Jan Dorr

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Can we prevent or treat multiple sclerosis by individualised vitamin D supply?
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 4:4. 2013
  2. ncbi Association of retinal and macular damage with brain atrophy in multiple sclerosis
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18132. 2011
  3. ncbi Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Trials 13:15. 2012
  4. ncbi A case of recurrent Miller Fisher syndrome mimicking botulism
    J Dorr
    HELIOS Hospital Berlin Buch, Neurology Department, Hobrechtsfelder Chaussee 96, D 13125 Berlin, Germany
    Neurol Sci 27:424-5. 2006
  5. ncbi [Susac syndrome: an interdisciplinary challenge]
    J Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Deutschland
    Nervenarzt 82:1250-63. 2011
  6. ncbi Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Charitplatz 1, 10117 Berlin, Germany
    Br J Ophthalmol 96:62-7. 2012
  7. ncbi Correlation of self-assessed fatigue and alertness in multiple sclerosis
    Nicholetta Weinges-Evers
    NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
    Mult Scler 16:1134-40. 2010
  8. ncbi Time domain and spectral domain optical coherence tomography in multiple sclerosis: a comparative cross-sectional study
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany, Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Berlin, Germany
    Mult Scler 16:893-6. 2010
  9. ncbi Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patients
    Markus Bock
    Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Neurol Neurosurg 112:647-52. 2010
  10. ncbi Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trial
    Johann Schinzel
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Trials 13:94. 2012

Collaborators

Detail Information

Publications26

  1. ncbi Can we prevent or treat multiple sclerosis by individualised vitamin D supply?
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 4:4. 2013
    ....
  2. ncbi Association of retinal and macular damage with brain atrophy in multiple sclerosis
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18132. 2011
    ..Whereas BPF best reflects disease severity, RNFLT might be the better parameter for monitoring axonal damage longitudinally. Longitudinal studies are necessary for validation of data and to further clarify the relevance of TMV...
  3. ncbi Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Trials 13:15. 2012
    ....
  4. ncbi A case of recurrent Miller Fisher syndrome mimicking botulism
    J Dorr
    HELIOS Hospital Berlin Buch, Neurology Department, Hobrechtsfelder Chaussee 96, D 13125 Berlin, Germany
    Neurol Sci 27:424-5. 2006
    ....
  5. ncbi [Susac syndrome: an interdisciplinary challenge]
    J Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Deutschland
    Nervenarzt 82:1250-63. 2011
    ..Accordingly, the focus is on the clinical presentation and the diagnostic approach...
  6. ncbi Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Charitplatz 1, 10117 Berlin, Germany
    Br J Ophthalmol 96:62-7. 2012
    ....
  7. ncbi Correlation of self-assessed fatigue and alertness in multiple sclerosis
    Nicholetta Weinges-Evers
    NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
    Mult Scler 16:1134-40. 2010
    ..Fatigue is the most common symptom in multiple sclerosis patients, but is difficult to measure; quantification thus relies on self-assessed questionnaires...
  8. ncbi Time domain and spectral domain optical coherence tomography in multiple sclerosis: a comparative cross-sectional study
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany, Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Berlin, Germany
    Mult Scler 16:893-6. 2010
    ..001). However, owing to considerable differences in absolute retinal nerve fibre layer measurements (mean +/- standard deviation 8.1 microm +/- 6.2, range -12 to 23 microm), results from the two devices are not interchangeable...
  9. ncbi Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patients
    Markus Bock
    Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Neurol Neurosurg 112:647-52. 2010
    ....
  10. ncbi Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trial
    Johann Schinzel
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Trials 13:94. 2012
    ..The aim of this pilot study is to evaluate whether residual visual deficits after past or recent optic neuritis can be reduced by means of vision restoration therapy...
  11. ncbi Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charité University Medicine and Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Arch Neurol 69:739-45. 2012
    ..Black holes are histopathologically associated with axonal loss and severe tissue destruction. In addition, double inversion recovery techniques were developed to improve the sensitivity to cortical lesions...
  12. ncbi Metabolic changes in the visual cortex are linked to retinal nerve fiber layer thinning in multiple sclerosis
    Caspar F Pfueller
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18019. 2011
    ....
  13. ncbi Characterization of natural killer cells in paired CSF and blood samples during neuroinflammation
    Isabell Hamann
    Experimental and Clinical Research Center, Charité Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany
    J Neuroimmunol 254:165-9. 2013
    ..Our findings suggest that, as for central memory T cells, CSF may represent an intermediary compartment for NK cell trafficking and differentiation before entering the CNS parenchyma...
  14. ncbi Periventricular venous density in multiple sclerosis is inversely associated with T2 lesion count: a 7 Tesla MRI study
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
    Mult Scler 19:316-25. 2013
    ..Today, ultrahigh magnetic field strength T2*-weighted magnetic resonance imaging (MRI) techniques depict very small cerebral veins in vivo with great anatomical detail...
  15. ncbi Lesion morphology at 7 Tesla MRI differentiates Susac syndrome from multiple sclerosis
    Jens Wuerfel
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Mult Scler 18:1592-9. 2012
    ....
  16. ncbi Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndrome
    Jan Dorr
    NeuroCure Clinical Research Center Charité Universitätsmedizin Berlin, Berlin, Germany
    Nat Rev Neurol 5:683-8. 2009
    ....
  17. ncbi Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS
    Alexander U Brandt
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 7:e38741. 2012
    ..These findings recommend optical coherence tomography as a promising tool for differentiating Susac syndrome from MS...
  18. ncbi Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis
    Coralie Chanvillard
    Experimental and Clinical Research Center, Charité Medical Faculty, Berlin, Germany
    PLoS ONE 7:e39625. 2012
    ..Our data emphasize the complex immunomodulatory role of mitoxantrone, which may account for its benefit in MS. In particular, these results highlight the contribution of NK cells to mitoxantrone efficacy in progressive MS...
  19. ncbi Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Neurology 79:708-14. 2012
    ..To investigate distinct white matter and cortical gray matter pathology in neuromyelitis optica spectrum disorders (NMOSDs) and multiple sclerosis (MS) at 7-T MRI in a cross-sectional study...
  20. ncbi Exercise in multiple sclerosis -- an integral component of disease management
    Andrea Döring
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    EPMA J 3:2. 2011
    ..Other treatment strategies such as drug treatments or cognitive training were deliberately excluded for the purposes of this article...
  21. ncbi Induction of TRAIL-mediated glioma cell death by human T cells
    Jan Dorr
    Division of Neuroimmunology, Department of Neurology, Charite, Neuroscientific Research Center, 10098, Berlin, Germany
    J Neuroimmunol 122:117-24. 2002
    ..Thus, TRAIL-mediated signaling is involved in T cell cytotoxicity towards glioma cell lines, which might play an important role in tumor regression...
  22. ncbi Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosis
    Jan Dorr
    Cecilie Vogt Clinic for Neurology in the HELIOS Hospital Berlin Buch, Charite Universitaetsmedizin Berlin, Germany
    Lancet Neurol 7:368-72. 2008
  23. ncbi Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy
    Nadja Borisow
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 3:9. 2012
    ..Here, we provide an overview about the current state of knowledge regarding these issues...
  24. ncbi Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis
    Friedemann Paul
    Cecilie Vogt Clinic for Neurology in the HELIOS Clinic Berlin Buch, Charité University Medicine Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany
    PLoS ONE 3:e1928. 2008
    ..Recent data from animal models of multiple sclerosis (MS) and from a pilot study indicated a possible beneficial impact of statins on MS...
  25. ncbi Attention Network Test reveals alerting network dysfunction in multiple sclerosis
    Carsten Urbanek
    Department of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany
    Mult Scler 16:93-9. 2010
    ..The Attention Network Test revealed specific alterations of the attention network in multiple sclerosis patients which were not explained by an overall cognitive slowing...
  26. ncbi Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
    Johannes Vogt
    Institute of Cell Biology and Neurobiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Ann Neurol 66:310-22. 2009
    ..Here, we investigated the role of neuronal cell loss in MS and its animal model, experimental autoimmune encephalomyelitis (EAE)...