Research Topics
Species | Gesche GenterSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Interleukin 32 promotes hematopoietic progenitor expansion and attenuates bone marrow cytotoxicityAnja Moldenhauer
Institute for Transfusion Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
Eur J Immunol 41:1774-86. 2011..Our findings confirm that the combination of microarrays and gene annotation helps to identify new hematopoietic growth factors...
Optimized culture conditions for the generation of dendritic cells from peripheral blood monocytesA Moldenhauer
Institut fur Transfusionsmedizin, Charite, Humboldt Universitat, Berlin, Germany
Vox Sang 84:228-36. 2003..However, the presence of exogenous animal proteins sets limits for their use in clinical trials. The purpose of this study was to establish a simple, efficient and FBS-free method for the generation of human DCs for clinical application...
Tumor necrosis factor alpha-stimulated endothelium: an inducer of dendritic cell development from hematopoietic progenitors and myeloid leukemic cellsAnja Moldenhauer
Institute for Transfusion Medicine, Charite, Universitätsmedizen Berlin, Berlin, Germany
Stem Cells 22:144-57. 2004..We conclude that, via the action of TNF-alpha, inflamed human endothelium can induce CD34+ and leukemic cells to differentiate into dendritic cells...
Tumor necrosis factor alpha enhances the adenoviral transduction of CD34+ hematopoietic progenitor cellsA Moldenhauer
Institute for Transfusion Medicine, Charite Universitatsmedizin Berlin, Germany
Stem Cells 22:283-91. 2004..This finding correlates with increased Ad capping at the cell surface and suggests an alteration of Ad trafficking...
Histone deacetylase inhibition improves dendritic cell differentiation of leukemic blasts with AML1-containing fusion proteinsAnja Moldenhauer
Institute for Transfusion Medicine and Immunehaematology, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
J Leukoc Biol 76:623-33. 2004..This model system suggests that the Hdi supports the in vitro differentiation of DC from leukemic blasts with AML1-containing fusion proteins...
Immunoadsorption patients with multiple sclerosis: an open-label pilot studyA Moldenhauer
Charite Universitatsmedizin Berlin, Germany
Eur J Clin Invest 35:523-30. 2005..This pilot study was undertaken to determine whether IA might help in secondary progressive and relapsing-remitting multiple sclerosis...
Optimum storage conditions for cord blood-derived hematopoietic progenitor cells prior to isolationA Moldenhauer
Institute for Transfusion Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
Bone Marrow Transplant 40:837-42. 2007..CD34+ cells kept at RT for 48 h had the highest transmigration capacities, which paralleled an increased CXCR-4 expression. Cord blood should be stored at RT before CD34+ isolation and a storage time for 48 h should be preferred to 24 h...
Hematopoietic progenitor cells and interleukin-stimulated endothelium: expansion and differentiation of myeloid precursorsAnja Moldenhauer
Institute for Transfusion Medicine, Charite Universitatsmedizin Berlin, Germany
BMC Immunol 9:56. 2008..HPC were assessed by flow cytometry, colony and cobblestone assays and long-term cultures (LTC) after culturing in the supernatant of EC stimulated by IL-1beta, IL-3 or IL-6...
Histone deacetylase inhibition improves differentiation of dendritic cells from leukemic blasts of patients with TEL/AML1-positive acute lymphoblastic leukemiaKerstin Schmidt
Institute for Transfusion Medicine, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany
J Leukoc Biol 85:563-73. 2009..Therefore, the use of HdI in the differentiation of leukemic DC from patients with TEL/AML1-positive ALL is recommended...
Significance of a T-lymphocytotoxic crossmatch in liver and combined liver-kidney transplantationU P Neumann
Klinik fUr Allgemein, Viszeral und Transplantationschirurgie, Charite, Virchow Klinikum, Humboldt Universitat zu Berlin, Germany
Transplantation 71:1163-8. 2001..The aim of this study was to evaluate the effect of a positive crossmatch on outcome after OLT and combined liver and kidney transplantation (CLKTx)...
Differences in the transmigration of different dendritic cellsAnja Moldenhauer
Institute for Transfusion Medicine, Charite Universitatsmedizin Berlin, Berlin, Germany
Exp Hematol 34:745-52. 2006..Their ability to migrate to the adjacent lymphatic system is relevant since their efficacy does also rely on their potential to interact with lymphocytes...
Neurofascin as a novel target for autoantibody-mediated axonal injuryEmily K Mathey
Department of Medicine and Therapeutics, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, UK
J Exp Med 204:2363-72. 2007..Collectively, these results identify a novel mechanism of immune-mediated axonal injury that can contribute to axonal pathology in MS...
