Jan Dorr

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. pmc Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS
    Alexander U Brandt
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 7:e38741. 2012
  2. ncbi request reprint Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis
    Johann Schinzel
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    BMC Neurol 14:31. 2014
  3. pmc Trichuris suis ova in relapsing-remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial
    Berit Rosche
    Department of Neurology and Experimental Neurology, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin 10117, Germany
    Trials 14:112. 2013
  4. doi request reprint Characteristics of Susac syndrome: a review of all reported cases
    Jan Dorr
    NeuroCure Clinical Research Centre, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Rev Neurol 9:307-16. 2013
  5. pmc Can we prevent or treat multiple sclerosis by individualised vitamin D supply?
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 4:4. 2013
  6. pmc Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Trials 13:15. 2012
  7. pmc Association of retinal and macular damage with brain atrophy in multiple sclerosis
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18132. 2011
  8. doi request reprint [Susac syndrome: an interdisciplinary challenge]
    J Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Deutschland
    Nervenarzt 82:1250-63. 2011
  9. ncbi request reprint A case of recurrent Miller Fisher syndrome mimicking botulism
    J Dorr
    HELIOS Hospital Berlin Buch, Neurology Department, Hobrechtsfelder Chaussee 96, D 13125 Berlin, Germany
    Neurol Sci 27:424-5. 2006
  10. doi request reprint Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Charitplatz 1, 10117 Berlin, Germany
    Br J Ophthalmol 96:62-7. 2012

Collaborators

Detail Information

Publications32

  1. pmc Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MS
    Alexander U Brandt
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 7:e38741. 2012
    ..These findings recommend optical coherence tomography as a promising tool for differentiating Susac syndrome from MS...
  2. ncbi request reprint Relations of low contrast visual acuity, quality of life and multiple sclerosis functional composite: a cross-sectional analysis
    Johann Schinzel
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    BMC Neurol 14:31. 2014
    ..Here, we evaluate the relations between SLCLA, retinal integrity, MSFC, and quality of life (QoL) in MS patients...
  3. pmc Trichuris suis ova in relapsing-remitting multiple sclerosis and clinically isolated syndrome (TRIOMS): study protocol for a randomized controlled trial
    Berit Rosche
    Department of Neurology and Experimental Neurology, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin 10117, Germany
    Trials 14:112. 2013
    ....
  4. doi request reprint Characteristics of Susac syndrome: a review of all reported cases
    Jan Dorr
    NeuroCure Clinical Research Centre, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Nat Rev Neurol 9:307-16. 2013
    ..Where possible, we make recommendations for clinical diagnosis, differential diagnosis, and management of patients with suspected Susac syndrome...
  5. pmc Can we prevent or treat multiple sclerosis by individualised vitamin D supply?
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 4:4. 2013
    ....
  6. pmc Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Trials 13:15. 2012
    ....
  7. pmc Association of retinal and macular damage with brain atrophy in multiple sclerosis
    Jan Dorr
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18132. 2011
    ..Whereas BPF best reflects disease severity, RNFLT might be the better parameter for monitoring axonal damage longitudinally. Longitudinal studies are necessary for validation of data and to further clarify the relevance of TMV...
  8. doi request reprint [Susac syndrome: an interdisciplinary challenge]
    J Dorr
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Deutschland
    Nervenarzt 82:1250-63. 2011
    ..Accordingly, the focus is on the clinical presentation and the diagnostic approach...
  9. ncbi request reprint A case of recurrent Miller Fisher syndrome mimicking botulism
    J Dorr
    HELIOS Hospital Berlin Buch, Neurology Department, Hobrechtsfelder Chaussee 96, D 13125 Berlin, Germany
    Neurol Sci 27:424-5. 2006
    ....
  10. doi request reprint Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosis
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Charitplatz 1, 10117 Berlin, Germany
    Br J Ophthalmol 96:62-7. 2012
    ....
  11. doi request reprint Correlation of self-assessed fatigue and alertness in multiple sclerosis
    Nicholetta Weinges-Evers
    NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
    Mult Scler 16:1134-40. 2010
    ..Fatigue is the most common symptom in multiple sclerosis patients, but is difficult to measure; quantification thus relies on self-assessed questionnaires...
  12. doi request reprint Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patients
    Markus Bock
    Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Neurol Neurosurg 112:647-52. 2010
    ....
  13. doi request reprint Time domain and spectral domain optical coherence tomography in multiple sclerosis: a comparative cross-sectional study
    Markus Bock
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany, Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Berlin, Germany
    Mult Scler 16:893-6. 2010
    ..001). However, owing to considerable differences in absolute retinal nerve fibre layer measurements (mean +/- standard deviation 8.1 microm +/- 6.2, range -12 to 23 microm), results from the two devices are not interchangeable...
  14. pmc Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trial
    Johann Schinzel
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Trials 13:94. 2012
    ..The aim of this pilot study is to evaluate whether residual visual deficits after past or recent optic neuritis can be reduced by means of vision restoration therapy...
  15. pmc Metabolic changes in the visual cortex are linked to retinal nerve fiber layer thinning in multiple sclerosis
    Caspar F Pfueller
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    PLoS ONE 6:e18019. 2011
    ....
  16. doi request reprint Periventricular venous density in multiple sclerosis is inversely associated with T2 lesion count: a 7 Tesla MRI study
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
    Mult Scler 19:316-25. 2013
    ..Today, ultrahigh magnetic field strength T2*-weighted magnetic resonance imaging (MRI) techniques depict very small cerebral veins in vivo with great anatomical detail...
  17. doi request reprint Optic neuritis interferes with optical coherence tomography and magnetic resonance imaging correlations
    Hanna Zimmermann
    NeuroCure Clinical Research Centre and Experimental and Clinical Research Centre, Charité Universitätsmedizin Berlin and Max Delbrueck Centre for Molecular Medicine, Berlin, Germany
    Mult Scler 19:443-50. 2013
    ..Recently, the retinal ganglion cell layer (GCL) has been shown to provide superior information regarding visual function and retinal neurodegeneration as compared with RNFL...
  18. doi request reprint Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging study
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charité University Medicine and Max Delbruck Center for Molecular Medicine, Berlin, Germany
    Arch Neurol 69:739-45. 2012
    ..Black holes are histopathologically associated with axonal loss and severe tissue destruction. In addition, double inversion recovery techniques were developed to improve the sensitivity to cortical lesions...
  19. doi request reprint Lesion morphology at 7 Tesla MRI differentiates Susac syndrome from multiple sclerosis
    Jens Wuerfel
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Mult Scler 18:1592-9. 2012
    ....
  20. doi request reprint Characterization of natural killer cells in paired CSF and blood samples during neuroinflammation
    Isabell Hamann
    Experimental and Clinical Research Center, Charité Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany
    J Neuroimmunol 254:165-9. 2013
    ..Our findings suggest that, as for central memory T cells, CSF may represent an intermediary compartment for NK cell trafficking and differentiation before entering the CNS parenchyma...
  21. ncbi request reprint Effects of deep repetitive transcranial magnetic stimulation on brain-derived neurotrophic factor serum concentration in healthy volunteers
    Gunnar Gaede
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
    Neuropsychobiology 69:112-9. 2014
    ..We aimed to evaluate the short-term effect of deep rTMS on BDNF serum concentrations...
  22. doi request reprint Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosis
    Tim Sinnecker
    NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Neurology 79:708-14. 2012
    ..To investigate distinct white matter and cortical gray matter pathology in neuromyelitis optica spectrum disorders (NMOSDs) and multiple sclerosis (MS) at 7-T MRI in a cross-sectional study...
  23. doi request reprint Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndrome
    Jan Dorr
    NeuroCure Clinical Research Center Charité Universitätsmedizin Berlin, Berlin, Germany
    Nat Rev Neurol 5:683-8. 2009
    ....
  24. pmc Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosis
    Friedemann Paul
    Cecilie Vogt Clinic for Neurology in the HELIOS Clinic Berlin Buch, Charité University Medicine Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany
    PLoS ONE 3:e1928. 2008
    ..Recent data from animal models of multiple sclerosis (MS) and from a pilot study indicated a possible beneficial impact of statins on MS...
  25. pmc Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosis
    Coralie Chanvillard
    Experimental and Clinical Research Center, Charité Medical Faculty, Berlin, Germany
    PLoS ONE 7:e39625. 2012
    ..Our data emphasize the complex immunomodulatory role of mitoxantrone, which may account for its benefit in MS. In particular, these results highlight the contribution of NK cells to mitoxantrone efficacy in progressive MS...
  26. ncbi request reprint Pregnancy in multiple sclerosis: a questionnaire study
    Nadja Borisow
    NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany Clinical and Experimental Multiple Sclerosis Research Center, Department of Neurology, Charite Universitatsmedizin Berlin, Berlin, Germany
    PLoS ONE 9:e99106. 2014
    ..Multiple sclerosis (MS) preferentially affects females at childbearing age. For this reason patients and treating physicians were frequently confronted with questions concerning family planning, pregnancy and birth...
  27. doi request reprint Attention Network Test reveals alerting network dysfunction in multiple sclerosis
    Carsten Urbanek
    Department of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany
    Mult Scler 16:93-9. 2010
    ..The Attention Network Test revealed specific alterations of the attention network in multiple sclerosis patients which were not explained by an overall cognitive slowing...
  28. pmc Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancy
    Nadja Borisow
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
    EPMA J 3:9. 2012
    ..Here, we provide an overview about the current state of knowledge regarding these issues...
  29. doi request reprint Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitis
    Johannes Vogt
    Institute of Cell Biology and Neurobiology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Ann Neurol 66:310-22. 2009
    ..Here, we investigated the role of neuronal cell loss in MS and its animal model, experimental autoimmune encephalomyelitis (EAE)...
  30. pmc Exercise in multiple sclerosis -- an integral component of disease management
    Andrea Döring
    NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    EPMA J 3:2. 2011
    ..Other treatment strategies such as drug treatments or cognitive training were deliberately excluded for the purposes of this article...
  31. ncbi request reprint Induction of TRAIL-mediated glioma cell death by human T cells
    Jan Dorr
    Division of Neuroimmunology, Department of Neurology, Charite, Neuroscientific Research Center, 10098, Berlin, Germany
    J Neuroimmunol 122:117-24. 2002
    ..Thus, TRAIL-mediated signaling is involved in T cell cytotoxicity towards glioma cell lines, which might play an important role in tumor regression...
  32. doi request reprint Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosis
    Jan Dorr
    Cecilie Vogt Clinic for Neurology in the HELIOS Hospital Berlin Buch, Charite Universitaetsmedizin Berlin, Germany
    Lancet Neurol 7:368-72. 2008