Tanja Endrass

..These findings are interpreted in terms of a deficit in schizophrenia to transfer verbal information from the right to the left hemisphere via the corpus callosum...

..The absence of a variation with error significance might indicate that OCD patients are unable to down-regulate their monitoring activity according to external requirements...

..Furthermore, it has been shown that this is only true for the late Pe, whereas the early Pe like the Ne/ERN is not modulated by error awareness...

..This is in line with fMRI results that revealed higher error- and conflict-related activity in the medial frontal cortex in OCD patients...

..Accordingly, word-related cortical networks distributed over both hemispheres allow summation of neural activity between and within hemispheres, thereby potentiating the word-related MMN...

..These data support the notion that ERN/Ne and CRN might reflect a combination of two underlying processes: an error-sensitive and an outcome-independent aspect of response monitoring...

..Results indicate that performance monitoring deficits in older adults are related to deficits in behavioral performance, at least if they are forced to respond quickly...

..This difference was absent in SZ patients, suggesting a failure to activate specific resources for incongruent S-R mappings...

..Further, this might also point to different processes reflected by Nc/CRN and Ne/ERN and to reduced error-specific monitoring but increased general or strategic monitoring in elderly...

..This finding might suggest that performance monitoring is more prone to interference by probabilistic information in older adults. Further, the salience of negative feedback seems reduced with age...

....

..The administration of time pressure seemed to force older adults to monitor error responses more specifically...

..No ERP indications of inhibitory mechanisms were found with the identity NP task. The larger P3 amplitudes in the identity priming task may indicate increased attentional resources that are necessary for the processing of NP targets...

..This might be due to weak representations of stimulus-response mappings in older adults as they learned worse. The decrease of the feedback ERN with learning and aging might suggest a decline of attention paid to negative feedback...

..The purpose of the present study was to elucidate whether overactive performance monitoring may represent a candidate endophenotype for OCD. In this case, unaffected first-degree relatives of OCD patients should also show this trait...

..In this study, it was analyzed whether patients with obsessive-compulsive disorder (OCD) show enhanced responses of their event-related brain potentials to novel stimuli, either in a context of potential threat or in a neutral context...

..Thus, the P300 carries additional information for reward processing, mainly the enhanced motivational significance of risky decisions...

..These data suggest avenues for research to examine more specific learning-related mechanisms that link anxiety to overactive error monitoring...

..The purpose of this study was to examine feedback-based learning and to investigate whether learning from positive and negative feedback is differentially altered in OCD...

..Such motor predictions are critical for inhibitory gating of actions and their consequences. Therefore, it was hypothesized that OCD patients show compromised forward model mechanisms...

..Source estimation indicates that temporal areas, particularly in the left hemisphere, are the primary cortical loci where such stimulus-specific activity increases occurred...

..The data suggest that the RCZ activity alone is insufficient to drive error awareness. Its signal appears to be useful for post-error speed-accuracy adjustments only when the error is consciously perceived...

..Our findings provide behavioural and neurophysiological evidence for reduced interhemispheric cooperation in schizophrenia which may be due to impaired transfer of information from the right to the left hemisphere...