Research Topics
| Jan DorrSummaryAffiliation: Humboldt University Country: Germany Publications
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Detail Information
Publications
Can we prevent or treat multiple sclerosis by individualised vitamin D supply?Jan Dorr
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
EPMA J 4:4. 2013....
Association of retinal and macular damage with brain atrophy in multiple sclerosisJan Dorr
NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
PLoS ONE 6:e18132. 2011..Whereas BPF best reflects disease severity, RNFLT might be the better parameter for monitoring axonal damage longitudinally. Longitudinal studies are necessary for validation of data and to further clarify the relevance of TMV...
Efficacy of vitamin D supplementation in multiple sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trialJan Dorr
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
Trials 13:15. 2012....
A case of recurrent Miller Fisher syndrome mimicking botulismJ Dorr
HELIOS Hospital Berlin Buch, Neurology Department, Hobrechtsfelder Chaussee 96, D 13125 Berlin, Germany
Neurol Sci 27:424-5. 2006....
[Susac syndrome: an interdisciplinary challenge]J Dorr
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Deutschland
Nervenarzt 82:1250-63. 2011..Accordingly, the focus is on the clinical presentation and the diagnostic approach...
Impairment of contrast visual acuity as a functional correlate of retinal nerve fibre layer thinning and total macular volume reduction in multiple sclerosisMarkus Bock
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Charitplatz 1, 10117 Berlin, Germany
Br J Ophthalmol 96:62-7. 2012....
Correlation of self-assessed fatigue and alertness in multiple sclerosisNicholetta Weinges-Evers
NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
Mult Scler 16:1134-40. 2010..Fatigue is the most common symptom in multiple sclerosis patients, but is difficult to measure; quantification thus relies on self-assessed questionnaires...
Time domain and spectral domain optical coherence tomography in multiple sclerosis: a comparative cross-sectional studyMarkus Bock
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany, Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Berlin, Germany
Mult Scler 16:893-6. 2010..001). However, owing to considerable differences in absolute retinal nerve fibre layer measurements (mean +/- standard deviation 8.1 microm +/- 6.2, range -12 to 23 microm), results from the two devices are not interchangeable...
Patterns of retinal nerve fiber layer loss in multiple sclerosis patients with or without optic neuritis and glaucoma patientsMarkus Bock
Cecilie Vogt Clinic, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
Clin Neurol Neurosurg 112:647-52. 2010....
Efficacy of vision restoration therapy after optic neuritis (VISION study): study protocol for a randomized controlled trialJohann Schinzel
NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
Trials 13:94. 2012..The aim of this pilot study is to evaluate whether residual visual deficits after past or recent optic neuritis can be reduced by means of vision restoration therapy...
Multiple sclerosis lesions and irreversible brain tissue damage: a comparative ultrahigh-field strength magnetic resonance imaging studyTim Sinnecker
NeuroCure Clinical Research Center, Charité University Medicine and Max Delbruck Center for Molecular Medicine, Berlin, Germany
Arch Neurol 69:739-45. 2012..Black holes are histopathologically associated with axonal loss and severe tissue destruction. In addition, double inversion recovery techniques were developed to improve the sensitivity to cortical lesions...
Metabolic changes in the visual cortex are linked to retinal nerve fiber layer thinning in multiple sclerosisCaspar F Pfueller
NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
PLoS ONE 6:e18019. 2011....
Characterization of natural killer cells in paired CSF and blood samples during neuroinflammationIsabell Hamann
Experimental and Clinical Research Center, Charité Universitätsmedizin Berlin and Max Delbrück Center for Molecular Medicine, Berlin, Germany
J Neuroimmunol 254:165-9. 2013..Our findings suggest that, as for central memory T cells, CSF may represent an intermediary compartment for NK cell trafficking and differentiation before entering the CNS parenchyma...
Periventricular venous density in multiple sclerosis is inversely associated with T2 lesion count: a 7 Tesla MRI studyTim Sinnecker
NeuroCure Clinical Research Center, Charite University Medicine Berlin, Germany
Mult Scler 19:316-25. 2013..Today, ultrahigh magnetic field strength T2*-weighted magnetic resonance imaging (MRI) techniques depict very small cerebral veins in vivo with great anatomical detail...
Lesion morphology at 7 Tesla MRI differentiates Susac syndrome from multiple sclerosisJens Wuerfel
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
Mult Scler 18:1592-9. 2012....
Encephalopathy, visual disturbance and hearing loss-recognizing the symptoms of Susac syndromeJan Dorr
NeuroCure Clinical Research Center Charité Universitätsmedizin Berlin, Berlin, Germany
Nat Rev Neurol 5:683-8. 2009....
Patterns of retinal damage facilitate differential diagnosis between Susac syndrome and MSAlexander U Brandt
NeuroCure Clinical Research Center, Charite Universitatsmedizin Berlin, Berlin, Germany
PLoS ONE 7:e38741. 2012..These findings recommend optical coherence tomography as a promising tool for differentiating Susac syndrome from MS...
Mitoxantrone induces natural killer cell maturation in patients with secondary progressive multiple sclerosisCoralie Chanvillard
Experimental and Clinical Research Center, Charité Medical Faculty, Berlin, Germany
PLoS ONE 7:e39625. 2012..Our data emphasize the complex immunomodulatory role of mitoxantrone, which may account for its benefit in MS. In particular, these results highlight the contribution of NK cells to mitoxantrone efficacy in progressive MS...
Distinct lesion morphology at 7-T MRI differentiates neuromyelitis optica from multiple sclerosisTim Sinnecker
NeuroCure Clinical Research Center, Charite Universitaetsmedizin Berlin, Berlin, Germany
Neurology 79:708-14. 2012..To investigate distinct white matter and cortical gray matter pathology in neuromyelitis optica spectrum disorders (NMOSDs) and multiple sclerosis (MS) at 7-T MRI in a cross-sectional study...
Exercise in multiple sclerosis -- an integral component of disease managementAndrea Döring
NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
EPMA J 3:2. 2011..Other treatment strategies such as drug treatments or cognitive training were deliberately excluded for the purposes of this article...
Induction of TRAIL-mediated glioma cell death by human T cellsJan Dorr
Division of Neuroimmunology, Department of Neurology, Charite, Neuroscientific Research Center, 10098, Berlin, Germany
J Neuroimmunol 122:117-24. 2002..Thus, TRAIL-mediated signaling is involved in T cell cytotoxicity towards glioma cell lines, which might play an important role in tumor regression...
Treatment-resistant chronic headaches and focal pachymeningitis in a 46-year-old man: a rare presentation of Wegener's granulomatosisJan Dorr
Cecilie Vogt Clinic for Neurology in the HELIOS Hospital Berlin Buch, Charite Universitaetsmedizin Berlin, Germany
Lancet Neurol 7:368-72. 2008
Expert recommendations to personalization of medical approaches in treatment of multiple sclerosis: an overview of family planning and pregnancyNadja Borisow
NeuroCure Clinical Research Center and Clinical and Experimental Research Center for Multiple Sclerosis, Charite Universitatsmedizin Berlin, Chariteplatz 1, Berlin, 10117, Germany
EPMA J 3:9. 2012..Here, we provide an overview about the current state of knowledge regarding these issues...
Oral high-dose atorvastatin treatment in relapsing-remitting multiple sclerosisFriedemann Paul
Cecilie Vogt Clinic for Neurology in the HELIOS Clinic Berlin Buch, Charité University Medicine Berlin and Max Delbrueck Center for Molecular Medicine, Berlin, Germany
PLoS ONE 3:e1928. 2008..Recent data from animal models of multiple sclerosis (MS) and from a pilot study indicated a possible beneficial impact of statins on MS...
Attention Network Test reveals alerting network dysfunction in multiple sclerosisCarsten Urbanek
Department of Psychiatry and Psychotherapy, Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany
Mult Scler 16:93-9. 2010..The Attention Network Test revealed specific alterations of the attention network in multiple sclerosis patients which were not explained by an overall cognitive slowing...
Lower motor neuron loss in multiple sclerosis and experimental autoimmune encephalomyelitisJohannes Vogt
Institute of Cell Biology and Neurobiology, Charite Universitatsmedizin Berlin, Berlin, Germany
Ann Neurol 66:310-22. 2009..Here, we investigated the role of neuronal cell loss in MS and its animal model, experimental autoimmune encephalomyelitis (EAE)...
