A Heinz

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Therapy and supportive care of alcoholics: guidelines for practitioners
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    Best Pract Res Clin Gastroenterol 17:695-708. 2003
  2. ncbi request reprint The influence of gender and emotional valence of visual cues on FMRI activation in humans
    S Klein
    Central Institute of Mental Health, Mannheim, Germany
    Pharmacopsychiatry 36:S191-4. 2003
  3. doi request reprint Neurotransmitter systems in alcohol dependence
    A Heinz
    Department of Psychiatry and Psychotherapy, CCM, Charite University Medicine, Berlin, Germany
    Pharmacopsychiatry 42:S95-S101. 2009
  4. doi request reprint Construction and interpretation of self-related function and dysfunction in Intercultural Psychiatry
    A Heinz
    Department of Psychiatry and Psychotherapy, Charite Berlin, Germany
    Eur Psychiatry 27:S32-43. 2012
  5. ncbi request reprint Serotonin transporter availability correlates with alcohol intake in non-human primates
    A Heinz
    Clinical Brain Disorders Branch, NIMH NIH, Bethesda, MD, USA
    Mol Psychiatry 8:231-4. 2003
  6. ncbi request reprint [Thujon and absinthe--a historical misperception?]
    A Heinz
    Universitatsklinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Fortschr Neurol Psychiatr 75:309-10. 2007
  7. ncbi request reprint Genetic research with intermediate phenotypes: phenocopies, perspectives and pitfalls
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medical Center Berlin, Charite Campus Mitte, Berlin, Germany
    Addiction 102:1696-7. 2007
  8. ncbi request reprint Neurobiological correlates of the disposition and maintenance of alcoholism
    A Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S255-8. 2003
  9. ncbi request reprint [Genetic and pharmacological effects on prefrontal cortical function in schizophrenia]
    Andreas Heinz
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin
    Nervenarzt 75:845-56. 2004
  10. ncbi request reprint The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center, Campus Mitte, Berlin, Germany
    Rev Neurosci 17:359-67. 2006

Collaborators

Detail Information

Publications150 found, 100 shown here

  1. ncbi request reprint Therapy and supportive care of alcoholics: guidelines for practitioners
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    Best Pract Res Clin Gastroenterol 17:695-708. 2003
    ..If adequate treatment is available, relapse rates were as low as 50% in those follow-up studies that examined treatment periods of up to 2 years, so that there is no justification for therapeutic nihilism...
  2. ncbi request reprint The influence of gender and emotional valence of visual cues on FMRI activation in humans
    S Klein
    Central Institute of Mental Health, Mannheim, Germany
    Pharmacopsychiatry 36:S191-4. 2003
    ..In men fMRI activation was independent of stimulus valence. These results suggest to take gender differences into account when emotional paradigms are tested in functional brain imaging...
  3. doi request reprint Neurotransmitter systems in alcohol dependence
    A Heinz
    Department of Psychiatry and Psychotherapy, CCM, Charite University Medicine, Berlin, Germany
    Pharmacopsychiatry 42:S95-S101. 2009
    ..g. between brain atrophy and genes associated with glutamatergic and dopaminergic neurotransmission...
  4. doi request reprint Construction and interpretation of self-related function and dysfunction in Intercultural Psychiatry
    A Heinz
    Department of Psychiatry and Psychotherapy, Charite Berlin, Germany
    Eur Psychiatry 27:S32-43. 2012
    ..Conscious self-reflection and its narrative articulation, on the other hand, is necessarily imbued with social and cultural norms, images and events, often of conflicting nature...
  5. ncbi request reprint Serotonin transporter availability correlates with alcohol intake in non-human primates
    A Heinz
    Clinical Brain Disorders Branch, NIMH NIH, Bethesda, MD, USA
    Mol Psychiatry 8:231-4. 2003
    ..81, P=0.006). These observations indicate that there may be a direct relationship between serotonin transporter availability and alcohol intake after controlling for aggression and alcohol response on first exposure...
  6. ncbi request reprint [Thujon and absinthe--a historical misperception?]
    A Heinz
    Universitatsklinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Fortschr Neurol Psychiatr 75:309-10. 2007
  7. ncbi request reprint Genetic research with intermediate phenotypes: phenocopies, perspectives and pitfalls
    Andreas Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medical Center Berlin, Charite Campus Mitte, Berlin, Germany
    Addiction 102:1696-7. 2007
  8. ncbi request reprint Neurobiological correlates of the disposition and maintenance of alcoholism
    A Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S255-8. 2003
    ..New treatment options include pharmacological approaches and indicate that behavior or motivational therapy and the attendance of patient groups may equally reduce the relapse risk...
  9. ncbi request reprint [Genetic and pharmacological effects on prefrontal cortical function in schizophrenia]
    Andreas Heinz
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin
    Nervenarzt 75:845-56. 2004
    ..Molecular brain imaging combines imaging techniques with the assessment of genotype effects and represents a powerful tool for the understanding of neuropsychiatric disorders...
  10. ncbi request reprint The effects of catechol O-methyltransferase genotype on brain activation elicited by affective stimuli and cognitive tasks
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center, Campus Mitte, Berlin, Germany
    Rev Neurosci 17:359-67. 2006
    ..Thus the met158 allele seems to be beneficial during the performance of working memory and attention-related tasks, whereas the val158 allele appears to be advantageous during the processing of aversive emotional stimuli...
  11. ncbi request reprint Pharmacogenetic insights to monoaminergic dysfunction in alcohol dependence
    Andreas Heinz
    Department of Psychiatry, Campus Charite Mitte, Charite University Medicine Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 174:561-70. 2004
    ..The severity and time-course of recovery of these neuroadaptive changes may depend on the genetic constitution of monoamine transporters and receptors and contribute to the relapse risk of alcoholics...
  12. ncbi request reprint Molecular brain imaging and the neurobiology and genetics of schizophrenia
    A Heinz
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S152-7. 2003
    ..Molecular brain imaging can help to unravel the complex interactions between genes and environment and its association with neuronal network dysfunction in schizophrenia...
  13. ncbi request reprint Effects of acute psychological stress on adhesion molecules, interleukins and sex hormones: implications for coronary heart disease
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 165:111-7. 2003
    ..Cell adhesion molecules may be activated by psychological stress exposure, depending on their interaction with the interleukin network, sex hormones and cortisol secretion...
  14. ncbi request reprint Brain activation elicited by affectively positive stimuli is associated with a lower risk of relapse in detoxified alcoholic subjects
    Andreas Heinz
    Department of Psychiatry, Charite University Medical Center Berlin, CCM, Berlin, Germany
    Alcohol Clin Exp Res 31:1138-47. 2007
    ..We assessed whether brain activation elicited by (1) alcohol associated, (2) affectively positive, and (3) negative versus neutral stimuli is associated with the subsequent risk of relapse...
  15. ncbi request reprint Relationship between cortisol and serotonin metabolites and transporters in alcoholism [correction of alcolholism]
    A Heinz
    Intramural Research Program, Clinical Brain Disorders Branch NIMH, Bethesda, MD, USA
    Pharmacopsychiatry 35:127-34. 2002
    ..We assessed the interaction between stress hormone activation, serotonin transporters, monoamine metabolites in the cerebrospinal fluid (CSF), and mood states in male and female alcoholics and healthy control subjects...
  16. pmc Dopaminergic dysfunction in schizophrenia: salience attribution revisited
    Andreas Heinz
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Charite Campus Mitte, 10117 Berlin, Germany
    Schizophr Bull 36:472-85. 2010
    ....
  17. ncbi request reprint Reduced central serotonin transporters in alcoholism
    A Heinz
    Clinical Brain Disorders Branch, NIMH, Washington, D C, USA
    Am J Psychiatry 155:1544-9. 1998
    ..The authors explored whether serotonergic dysfunction is associated with anxiety and depression, which increase the risk of relapse in alcoholics...
  18. doi request reprint Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patients
    I Puls
    Department of Psychiatry and Psychotherapy, CCM, Charite University Medicine, Berlin, Germany
    Biol Psychol 79:126-36. 2008
    ..These data are in line with prior studies supporting a role for dopamine-glutamate interaction in modulation of alcohol disease...
  19. doi request reprint Dopamine-modulated aversive emotion processing fails in alcohol-dependent patients
    T Kienast
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Pharmacopsychiatry 46:130-6. 2013
    ....
  20. ncbi request reprint Gene-gene effects on central processing of aversive stimuli
    M N Smolka
    Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
    Mol Psychiatry 12:307-17. 2007
    ..Effects of 5-HTT and COMT genotypes did not affect brain processing of pleasant stimuli. These data indicate that functional brain imaging may be used to assess the interaction of multiple genes on the function of neuronal networks...
  21. ncbi request reprint Severity of depression in abstinent alcoholics is associated with monoamine metabolites and dehydroepiandrosterone-sulfate concentrations
    A Heinz
    National Institute on Alcohol Abuse and Alcoholism, Bethesda, MD 20892, USA
    Psychiatry Res 89:97-106. 1999
    ....
  22. ncbi request reprint Development of alcohol-associated cues and cue-induced brain activation in alcoholics
    J Wrase
    Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117, Berlin, Germany
    Eur Psychiatry 17:287-91. 2002
    ..These observations suggest that standardized pictures of alcoholic beverages can be used to assess brain circuits involved in the processing and evaluation of alcohol cues...
  23. ncbi request reprint Serotonergic dysfunction, negative mood states, and response to alcohol
    A Heinz
    Central Institute of Mental Health, University of Heidelberg, Germany
    Alcohol Clin Exp Res 25:487-95. 2001
    ..Serotonergic dysfunction may be associated with three behavior patterns relevant for alcoholism: impulsive aggression, negative mood states, and a low response to alcohol intake...
  24. ncbi request reprint [Cue-induced alcohol craving. Neurobiological correlates and clinical relevance]
    J Wrase
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Germany
    Nervenarzt 77:1051-2, 1055-8, 1060-3. 2006
    ..These findings point to specific indications for psychotherapeutic and additive pharmacological treatment options...
  25. ncbi request reprint Alcohol-associated stimuli activate the ventral striatum in abstinent alcoholics
    D F Braus
    Central Institute of Mental Health, Mannheim, Federal Republic of Germany
    J Neural Transm 108:887-94. 2001
    ..This observation supports the hypothesis that alcohol use affects areas involved in brain reward circuits and that their stimulus-induced activation may be associated with an increased risk for relapse...
  26. ncbi request reprint Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine
    Florian Schlagenhauf
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychopharmacology (Berl) 196:673-84. 2008
    ..This may not be the case with newer neuroleptics such as olanzapine, which show less dopamine D2 receptor blockade and a faster off-rate from the receptor...
  27. ncbi request reprint Correlation between dopamine D(2) receptors in the ventral striatum and central processing of alcohol cues and craving
    Andreas Heinz
    Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    Am J Psychiatry 161:1783-9. 2004
    ..Prolonged D(2) receptor dysfunction in the ventral striatum may interfere with a dopamine-dependent error detection signal and bias the brain reward system toward excessive attribution of incentive salience to alcohol-associated stimuli...
  28. ncbi request reprint Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charité Mitte CCM, Schumannstr 20 21, Berlin 10117, Germany
    Psychopharmacology (Berl) 187:222-8. 2006
    ..Dysfunction of the dopaminergic reward system may contribute to negative symptoms in schizophrenia...
  29. doi request reprint Efficacy and safety of levetiracetam for outpatient alcohol detoxification
    C A Muller
    Department of Psychiatry, Charite Campus Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Pharmacopsychiatry 43:184-9. 2010
    ..The aim of this study was to examine the efficacy, medical safety and mid-term outcome of levetiracetam, a drug with no marked liver toxicity, for outpatient alcohol detoxification...
  30. doi request reprint Mental health of Turkish women in Germany: resilience and risk factors
    Z Bromand
    Department of Psychiatry and Psychotherapy at St Hedwig Hospital, Charite University Medicine Berlin, Germany
    Eur Psychiatry 27:S17-21. 2012
    ..The purpose of the present study was to examine the protective and risk factors of mental distress among Turkish women living in Germany...
  31. doi request reprint A preliminary study of increased amygdala activation to positive affective stimuli in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Bipolar Disord 11:70-5. 2009
    ..The present study in hypomanic and manic patients explored how amygdala responses to affective stimuli depend on the valence of the stimuli presented...
  32. ncbi request reprint The startle reflex in alcohol-dependent patients: changes after cognitive-behavioral therapy and predictive validity for drinking behavior. A pilot study
    Sabine Loeber
    Department of Addictive Behavior and Addiction Medicine, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
    Psychother Psychosom 76:385-90. 2007
    ..Further, we examined whether the affect-modulated startle reflex is a predictor of treatment success...
  33. ncbi request reprint Different neural systems adjust motor behavior in response to reward and punishment
    Jana Wrase
    Department of Psychiatry, Charité Universitätsmedizin Berlin Charité Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Neuroimage 36:1253-62. 2007
    ..Our results provide evidence that different but somewhat overlapping circuits mediate the same behavioral adaptation when it is driven by different incentive outcomes...
  34. doi request reprint [Compulsory treatment under legal uncertainty: part 2: consequences of legal uncertainty in clinical practice - suggestions for improvement]
    S Muller
    Klinik fur Psychiatrie und Psychotherapie, Forschungsbereich Mind and Brain, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Deutschland
    Nervenarzt 83:1150-5. 2012
    ..It is decisive that the characteristics of mental diseases and the possibilities of modern treatment are taken into consideration in order to suitably respect patient autonomy without neglecting the necessary help...
  35. ncbi request reprint Anhedonia, self-experience in schizophrenia, and implications for treatment
    G Juckel
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S176-80. 2003
    ..Understanding the neurobiological correlates of motivation and pleasure may provide new options to treat anhedonia in patients with schizophrenia...
  36. doi request reprint Switching schizophrenia patients from typical neuroleptics to olanzapine: effects on BOLD response during attention and working memory
    Florian Schlagenhauf
    Department of Psychiatry, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Eur Neuropsychopharmacol 18:589-99. 2008
    ..However, medication status had influences on the activation during attentional task (0-back), emphasizing the importance of baseline selection in pharmacological fMRI studies...
  37. ncbi request reprint Correlation of stable elevations in striatal mu-opioid receptor availability in detoxified alcoholic patients with alcohol craving: a positron emission tomography study using carbon 11-labeled carfentanil
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    Arch Gen Psychiatry 62:57-64. 2005
    ..Blockade of mu-opiate receptors with naltrexone reduces the relapse risk among some but not all alcoholic individuals...
  38. ncbi request reprint Cue-induced activation of the striatum and medial prefrontal cortex is associated with subsequent relapse in abstinent alcoholics
    Sabine M Grüsser
    Department of Medical Psychology, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Psychopharmacology (Berl) 175:296-302. 2004
    ..Animal experiments have provided evidence that the striatum and medial prefrontal cortex play a predominant role in the acquisition and maintenance of drug-seeking behavior...
  39. doi request reprint Dopamine in amygdala gates limbic processing of aversive stimuli in humans
    Thorsten Kienast
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Neurosci 11:1381-2. 2008
    ..Our results suggest that individual dopamine storage capacity in amygdala subserves modulation of emotional processing in amygdala and dorsal cingulate, thereby contributing to individual differences in anxious temperament...
  40. ncbi request reprint Severity of nicotine dependence modulates cue-induced brain activity in regions involved in motor preparation and imagery
    Michael N Smolka
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Psychopharmacology (Berl) 184:577-88. 2006
    ..Cue-induced brain activation is associated with self-reported craving but further correlates are widely unknown...
  41. doi request reprint Dorsal striatal-midbrain connectivity in humans predicts how reinforcements are used to guide decisions
    Thorsten Kahnt
    Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin Charité Campus Mitte, Berlin, Germany
    J Cogn Neurosci 21:1332-45. 2009
    ..These results suggest that connections between the putative SN and the DS are critical for modulating action values in the DS according to both positive and negative reinforcements to guide future decision making...
  42. ncbi request reprint Catechol-O-methyltransferase val158met genotype affects processing of emotional stimuli in the amygdala and prefrontal cortex
    Michael N Smolka
    Central Institute of Mental Health, 68159 Mannheim, Germany
    J Neurosci 25:836-42. 2005
    ....
  43. ncbi request reprint Reward craving and withdrawal relief craving: assessment of different motivational pathways to alcohol intake
    Andreas Heinz
    Department of Addictive Behaviour and Addiction Medicine, Humboldt University, Berlin, Germany
    Alcohol Alcohol 38:35-9. 2003
    ....
  44. doi request reprint [Neurobiology of behavioral addictions]
    F Kiefer
    Klinik für Abhängiges Verhalten und Suchtmedizin, Zentralinstitut fur Seelische Gesundheit, Mannheim, Germany
    Nervenarzt 84:557-62. 2013
    ..The main focuses are on changes in neurocognitive processes, such as cue reactivity, reward and punishment processing and behavioral control...
  45. ncbi request reprint Dopamine and the diseased brain
    T Kienast
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Schumannstrasse 20 21, 10117 Berlin, Germany
    CNS Neurol Disord Drug Targets 5:109-31. 2006
    ....
  46. doi request reprint Psychodynamic vulnerability factors in the development of panic disorders--a prospective trial in patients after vestibular neuritis
    F Godemann
    Center for Neurology, Psychiatry and Psychotherapy, St Joseph Hospital, Berlin, Germany
    Psychopathology 42:99-107. 2009
    ..g. in the area of autonomy vs. dependence) or deficient psychological structure could predict later panic disorder, as might be expected based on psychodynamic theory...
  47. ncbi request reprint DASB -in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer
    René Hummerich
    Biochemical Laboratory, Central Institute of Mental Health, Mannheim, Germany
    J Neurochem 90:1218-26. 2004
    ..4 nm). These findings suggest DASB to be a highly selective PET tracer to visualize the density of serotonergic synapses in human brain...
  48. ncbi request reprint Serotonin transporter genotype (5-HTTLPR): effects of neutral and undefined conditions on amygdala activation
    Andreas Heinz
    Department of Psychiatry, Charite University Medicine Berlin, Campus Charite Mitte, Germany
    Biol Psychiatry 61:1011-4. 2007
    ..However, a recent report suggested that this interaction is driven by amygdala deactivation during presentation of neutral stimuli in s carriers...
  49. doi request reprint Reduction of auditory event-related P300 amplitude in subjects with at-risk mental state for schizophrenia
    Seza Ozgurdal
    Department of Psychiatry, Ruhr University Bochum, LWL University Hospital, Germany
    Schizophr Res 105:272-8. 2008
    ..e. before a manifestation of full-blown psychosis, and that these changes seem to have a progressive course from prodromal to chronic state of schizophrenia as assumed in this cross-sectional study...
  50. pmc Hippocampal morphology and distinguishing late-onset from early-onset elderly depression
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin
    Am J Psychiatry 165:229-37. 2008
    ..This study used three-dimensional mapping techniques to identify regional hippocampal abnormalities in early- and late-onset depression. Neuropsychological correlates of hippocampal morphology were also investigated...
  51. pmc Functional impact of a recently identified quantitative trait locus for hippocampal volume with genome-wide support
    S Erk
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Transl Psychiatry 3:e287. 2013
    ....
  52. doi request reprint Cortical thickness of superior frontal cortex predicts impulsiveness and perceptual reasoning in adolescence
    C Schilling
    Department of Psychiatry and Psychotherapy, Charité University Medicine Campus Mitte, Clinic for Psychiatry and Psychotherapy, Berlin, Germany
    Mol Psychiatry 18:624-30. 2013
    ..The results may facilitate the understanding of the role of impulsiveness in several psychiatric disorders associated with prefrontal dysfunctions and cognitive deficits...
  53. pmc How the serotonin transporter 5-HTTLPR polymorphism influences amygdala function: the roles of in vivo serotonin transporter expression and amygdala structure
    A Kobiella
    Department of Psychiatry and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Transl Psychiatry 1:e37. 2011
    ..Our findings stress the role of genetic effects during neurodevelopment...
  54. doi request reprint Explanatory models of addictive behaviour among native German, Russian-German, and Turkish youth
    S Penka
    Department of Psychiatry and Psychotherapy, Charite University Medical Center, Campus Mitte, Berlin, Germany
    Eur Psychiatry 23:36-42. 2008
    ..Terms that are central to Western medical models of disease may otherwise be misunderstood, misinterpreted, or simply rejected...
  55. ncbi request reprint [Alcohol-related disorders: etiopathology and therapeutic considerations]
    J Hein
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin, Berlin, Germany
    Fortschr Neurol Psychiatr 75:10-7. 2007
    ..The understanding of these neurobiological principles of alcohol-related disorders should contribute to enhance and improve their therapeutic options...
  56. doi request reprint [Genetics of weight gain associated with antipsychotic medications]
    D J Muller
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin
    Nervenarzt 80:556-63. 2009
    ..Nonetheless the first steps towards genetic risk assessment have been performed, and its application in the near future has become likely...
  57. ncbi request reprint Combination of multimodal imaging and molecular genetic information to investigate complex psychiatric disorders
    J Gallinat
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Pharmacopsychiatry 39:S76-9. 2006
    ..To overcome the limitations of standard statistical methods, new approaches in machine learning have to be adapted to handle multiple parameters obtained from brain imaging and genetic measurements...
  58. ncbi request reprint Reduced fMRI activation of an occipital area in recently detoxified alcohol-dependent patients in a visual and acoustic stimulation paradigm
    Derik Hermann
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Addict Biol 12:117-21. 2007
    ..Attention deficits or a persisting neuronal alteration in the first weeks of alcohol abstinence may have contributed to this result...
  59. doi request reprint Neurocognitive performances in participants of at-risk mental state for schizophrenia and in first-episode patients
    Seza Ozgurdal
    Early Recognition and Therapy Centre for Beginning Psychoses Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Bochum, Germany
    J Clin Exp Neuropsychol 31:392-401. 2009
    ..Results suggest that high-risk participants do perform at average neurocognitive performance levels at all tested domains compared with normative data. Compared to norm values first-episode patients showed decreased attention abilities...
  60. doi request reprint Ventral striatal activation during reward anticipation correlates with impulsivity in alcoholics
    Anne Beck
    Department of Psychiatry, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Biol Psychiatry 66:734-42. 2009
    ..We explored whether functional brain activation during anticipation of incentive stimuli is associated with impulsiveness in detoxified alcoholics and healthy control subjects...
  61. pmc Prefrontal cortex fails to learn from reward prediction errors in alcohol dependence
    Soyoung Q Park
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Neurosci 30:7749-53. 2010
    ..Furthermore, they extend the scope of neurobiological deficits underlying addiction beyond the focus on the striatum...
  62. doi request reprint [How Can we provide better services for demented nursing home residents suffering from apathy?]
    Yvonne Treusch
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Berlin
    Psychiatr Prax 37:84-8. 2010
    ..The development of a brief intervention for nursing home residents combining physical activation and reminiscence therapy in order to reactivating apathic residents and increasing their quality of life will be described...
  63. pmc Hippocampal subdivision and amygdalar volumes in patients in an at-risk mental state for schizophrenia
    Henning Witthaus
    Early Recognition and Therapy Centre for Beginning Psychoses Bochum, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, Bochum, Germany
    J Psychiatry Neurosci 35:33-40. 2010
    ..Furthermore, no subregions of the hippocampus have been investigated in people at UHR...
  64. ncbi request reprint Low level of response to alcohol as associated with serotonin transporter genotype and high alcohol intake in adolescents
    Anne S Hinckers
    Department of Psychosomatics, Central Institute of Mental Health, Mannheim, Germany
    Biol Psychiatry 60:282-7. 2006
    ..To date, all studies of relevant polymorphisms have been carried out in populations in the United States...
  65. doi request reprint Searching for responders to acamprosate and naltrexone in alcoholism treatment: rationale and design of the PREDICT study
    Karl Mann
    Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany
    Alcohol Clin Exp Res 33:674-83. 2009
    ..The "reward drinker/craver" is mainly associated with alterations in the dopaminergic and opioidergic system and responds to naltrexone...
  66. ncbi request reprint Correlation of alcohol craving with striatal dopamine synthesis capacity and D2/3 receptor availability: a combined [18F]DOPA and [18F]DMFP PET study in detoxified alcoholic patients
    Andreas Heinz
    Central Institute of Mental Health, Mannheim, Germany
    Am J Psychiatry 162:1515-20. 2005
    ..In this study, positron emission tomography (PET) was used to compare dopamine synthesis capacity in the striatum in alcoholic patients and healthy comparison subjects...
  67. pmc Genetic risk for nicotine dependence in the cholinergic system and activation of the brain reward system in healthy adolescents
    F Nees
    Department of Cognitive and Clinical Neuroscience, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
    Neuropsychopharmacology 38:2081-9. 2013
    ..Thus, it seems to have a major role in the processing of and behavioral adaptation to changing reward outcomes. ..
  68. doi request reprint Socio-economic status and emotional distress of female Turkish immigrants and native German women living in Berlin
    M C Aichberger
    Department of Psychiatry and Psychotherapy at St Hedwig Hospital, Charite University Medicine Berlin, Große Hamburger Straße 5 11, 10115 Berlin, Germany
    Eur Psychiatry 27:S10-6. 2012
    ..The purpose of this study was to examine the association of socioeconomic status (SES) and emotional distress in women of Turkish descent and in women of German descent...
  69. doi request reprint The dopamine system in mediating alcohol effects in humans
    K Charlet
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, Germany
    Curr Top Behav Neurosci 13:461-88. 2013
    ..Finally, we will discuss how the neurobiological and neurochemical mechanisms of alcohol-associated alterations in reward processing and learning can interact with personality traits, cognition and emotion processing...
  70. doi request reprint Involvement of the atrial natriuretic peptide transcription factor GATA4 in alcohol dependence, relapse risk and treatment response to acamprosate
    F Kiefer
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Pharmacogenomics J 11:368-74. 2011
    ..These results could help to identify those alcohol-dependent patients who may be at an increased risk of relapse and who may better respond to treatment with acamprosate...
  71. doi request reprint [The importance of depressive syndromes for incipient Alzheimer-type dementia in advanced age]
    M A Rapp
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Berlin, Deutschland
    Nervenarzt 82:1140-4. 2011
    ..The findings summarized in this review underline the central importance of depressive disorders for the diagnosis and treatment of psychiatric disorders in later life...
  72. doi request reprint Genes and neuroimaging: advances in psychiatric research
    J Gallinat
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neurodegener Dis 5:277-85. 2008
    ..Furthermore, recently identified putative susceptibility genes for schizophrenia (neuregulin 1, dysbindin, G72) are briefly discussed...
  73. doi request reprint [Neurobiology of substance-related addiction: findings of neuroimaging]
    T Kienast
    Klinik für Psychiatrie und Psychotherapie der Charité, CCM, Universitatsmedizin Berlin, Germany
    Fortschr Neurol Psychiatr 76:S68-76. 2008
    ..Besides discussing brain imaging studies on the neurobiological correlates of drug dependence, this review also presents studies on vulnerability factors that predispose individuals to excessive drug intake...
  74. doi request reprint Depression in middle-aged and older first generation migrants in Europe: results from the Survey of Health, Ageing and Retirement in Europe (SHARE)
    M C Aichberger
    Psychiatric Outpatient Clinic, Department of Psychiatry and Psychotherapy, St Hedwig Hospital, Charite, University Medicine, Große Hamburger Straße 5 11, Berlin, Germany
    Eur Psychiatry 25:468-75. 2010
    ..To determine the prevalence of depression in migrants aged 50 years or older in comparison to residents without a history of migration in 11 European countries...
  75. doi request reprint A new paradigm (Westphal-Paradigm) to study the neural correlates of panic disorder with agoraphobia
    A Wittmann
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 261:185-94. 2011
    ....
  76. doi request reprint [Multimodal imaging with PET, fMRI and genetic research]
    J Wrase
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Berlin
    Fortschr Neurol Psychiatr 76:278-85. 2008
    ..The clinical relevance of these studies will be illustrated and discussed...
  77. ncbi request reprint Extrapyramidal side effects with risperidone and haloperidol at comparable D2 receptor occupancy levels
    M B Knable
    National Institute of Mental Health, Intramural Research Program, Clinical Brain Disorders Branch, Washington, D C 20032, USA
    Psychiatry Res 75:91-101. 1997
    ..Based on these observations, it is concluded that 5-HT2 blockade obtained with risperidone at D2 occupancy rates of 60% and above does not appear to protect against the risk for extrapyramidal side effects...
  78. ncbi request reprint Hippocampal glutamate concentration predicts cerebral theta oscillations during cognitive processing
    J Gallinat
    Clinic for Psychiatry and Psychotherapy PUK im SHK, Charite University Medicine Berlin, Campus Mitte, St Hedwig Krankenhaus, Turmstrasse 21, 10559 Berlin, Germany
    Psychopharmacology (Berl) 187:103-11. 2006
    ..Human evidence for such relationships is lacking...
  79. ncbi request reprint Neurotransmitter changes by interferon-alpha and therapeutic implications
    M Schaefer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S203-6. 2003
    ..We review recent research about IFN-associated neurotransmitter changes in the central nervous system and discuss treatment strategies...
  80. ncbi request reprint Serotonergic dysfunction in addiction: effects of alcohol, cigarette smoking and heroin on platelet 5-HT content
    L G Schmidt
    Department of Psychiatry, Universitatsklinikum Benjamin Franklin, Free University of Berlin, Germany
    Psychiatry Res 72:177-85. 1997
    ....
  81. ncbi request reprint Genotype effects on neurodegeneration and neuroadaptation in monoaminergic neurotransmitter systems
    A Heinz
    Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Mannheim, Germany
    Neurochem Int 37:425-32. 2000
    ....
  82. ncbi request reprint Stimulus-induced craving and startle potentiation in abstinent alcoholics and controls
    S M Grusser
    Department of Psychology, Clinical Psychology and Behavioral Neuroscience Unit, Humboldt University, Hausvogteiplatz 5 7, 10117 Berlin, Germany
    Eur Psychiatry 17:188-93. 2002
    ..These findings indicate that alcohol-related stimuli may have appetitive incentive salience for alcoholics in spite of verbal reports of craving and valence to the opposite...
  83. ncbi request reprint Cue exposure in the treatment of alcohol dependence: effects on drinking outcome, craving and self-efficacy
    Sabine Loeber
    Department of Addictive Behaviour and Addiction Medicine at the University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
    Br J Clin Psychol 45:515-29. 2006
    ..We hypothesized that cue exposure treatment is associated with a stronger decline of craving, a stronger increase in self-efficacy and has beneficial effects on drinking behaviour after discharge...
  84. pmc The pharmacotherapy of neuropsychiatric symptoms of dementia: a cross-sectional study in 18 homes for the elderly in Berlin
    Tomislav Majic
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte, Berlin, Germany
    Dtsch Arztebl Int 107:320-7. 2010
    ..International guidelines recommend syndrome-specific pharmacotherapy. We studied the question whether drug-prescribing practices are, in fact, syndrome-specific...
  85. doi request reprint Lesion of the medial prefrontal cortex and the subthalamic nucleus selectively affect depression-like behavior in rats
    Julia Klein
    Department of Psychiatry and Psychotherapy, Charite Campus Mitte, University Medicine Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Behav Brain Res 213:73-81. 2010
    ....
  86. doi request reprint Prediction of psychosis in adolescents and young adults at high risk: results from the prospective European prediction of psychosis study
    Stephan Ruhrmann
    Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener Strasse 62, 50924 Cologne, Germany
    Arch Gen Psychiatry 67:241-51. 2010
    ..Existing criteria need improvement in terms of specificity and individual risk assessment to allow for better targeted and earlier interventions...
  87. ncbi request reprint Dysfunction of ventral striatal reward prediction in schizophrenia
    Georg Juckel
    Department of Psychiatry, Charite University Medical Center, Campus Charite Mitte, CCM, Schumannstr 20 21, 10117 Berlin, Germany
    Neuroimage 29:409-16. 2006
    ..We used functional magnetic resonance imaging (fMRI) to assess the BOLD response in the ventral striatum of unmedicated schizophrenics during presentation of reward-indicating and loss-indicating stimuli...
  88. doi request reprint Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons
    Kathrin Scheuch
    Neuropsychiatry and Laboratory of Molecular Psychiatry, Charite Universitatsmedizin Berlin, 10117 Berlin, Germany
    Brain Res 1307:14-21. 2010
    ..Our results suggest that lithium can modify tph2 gene expression and 5-HT release in raphe neurons, providing new insight into the serotonergic mechanisms of action of lithium...
  89. doi request reprint White matter abnormalities in subjects at ultra high-risk for schizophrenia and first-episode schizophrenic patients
    Henning Witthaus
    Early Recognition and Therapy Centre for beginning psychosis Bochum BoFit, Department of Psychiatry, Psychotherapy and Psychosomatic Medicine, Ruhr University of Bochum, 44791 Bochum, Germany
    Schizophr Res 102:141-9. 2008
    ..Furthermore, white matter abnormalities seem to progress after transition into schizophrenia...
  90. ncbi request reprint Glucose utilization in the medial prefrontal cortex correlates with serotonin turnover rate and clinical depression in alcoholics
    Wendol Williams
    National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    Psychiatry Res 132:219-24. 2004
    ..This pilot study indicates that a dysfunction of medial PFC may interact with central serotonin turnover and negative mood states during early abstinence...
  91. ncbi request reprint Huntington's disease: phenomenological diversity of a neuropsychiatric condition that challenges traditional concepts in neurology and psychiatry
    Heike Tost
    Central Institute of Mental Health, University of Heidelberg, Germany
    Am J Psychiatry 161:28-34. 2004
  92. pmc Mapping callosal morphology in early- and late-onset elderly depression: an index of distinct changes in cortical connectivity
    Martina Ballmaier
    Department of Psychiatry and Psychotherapy, Charite University Medicine, Campus Mitte, Berlin, Germany
    Neuropsychopharmacology 33:1528-36. 2008
    ..Patients with a late onset of depression may be at higher risk of illness progression and eventually dementia conversion than early-onset depression, with potentially important implications for research and therapy...
  93. doi request reprint The influence of stigma on depression, overall psychological distress, and somatization among female Turkish migrants
    A Heredia Montesinos
    Department of Psychiatry and Psychotherapy at St Hedwig Hospital, Charite University Medicine Berlin, Germany Grosse Hamburger Straße 5 11, 10115 Berlin, Germany amanda heredia
    Eur Psychiatry 27:S22-6. 2012
    ..Also, stigma associated with mental disorders can affect patients'symptom presentation...
  94. doi request reprint [Neuroimaging diagnosis of alcohol dependence]
    M Kensche
    Klinik fur Psychiatrie und Psychotherapie, Campus Charite Mitte, Charite, Universitatsmedizin Berlin, Chariteplatz 1, 10117, Berlin, Deutschland
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 53:326-31. 2010
    ..Harmful consequences of alcohol intake also include neurotoxic effects on the central nervous system characterized by local and global atrophy. These findings can be best diagnosed with neuroimaging...
  95. doi request reprint [Evidence-based psychotherapy: addiction and personality disorders as comorbidities]
    T Kienast
    Klinik fur Psychiatrie und Psychotherapie, St Hedwig Krankenhaus, Charite Universitatsmedizin Berlin, Campus Mitte, Grosse Hamburger Str 5 11, 10115, Berlin, Deutschland
    Nervenarzt 80:1050-9. 2009
    ..This article summarizes the current state of knowledge and introduces both methods by highlighting the core therapeutic strategies...
  96. ncbi request reprint Self-reported empathic abilities in schizophrenia
    C Montag
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Schizophr Res 92:85-9. 2007
    ..e. cognitive aspects of mental state attribution, the ability to infer emotional experiences of others, i.e. affective empathy, has not been investigated so far...
  97. ncbi request reprint Mental health care in Berlin
    M Schouler-Ocak
    Department of Psychiatry, Charité University Medical Centre, Hedwig s Hospital, Berlin, Germany
    Eur Psychiatry 20:S270-3. 2005
    ..To provide information on the mental health care system in Berlin, Germany...
  98. doi request reprint [New procedures for recognition and differentiation of depression in immigrants. Case report of a patient with Turkish immigrant background]
    M Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus, Berlin, Deutschland
    Nervenarzt 81:873-7. 2010
    ..The transcultural aspects of depression are illustrated with a case report...
  99. doi request reprint [Patients of immigrant origin in inpatient psychiatric facilities. Differences between first and second generation: nationwide questionnaire of the Psychiatry and Migration Working Group of the German Federal Conference of Psychiatric Hospital Directors]
    M Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus Berlin, Grosse Hamburger Strasse 5 11, 10115 Berlin
    Nervenarzt 81:86-94. 2010
    ..Whilst first generation of inpatients with migration history demonstrated higher educational levels, second generation of inpatients with migration history showed fewer linguistic difficulties...
  100. ncbi request reprint [Aggressive and impulsive behavior: neurobiological models explain how affectregulation might work and social skills develop]
    T Kienast
    Klinik für Psychiatrie und Psychotherapie der Charité, CCM, Universitatsmedizin Berlin
    MMW Fortschr Med 149:29-32. 2007
    ..The serotonin turnover of an individual is controlled by environmental influences in interaction with genetic factors. In this article, impulse control disorders will be discussed with regard to their origin and social effects...
  101. doi request reprint Patients of immigrant origin in inpatient psychiatric facilities. A representative national survey by the Psychiatry and Migration Working Group of the German Federal Conference of Psychiatric Hospital Directors
    M Schouler-Ocak
    Psychiatrische Universitätsklinik der Charité im St Hedwig Krankenhaus Berlin, Germany
    Eur Psychiatry 23:21-7. 2008
    ..Patients of immigrant origin were significantly more likely to receive an ICD-10 F2 diagnosis, and it was precisely patients with this diagnosis who were observed to experience difficulties in communication with caregivers...