Ortrud Vargas Hein

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Hirudin versus heparin for anticoagulation in continuous renal replacement therapy
    O Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    Intensive Care Med 27:673-9. 2001
  2. ncbi request reprint Torsemide versus furosemide after continuous renal replacement therapy due to acute renal failure in cardiac surgery patients
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Berlin, Germany
    Ren Fail 27:385-92. 2005
  3. ncbi request reprint Protracted bleeding after hirudin anticoagulation for cardiac surgery in a patient with HIT II and chronic renal failure
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Charite University Hospital Berlin, Campus Mitte, Berlin, Germany
    Artif Organs 29:507-10. 2005
  4. pmc Mild hypothermia after near drowning in twin toddlers
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Mitte, Humboldt University, Berlin, Germany
    Crit Care 8:R353-7. 2004
  5. ncbi request reprint Intermittent hirudin versus continuous heparin for anticoagulation in continuous renal replacement therapy
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Berlin, Germany
    Ren Fail 26:297-303. 2004
  6. ncbi request reprint Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Ann Thorac Surg 81:880-5. 2006
  7. ncbi request reprint Anticoagulation in continuous renal replacement therapy
    O Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Campus Mitte, Berlin, Germany
    Contrib Nephrol 144:308-16. 2004
  8. ncbi request reprint Three-year survival after four major post-cardiac operative complications
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Crit Care Med 34:2729-37. 2006
  9. ncbi request reprint Intensive care unit stay of more than 14 days after cardiac surgery is associated with non-cardiac organ failure
    O V Hein
    Department of Anaesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany
    J Int Med Res 34:695-703. 2006
  10. ncbi request reprint [Therapy without improved prognosis?]]
    Ortrud Vargas Hein
    Klinik für Anästhesiologie undoperative Intensivmedizin, Campus Virchow Klinikum und Campus Charité Mitte, Charite Universitatsmedizin Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 43:284-5. 2008

Collaborators

Detail Information

Publications32

  1. ncbi request reprint Hirudin versus heparin for anticoagulation in continuous renal replacement therapy
    O Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    Intensive Care Med 27:673-9. 2001
    ..To compare the efficacy and safety of hirudin and heparin for anticoagulation during continuous renal replacement therapy (CRRT) in critically ill patients...
  2. ncbi request reprint Torsemide versus furosemide after continuous renal replacement therapy due to acute renal failure in cardiac surgery patients
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Berlin, Germany
    Ren Fail 27:385-92. 2005
    ..Torsemide might show a better dose-dependent diuretic effect in ARF patients after CRRT treatment. Serum creatinine and blood urea nitrogen elimination were less pronounced in the furosemide group...
  3. ncbi request reprint Protracted bleeding after hirudin anticoagulation for cardiac surgery in a patient with HIT II and chronic renal failure
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Charite University Hospital Berlin, Campus Mitte, Berlin, Germany
    Artif Organs 29:507-10. 2005
    ....
  4. pmc Mild hypothermia after near drowning in twin toddlers
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Mitte, Humboldt University, Berlin, Germany
    Crit Care 8:R353-7. 2004
    ..We report a case of twin toddlers who both suffered near drowning but with different post-trauma treatment and course, and different neurological outcomes...
  5. ncbi request reprint Intermittent hirudin versus continuous heparin for anticoagulation in continuous renal replacement therapy
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Berlin, Germany
    Ren Fail 26:297-303. 2004
    ..Aim of this prospective-controlled pilot study was to compare the efficacy and safety of intermittent hirudin and continuous heparin for anticoagulation during CRRT in critically ill patients...
  6. ncbi request reprint Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survival
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Ann Thorac Surg 81:880-5. 2006
    ....
  7. ncbi request reprint Anticoagulation in continuous renal replacement therapy
    O Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Campus Mitte, Berlin, Germany
    Contrib Nephrol 144:308-16. 2004
  8. ncbi request reprint Three-year survival after four major post-cardiac operative complications
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
    Crit Care Med 34:2729-37. 2006
    ..The second aim of this study was to evaluate the prevalences and risk factors related to the four major morbidities in this patient population...
  9. ncbi request reprint Intensive care unit stay of more than 14 days after cardiac surgery is associated with non-cardiac organ failure
    O V Hein
    Department of Anaesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Germany
    J Int Med Res 34:695-703. 2006
    ..Since an ICU stay is associated with a higher hospital and long-term mortality, measures should be taken throughout the entire hospital stay to identify and reduce the risk of organ failure...
  10. ncbi request reprint [Therapy without improved prognosis?]]
    Ortrud Vargas Hein
    Klinik für Anästhesiologie undoperative Intensivmedizin, Campus Virchow Klinikum und Campus Charité Mitte, Charite Universitatsmedizin Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 43:284-5. 2008
  11. doi request reprint [Acute renal failure - anticoagulation in continuous renal replacement therapy]
    Ortrud Vargas Hein
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Campus Virchow Klinikum und Campus Charité Mitte, Charite Universitatsmedizin Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 43:294-301; quiz 302. 2008
    ....
  12. pmc Time course of endothelial damage in septic shock: prediction of outcome
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care, University Hospital Charite, Campus Mitte, Berlin, Germany
    Crit Care 9:R323-30. 2005
    ..We investigated the predictive value of the mediators IL-6, IL-8, sELAM-1 and sICAM-1 and their time course in intensive care unit patients who developed septic shock with respect to outcome...
  13. ncbi request reprint Iloprost for additional anticoagulation in continuous renal replacement therapy--a pilot study
    Jurgen Birnbaum
    Department of Anesthesiology and Intensive Care Medicine, Campus Charité Mitte and Campus Charité Virchow Klinikum, Charite University Medicine, Berlin, Germany
    Ren Fail 29:271-7. 2007
    ..The aim of this pilot study was to compare the effect of heparin anticoagulation with and without iloprost administration during continuous renal replacement therapy (CRRT) in critically ill patients...
  14. pmc Circulating immune parameters predicting the progression from hospital-acquired pneumonia to septic shock in surgical patients
    Vera von Dossow
    Department of Anesthesiology and Intensive Care, Charite Universitaetsmedizin Berlin, Campus Mitte, Germany
    Crit Care 9:R662-9. 2005
    ..The secondary aim was to investigate the usefulness of these immune parameters in predicting progression from hospital-acquired pneumonia to septic shock...
  15. ncbi request reprint The combinations C1 esterase inhibitor with coagulation factor XIII and N-acetylcysteine with tirilazad mesylate reduce the leukocyte adherence in an experimental endotoxemia in rats
    Jurgen Birnbaum
    Klinik fur Anaesthesiologie und operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Charité Mitte und Campus Virchow Klinikum, Berlin, Germany
    Clin Hemorheol Microcirc 40:167-76. 2008
    ..FCD was not impaired after LPS challenge and there was no influence of both combinations on the FCD. We conclude that both drug combinations can reduce the leukocyte adherence in a sepsis model in rats...
  16. pmc Effects of dopexamine on the intestinal microvascular blood flow and leukocyte activation in a sepsis model in rats
    Jurgen Birnbaum
    Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine, Berlin, Germany
    Crit Care 10:R117. 2006
    ..The administration of dopexamine may constitute a therapeutical option to improve hepatosplanchnic perfusion in sepsis. In order to verify this hypothesis, we administered dopexamine in an experimental sepsis model in rats...
  17. pmc Altered immune parameters in chronic alcoholic patients at the onset of infection and of septic shock
    Vera von Dossow
    Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
    Crit Care 8:R312-21. 2004
    ....
  18. ncbi request reprint Validity and reliability of the DDS for severity of delirium in the ICU
    Hilke Otter
    Department of Anesthesiology, Charité Universitary Medicine Berlin, Campus Mitte, Germany
    Neurocrit Care 2:150-8. 2005
    ..Until now, there has been no gold standard for monitoring delirium in intensive care unit (ICU) patients. In this prospective cohort study, a new score, the Delirium Detection Score (DDS), for severity of delirium in the ICU was evaluated...
  19. pmc Effects of coagulation factor XIII on intestinal functional capillary density, leukocyte adherence and mesenteric plasma extravasation in experimental endotoxemia
    Jurgen Birnbaum
    Klinik fur Anaesthesiologie und operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Charite Mitte, 10117 Berlin, Schumannstr, Germany
    Crit Care 10:R29. 2006
    ....
  20. ncbi request reprint Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy
    Verena Eggers
    Department of Anaesthesiology and Intensive Care Medicine, University Hospital Charite, Campus Mitte, Humboldt University Berlin, Schumannstrasse 20 21, 10117, Berlin, Germany
    Intensive Care Med 30:1544-51. 2004
    ..To investigate antibiotic-mediated release of tumour necrosis factor (TNF)-alpha and norharman in patients with hospital-acquired pneumonia with and without additional septic encephalopathy...
  21. ncbi request reprint Regional citrate anticoagulation in continuous hemodialysis--acid-base and electrolyte balance at an increased dose of dialysis
    Stanislao Morgera
    Department of Nephrology, University Hospital Charité Campus Mitte, Berlin, Germany
    Nephron Clin Pract 101:c211-9. 2005
    ..This study aimed at establishing a citrate anticoagulation protocol designed for a dialysate flow rate of about 2 l/h...
  22. ncbi request reprint Intermittent high-permeability hemofiltration modulates inflammatory response in septic patients with multiorgan failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Berlin, Germany
    Nephron Clin Pract 94:c75-80. 2003
    ..The present study examines whether intermittent high-permeability hemofiltration has an immunomodulatory effect on polymorphonuclear leukocytes and mononuclear cells...
  23. ncbi request reprint High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Schumannstrasse 20 21, D 10098 Berlin, Germany
    Nephrol Dial Transplant 18:2570-6. 2003
    ..The present study examines whether HP-HF has an impact on peripheral blood mononuclear cell (PBMC) proliferation and whether ultrafiltrate can alter PBMC function in isolates from healthy volunteers...
  24. ncbi request reprint Renal replacement therapy with high-cutoff hemofilters: Impact of convection and diffusion on cytokine clearances and protein status
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Am J Kidney Dis 43:444-53. 2004
    ..This study compares diffusive versus convective high-cutoff renal replacement therapy (RRT) in terms of cytokine clearance rates and effects on plasma protein levels...
  25. ncbi request reprint Metabolic complications during regional citrate anticoagulation in continuous venovenous hemodialysis: single-center experience
    Stanislao Morgera
    Department of Nephrology, Charite, Humboldt University of Berlin, Germany
    Nephron Clin Pract 97:c131-6. 2004
    ....
  26. doi request reprint A safe citrate anticoagulation protocol with variable treatment efficacy and excellent control of the acid-base status
    Stanislao Morgera
    Departmentsof Nephrology, University Hospital Charité Campus Mitte, Berlin, Germany
    Crit Care Med 37:2018-24. 2009
    ..In this article, we provide a safe and an easy-to-handle citrate anticoagulation protocol with variable treatment doses and excellent control of the acid-base status...
  27. ncbi request reprint Impact of combined C1 esterase inhibitor/coagulation factor XIII or N-acetylcysteine/tirilazad mesylate administration on leucocyte adherence and cytokine release in experimental endotoxaemia
    J Birnbaum
    Klinik fur Anaesthesiologie und operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Charité Mitte and Campus Virchow Klinikum, Berlin, Germany
    J Int Med Res 36:748-59. 2008
    ..There was no significant effect on mesenteric plasma extravasation. In conclusion, the administration of C1-INH + factor XIII and NAC + TM reduced endothelial leucocyte adherence and IL-1beta plasma levels, but increased IL-6 levels...
  28. ncbi request reprint Recombinant activated factor VII for treatment of refractory hemorrhage after surgery for acute aortic dissection
    H Grubitzsch
    Department of Cardiovascular Surgery, University of Clinic Charité, Campus Charite Mitte, Berlin, Germany
    J Cardiovasc Surg (Torino) 50:531-4. 2009
    ..Although a risk of thromboembolic complications has to be considered, rFVIIa is a reasonable rescue option in life-threatening hemorrhage and enlarges our hemostatic armamentarium in surgery for acute aortic dissection...
  29. ncbi request reprint Aspirin and clopidogrel taken until 2 days prior to coronary artery bypass graft surgery is associated with increased postoperative drainage loss
    C von Heymann
    Department of Anesthesiology and Intensive Care Medicine, Charite University Hospital Berlin, Berlin, Germany
    Thorac Cardiovasc Surg 53:341-5. 2005
    ..We investigated the impact of time between the last intake of aspirin and clopidogrel before CABG surgery and drainage loss, transfusion requirements and rate of reoperation...
  30. pmc N-acetylcysteine decreases lactate signal intensities in liver tissue and improves liver function in septic shock patients, as shown by magnetic resonance spectroscopy: extended case report
    Ortrud Vargas Hein
    Department of Anesthesiology and Intensive Care Medicine Charité, Campus Mitte, Humboldt University Berlin, Germany
    Crit Care 8:R66-71. 2004
    ..Furthermore, the monoethylglycinexylidide (MEGX) test was used to investigate hepatic function...
  31. ncbi request reprint The effect of stimulating versus nonstimulating catheters for continuous interscalene plexus blocks in short-term pain management
    Juergen Birnbaum
    Department of Anesthesiology and Intensive Care Medicine, Campus Virchow Klinikum and Campus Charite Mitte, Charite University Medicine Berlin, 10117 Berlin, Germany
    J Clin Anesth 19:434-9. 2007
    ..To investigate whether placement, and use of stimulating catheters for interscalene brachial plexus blocks improves short-term postoperative analgesia...
  32. pmc Validation of core competencies during residency training in anaesthesiology
    Heiderose Ortwein
    Department of Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    Ger Med Sci 9:Doc23. 2011
    ..In addition to the descriptive acquisition of data, it was intended to assess the results of the survey to ascertain whether there were differences in the evaluation of these objectives by specialists and registrars...