Christina Fotopoulou

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Incidence of venous thromboembolism in patients with ovarian cancer undergoing platinum/paclitaxel-containing first-line chemotherapy: an exploratory analysis by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    J Clin Oncol 26:2683-9. 2008
  2. ncbi Brain metastases in relapsed epithelial ovarian cancer after chemotherapy with pegylated liposomal doxorubicin
    Nikola Serena Kasprowicz
    Department of Obstetrics and Gynecology, Charite, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 28:1943-6. 2008
  3. ncbi Functional and anatomic results of amnion vaginoplasty in young women with Mayer-Rokitansky-Küster-Hauser syndrome
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Fertil Steril 94:317-23. 2010
  4. ncbi Surgical outcome and survival analysis of young patients with primary epithelial ovarian cancer
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, 13353 Berlin, Germany
    Anticancer Res 29:2809-15. 2009
  5. ncbi Venous thromboembolism in recurrent ovarian cancer-patients: A systematic evaluation of the North-Eastern German Society of Gynaecologic Oncology Ovarian Cancer Study Group (NOGGO)
    C Fotopoulou
    Department of Gynecology and Obstetrics, Charite, University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Thromb Res 124:531-5. 2009
  6. ncbi Systematic evaluation of the intraoperative tumor pattern in patients with borderline tumor of the ovary
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite University Hospital, Campus Virchow Clinic, Berlin, Germany
    Int J Gynecol Cancer 19:1550-5. 2009
  7. ncbi Primary radical surgery in elderly patients with epithelial ovarian cancer: analysis of surgical outcome and long-term survival
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Campus Virchow Clinic, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Int J Gynecol Cancer 20:34-40. 2010
  8. ncbi Prospectively assessed changes in lamotrigine-concentration in women with epilepsy during pregnancy, lactation and the neonatal period
    Christina Fotopoulou
    Department of Obstetrics and Gynecology, Charite University Hospital, Berlin, Germany
    Epilepsy Res 85:60-4. 2009
  9. ncbi External iliac artery ligation due to late postoperative rupture after radical lymphadenectomy for advanced ovarian cancer--two case reports
    C Fotopoulou
    Department of Gynecology, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Eur J Gynaecol Oncol 31:198-200. 2010
  10. ncbi Long-term effects of neovaginal reconstruction with sigmoid loop technique on sexual function and self image in patients with gynecologic malignancies: results of a prospective study
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Gynecol Oncol 111:400-6. 2008

Detail Information

Publications44

  1. ncbi Incidence of venous thromboembolism in patients with ovarian cancer undergoing platinum/paclitaxel-containing first-line chemotherapy: an exploratory analysis by the Arbeitsgemeinschaft Gynaekologische Onkologie Ovarian Cancer Study Group
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    J Clin Oncol 26:2683-9. 2008
    ..Most series reporting on VTE have included different tumor types not differentiating between recurrent or primary disease. Data regarding the actual impact of VTE on primary advanced ovarian cancer (AOC) are limited...
  2. ncbi Brain metastases in relapsed epithelial ovarian cancer after chemotherapy with pegylated liposomal doxorubicin
    Nikola Serena Kasprowicz
    Department of Obstetrics and Gynecology, Charite, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 28:1943-6. 2008
    ..Brain metastases in epithelial ovarian cancer (EOC) occur rarely and are associated with a poor prognosis. No significant risk factors have been identified and no evidence-based treatment guidelines are currently available...
  3. ncbi Functional and anatomic results of amnion vaginoplasty in young women with Mayer-Rokitansky-Küster-Hauser syndrome
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Fertil Steril 94:317-23. 2010
    ..To evaluate the surgical outcome and the long-term anatomic and functional results in young women with Mayer-Rokitansky-Küster-Hauser Syndrome (MRKH) undergoing neovaginal creation with amniotic membranes...
  4. ncbi Surgical outcome and survival analysis of young patients with primary epithelial ovarian cancer
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, 13353 Berlin, Germany
    Anticancer Res 29:2809-15. 2009
    ..The aim of the present study was to evaluate the cancer-related characteristics, intraoperative findings, surgical outcome and survival in this group of young women...
  5. ncbi Venous thromboembolism in recurrent ovarian cancer-patients: A systematic evaluation of the North-Eastern German Society of Gynaecologic Oncology Ovarian Cancer Study Group (NOGGO)
    C Fotopoulou
    Department of Gynecology and Obstetrics, Charite, University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Thromb Res 124:531-5. 2009
    ..Venous thromboembolism (VTE) seems to have a negative prognostic impact in patients with solid tumors including primary ovarian cancer in many series. Only limited contemporary data exist regarding the impact of VTE on ROC...
  6. ncbi Systematic evaluation of the intraoperative tumor pattern in patients with borderline tumor of the ovary
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite University Hospital, Campus Virchow Clinic, Berlin, Germany
    Int J Gynecol Cancer 19:1550-5. 2009
    ..We conducted a systematic evaluation of the macroscopic and microscopic tumor spreads in patients with BOTs with special focus on the diagnosis of invasive and noninvasive lesions...
  7. ncbi Primary radical surgery in elderly patients with epithelial ovarian cancer: analysis of surgical outcome and long-term survival
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Campus Virchow Clinic, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Int J Gynecol Cancer 20:34-40. 2010
    ..The aim of our study was to determine the impact of radical cytoreductive surgery, the cornerstone of clinical management in primary EOC, in this population with special regard to the associated morbidity...
  8. ncbi Prospectively assessed changes in lamotrigine-concentration in women with epilepsy during pregnancy, lactation and the neonatal period
    Christina Fotopoulou
    Department of Obstetrics and Gynecology, Charite University Hospital, Berlin, Germany
    Epilepsy Res 85:60-4. 2009
    ..To prospectively analyse the pharmacokinetics of lamotrigine (LTG) during pregnancy and lactation in a consecutive series of epileptic pregnant women...
  9. ncbi External iliac artery ligation due to late postoperative rupture after radical lymphadenectomy for advanced ovarian cancer--two case reports
    C Fotopoulou
    Department of Gynecology, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Eur J Gynaecol Oncol 31:198-200. 2010
    ..This complication can be managed by unilateral external iliac artery ligation without mandatory subsequent graft interposition or crossover bypass...
  10. ncbi Long-term effects of neovaginal reconstruction with sigmoid loop technique on sexual function and self image in patients with gynecologic malignancies: results of a prospective study
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Gynecol Oncol 111:400-6. 2008
    ..We evaluated the long-term results of sigmoid vaginoplasty in women with gynecologic malignancies after radical pelvic surgery, with specific focus on safety and effects of the procedure on patients' sexuality and self image...
  11. ncbi Preoperative transvaginal ultrasound (TVS) in the description of pelvic tumor spread in endometrial cancer: results of a prospective study
    Christina Fotopoulou
    Department of Obstetrics and Gynecology, Campus Virchow Clinic, Berlin, Germany
    Anticancer Res 28:2453-8. 2008
    ....
  12. ncbi Primary versus interval debulking surgery in advanced ovarian cancer: results from a systematic single-center analysis
    Jalid Sehouli
    Department of Gynecology, Charite, Campus Virchow Clinic University Hospital, Augustenburger Platz 1, Berlin, Germany
    Int J Gynecol Cancer 20:1331-40. 2010
    ..To evaluate the difference in operative and clinical outcome for patients with primary advanced ovarian cancer (AOC) after optimal primary debulking surgery (PDS) versus interval debulking surgery (IDS)...
  13. ncbi Role of secondary cytoreductive surgery in ovarian cancer relapse: who will benefit? A systematic analysis of 240 consecutive patients
    Jalid Sehouli
    Department of Gynecology, Charite University Medical Center Berlin, Berlin, Germany
    J Surg Oncol 102:656-62. 2010
    ..In contrast to primary ovarian cancer, the value of surgery in relapsed-OC (ROC) remains unclear. We evaluated surgical and clinical outcome of secondary cytoreduction in ROC...
  14. ncbi Long-term clinical outcome of pelvic exenteration in patients with advanced gynecological malignancies
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    J Surg Oncol 101:507-12. 2010
    ..We evaluated the outcome of pelvic exenteration in women with locally advanced primary or recurrent gynecological malignancies...
  15. ncbi Value of preoperative transvaginal sonography (TVS) in the description of tumor pattern in ovarian cancer patients: results of a prospective study
    Wolfgang Henrich
    Department of Obstetrics and Gynecology, Campus Virchow Clinic, Berlin, Germany
    Anticancer Res 27:4289-94. 2007
    ..This prospective study evaluates the predictive value of preoperative staging by transvaginal sonography (TVS) in ovarian cancer...
  16. ncbi Impact of obesity on operative morbidity and clinical outcome in primary epithelial ovarian cancer after optimal primary tumor debulking
    Christina Fotopoulou
    Department of Gynecology, European Competence Center for Ovarian Cancer, Charite University Hospital, Berlin, Germany
    Ann Surg Oncol 18:2629-37. 2011
    ..We evaluated operative and clinical outcome in patients operated to treat primary epithelial ovarian cancer (EOC) according to their body mass index (BMI)...
  17. ncbi Systematic pelvic and aortic lymphadenectomy in intermediate and high-risk endometrial cancer: lymph-node mapping and identification of predictive factors for lymph-node status
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Eur J Obstet Gynecol Reprod Biol 149:199-203. 2010
    ..To systematically assess the metastatic pattern of intermediate- and high-risk endometrial cancer in pelvic and para-aortic lymph-nodes and to evaluate risk factors for lymph-node metastases...
  18. ncbi Primary versus secondary cytoreduction for epithelial ovarian cancer: a paired analysis of tumour pattern and surgical outcome
    Elena Ioana Braicu
    European Competence Center for Ovarian Cancer, Department of Gynecology, Charite, Campus Virchow Clinic University Hospital, Berlin, Germany
    Eur J Cancer 48:687-94. 2012
    ..Recurrence rates of Epithelial Ovarian Cancer (EOC) remain high. Aim of the present study was to compare tumour pattern and surgical outcome at primary and secondary tumourdebulking in a paired patients' collective...
  19. ncbi Predictive factors in relapsed ovarian cancer for complete tumor resection
    Blanca Gil-Ibáñez
    Department of Gynecology, Charite Campus Virchow Klinikum, University Medicine of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 31:2583-7. 2011
    ..The aim of this study was to identify predictive factors for complete tumor resection in patients with relapsed ovarian cancer...
  20. ncbi Long term combination treatment with bevacizumab, pegylated liposomal doxorubicin and regional abdominal hyperthermia in platinum refractory ovarian cancer: a case report and review of the literature
    Klaus Pietzner
    Department of Gynecology, Charite University Medicine of Berlin, Berlin, Germany
    Anticancer Res 31:2675-7. 2011
    ..Regional abdominal hyperthermia and bevacizumab are treatment options that have both shown the capacity to improve the results of standard chemotherapy in the platinum-resistant situation, when added to the treatment schedule...
  21. ncbi Clinical outcome of tertiary surgical cytoreduction in patients with recurrent epithelial ovarian cancer
    Christina Fotopoulou
    Department of Gynecology, Charite University Medical Center Berlin, Berlin, Germany
    Ann Surg Oncol 18:49-57. 2011
    ..The value of tertiary cytoreductive surgery (TCS) on overall survival (OS) of patients with relapsed epithelial ovarian cancer (ROC) is not well defined. Aim of the present study was to evaluate the operative and clinical outcome after TCS...
  22. ncbi Maternal characteristics and twin gestation outcomes over 10 years: impact of conception methods
    Christian Bamberg
    Department of Obstetrics, Charite University Medical Center, Berlin, Germany
    Fertil Steril 98:95-101. 2012
    ..To compare maternal characteristics and obstetric outcomes of spontaneously conceived (SC) and after-fertility treatment (FT) twins...
  23. ncbi Systemic changes of tryptophan catabolites via the indoleamine-2,3-dioxygenase pathway in primary cervical cancer
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Virchow Campus Clinic University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 31:2629-35. 2011
    ..Kynurenines are involved in various diseases such as renal failure, sepsis and cancer. We aimed to investigate whether systemic levels of kynurenines are induced in primary cervical cancer (PCC)...
  24. ncbi Regional abdominal hyperthermia combined with systemic chemotherapy for the treatment of patients with ovarian cancer relapse: Results of a pilot study
    Christina Fotopoulou
    Department of Gynaecology, University Hospital, Berlin, Germany
    Int J Hyperthermia 26:118-26. 2010
    ..We performed a prospective phase I/II-study of regional abdominal hyperthermia (RHT) combined with systemic chemotherapy in OCR patients in order to evaluate outcome, efficacy and tolerance...
  25. ncbi Intra-abdominal tumor dissemination pattern and surgical outcome in 214 patients with primary ovarian cancer
    Jalid Sehouli
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital, Augustenburger Platz 1, Berlin 13353, Germany
    J Surg Oncol 99:424-7. 2009
    ..We performed a systematic evaluation of tumor pattern and surgical outcome in 214 consecutive patients with primary ovarian cancer...
  26. ncbi Quality of life and sexuality of patients after treatment for gynaecological malignancies: results of a prospective study in 55 patients
    Adak Pilger
    European Competence Centre for Ovarian Cancer, Department of Gynecology, Charite, Campus Virchow Clinic University of Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 32:5045-9. 2012
    ..To assess the sexuality and quality of life (QoL) of women with gynaecological malignancies after multimodal therapy...
  27. ncbi Correlation of midtrimester amniotic fluid cytokine concentrations with adverse pregnancy outcome in terms of spontaneous abortion, preterm birth, and preeclampsia
    Christian Bamberg
    Department of Obstetrics, Charite University Hospital, Berlin, Germany
    J Matern Fetal Neonatal Med 25:812-7. 2012
    ..To assess midtrimester amniotic fluid concentrations of three major proinflammatory cytokines (IL-6, IL-8, and TNF-α) in asymptomatic pregnancies with adverse outcomes...
  28. ncbi Reconstructive surgical management of cryptomenorrhea because of complex uterovaginal malformations with duplicate uterus and complete vaginal agenesis
    Christina Fotopoulou
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Clinic, University Hospital Berlin, Berlin, Germany
    Fertil Steril 94:2329.e13-6. 2010
    ..To describe the surgical reconstructive options in cases of cryptomenorrhea because of an obstructed functioning uterus with upper and lower vaginal agenesis...
  29. ncbi Proteomic analysis of midtrimester amniotic fluid to identify novel biomarkers for preterm delivery
    Christina Fotopoulou
    Department of Gynecology, Berlin Centrum for Regenerative Therapies, Charite University Hospital, Berlin, Germany
    J Matern Fetal Neonatal Med 25:2488-93. 2012
    ..The aim of this study was to identify possible biomarkers for preterm delivery by analyzing midtrimester amniotic fluid...
  30. ncbi Additive growth inhibition after combined treatment of 2-methoxyestradiol and conventional chemotherapeutic agents in human pancreatic cancer cells
    Christina Fotopoulou
    Department of Gynecology, Charite, Universitatsmedizin Berlin, 13353 Berlin, Germany
    Anticancer Res 30:4619-24. 2010
    ..The aim of this study was to determine whether a combination of 2-ME2 with other established chemotherapeutic compounds increases its tumor-inhibiting effect on human PC cells...
  31. ncbi HE4 Tissue Expression in Borderline Ovarian Tumors: A Pilot Study by the Tumorbank Ovarian Cancer Network
    Mani Nassir
    Department of Gynecology, Campus Virchow Clinic, Charité Medical University Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 33:1673-7. 2013
    ..Aim: Our purpose was to analyze the tissue expression of human epididymis protein-4 (HE4) in borderline tumors of the ovary (BOT) and to correlate it with histological subtypes and clinical features...
  32. ncbi Clinical outcome of patients with advanced ovarian cancer after resection of liver metastases
    Ulf P Neumann
    Departments of General, Charite, Campus Virchow Clinic, University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 32:4517-21. 2012
    ..Hepatic resection has become the standard treatment for patients with primary or metastatic liver malignancies. The aim of our study was to evaluate the clinical outcome of hepatic resection in patients with advanced ovarian cancer (AOC)...
  33. ncbi First surgical experience of intraperitoneal treatment with the trifunctional antibody catumaxomab (anti-EpCam x anti-CD3) for epithelial ovarian cancer
    Georgios Papanikolaou
    Department of Gynecology, Virchow Campus Clinic, Charite University Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 31:2603-8. 2011
    ..p. catumaxomab application. Therefore we analyzed the surgical outcome of EOC patients, previously treated with i.p. catumaxomab, with special focus on the effect on adhesion formation and morbidity...
  34. ncbi What are the individual perceptions of patients with borderline tumours of the ovary in regard to pathogenesis and prognosis? A structured survey on 60 women
    Christina Fotopoulou
    Department of Gynecology, Charité University of Berlin, Berlin, Germany
    J Psychosom Obstet Gynaecol 31:265-72. 2010
    ..However, patients do not expect to die of BOT. There is a high need to intensify information process regarding BOT. Future trials are warranted to evaluate whether this may substantially influence the patients' perspectives...
  35. ncbi Increased indoleamine 2,3-dioxygenase (IDO) activity and elevated serum levels of tryptophan catabolites in patients with chronic kidney disease: a possible link between chronic inflammation and uraemic symptoms
    Jörg C Schefold
    Department of Nephrology and Intensive Care, Charite University Medicine, Campus Virchow Clinic, Berlin, Germany
    Nephrol Dial Transplant 24:1901-8. 2009
    ..Here we investigate Trp catabolism, IDO activity and the role of inflammation in moderate to very severe CKD and haemodialysis...
  36. ncbi Angle of progression measurements of fetal head at term: a systematic comparison between open magnetic resonance imaging and transperineal ultrasound
    Christian Bamberg
    Department of Obstetrics, Charite University Hospital, Berlin, Germany
    Am J Obstet Gynecol 206:161.e1-5. 2012
    ..During labor, transperineal sonography is increasingly used to evaluate fetal head descent. The aim of this study was to compare the angle of progression assessed by open magnetic resonance imaging (MRI) vs transperineal ultrasound...
  37. ncbi Evidence-based perioperative management: strategic shifts in times of fast track surgery
    Sascha Santosh Chopra
    Department of General, Visceral and Transplantation Surgery, Charite Campus Virchow Clinic, University Medicine Berlin, 13353 Berlin, Germany
    Anticancer Res 29:2799-802. 2009
    ..However, despite the evidence-based superiority, widespread implementation has not yet occurred. The aim of this review is to highlight and discuss current changes and to show future perspectives of perioperative treatment strategies...
  38. ncbi Value of tertiary cytoreductive surgery in epithelial ovarian cancer: an international multicenter evaluation
    Christina Fotopoulou
    Department of Gynaecology, European Competence Center for Ovarian Cancer, Charite, Campus Virchow Clinic, University Hospital, Berlin, Germany
    Ann Surg Oncol 20:1348-54. 2013
    ..The aim of the present study was to evaluate the outcome of EOC-patients who underwent tertiary cytoreductive surgery (TCS) and to identify prognostic markers for complete tumor resection and survival...
  39. ncbi Treatment decision-making processes in the systemic treatment of ovarian cancer: review of the scientific evidence
    Hrvoje Luketina
    Department of Gynecology, European Competence Center for Ovarian Cancer, Charite University Medicine Berlin, Virchow Clinic Campus, Berlin, Germany
    Anticancer Res 32:4085-90. 2012
    ..Therefore, we conducted a review of the current literature regarding the decision-making process concerning the systemic therapy in patients with advanced ovarian cancer...
  40. ncbi Fertility-sparing surgery in early epithelial ovarian cancer: a viable option?
    Christina Fotopoulou
    Department of Gynecology, European Competence Center for Ovarian Cancer, Campus Virchow Clinic, Charite University Hospital, 13353 Berlin, Germany
    Obstet Gynecol Int 2012:238061. 2012
    ....
  41. ncbi Chemotherapy-induced dermatological toxicity: frequencies and impact on quality of life in women's cancers. Results of a prospective study
    Mark Hackbarth
    Department of Gynecology and Obstetrics, Charite, Campus Virchow Klinikum, University Hospital, Berlin, Germany
    Support Care Cancer 16:267-73. 2008
    ..The study aimed to determine the prevalence of dermatological side effects and its impact on quality of life in patients receiving systemic chemotherapy for women's cancers...
  42. ncbi Mid-trimester amniotic fluid concentrations of the proinflammatory cytokines IL-6, IL-8, TNF-α, and lipopolysaccharide binding protein in normal pregnancies: a prospective evaluation according to parity, gestational age, and fetal gender
    Christian Bamberg
    Department of Obstetrics, Charite University Hospital, Berlin, Germany
    J Perinat Med 39:403-9. 2011
    ....
  43. ncbi Clostridium septicum Can Cause Distant Myonecrosis in Patients with Ovarian Cancer
    Sarah Zurmeyer
    Department für Gynecological Oncology Charite, Campus Virchow Hospital, Augustenburger Platz 1, 13353 Berlin, Germany
    Anticancer Res 33:1585-9. 2013
    ..The diagnosis was gas gangrene due to Clostridium septicum. Because it is a rare and severe disease and the time slot in which therapeutic measures can be taken is narrow, we discuss clinical symptoms and therapeutic options...
  44. ncbi Treatment with granulocyte-macrophage colony-stimulating factor is associated with reduced indoleamine 2,3-dioxygenase activity and kynurenine pathway catabolites in patients with severe sepsis and septic shock
    Joerg C Schefold
    Department of Nephrology and Intensive Care Medicine, Charite University Medicine, Campus Virchow, Berlin, Germany
    Scand J Infect Dis 42:164-71. 2010
    ..005, r = -0.28) in the overall samples group. Thus, GM-CSF therapy is associated with decreased IDO activity and reduced kynurenine pathway catabolites in sepsis. This may be due to an improved antibacterial defence...