Andreas Heinz

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving
    Andreas Heinz
    Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    Am J Psychiatry 161:1783-9. 2004
  2. doi Paliperidone-ER: first atypical antipsychotic with oral extended release formulation
    Marion Lautenschlager
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Expert Rev Neurother 8:193-200. 2008
  3. ncbi Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Nat Neurosci 8:20-1. 2005
  4. doi Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Schizophr Res 118:189-200. 2010
  5. ncbi Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 196:673-84. 2008
  6. doi 5-HTT genotype effect on prefrontal-amygdala coupling differs between major depression and controls
    Eva Friedel
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 205:261-71. 2009
  7. doi Switching schizophrenia patients from typical neuroleptics to olanzapine: effects on BOLD response during attention and working memory
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Eur Neuropsychopharmacol 18:589-99. 2008
  8. doi Dopamine in amygdala gates limbic processing of aversive stimuli in humans
    Thorsten Kienast
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Neurosci 11:1381-2. 2008
  9. doi Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany
    Neuropsychobiology 66:50-6. 2012
  10. ncbi Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center Berlin, CCM, Berlin, Germany
    Alcohol Clin Exp Res 31:1138-47. 2007

Collaborators

Detail Information

Publications116 found, 100 shown here

  1. ncbi Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving
    Andreas Heinz
    Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    Am J Psychiatry 161:1783-9. 2004
    ..Prolonged D(2) receptor dysfunction in the ventral striatum may interfere with a dopamine-dependent error detection signal and bias the brain reward system toward excessive attribution of incentive salience to alcohol-associated stimuli...
  2. doi Paliperidone-ER: first atypical antipsychotic with oral extended release formulation
    Marion Lautenschlager
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Expert Rev Neurother 8:193-200. 2008
    ..The OROS-ER technology leads to considerably lower plasma peak levels compared with nonextended-release formulations, thus possibly reducing side effects...
  3. ncbi Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Nat Neurosci 8:20-1. 2005
    ..s carriers also showed greater coupling between the amygdala and the ventromedial prefrontal cortex, which may contribute to the abnormally high activity in the amygdala and medial prefrontal cortex seen in major depression...
  4. doi Switching schizophrenia patients from typical neuroleptics to aripiprazole: effects on working memory dependent functional activation
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Schizophr Res 118:189-200. 2010
    ..However, little is known about specific medication effects on the modulation of frontal activation during WM performance...
  5. ncbi Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 196:673-84. 2008
    ..This may not be the case with newer neuroleptics such as olanzapine, which show less dopamine D2 receptor blockade and a faster off-rate from the receptor...
  6. doi 5-HTT genotype effect on prefrontal-amygdala coupling differs between major depression and controls
    Eva Friedel
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 205:261-71. 2009
    ..This prefrontal-limbic interaction has been shown to be modulated by serotonin (5-HTT) genotype, indicating a higher risk for major depressive disorder (MDD) with increasing number of 5-HTT low-expression alleles...
  7. doi Switching schizophrenia patients from typical neuroleptics to olanzapine: effects on BOLD response during attention and working memory
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Eur Neuropsychopharmacol 18:589-99. 2008
    ..However, medication status had influences on the activation during attentional task (0-back), emphasizing the importance of baseline selection in pharmacological fMRI studies...
  8. doi Dopamine in amygdala gates limbic processing of aversive stimuli in humans
    Thorsten Kienast
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Neurosci 11:1381-2. 2008
    ..Our results suggest that individual dopamine storage capacity in amygdala subserves modulation of emotional processing in amygdala and dorsal cingulate, thereby contributing to individual differences in anxious temperament...
  9. doi Ventral striatal activation during reward processing in subjects with ultra-high risk for schizophrenia
    Georg Juckel
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Bochum, Germany
    Neuropsychobiology 66:50-6. 2012
    ....
  10. ncbi Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center Berlin, CCM, Berlin, Germany
    Alcohol Clin Exp Res 31:1138-47. 2007
    ..We assessed whether brain activation elicited by (1) alcohol associated, (2) affectively positive, and (3) negative versus neutral stimuli is associated with the subsequent risk of relapse...
  11. doi Reduction of auditory event-related P300 amplitude in subjects with at-risk mental state for schizophrenia
    Seza Ozgurdal
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Germany
    Schizophr Res 105:272-8. 2008
    ..e. before a manifestation of full-blown psychosis, and that these changes seem to have a progressive course from prodromal to chronic state of schizophrenia as assumed in this cross-sectional study...
  12. ncbi Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charité Mitte CCM, Schumannstr 20 21, Berlin 10117, Germany
    Psychopharmacology (Berl) 187:222-8. 2006
    ..Dysfunction of the dopaminergic reward system may contribute to negative symptoms in schizophrenia...
  13. pmc Hippocampal subdivision and amygdalar volumes in patients in an at-risk mental state for schizophrenia
    Henning Witthaus
    Early Recognition and Therapy Centre for Beginning Psychoses Bochum, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Bochum, Germany
    J Psychiatry Neurosci 35:33-40. 2010
    ..Furthermore, no subregions of the hippocampus have been investigated in people at UHR...
  14. doi Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics
    Anne Beck
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Biol Psychiatry 66:734-42. 2009
    ..We explored whether functional brain activation during anticipation of incentive stimuli is associated with impulsiveness in detoxified alcoholics and healthy control subjects...
  15. pmc Dopaminergic dysfunction in schizophrenia: salience attribution revisited
    Andreas Heinz
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, 10117 Berlin, Germany
    Schizophr Bull 36:472-85. 2010
    ....
  16. ncbi Serotonin transporter genotype (5-HTTLPR): effects of neutral and undefined conditions on amygdala activation
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Germany
    Biol Psychiatry 61:1011-4. 2007
    ..However, a recent report suggested that this interaction is driven by amygdala deactivation during presentation of neutral stimuli in s carriers...
  17. pmc Ventral striatal prediction error signaling is associated with dopamine synthesis capacity and fluid intelligence
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany
    Hum Brain Mapp 34:1490-9. 2013
    ....
  18. doi Catechol-O-methyltransferase val158met genotype influences neural processing of reward anticipation
    Katharina Schmack
    Department of Psychiatry, Charite University Medicine, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 42:1631-8. 2008
    ..Current evidence and our results are compatible with an interpretation that construes this effect of COMT genotype on striatal reactivity as a result of a cortico-striatal interaction...
  19. doi Context insensitivity during positive and negative emotional expectancy in depression assessed with functional magnetic resonance imaging
    Melanie Feeser
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 212:28-35. 2013
    ..This hyporeactivity may contribute to clinical features like anergia, apathy, and loss of motivation in the context of both positive and negative incentives...
  20. doi Hyporeactivity of ventral striatum towards incentive stimuli in unmedicated depressed patients normalizes after treatment with escitalopram
    Meline Stoy
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:677-88. 2012
    ..These findings suggest that MDD patients show ventral striatal hyporesponsiveness during incentive cue processing, which normalizes after successful treatment...
  21. doi Subtle deficits of cognitive theory of mind in unaffected first-degree relatives of schizophrenia patients
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Germany
    Eur Arch Psychiatry Clin Neurosci 262:217-26. 2012
    ..Findings corroborate the assumption of distinct social-cognitive abilities as an intermediate phenotype for schizophrenia...
  22. doi Neurocognitive performances in participants of at-risk mental state for schizophrenia and in first-episode patients
    Seza Ozgurdal
    Early Recognition and Therapy Centre for Beginning Psychoses Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Bochum, Germany
    J Clin Exp Neuropsychol 31:392-401. 2009
    ..Results suggest that high-risk participants do perform at average neurocognitive performance levels at all tested domains compared with normative data. Compared to norm values first-episode patients showed decreased attention abilities...
  23. doi Childhood methylphenidate treatment of ADHD and response to affective stimuli
    Lorna Schlochtermeier
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Eur Neuropsychopharmacol 21:646-54. 2011
    ..Further prospective studies need to clarify direct and indirect mechanisms of MPH treatment that may contribute to emotional processing, which is dysfunctional in males without pharmacological treatment in childhood...
  24. doi Gray matter abnormalities in subjects at ultra-high risk for schizophrenia and first-episode schizophrenic patients compared to healthy controls
    Henning Witthaus
    Early Recognition and Therapy Centre for Psychoses Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Alexandrinenstrasse 1, 44791, Germany
    Psychiatry Res 173:163-9. 2009
    ..This study provides further evidence that gray matter brain volume, especially in the anterior cingulate cortex, is already reduced in the prodromal state of schizophrenia...
  25. doi Test-performance after cognitive training in persons at risk mental state of schizophrenia and patients with schizophrenia
    Stephan Rauchensteiner
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Germany
    Psychiatry Res 185:334-9. 2011
    ..These results should be confirmed by further investigations including larger sample sizes...
  26. ncbi Different neural systems adjust motor behavior in response to reward and punishment
    Jana Wrase
    Department of Psychiatry, Charité Universitätsmedizin Berlin Charité Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 36:1253-62. 2007
    ..Our results provide evidence that different but somewhat overlapping circuits mediate the same behavioral adaptation when it is driven by different incentive outcomes...
  27. doi Functional neuroanatomy of emotion processing in major depressive disorder is altered after successful antidepressant therapy
    Gabriela Rosenblau
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:1424-33. 2012
    ..These findings show that the neural mechanisms of emotion anticipation and processing are altered in patients with MDD and that these alterations are able to normalize after treatment with an antidepressant...
  28. doi Decline in prefrontal catecholamine synthesis explains age-related changes in cognitive speed beyond regional grey matter atrophy
    Jan Kalbitzer
    Department of Psychiatry and Psychotherapy, Campus Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Eur J Nucl Med Mol Imaging 39:1462-6. 2012
    ..Age-related decline in cognitive speed has been associated with prefrontal dopamine D1 receptor availability, but the contribution of presynaptic dopamine and noradrenaline innervation to age-related changes in cognition is unknown...
  29. ncbi Correlation of stable elevations in striatal mu-opioid receptor availability in detoxified alcoholic patients with alcohol craving: a positron emission tomography study using carbon 11-labeled carfentanil
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    Arch Gen Psychiatry 62:57-64. 2005
    ..Blockade of mu-opiate receptors with naltrexone reduces the relapse risk among some but not all alcoholic individuals...
  30. doi Lesion of the medial prefrontal cortex and the subthalamic nucleus selectively affect depression-like behavior in rats
    Julia Klein
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Behav Brain Res 213:73-81. 2010
    ....
  31. ncbi Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics
    Sabine M Grüsser
    Department of Medical Psychology, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Psychopharmacology (Berl) 175:296-302. 2004
    ..Animal experiments have provided evidence that the striatum and medial prefrontal cortex play a predominant role in the acquisition and maintenance of drug-seeking behavior...
  32. doi Apparent motion perception in patients with paranoid schizophrenia
    Lia Lira Olivier Sanders
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 263:233-9. 2013
    ..These results suggest that schizophrenia may be associated with a reduced susceptibility to visual phenomena that commonly rely on perceptual inference...
  33. doi Neurobiological correlates of delusion: beyond the salience attribution hypothesis
    Anne Pankow
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuropsychobiology 66:33-43. 2012
    ..Neuroleptic medication, on the other hand, appears to interfere with anticipation of reward in the ventral striatum and can thus contribute to secondary negative symptoms such as apathy and avolition...
  34. ncbi Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Biol Psychiatry 62:1295-302. 2007
    ..This study investigates the association of the GSK3B -50T/C SNP and response to lithium augmentation in acutely depressed antidepressant nonresponders...
  35. doi Different aspects of theory of mind in paranoid schizophrenia: evidence from a video-based assessment
    Christiane Montag
    Charite University Medicine Berlin, Department of Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany
    Psychiatry Res 186:203-9. 2011
    ..In schizophrenic patients, negative symptoms were associated with a lack of a mental state concept, while positive symptoms like delusions were associated with 'overmentalizing', supporting respective etiological concepts of delusions...
  36. doi Efficacy and safety of pregabalin in the treatment of alcohol withdrawal syndrome: a randomized placebo-controlled trial
    Anna Förg
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, D 10117 Berlin, Germany
    Alcohol Alcohol 47:149-55. 2012
    ..The objective of this study was to collect preliminary data on the efficacy and safety of pregabalin in attenuating the severity of alcohol withdrawal symptoms during detoxification treatment in alcohol dependence...
  37. doi Reduced prefrontal-parietal effective connectivity and working memory deficits in schizophrenia
    Lorenz Deserno
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, 10117 Berlin, Germany
    J Neurosci 32:12-20. 2012
    ..Moreover, this study in a large sample of patients reveals a mechanism underlying prefrontal inefficiency and cognitive deficits in schizophrenia, thereby providing direct experimental evidence for the dysconnectivity hypothesis...
  38. doi The acute antipanic and anxiolytic activity of aerobic exercise in patients with panic disorder and healthy control subjects
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Psychiatr Res 43:1013-7. 2009
    ..These findings suggest that in addition to exercise training an acute bout of exercise may be used to reduce anxiety and panic attack frequency and intensity in panic disorder patients...
  39. doi Amygdala volume associated with alcohol abuse relapse and craving
    Jana Wrase
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:1179-84. 2008
    ..This study sought an association in alcohol-dependent subjects between volumes of reward-related brain regions, alcohol craving, and the risk of relapse...
  40. doi Three cases of successful tryptophan add-on or monotherapy of hepatitis C and IFNalpha-associated mood disorders
    Martin Schaefer
    Department of Psychiatry, Charite Universitatsmedizin, Berlin, Germany
    Psychosomatics 49:442-6. 2008
    ..Interferon-alpha (IFN(alpha))-associated mood disorder is a major complication of treatment for chronic hepatitis C...
  41. ncbi Serotonergic dysfunction: brain imaging and behavioral correlates
    Jana Wrase
    Charite University Medicine Berlin, Berlin, Germany
    Cogn Affect Behav Neurosci 6:53-61. 2006
    ..Animal experiments point to a relationship between serotonergic dysfunction, negative mood states, and excessive alcohol intake, which may in part be mediated by reduced alcohol-induced sedation...
  42. doi Detection of visual events along the apparent motion trace in patients with paranoid schizophrenia
    Lia Lira Olivier Sanders
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 198:216-23. 2012
    ....
  43. ncbi Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence
    Andreas Heinz
    Department of Psychiatry, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 174:561-70. 2004
    ..The severity and time-course of recovery of these neuroadaptive changes may depend on the genetic constitution of monoamine transporters and receptors and contribute to the relapse risk of alcoholics...
  44. ncbi Reward anticipation and outcomes in adult males with attention-deficit/hyperactivity disorder
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Neuroimage 39:966-72. 2008
    ..These findings suggest that male adults with ADHD show neural signs of abnormal reward processing. Future studies will have to investigate whether these dysfunctional patterns might be normalized by treatment...
  45. ncbi Gender differences in the processing of standardized emotional visual stimuli in humans: a functional magnetic resonance imaging study
    Jana Wrase
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    Neurosci Lett 348:41-5. 2003
    ..These results indicate that it is crucial to take gender differences into account when emotional paradigms are used in functional brain imaging...
  46. doi White matter abnormalities in subjects at ultra high-risk for schizophrenia and first-episode schizophrenic patients
    Henning Witthaus
    Early Recognition and Therapy Centre for beginning psychosis Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, 44791 Bochum, Germany
    Schizophr Res 102:141-9. 2008
    ..Furthermore, white matter abnormalities seem to progress after transition into schizophrenia...
  47. doi Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons
    Kathrin Scheuch
    Neuropsychiatry and Laboratory of Molecular Psychiatry, Charite Universitatsmedizin Berlin, 10117 Berlin, Germany
    Brain Res 1307:14-21. 2010
    ..Our results suggest that lithium can modify tph2 gene expression and 5-HT release in raphe neurons, providing new insight into the serotonergic mechanisms of action of lithium...
  48. doi Dietrich Bonhoeffer (1906-1945)
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:577-8. 2008
  49. ncbi Prevention of interferon-alpha associated depression in psychiatric risk patients with chronic hepatitis C
    Martin Schaefer
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, D 10117 Berlin, Germany
    J Hepatol 42:793-8. 2005
    ..We prospectively studied the efficacy of a pre-emptive treatment with the antidepressant citalopram to prevent depression during hepatitis C treatment with pegylated IFN-alpha-2b plus ribavirin...
  50. doi Sense of agency is altered in patients with a putative psychotic prodrome
    Marta Hauser
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Schizophr Res 126:20-7. 2011
    ..e. in patients with a putative psychotic prodrome (PP). Previous research has shown that time judgments of voluntary actions can provide an implicit measure of the SoAg...
  51. doi Escitalopram for the prevention of peginterferon-α2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial
    Martin Schaefer
    Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen Mitte, Henricistr 92, 45136 Essen, Germany
    Ann Intern Med 157:94-103. 2012
    ..It is unclear whether antidepressants can prevent IFN-induced depression in patients without psychiatric risk factors...
  52. doi Exercise and physical activity in mental disorders
    Elisabeth Wolff
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 261:S186-91. 2011
    ..Mechanisms of the therapeutic effects of EX/PA are summarized, including metabolic and physiological as well as psychological aspects. Finally, implications for research and therapeutic practice are illustrated...
  53. doi Theodor Lipps and the concept of empathy: 1851-1914
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Psychiatric University Hospital at St Hedwig Krankenhaus, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:1261. 2008
  54. pmc Prefrontal cortex glutamate correlates with mental perspective-taking
    Christiane Montag
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Mitte, Berlin, Germany
    PLoS ONE 3:e3890. 2008
    ..However, the role of the glutamate system for different dimensions of empathy has not been investigated so far...
  55. doi Theory of mind impairments in euthymic bipolar patients
    Christiane Montag
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Affect Disord 123:264-9. 2010
    ..In bipolar affective disorder, evidence for ToM deficits is scant, although brain imaging studies and impairments in non-social neurocognitive domains indicate deficits of prefrontal functions...
  56. doi Loudness dependence of auditory evoked potentials as indicator of central serotonergic neurotransmission: simultaneous electrophysiological recordings and in vivo microdialysis in the rat primary auditory cortex
    Alexander Wutzler
    Department of Psychiatry, Charite, Mitte, Berlin, Germany
    Neuropsychopharmacology 33:3176-81. 2008
    ..86, p=0.003). These data support the view that the LDAEP is closely modulated by cortical serotonergic activity. Thus, the LDAEP might serve as an inversely related marker of synaptically released serotonin in the CNS...
  57. ncbi The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center, Campus Mitte, Berlin, Germany
    Rev Neurosci 17:359-67. 2006
    ..Thus the met158 allele seems to be beneficial during the performance of working memory and attention-related tasks, whereas the val158 allele appears to be advantageous during the processing of aversive emotional stimuli...
  58. ncbi Is dose escalation of antidepressants a rational strategy after a medium-dose treatment has failed? A systematic review
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Germany
    Eur Arch Psychiatry Clin Neurosci 255:387-400. 2005
    ..e. augmentation or change of compound) are lacking. The aim of this publication is to review available direct and indirect evidence concerning dose increase of antidepressants after a medium-dose trial has failed...
  59. doi Altered representation of expected value in the orbitofrontal cortex in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Hum Brain Mapp 31:958-69. 2010
    ..Here we studied neural correlates of gain and loss expectation in mania using functional magnetic resonance imaging (fMRI)...
  60. ncbi The acute antipanic activity of aerobic exercise
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Am J Psychiatry 162:2376-8. 2005
    ..Regular physical activity is anxiolytic for both healthy subjects and patients with panic disorder. However, the acute antipanic activity of exercise has not yet been studied systematically...
  61. doi [Pharmacotherapy of neuropsychiatric symptoms in dementia in nursing homes: a comparison of service provision by psychiatric outpatient clinics and primary care psychiatrists]
    Michael A Rapp
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Berlin
    Psychiatr Prax 37:196-8. 2010
    ..The aim of this study was to test whether the severity and pharmacotherapy differed in patients treated by outpatient clinics at psychiatric hospitals, as compared to primary care specialists...
  62. pmc Identifying the neural circuitry of alcohol craving and relapse vulnerability
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Charité Mitte, Germany
    Addict Biol 14:108-18. 2009
    ..These findings are discussed with respect to psychotherapeutic and pharmacological treatment options...
  63. doi Reward feedback alterations in unmedicated schizophrenia patients: relevance for delusions
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Germany
    Biol Psychiatry 65:1032-9. 2009
    ..Increased attribution of incentive salience to neutral or aversive stimuli might be associated with dysfunction of neuronal processing of positive and negative reinforcement and contribute to the formation of delusions in schizophrenia...
  64. doi A model comparison of COMT effects on central processing of affective stimuli
    Imke Puls
    Department of Psychiatry and Psychotherapy CCM, Charite University Medical Center, D 10117 Berlin, Germany
    Neuroimage 46:683-91. 2009
    ....
  65. doi Attentional modulation of emotional stimulus processing in patients with major depression--alterations in prefrontal cortical regions
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neurosci Lett 463:108-13. 2009
    ..Altered prefrontal modulation in depression may contribute to impaired affect modulation and related clinical symptoms, such as anhedonia...
  66. ncbi Hepatitis C treatment in "difficult-to-treat" psychiatric patients with pegylated interferon-alpha and ribavirin: response and psychiatric side effects
    Martin Schaefer
    Charite Universitatsmedizin Berlin, Klinik und Poliklinik für Psychiatrie und Psychotherapie Campus Charité Mitte, Berlin, Germany
    Hepatology 46:991-8. 2007
    ....
  67. doi Pharmacoepidemiology of patients hospitalized for somatoform disorders in psychiatric hospitals and departments
    Adrian Mundt
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Universitatsmedizin Berlin, Germany
    Pharmacoepidemiol Drug Saf 19:687-93. 2010
    ..We evaluated the current pharmacological treatment strategies used for psychiatric in-patients diagnosed with SD in Central Europe...
  68. ncbi Genetic research with intermediate phenotypes: phenocopies, perspectives and pitfalls
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medical Center Berlin, Charite Campus Mitte, Berlin, Germany
    Addiction 102:1696-7. 2007
  69. ncbi Therapy and supportive care of alcoholics: guidelines for practitioners
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    Best Pract Res Clin Gastroenterol 17:695-708. 2003
    ..If adequate treatment is available, relapse rates were as low as 50% in those follow-up studies that examined treatment periods of up to 2 years, so that there is no justification for therapeutic nihilism...
  70. ncbi [Genetic and pharmacological effects on prefrontal cortical function in schizophrenia]
    Andreas Heinz
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin
    Nervenarzt 75:845-56. 2004
    ..Molecular brain imaging combines imaging techniques with the assessment of genotype effects and represents a powerful tool for the understanding of neuropsychiatric disorders...
  71. doi Cultural factors in the diagnosis and treatment of traumatised migrant patients from Turkey
    Meryam Schouler-Ocak
    Psychiatric University Hospital St Hedwig, Charite, Berlin, Germany
    Transcult Psychiatry 45:652-70. 2008
    ..In the following paper, we consider the unique aspects of trauma-focused psychotherapy in patients with a history of migration. We discuss a variety of culture-specific factors with the help of two case histories...
  72. doi [Psychotherapy with traumatised migrants from Turkey: taking into account cultural factors]
    Meryam Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus, Grosse Hamburger Strasse 5 11, 10115 Berlin, Germany
    Psychother Psychosom Med Psychol 58:169-75. 2008
    ..The influence of culture-specific factors on trauma-focussed psychotherapy is being discussed...
  73. doi [Patients of immigrant origin in outpatient psychiatric facilities: a comparison between Turkish, eastern European and German patients]
    Meryam Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus Berlin, Berlin
    Psychiatr Prax 37:384-90. 2010
    ..Nationwide representative survey of the use of psychiatric outpatient services in Germany...
  74. doi Altered awareness of action in schizophrenia: a specific deficit in predicting action consequences
    Martin Voss
    Department of Psychiatry and Psychotherapy, Charite University Hospital, St Hedwig Hospital, Grosse Hamburger Strasse 5 11, Berlin, Germany
    Brain 133:3104-12. 2010
    ..The failure to predict the effects of one's own actions may underlie the blurring and confusion in the relationship between the self and the world that characterizes acute psychosis...
  75. doi Karl Bonhoeffer (1868-1948)
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Am J Psychiatry 165:575-6. 2008
  76. ncbi Therapy and supportive care of alcoholics: guidelines for practitioners
    Thorsten Kienast
    Department of Psychiatry, Charite, University Medical Center, Campus Mitte, Berlin, Germany
    Dig Dis 23:304-9. 2005
    ..Moreover, the concept can be quickly and easily integrated into the daily routine of any therapeutic team...
  77. ncbi Early recognition of bipolar disorder
    Marta Hauser
    Early Recognition Center of Beginning Psychoses, Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    Eur Psychiatry 22:92-8. 2007
    ..This will require prospective studies to determine the predictive power of the risk factors integrated into the scale...
  78. doi Activity modulation of the globus pallidus and the nucleus entopeduncularis affects compulsive checking in rats
    Anaïs Djodari-Irani
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Behav Brain Res 219:149-58. 2011
    ....
  79. ncbi Immigration-associated variables and substance dependence
    Sabine M Grüsser
    Institute for Medical Psychology, Center for Humanities and Health Sciences, Charite University Medicine Berlin, Tucholskystrasse 2, 10117 Berlin, Germany
    J Stud Alcohol 66:98-104. 2005
    ....
  80. doi Adjunct treatment with levodopa in a patient with dementia with Lewy bodies, delusions and severe neuroleptic hypersensitivity syndrome
    Tomislav Majic
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, 10117 Berlin, Germany
    Int Psychogeriatr 22:678-9. 2010
    ..After treating the patient with levodopa and clozapine, these symptoms remitted...
  81. ncbi Treatment of chronic hepatitis C in patients with drug dependence: time to change the rules?
    Martin Schaefer
    Department of Psychiatry CCM, Charite University Medicine Berlin, Berlin, Germany
    Addiction 99:1167-75. 2004
    ....
  82. ncbi Psychiatric symptoms and cognitive dysfunction caused by Epstein-Barr virus-induced encephalitis
    Joachim Behr
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Eur Psychiatry 21:521-2. 2006
    ..Clinical recovery and clearance of cerebrospinal fluid EBV DNA appeared following ganciclovir treatment within 6 weeks...
  83. ncbi Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Shumannstrasse 20 21, 10117 Berlin, Germany
    Neuropsychopharmacology 32:2098-107. 2007
    ..Our findings further suggest that CB1 receptor antagonism may be involved in restoring disturbed interactions between the activity of the endocannabinoid system and glutamate neurotransmitter system implied in schizophrenia...
  84. doi A combination of levetiracetam and tiapride for outpatient alcohol detoxification: a case series
    Christian A Müller
    Department of Psychiatry, Universitatsmedizin Berlin, Berlin, Germany
    J Addict Med 5:153-6. 2011
    ..The aim of this evaluation was to examine the efficacy and tolerability of a combination of levetiracetam and tiapride for outpatient alcohol detoxification...
  85. ncbi Dysfunction of ventral striatal reward prediction in schizophrenia
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charite Mitte, CCM, Schumannstr 20 21, 10117 Berlin, Germany
    Neuroimage 29:409-16. 2006
    ..We used functional magnetic resonance imaging (fMRI) to assess the BOLD response in the ventral striatum of unmedicated schizophrenics during presentation of reward-indicating and loss-indicating stimuli...
  86. doi A comparison of three scores to screen for delirium on the surgical ward
    Finn M Radtke
    Department of Anesthesiology and Surgical Intensive Care Medicine, Campus Charite Mitte, Charite Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    World J Surg 34:487-94. 2010
    ..Postoperative delirium is associated with adverse outcome. The aim of this study was to find a valid and easy-to-use tool to screen for postoperative delirium on the surgical ward...
  87. ncbi Anxiety modulation by the heart? Aerobic exercise and atrial natriuretic peptide
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychoneuroendocrinology 31:1127-30. 2006
    ..Our results suggest that besides other mechanisms, ANP might be a physiologically relevant humoral link between the heart and anxiety-related behavior contributing to the acute anxiolytic effects of exercise...
  88. pmc Understanding left-handedness
    Stefan Gutwinski
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Grosse Hamburger Str 5 11, 10115 Berlin, Germany
    Dtsch Arztebl Int 108:849-53. 2011
    ..Recent epidemiological and neurobiological research has shed new light on the development of the cerebral lateralization of motor processes, including handedness. In this article, we present these findings from a medical perspective...
  89. ncbi Lithium augmentation therapy in refractory depression: clinical evidence and neurobiological mechanisms
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Hospital, Humboldt University at Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Can J Psychiatry 48:440-8. 2003
    ..It also examines hypotheses on the mode of action of lithium augmentation, with a focus on serotonin (5-HT) and neuroendocrine systems, and proposes recommendations for future research...
  90. ncbi Effects of acute psychological stress on adhesion molecules, interleukins and sex hormones: implications for coronary heart disease
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 165:111-7. 2003
    ..Cell adhesion molecules may be activated by psychological stress exposure, depending on their interaction with the interleukin network, sex hormones and cortisol secretion...
  91. doi Neural markers of genetic vulnerability to drug addiction
    Daniel J Muller
    Department of Psychiatry, Charite University Medicine, Campus Charite Mitte, Schumannstrasse, Berlin, Germany
    Curr Top Behav Neurosci 3:277-99. 2010
    ..In conclusion, we provide the reader with an overview of most important studies related to AD and ND and give an outlook how these findings may become useful and beneficial in the future...
  92. pmc Hippocampal morphology and distinguishing late-onset from early-onset elderly depression
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin
    Am J Psychiatry 165:229-37. 2008
    ..This study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. Neuropsychological correlates of hippocampal morphology were also investigated...
  93. ncbi Dysregulation of the hypothalamic-pituitary-thyroid axis in alcoholism
    Derik Hermann
    Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Addiction 97:1369-81. 2002
    ..We discuss further additional effects of alcohol on thyroid-hormone metabolizing deiodinases and on monoaminergic systems, which may interact directly with mood states among abstinent alcoholics...
  94. ncbi Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex
    Michael N Smolka
    Central Institute of Mental Health, 68159 Mannheim, Germany
    J Neurosci 25:836-42. 2005
    ....
  95. doi Ratio of dopamine synthesis capacity to D2 receptor availability in ventral striatum correlates with central processing of affective stimuli
    Thorsten Kienast
    Department of Psychiatry and Psychotherapy of the Charité University Medical Center, Charite Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Eur J Nucl Med Mol Imaging 35:1147-58. 2008
    ..We investigated the dopaminergic neurotransmission in the ventral and dorsal striatum with respect to central processing of affective stimuli in healthy subjects...
  96. ncbi The startle reflex in alcohol-dependent patients: changes after cognitive-behavioral therapy and predictive validity for drinking behavior. A pilot study
    Sabine Loeber
    Department of Addictive Behavior and Addiction Medicine, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
    Psychother Psychosom 76:385-90. 2007
    ..Further, we examined whether the affect-modulated startle reflex is a predictor of treatment success...
  97. ncbi Glucose utilization in the medial prefrontal cortex correlates with serotonin turnover rate and clinical depression in alcoholics
    Wendol Williams
    National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    Psychiatry Res 132:219-24. 2004
    ..This pilot study indicates that a dysfunction of medial PFC may interact with central serotonin turnover and negative mood states during early abstinence...
  98. ncbi Reward craving and withdrawal relief craving: assessment of different motivational pathways to alcohol intake
    Andreas Heinz
    Department of Addictive Behaviour and Addiction Medicine, Humboldt University, Berlin, Germany
    Alcohol Alcohol 38:35-9. 2003
    ....
  99. ncbi DASB -in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer
    René Hummerich
    Biochemical Laboratory, Central Institute of Mental Health, Mannheim, Germany
    J Neurochem 90:1218-26. 2004
    ..4 nm). These findings suggest DASB to be a highly selective PET tracer to visualize the density of serotonergic synapses in human brain...
  100. ncbi Huntington's disease: phenomenological diversity of a neuropsychiatric condition that challenges traditional concepts in neurology and psychiatry
    Heike Tost
    Central Institute of Mental Health, University of Heidelberg, Germany
    Am J Psychiatry 161:28-34. 2004
  101. ncbi Reduced fMRI activation of an occipital area in recently detoxified alcohol-dependent patients in a visual and acoustic stimulation paradigm
    Derik Hermann
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 12:117-21. 2007
    ..Attention deficits or a persisting neuronal alteration in the first weeks of alcohol abstinence may have contributed to this result...