    ..A hybridization of an MRI scanner with a hyperthermia system is necessary for a real-time NIT. The selection of the best thermographic method is difficult, because many parameters and attributes have to be considered...
  55. ncbi request reprint Hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinosis
    Bert Hildebrandt
    J Clin Oncol 22:1527-9; author reply 1529. 2004
  56. ncbi request reprint 5-fluorouracil, folinic acid and oxaliplatin administered via hepatic arterial infusion as regional second-line therapy for advanced colorectal cancer
    Lars Meyer
    Oncology 64:473-4. 2003