T Fischer

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Vascular endothelial growth factor receptor 2-specific microbubbles for molecular ultrasound detection of prostate cancer in a rat model
    Thomas Fischer
    Department of Radiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Invest Radiol 45:675-84. 2010
  2. ncbi request reprint [Renal transplant: color duplex ultrasound and contrast-enhanced ultrasound in the evaluation of the early postoperative phase and surgical complications]
    T Fischer
    Institut fur Radiologie, Charite Campus Mitte, Universitatsmedizin Berlin
    Rofo 178:1202-11. 2006
  3. ncbi request reprint [Characterization of sonographically detected breast lesions using three-dimensional data sets]
    T Fischer
    Institut fur Radiologie, Charite Universitatsmedizin Berlin
    Rofo 178:1224-34. 2006
  4. ncbi request reprint [Ultrasound at the bedside: does a portable ultrasound device save time?]
    T Fischer
    Institut fur Radiologie, Charite Campus Mitte, Medizinische Fakultat der Humboldt Universitat zu Berlin, Germany
    Ultraschall Med 23:311-4. 2002
  5. ncbi request reprint [Image quality and detection of pathology by ultrasound: comparison of B-mode ultrasound with photopic imaging and tissue harmonic imaging alone and in combination]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Humboldt Universitat Berlin
    Rofo 174:1313-7. 2002
  6. ncbi request reprint [Use of state-of-the-art ultrasound techniques in diagnosing sarcoidosis of the salivary glands (Heerfordt's syndrome)]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin
    HNO 51:394-9. 2003
  7. ncbi request reprint Arrival time parametric imaging: a new ultrasound technique for quantifying perfusion of kidney grafts
    T Fischer
    Dept of Radiology, Charite Universitatsmedizin Berlin, Campus Charite Mitte
    Ultraschall Med 29:418-23. 2008
  8. ncbi request reprint The use of contrast-enhanced US in renal transplant: first results and potential clinical benefit
    Thomas Fischer
    Department of Radiology, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Eur Radiol 15:E109-16. 2005
  9. ncbi request reprint Assessment of unspecific near-infrared dyes in laser-induced fluorescence imaging of experimental arthritis
    Thomas Fischer
    Department of Radiology, Charite, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Acad Radiol 13:4-13. 2006
  10. ncbi request reprint [A new method for standardized diagnosis following renal transplantation. Ultrasound with contrast enhancement]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Campus Mitte, Universitatsmedizin, Schumannstrtasse 20 21, 10098 Berlin
    Urologe A 45:38-45. 2006

Detail Information

Publications73

  1. doi request reprint Vascular endothelial growth factor receptor 2-specific microbubbles for molecular ultrasound detection of prostate cancer in a rat model
    Thomas Fischer
    Department of Radiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Invest Radiol 45:675-84. 2010
    ..To investigate whether rat prostate cancer can be detected by means of molecular ultrasound (US) using target-specific microbubbles versus a nonspecific contrast agent...
  2. ncbi request reprint [Renal transplant: color duplex ultrasound and contrast-enhanced ultrasound in the evaluation of the early postoperative phase and surgical complications]
    T Fischer
    Institut fur Radiologie, Charite Campus Mitte, Universitatsmedizin Berlin
    Rofo 178:1202-11. 2006
    ..Initial studies show that efficient and early diagnosis of rejection is possible. Surgical complications like perfusion defects or hematoma can also be identified...
  3. ncbi request reprint [Characterization of sonographically detected breast lesions using three-dimensional data sets]
    T Fischer
    Institut fur Radiologie, Charite Universitatsmedizin Berlin
    Rofo 178:1224-34. 2006
    ..The individual criteria were correlated with the histological findings and they were ranked according to their significance for lesion characterization in both 3D US and 2D US...
  4. ncbi request reprint [Ultrasound at the bedside: does a portable ultrasound device save time?]
    T Fischer
    Institut fur Radiologie, Charite Campus Mitte, Medizinische Fakultat der Humboldt Universitat zu Berlin, Germany
    Ultraschall Med 23:311-4. 2002
    ..To prospectively determine whether the use of a portable ultrasound device results in a detectable reduction of the time required for acute ultrasound (US) assessment at the bedside...
  5. ncbi request reprint [Image quality and detection of pathology by ultrasound: comparison of B-mode ultrasound with photopic imaging and tissue harmonic imaging alone and in combination]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Humboldt Universitat Berlin
    Rofo 174:1313-7. 2002
    ..To determine the accuracy of photopic imaging (PI) in detecting pathology by ultrasound (US) and to assess the image quality in direct comparison with conventional B-mode ultrasound and tissue harmonic imaging (THI)...
  6. ncbi request reprint [Use of state-of-the-art ultrasound techniques in diagnosing sarcoidosis of the salivary glands (Heerfordt's syndrome)]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Humboldt Universitat zu Berlin
    HNO 51:394-9. 2003
    ..The parotid gland is a rare site of sarcoidosis (6% of all cases). The role of state-of-the-art ultrasound techniques in the diagnostic assessment of parotid sarcoidosis (Heerfordt's syndrome) is presented...
  7. ncbi request reprint Arrival time parametric imaging: a new ultrasound technique for quantifying perfusion of kidney grafts
    T Fischer
    Dept of Radiology, Charite Universitatsmedizin Berlin, Campus Charite Mitte
    Ultraschall Med 29:418-23. 2008
    ..Evaluation of a new standardised ultrasound (US) technique for diagnosis of acute rejection of kidney grafts...
  8. ncbi request reprint The use of contrast-enhanced US in renal transplant: first results and potential clinical benefit
    Thomas Fischer
    Department of Radiology, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Eur Radiol 15:E109-16. 2005
    ....
  9. ncbi request reprint Assessment of unspecific near-infrared dyes in laser-induced fluorescence imaging of experimental arthritis
    Thomas Fischer
    Department of Radiology, Charite, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Acad Radiol 13:4-13. 2006
    ..The aim of the study is to evaluate in vivo fluorescence imaging of experimental inflammatory joint disease by applying two different near-infrared (NIR) dyes in a model of Borrelia-induced Lyme arthritis...
  10. ncbi request reprint [A new method for standardized diagnosis following renal transplantation. Ultrasound with contrast enhancement]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Campus Mitte, Universitatsmedizin, Schumannstrtasse 20 21, 10098 Berlin
    Urologe A 45:38-45. 2006
    ..This method is also helpful to detect and control acute rejections and to better visualize hematomas, deficits of perfusion, and tumors...
  11. ncbi request reprint Diagnosis of Heerfordt's syndrome by state-of-the-art ultrasound in combination with parotid biopsy: a case report
    T Fischer
    Department of Radiology, Universitatsklinikum Charite, Campus Charite Mitte, Humboldt Universitat zu Berlin, Schumannstrasse 20 21, 10098 Berlin, Germany
    Eur Radiol 12:134-7. 2002
    ..In conclusion, state-of-the-art ultrasound with the option of obtaining a biopsy at low risk is a useful procedure for diagnosing unclear pathology of the parotid gland with rapid histological confirmation...
  12. ncbi request reprint Improved diagnosis of early kidney allograft dysfunction by ultrasound with echo enhancer--a new method for the diagnosis of renal perfusion
    Thomas Fischer
    Institut für Radiologie Charité, Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, 10098 Berlin, Germany
    Nephrol Dial Transplant 21:2921-9. 2006
    ..We, therefore, performed a prospective study to compare the value of ultrasound contrast media (USCM) with conventional US in the diagnosis of early allograft dysfunction...
  13. doi request reprint Detection of rheumatoid arthritis using non-specific contrast enhanced fluorescence imaging
    Thomas Fischer
    Institut fur Radiologie, Charite University Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Acad Radiol 17:375-81. 2010
    ....
  14. ncbi request reprint [Sacroiliitis in children with spondyloarthropathy: therapeutic effect of CT-Guided intra-articular corticosteroid injection]
    T Fischer
    Institut fur Radiologie, Universitatsklinikum Charite, Campus Mitte, Humboldt Universitat zu Berlin
    Rofo 175:814-21. 2003
    ....
  15. ncbi request reprint Early postoperative ultrasound of kidney transplants: evaluation of contrast medium dynamics using time-intensity curves
    T Fischer
    Charite University Hospital, Campus Charite Mitte, Humboldt Universitat zu Berlin, Department of Radiology, Berlin
    Rofo 176:472-7. 2004
    ..To evaluate kidney recipients in the early posttransplant phase by semiquantitative analysis of the arterial arrival of ultrasound (US) contrast medium using time-intensity curves...
  16. ncbi request reprint [Transarterial embolization for uterine fibroids: clinical success rate and results of magnetic resonance imaging]
    T J Kröncke
    Institut fur Radiologie, Charite Universitatsmedizin Berlin, Campus Mitte, Humboldt Universitat zu Berlin
    Rofo 177:89-98. 2005
    ..To analyze the clinical success rate and the findings of magnetic resonance imaging (MRI) after uterine artery embolization of symptomatic leiomyomas (fibroids) of the uterus...
  17. ncbi request reprint [Magnetic resonance tomography of sacroiliitis: anatomy, histological pathology, MR-morphology, and grading]
    K G A Hermann
    Institut fur Radiologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte
    Radiologe 44:217-28. 2004
    ..Values of the 4 quadrants are summed to an activity score (range 0-16). The new grading system is proposed to facilitate the examination and shorten image interpretation time...
  18. ncbi request reprint Near monochromatic X-rays for digital slot-scan mammography: initial findings
    Felix Diekmann
    Department of Radiology, University Hospital Charite, Schumannstrasse 20 21, 10117 Berlin, Germany
    Eur Radiol 14:1641-6. 2004
    ..The results suggest that monochromatization has a potential for improving image quality or decreasing dose in X-ray mammography...
  19. ncbi request reprint [Dose reduction through gridless technique in digital full-field mammography]
    F Diekmann
    Institut fur Radiologie, Universitatsklinikum Charite, Berlin
    Rofo 175:769-74. 2003
    ..To determine the role of the scatter grid in digital full-field mammography with respect to image quality and dose and to compare the experimental results with initial clinical experience...
  20. ncbi request reprint Real-time elastography--an advanced method of ultrasound: First results in 108 patients with breast lesions
    A Thomas
    Department of Obstetrics and Gynecology, Charite Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Ultrasound Obstet Gynecol 28:335-40. 2006
    ..To evaluate whether real-time elastography, a new, non-invasive method for the diagnosis of breast cancer, improves the differentiation and characterization of benign and malignant breast lesions...
  21. ncbi request reprint [Ten years of laparoscopic living kidney donation. From an extravagant to a routine procedure]
    M Giessing
    Klinik für Urologie, Campus Mitte, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10098 Berlin
    Urologe A 45:46-52. 2006
    ..For the operating surgeon multiple developments have expanded the technical armentarium. LDN is safe for donor, recipient and kidney. Central issue of an optimal LDN is sufficient experience with laparoscopic urological techniques...
  22. ncbi request reprint Transrectal broadband-Doppler sonography with intravenous contrast medium administration for prostate imaging and biopsy in men with an elevated PSA value and previous negative biopsies
    Kasra Taymoorian
    Departments of Urology, Charite, Universitatsmedizin Berlin, Germany
    Anticancer Res 27:4315-20. 2007
    ..THE AIM of this study was to determine the prostate cancer detection rate of targeted biopsy using contrast-enhanced ultrasound (US) in patients with elevated prostate specific antigen (PSA) levels and previous negative biopsy...
  23. doi request reprint [Detection of prostate cancer by real-time MR/ultrasound fusion-guided biopsy: 3T MRI and state of the art sonography]
    T Durmus
    Institut fur Radiologie, Universitatsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    Rofo 185:428-33. 2013
    ..The aim of this study is to evaluate whether prostate cancer detection rates of transrectal ultrasound (TRUS)-guided biopsy may be improved by an image fusion of state-of-the-art ultrasound (CEUS, elastography) and MR (T2w, DWI) imaging...
  24. ncbi request reprint [Contribution of MRI in diagnosis of urinary stress incontinence without concomitant urogenital prolapse]
    D Beyersdorff
    Institut fur Radiologie, Charite, Humboldt Universitat zu Berlin
    Rofo 173:601-5. 2001
    ..To detect pathomorphological changes of the pelvic floor, the vagina, and the urethra by MR imaging in patients with stress urinary incontinence in the absence of organ descent compared with findings in 10 healthy controls...
  25. ncbi request reprint [Endovenous treatment of primary varicose veins: an effective and safe therapeutic alternative to stripping?]
    C Kluner
    Institut fur Radiologie, Charite Universitatsmedizin Berlin, Campus Mitte
    Rofo 177:179-87. 2005
    ....
  26. ncbi request reprint [Technical success rate, peri-interventional complications and radiation exposure of the transarterial embolization for leiomyomas of the uterus]
    T J Kröncke
    Institut fur Radiologie, Universitätsklinikum Charité Campus Mitte, Humboldt Universitat zu Berlin
    Rofo 176:580-9. 2004
    ..To analyze the technical success rate, incidence and type of peri-interventional complications, and radiation exposure of uterine artery embolization (UAE) in symptomatic leiomyomas of the uterus...
  27. ncbi request reprint Systemic eight-cycle anti-CD20 monoclonal antibody (rituximab) therapy in primary cutaneous B-cell lymphomas--an applicational observation
    S Gellrich
    Department of Dermatology, Venerology and Allergy, Medical Faculty Charité, Humboldt University Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Br J Dermatol 153:167-73. 2005
    ..So far it has been unclear whether an extended duration of therapy leads to a benefit for the patients with PCBCL...
  28. ncbi request reprint [Image quality and characterisation of sonographically detected breast lesions: comparison of tissue harmonic imaging alone and in combination with frequency compounding]
    A Thomas
    Klinik fur Gynakologie und Geburtshilfe, Universitat Berlin
    Ultraschall Med 28:387-93. 2007
    ..To determine the accuracy of frequency compounding (FC) in detection and characterisation of breast lesions by ultrasound (US) and to assess the image quality in direct comparison with tissue harmonic imaging (THI)...
  29. doi request reprint [Germ cell tumors - documentation of diagnosis and therapy by means of a web-based modular database system]
    N Schreiter
    Die Institutsangaben sind am Ende des Beitrags gelistet
    Aktuelle Urol 39:442-7. 2008
    ..The aim of this study was to develop an internet platform to document the quality of individual sections of treatment for patients with germ cell tumours in Berlin and to improve the therapy in conformity with the S2 guidelines...
  30. ncbi request reprint Interactions of metarhodopsin II. Arrestin peptides compete with arrestin and transducin
    A Pulvermüller
    Institut fur Medizinische Physik und Biophysik, Humboldt Universitat zu Berlin, Universitatsklinikum Charite, Schumannstrasse 20 21, 10098 Berlin, Germany
    J Biol Chem 275:37679-85. 2000
    ..The arrestin sites are located in both the C- and N-terminal domains of the arrestin structure...
  31. ncbi request reprint [Pain management in the elderly--1: Recognizing and understanding the etiologies of pain]
    Kirsten Neumann
    Universitatsmedizin Berlin, Graduiertenkolleg Multimorbidität im Alter und ausgewählte Pflegeprobleme
    Pflege Z 58:287-91. 2005
  32. ncbi request reprint Rheumatoid arthritis of the shoulder joint: comparison of conventional radiography, ultrasound, and dynamic contrast-enhanced magnetic resonance imaging
    Kay Geert A Hermann
    Department of Radiology, Charite, Berlin, Germany
    Arthritis Rheum 48:3338-49. 2003
    ..To determine the role of ultrasound and magnetic resonance imaging (MRI) compared with conventional radiography in the detection of chronic and acute inflammatory manifestations of rheumatoid arthritis (RA) of the shoulder joint...
  33. doi request reprint Significant differentiation of focal breast lesions: calculation of strain ratio in breast sonoelastography
    Anke Thomas
    Department of Obstetrics and Gynecology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Acad Radiol 17:558-63. 2010
    ..The aim of this study was to compare elastography and B-mode ultrasound to determine whether the calculation of strain ratios (SRs) can further improve the differentiation of focal breast lesions...
  34. ncbi request reprint Truncus arteriosus communis in a midtrimester fetus: comparison of prenatal ultrasound and MRI with postmortem MRI and autopsy
    Matthias R Mühler
    Department of Radiology, Charite, CCM, Schumannstrasse 20 21, 10117 Berlin, Germany
    Eur Radiol 14:2120-4. 2004
    ..Therefore, MRI should be used more often in fetal cardiology, although it still must be further developed...
  35. ncbi request reprint Real-time sonoelastography performed in addition to B-mode ultrasound and mammography: improved differentiation of breast lesions?
    Anke Thomas
    Department of Obstetrics and Gynecology, Chariteplatz, Charite Universitatsmedizin, Berlin 10117, Germany
    Acad Radiol 13:1496-504. 2006
    ..The goal of the present study was to compare the sensitivity and specificity of elastography with that of B-mode ultrasound (US) and mammography...
  36. ncbi request reprint Relevance of depth resolution for cerebral blood flow monitoring by near-infrared spectroscopic bolus tracking during cardiopulmonary bypass
    Jens Steinbrink
    Clinic of Neurology, German Heart Institute, Berlin, Germany
    J Thorac Cardiovasc Surg 132:1172-8. 2006
    ..Contamination of the cerebral signal by contamination from overlaying extracerebral tissue, however, has been proposed to reduce sensitivity and cerebral selectivity of this promising technique...
  37. ncbi request reprint [Targeted management of challenging behavior in persons with dementia: the "Serial Trial Intervention" (STI)]
    Thomas Fischer
    Charite Universitatsmedizin Berlin, Arbeitsgruppe Pflegerische Versorgungsforschung, Berlin
    Pflege Z 60:370-3. 2007
  38. ncbi request reprint Real-time sonoelastography of the cervix: tissue elasticity of the normal and abnormal cervix
    Anke Thomas
    Department of Gynecology and Obstetrics, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, G 10117 Berlin, Germany
    Acad Radiol 14:193-200. 2007
    ..First study to investigate the basic tissue elastic properties of the cervix in pre- and postmenopausal healthy women and to compare these normal findings with the results in a group of patients with focal pathology of the cervix...
  39. ncbi request reprint Patients with a history of elevated prostate-specific antigen levels and negative transrectal US-guided quadrant or sextant biopsy results: value of MR imaging
    Dirk Beyersdorff
    Department of Radiology, Charite, Humboldt Universitat, Schumannstrasse 20 21, 10117 Berlin, Germany
    Radiology 224:701-6. 2002
    ....
  40. ncbi request reprint [Scales for pain assessment in persons with severe dementia: aids for observation]
    Thomas Fischer
    Arbeitsgruppe Pflegerische Versorgungsforschung, Charite Universitatsmedizin, Berlin, Germany
    Pflege Z 60:308-11. 2007
  41. ncbi request reprint Tissue Doppler and strain imaging for evaluating tissue elasticity of breast lesions
    Anke Thomas
    Department of Obstetrics and Gynecology, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Acad Radiol 14:522-9. 2007
    ..The present study served to investigate whether the specificity of B-mode ultrasound (US) can be improved by combining B-mode imaging with tissue Doppler imaging (TDI) and offline analysis of tissue strain imaging (TSI)...
  42. ncbi request reprint [Pain management in the elderly--2: Recognizing and assessing pain accurately]
    Thomas Fischer
    Charite, Universitatsmedizin Berlin, Graduiertenkolleg Multimorbidität im Alter und ausgewählte Pflegeprobleme, Berlin
    Pflege Z 58:355-8. 2005
  43. ncbi request reprint Magnetic resonance imaging of the upper abdomen using a free-breathing T2-weighted turbo spin echo sequence with navigator triggered prospective acquisition correction
    Christian Klessen
    Department of Radiology, Charité Universitary Medicine Berlin, Campus Charite Mitte, Humboldt University of Berlin, Berlin, Germany
    J Magn Reson Imaging 21:576-82. 2005
    ....
  44. doi request reprint Deficits in pain treatment in nursing homes in Germany: a cross-sectional study
    M Kölzsch
    Institute of Clinical Pharmacology and Toxicology, Charite Universitatsmedizin Berlin, D 10117, Berlin, Germany
    Eur J Pain 16:439-46. 2012
    ..Current knowledge about the quality and appropriateness of pharmacological pain treatment in nursing home residents (NHR), particularly in NHR with moderate to severe cognitive impairment, is poor...
  45. doi request reprint [Magnetic resonance elastography of the liver]
    I Sack
    Institut fur Radiologie, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Chariteplatz 1, Berlin, Germany
    Radiologe 52:738-44. 2012
    ..The early detection of liver fibrosis remains a major challenge in medical imaging...
  46. doi request reprint Intraoperative specimen radiography in patients with nonpalpable malignant breast lesions
    C Schmachtenberg
    Radiology, Charite, Campus Mitte, Berlin
    Rofo 184:635-42. 2012
    ..Specimen mammography of nonpalpable wire-localized breast lesions is the standard in breast-conserving surgery. The aim of this study was to evaluate the reliability of intraoperative 2-view specimen mammography in different cancer types...
  47. ncbi request reprint Evaluation of post-cardiopulmonary bypass coagulation disorders by differential diagnosis with a multichannel modified thromboelastogram: a pilot investigation
    A Koster
    Department for Anesthesia, Deutsches Herzzentrum, Berlin, Germany
    J Extra Corpor Technol 33:153-8. 2001
    ..However, elaboration is desirable, and larger clinical trials are necessary for a final evaluation of the protocol...
  48. doi request reprint [Patient view in the assessment of quality of life in old age: potentials and limits]
    M Holzhausen
    Institut für Biometrie und Klinische Epidemiologie, Charite Universitatsmedizin Berlin, Luisenstrasse 65, Berlin, Germany
    Z Gerontol Geriatr 42:355-9. 2009
    ..All three approaches highlighted potentials for an extended integration of the patient's perspective in the assessment and evaluation of their quality of life...
  49. ncbi request reprint Correction of cor triatriatum sinistrum in a Jehovah's Witness infant
    V Alexi-Meskishvili
    Department of Cardiovascular and Thoracic Surgery and Department of Congenital Heart Disease, Augustenburger Platz 1, 13353, Berlin, Germany
    Eur J Cardiothorac Surg 18:724-6. 2000
    ..5 g/dl. The infant was extubated on the same day and discharged from our institution on the eighth day after surgery. Two years after surgery the child is in sinus rhythm and is developing well...
  50. ncbi request reprint The plasma supplemented modified activated clotting time for monitoring of heparinization during cardiopulmonary bypass: a pilot investigation
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Charite, Campus Virchow, Augustenburger Platz 1, 13353 Berlin, Germany
    Anesth Analg 95:26-30, table of contents. 2002
    ..The improved correlation most likely results from a correction of the effects of the impairment of the coagulation system caused by hemodilution and consumption of procoagulants on extracorporeal surfaces...
  51. ncbi request reprint Hemostatic activation and inflammatory response during cardiopulmonary bypass: impact of heparin management
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum, and Institute of Physiology, Freie Universitat, Berlin, Germany
    Anesthesiology 97:837-41. 2002
    ....
  52. ncbi request reprint Can student tutors act as examiners in an objective structured clinical examination?
    Jean Francois Chenot
    Department of General Practice, University of Gottingen, Gottingen, Germany
    Med Educ 41:1032-8. 2007
    ..Senior medical students may be able to support faculty staff to assess their peers. The aim of this study is to assess the reliability of student tutors as OSCE examiners and their acceptance by their peers...
  53. ncbi request reprint The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome-negative cells
    Michael W N Deininger
    Division of Hematology and Medical Oncology, Oregon Health and Science University Cancer Institute, Portland, Oregon 97239, USA
    Cancer 110:1509-19. 2007
    ..In some patients, CCA/Ph-negative status was associated with myelodysplasia or acute myeloid leukemia. The objective of the current study was to determine the prognostic impact of CCA/Ph-negative cells...
  54. ncbi request reprint Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia
    Hagop Kantarjian
    M D Anderson Cancer Center, Houston, TX 77030, USA
    N Engl J Med 346:645-52. 2002
    ..Chronic myelogenous leukemia (CML) is caused by the BCR-ABL tyrosine kinase, the product of the Philadelphia chromosome. Imatinib mesylate, formerly STI571, is a selective inhibitor of this kinase...
  55. doi request reprint [Data monitoring committees. Third pillar in the methodical conduct of clinical trials]
    Thomas Fischer
    Bundesinstitut fur Arzneimittel und Medizinprodukte, Kurt Georg Kiesinger Allee 3, Bonn, BRD
    Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 51:793-6. 2008
    ....
  56. ncbi request reprint Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia
    Rudiger Hehlmann
    III Medizinische Universitätsklinik, Medizinische Fakultät Mannheim der Universität Heidelberg, Wiesbadener Strasse 7 11, 63805 Mannheim, Germany
    Blood 109:4686-92. 2007
    ..032). The general recommendation of HSCT as first-line treatment option in chronic phase CML can no longer be maintained. It should be replaced by a trial with modern drug treatment first...
  57. ncbi request reprint A phase I study of intravenous LBH589, a novel cinnamic hydroxamic acid analogue histone deacetylase inhibitor, in patients with refractory hematologic malignancies
    Francis Giles
    Department of Leukemia, University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Clin Cancer Res 12:4628-35. 2006
    ..LBH589 is a novel histone deacetylase inhibitor that inhibits proliferation and induces apoptosis in tumor cell lines. In this phase I study, LBH589 was administered i.v. as a 30-minute infusion on days 1 to 7 of a 21-day cycle...
  58. ncbi request reprint Effectiveness of a powered toothbrush compared with a manual toothbrush for orthodontic patients with fixed appliances
    Annerose Borutta
    Department of Preventive Dentistry, Friedrich Schiller University of Jena, Centre for Dentistry, Jena, Germany
    J Clin Dent 13:131-7. 2002
    ..The findings were for both whole mouth and partial mouth assessments. In accordance with previous studies, it was demonstrated that the use of a powered toothbrush can be recommended for orthodontic patients with fixed appliances...
  59. pmc Influence of patient symptoms and physical findings on general practitioners' treatment of respiratory tract infections: a direct observation study
    Thomas Fischer
    Department of General Practice, Georg August University, Goettingen, Germany
    BMC Fam Pract 6:6. 2005
    ..The influence of patient complaints and physical examination findings on GPs' prescribing behaviour was mostly investigated by indirect methods such as questionnaires...
  60. ncbi request reprint The incidence of myelofibrosis in essential thrombocythaemia, polycythaemia vera and chronic idiopathic myelofibrosis: a retrospective evaluation of sequential bone marrow biopsies
    Andreas Kreft
    Institut fü Pathologie, Klinikum Johannes Gutenberg Universitä Mainz, Mainz, Deutschland
    Acta Haematol 113:137-43. 2005
    ..9 years, 34 of the 79 patients with CIMF (43%), 13 of the 69 patients with PV (19%) and 1 of the 66 patients with ET (1.5%)--each initially without MF--developed MF regardless of myelosuppressive therapy...
  61. ncbi request reprint [Primary nursing and case management: facilitating transitions]
    Thomas Fischer
    Klinikum der Johann Wolfgang Goethe Universität Frankfurt M, Stabsstelle Pflegeforschung, Haus 57, Theodor Stern Kai 7, 60590 Frankfurt M
    Pflege Z 57:275-7. 2004
  62. ncbi request reprint Stability of radioactive colloids for radiation synovectomy: influence of X-ray contrast agents, anaesthetics and glucocorticoids in vitro
    Klaus Schomacker
    Department of Nuclear Medicine, University of Cologne, Cologne, Germany
    Nucl Med Commun 26:1027-35. 2005
    ....
  63. ncbi request reprint Sustained complete molecular remissions after treatment with imatinib-mesylate in patients with failure after allogeneic stem cell transplantation for chronic myelogenous leukemia: results of a prospective phase II open-label multicenter study
    Georg Hess
    III Med Klinik, Johannes Gutenberg University, Mainz University of Ulm, II Med Klinik, Charite, Germany
    J Clin Oncol 23:7583-93. 2005
    ....
  64. ncbi request reprint Impact of heparin management on release of tissue factor pathway inhibitor during cardiopulmonary bypass
    Thomas Fischer
    Anesthesiology 100:1040. 2004
  65. ncbi request reprint The MicroMed DeBakey VAD--part I: The pump and the blood flow
    Evgenij V Potapov
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum, Berlin, Germany
    J Extra Corpor Technol 35:274-83. 2003
    ....
  66. ncbi request reprint Localization of 131I-labelled monoclonal antibody ERIC1 in a subcutaneous xenograft model of neuroblastoma in SCID mice
    Christina Otto
    Department of Nuclear Medicine, University of Cologne, Germany
    Nucl Med Commun 27:171-8. 2006
    ..To evaluate a novel strategy of immunolocalization of human neuroblastoma by targeting the neural cell adhesion molecule (NCAM), which is over-expressed on neuroblastoma...
  67. ncbi request reprint Videodensitometry in the examination of focal breast lesions after injection of an ultrasound contrast agent
    Jens Uwe Blohmer
    Department of Senology, St Gertrauden Krankenhaus, Paretzer Str 11 12, 10713 Berlin, Germany
    Anticancer Res 26:1691-8. 2006
    ....
  68. ncbi request reprint Evaluation of late results in breast reconstruction by latissimus dorsi flap and prosthesis implantation
    Ignazio Tarantino
    Plastic, Reconstructive and Aesthetic Surgery Unit, University Hospital, Inselspital, Bern, Switzerland
    Plast Reconstr Surg 117:1387-94. 2006
    ..Short- and medium-term evaluation after this procedure is well described in the literature, but there have been no evaluations of the late course (over 10 years) published until now...
  69. ncbi request reprint Current results on the use of imatinib mesylate in patients with relapsed Philadelphia chromosome positive leukemia after allogeneic or syngeneic hematopoietic stem cell transplantation
    Andrew J Ullmann
    3rd Medical Department, Johannes Gutenberg University, Mainz, Germany
    Keio J Med 52:182-8. 2003
    ..The data suggest that earlier start of imatinib mesylate prior to hematologic relapse in minimum residual disease (MRD) positive patients is a promising treatment concept...
  70. ncbi request reprint Management of heparin resistance during cardiopulmonary bypass: the effect of five different anticoagulation strategies on hemostatic activation
    Andreas Koster
    Department of Anesthesia, Deutsches Herzzentrum Berlin, Germany
    J Cardiothorac Vasc Anesth 17:171-5. 2003
    ..However, this poses a problem in patients insensitive to heparin. The present investigation was performed to assess different strategies of managing patients with heparin resistance during CPB...
  71. ncbi request reprint Lung protection during total cardiopulmonary bypass by isolated lung perfusion: preliminary results of a novel perfusion strategy
    Hans H Sievers
    Department of Cardiac Surgery, University Hospital Luebeck, Germany
    Ann Thorac Surg 74:1167-72; discussion 1172. 2002
    ..The present pilot study was conducted to evaluate the effect of isolated short-term lung perfusion during cardiopulmonary bypass (CPB) on inflammatory response and oxygenation...
  72. ncbi request reprint A combined stage 1 and 2 repair for hypoplastic left heart syndrome: anaesthetic considerations
    Thomas Fischer
    Paediatr Anaesth 14:525-6; author reply 526-7. 2004
  73. ncbi request reprint Outcome of upper gastro-intestinal bleeding and use of ibuprofen versus paracetamol
    William J Blot
    International Epidemiology Institute, Rockville, Maryland, USA
    Pharm World Sci 26:319-23. 2004
    ..Nonsteroidal anti-inflammatory drugs (NSAIDs) are known to increase the risk of upper gastrointestinal bleeding (UGIB). Whether the severity of outcome of UGIB associated with NSAIDs differs from non-NSAID-related UGIB is less clear...