Research Topics
Genomes and Genes | M GlanemannSummaryAffiliation: Humboldt University Country: Germany Publications
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Publications
Steroid administration before partial hepatectomy with temporary inflow occlusion does not influence cyclin D1 and Ki-67 related liver regenerationMatthias Glanemann
Department of General Surgery, Visceral Surgery and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
Langenbecks Arch Surg 389:380-6. 2004..We investigated the effects of methylprednisolone on hepatocyte proliferation after partial hepatectomy with temporary inflow occlusion...
ChroPac-trial: duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for chronic pancreatitis. Trial protocol of a randomised controlled multicentre trialMarkus K Diener
University of Heidelberg, Department of General, Visceral and Transplantation Surgery, Heidelberg, Germany
Trials 11:47. 2010..A multicentre randomised trial to confirm these results is needed...
Perioperative management in distal pancreatectomy: results of a survey in 23 European participating centres of the DISPACT trial and a review of literatureHelge Bruns
Department of General, Visceral and Transplantation Surgery, Ruprecht Karls University Heidelberg, Heidelberg, Germany
Trials 10:58. 2009..This study's objective was therefore to identify and analyse the current basis of evidence for perioperative management in distal pancreatectomy...
Incidence and indications for reintubation during postoperative care following orthotopic liver transplantationM Glanemann
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, Humboldt University Berlin, Germany
J Clin Anesth 13:377-82. 2001..To analyze the incidence and indications for reintubation during postoperative care following orthotopic liver transplantation (OLT)...
Cobalt-protoporphyrin induced heme oxygenase overexpression and its impact on liver regenerationM Glanemann
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Transplant Proc 37:3223-5. 2005..Thus, it is conceivable that prevention of ischemia-reperfusion injury by HO-1 overexpression also might be beneficial for reduced-size liver grafts without affecting their proliferative capacity...
Hyperperfusion syndrome in small-for-size liversM Glanemann
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Eur Surg Res 37:335-41. 2005..Using an experimental model, we investigated splenectomy as a measure to reduce portal blood flow and its impact on postoperative recovery following extended liver resection...
Fast tracking in liver transplantation: which patient benefits from this approach?M Glanemann
Department of General, Visceral, and Transplantation Surgery, Universitatsmedizin, Berlin, Germany
Transplant Proc 39:535-6. 2007..9%) and specificity (49.5%), area under the ROC curve = 0.703 (standard error = 0.023; 95% confidence interval = 0.671-0.734)...
[Pylorus-preserving pancreatic head resection: a new standard for tumors]M Glanemann
Klinik fUr Allgemein, Visceral und Transplantationschirurgie, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Deutschland
Chirurg 79:1107-14. 2008..Patients can benefit fundamentally from this procedure if it is carried out at a specialized center...
Transplantation of monocyte-derived hepatocyte-like cells (NeoHeps) improves survival in a model of acute liver failureMatthias Glanemann
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Germany
Ann Surg 249:149-54. 2009..Investigation of the efficacy of implantation of monocyte-derived hepatocyte-like cells (NeoHeps) in acute liver failure...
[Orthotopic liver transplantation in case of TIPS stent dislocation]M Glanemann
Klinik fUr Allgemein, Visceral und Transplantationschirurgie, Charite, Campus Virchow Klinikum, Humboldt Universitat zu Berlin, Germany
Zentralbl Chir 127:997-1000. 2002..We conclude that TIPS stent insertion, especially in liver transplant candidates, should only be performed by radiologists in centers with expertise and experience...
Results of end-to-end cavocavostomy during adult liver transplantationMatthias Glanemann
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Humboldt University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
World J Surg 26:342-7. 2002..For only a few exceptions, such as pediatric transplantation, reduced size livers, or size mismatch between donor and recipient, should alternative techniques such as end-to-side or side-to-side cavocavostomy be performed...
Surgical strategies for treatment of malignant pancreatic tumors: extended, standard or local surgery?Matthias Glanemann
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Germany
World J Surg Oncol 6:123. 2008..Due to the development of modern instruments, laparoscopic operations became more and more successful, even in malignant pancreatic diseases. This review summarizes the recent literature on the above mentioned topics...
Subcutaneous administration of epidermal growth factor: a true treatment option in case of postoperative liver failure?Matthias Glanemann
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Int J Surg 7:200-5. 2009..Subcutaneous EGF injection can augment postoperative liver regeneration, however, it might be used only as a prophylactic and not as a therapeutic drug in case of liver insufficiency...
Portal vein angioplasty using a transjugular, intrahepatic approach for treatment of extrahepatic portal vein stenosis after liver transplantationM Glanemann
Department of Surgery, Charite, Humboldt University Berlin, Germany
Transpl Int 14:48-51. 2001....
Postoperative tracheal extubation after orthotopic liver transplantationM Glanemann
Department of General, Visceral and Transplantation Surgery, Charite, Humboldt University Berlin, Germany
Acta Anaesthesiol Scand 45:333-9. 2001..The duration of postoperative mechanical ventilation and its influence on pulmonary function in liver transplant recipients is still debated controversially...
Administration of prostacyclin after liver transplantation: a placebo controlled randomized trialU P Neumann
Klinik für Vizeral und Transplantationschirurgie, Humboldt Universitat zu Berlin, Germany
Clin Transplant 14:70-4. 2000..638 +/- 156 U/L, p < 0.1). These results suggest that administration of PGI2 after OLT improves hepatic-splanchnic oxygenation and may thereby reduce reperfusion injury after OLT...
Changes in serum levels of growth factors in healthy individuals after living related liver donationE A Efimova
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Clinic, University Medicine, Berlin, Germany
Transplant Proc 37:1074-5. 2005....
Effects of human hepatocyte growth factor on the proliferation of human hepatocytes and hepatocellular carcinoma cell linesEkaterina A Efimova
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Eur Surg Res 36:300-7. 2004..The aim of this study was to clarify the role of HGF in the regeneration of human hepatocyte and the growth of residual hepatocellular carcinoma cells after liver resection...
Significance of a T-lymphocytotoxic crossmatch in liver and combined liver-kidney transplantationU P Neumann
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Charite, Virchow Klinikum, Humboldt Universitat zu Berlin, Germany
Transplantation 71:1163-8. 2001..The aim of this study was to evaluate the effect of a positive crossmatch on outcome after OLT and combined liver and kidney transplantation (CLKTx)...
[Second-look operation in pancreatic carcinoma previously assessed as unresectable]P Warnick
Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Augustenburger Platz 1, 13353 Berlin, Deutschland
Zentralbl Chir 135:70-4. 2010..Preoperative diagnostic investigations may help, however, the definite decision on tumour resectability can only be made intraoperatively during explorative laparotomy...
[Metastatic lesions to the pancreas. When is resection reasonable?]M Bahra
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin
Chirurg 79:241-8. 2008..The significance of pancreatic resection for pancreatic metastatic lesions has not yet been sufficiently investigated. A retrospective analysis of patients undergoing pancreatic resections for pancreatic metastases was conducted...
Venous complications after orthotopic liver transplantationU Settmacher
Department of Surgery, Charite, Virchow Klinikum, Humboldt University Berlin, Germany
Clin Transplant 14:235-41. 2000..Usually, treatment of patients with portal vein complications only became necessary when additional complications such as arterial occlusion or bile duct injuries occurred...
Intrasplenic or subperitoneal hepatocyte transplantation to increase survival after surgically induced hepatic failure?G Gabelein
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Eur Surg Res 41:253-9. 2008..As a basis for future clinical questions, we evaluated the efficacy of hepatocyte transplantation in a surgical model using a subperitoneal or intrasplenic approach for cell implantation...
Adult liver transplantation using liver grafts from donors over 70 years of ageD H Borchert
Department of General, Visceral, and Transplant Surgery, Berlin, Germany
Transplant Proc 37:1186-7. 2005..Liver function tests, cholestasis, and retention parameters were normal after 1 year follow up. Thus, we recommend to accept liver grafts from donors older than 70 years to expand the organ pool...
Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: technical aspectsA Spinelli
Department of General, Visceral and Transplantation Surgery, , Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
Eur J Surg Oncol 34:831-5. 2008
Hepatic artery calcification in a liver transplant recipientR M Eisele
Department of General, Visceral and Transplant Surgery, Charite Campus Virchow Clinic, University of Berlin, Berlin, Germany
Transplant Proc 41:777-9. 2009..It thus seems unlikely that hepatic artery calcification as a single finding is to be considered a serious pathologic entity, even for a liver graft...
[Distal pancreatectomy with splenectomy and en bloc resection of the celiac trunk for locally advanced cancer of the pancreatic body with infiltration of the celiac trunk]Andreas Andreou
Klinik fUr Allgemein, Visceral und Transplantationschirurgie, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany
Med Klin (Munich) 105:227-31. 2010..Distal pancreatectomy with resection of the celiac trunk was described as a new concept for the curative treatment of these tumors...
Inhibitory effect of curcumin on early liver regeneration following partial hepatectomy in ratsDaniel Seehofer
Department of General, Visceral, and Transplant Surgery, Charite Campus Virchow, Berlin, Germany
J Surg Res 155:195-200. 2009..Recent investigations have demonstrated a protective effect of curcumin pretreatment during cold ischemia of hepatocytes, but its impact on liver regeneration per se has not been investigated so far...
Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-stateMatthias Glanemann
Department of General, Visceral and Transplantation Surgery, Charit, Campus Virchow Klinikum, Humboldt University Berlin, Berlin, Germany
J Hepatol 38:59-66. 2003....
Hepatic artery thrombosis after adult liver transplantationBarbara J Stange
Department of General, Visceral, and Transplantation Surgery, Charite, Campus Virchow Klinikum, Humboldt University of Berlin, Germany
Liver Transpl 9:612-20. 2003..3%. Our results indicate that HAT is a rare but serious complication after OLT, requiring re-OLT in almost 50% of patients. In particular, conservative treatment modalities may significantly prolong graft survival, thus postponing re-OLT...
Primary permanent arterialization of the portal vein in liver transplantationUtz Settmacher
Department of Surgery, Charite, Campus Virchow, Humboldt University, Augustenburgerplatz 1, 13353 Berlin, Germany
Transpl Int 16:430-3. 2003..The inflow to the portal vein can easily be reduced by the banding of the arterial graft interposition...
Preoperative multidetector row computed tomography for evaluation and assessment of resection criteria in patients with pancreatic massesChristian Grieser
Klinik fur Strahlenheilkunde, Viszeral und Transplantationschirurgie, Campus Virchow Klinikum, Charit é Universit ä tsmedizin Berlin, Berlin, Germany
Acta Radiol 51:1067-77. 2010..The opportunities of modern multidetector computed tomography (MDCT) with image postprocessing can be expected to enhance the diagnostic performance if accurate criteria are elaborated...
Coronary event rates in liver transplant recipients reflect the increased prevalence of cardiovascular risk-factorsOlaf Guckelberger
Department of General, Visceral and Transplantation Surgery, Charite Campus Virchow Klinikum, Berlin, Germany
Transpl Int 18:967-74. 2005..11, 95% CI: 0.53-2.03), nine events were predicted for the transplant population and oppose 10 events observed. Thus, indicating a reflection of increased cardiovascular risk-profiles in corresponding numbers of cardiovascular events...
Prospective randomized comparison between a new mattress technique and Cattell (duct-to-mucosa) pancreaticojejunostomy for pancreatic resectionJan M Langrehr
Department of General, Visceral and Transplanation Surgery, Charité Campus Vichow Klinikum, Humboldt Universitat zu Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
World J Surg 29:1111-9, discussion 1120-1. 2005..Therefore the mattress technique for pancreatojejunostomy seems to be safe and is, in our opinion, well suitable for training schedules in pancreatic surgery...
Ischemic preconditioning and methylprednisolone both equally reduce hepatic ischemia/reperfusion injuryMatthias Glanemann
Department of General, Visceral, and Transplantation Surgery, Charit, Campus Virchow Klinikum, Humboldt University Berlin, Berlin, Germany
Surgery 135:203-14. 2004..Both treatments equally reduced IR-related hepatocellular damage, and, thus, may also be applied equally in surgery involving warm organ hypoxia...
Validation of cardiovascular risk scores in a liver transplant populationOlaf Guckelberger
Department of General, Visceral and Transplantation Surgery, Charité Campus Vichow Klinikum, Berlin, Germany
Liver Transpl 12:394-401. 2006..Furthermore, calibrated PROCAM risk estimates are required to calculate the number of patients needed to treat in the setup of prospective intervention trials...
Long-term results of mycophenolate mofetil as part of immunosuppressive induction therapy after liver transplantationJan M Langrehr
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Germany
Clin Transplant 20:272-83. 2006..In our study, we report on the long-term results of triple induction therapy after orthotopic liver transplantation (OLT), consisting of MMF and low-dose corticosteroids, in combination with either tacrolimus or cyclosporine...
Hepatic resection in liver transplant recipients: single center experience and review of the literatureOlaf Guckelberger
Department of General, Visceral and Transplantation Surgery, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany olaf
Am J Transplant 5:2403-9. 2005..In conclusion, partial graft hepatectomy can be considered a safe and beneficial procedure in selected liver transplant recipients with anatomical limited biliary injury, thereby, preserving scarce donor organs...
Clinical implications of hepatic preservation injury after adult liver transplantationMatthias Glanemann
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, Humboldt University Berlin, Germany
Am J Transplant 3:1003-9. 2003..Severe preservation injury had a tremendous impact on the postoperative clinical course, requiring the maximum medical effort to achieve adequate patient survival...
Heme oxygenase-1 protects human hepatocytes in vitro against warm and cold hypoxiaEda Tuzuner
Department of General, Visceral, and Transplantation Surgery, Universitatsmedizin Berlin, Campus Virchow, Germany
J Hepatol 41:764-72. 2004..Hepatic injury induced by ischemia/reperfusion following surgery, transplantation, or circulatory shock combined with resuscitation is a major clinical problem...
Traumatized liver grafts for organ donation? A single-center experienceRoberta Bova
Universitatsmedizin Berlin, Berlin, Germany
Prog Transplant 19:349-53. 2009..Thus, the use of injured livers may offer new opportunities in transplantation...
Older liver graft transplantation, cholestasis and synthetic graft functionDietmar Borchert
Department of General, Visceral and Transplant Surgery, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin, Germany
Transpl Int 18:709-15. 2005..Donor organ age had no impact on postoperative organ function. We recommend to accept liver grafts from organ donors older than 70 years to expand the donor pool...
Fast tracking in liver transplantation. Immediate postoperative tracheal extubation: feasibility and clinical impactMatthias Glanemann
Department of General, Visceral and Transplantation Surgery, Charite, Campus Virchow Klinikum, University Medical Center, Berlin, Germany
Swiss Med Wkly 137:187-91. 2007..These patients might not be eligible for fast tracking protocols and may be at increased risk of prolonged postoperative mechanical ventilation...
Ischemic preconditioning impairs liver regeneration in extended reduced-size liversChristian Eipel
Department of Experimental Surgery, University of Rostock, Rostock, Germany
Ann Surg 241:477-84. 2005..Further studies are required to finally judge on the harmfulness of IPC in extended liver resection...
