Maria Deja

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Strategies for diagnosis and treatment of iatrogenic tracheal ruptures
    M Deja
    Department of Anesthesiology and Intensive Care Medicine, Charite, Berlin Medical University, Campus Virchow Klinikum, Campus Charite Mitte, Berlin, Germany
    Minerva Anestesiol 77:1155-66. 2011
  2. ncbi request reprint Goal-directed therapy of cardiac preload in induced whole-body hyperthermia
    Maria Deja
    Department of Anesthesiology and Critical Care Medicine, Charite Medical Center, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
    Chest 128:580-6. 2005
  3. pmc Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome
    Maria Deja
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Crit Care 10:R147. 2006
  4. ncbi request reprint [Strategies in the treatment of infections with antibiotics in intensive care medicine]
    Maria Deja
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum
    Anasthesiol Intensivmed Notfallmed Schmerzther 42:108-15. 2007
  5. ncbi request reprint Evidence-based therapy of severe acute respiratory distress syndrome: an algorithm-guided approach
    M Deja
    Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    J Int Med Res 36:211-21. 2008
  6. doi request reprint [Epidemiology and Pathophysiology of the acute respiratory distress syndrome (ARDS)]
    Maria Deja
    Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 43:758-66; quiz 768. 2008
  7. doi request reprint Changes in hepatic blood flow during whole body hyperthermia
    Maria Deja
    Department of Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Germany
    Int J Hyperthermia 26:95-100. 2010
  8. doi request reprint Critical illness myopathy is frequent: accompanying neuropathy protracts ICU discharge
    Susanne Koch
    Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Augustenburger Platz 1, Berlin D 13353, Germany
    J Neurol Neurosurg Psychiatry 82:287-93. 2011
  9. ncbi request reprint Endothelin-1 influences the efficacy of inhaled nitric oxide in experimental acute lung injury
    Thilo Busch
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, University Medical Center, Berlin, Germany
    Exp Biol Med (Maywood) 231:974-8. 2006
  10. doi request reprint Inhalation of an endothelin receptor A antagonist attenuates pulmonary inflammation in experimental acute lung injury
    Philipp Kalk
    Center for Cardiovascular Research, Department of Pharmacology and Toxicology, Charite, Campus Mitte, Hessische Str 3 4, Berlin, Germany
    Can J Physiol Pharmacol 86:511-5. 2008

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Strategies for diagnosis and treatment of iatrogenic tracheal ruptures
    M Deja
    Department of Anesthesiology and Intensive Care Medicine, Charite, Berlin Medical University, Campus Virchow Klinikum, Campus Charite Mitte, Berlin, Germany
    Minerva Anestesiol 77:1155-66. 2011
    ..Our aim was to comprise a structured diagnostic and treatment protocol for patients suspicious of tracheal injury, including detailed principles of mechanical ventilation and specific indications for conservative or surgical treatment...
  2. ncbi request reprint Goal-directed therapy of cardiac preload in induced whole-body hyperthermia
    Maria Deja
    Department of Anesthesiology and Critical Care Medicine, Charite Medical Center, Campus Virchow Clinic, Augustenburger Platz 1, 13353 Berlin, Germany
    Chest 128:580-6. 2005
    ..To optimize volume therapy during induced whole-body hyperthermia (WBH) < or = 42.2 degrees C, pulmonary capillary wedge pressure (PCWP) and intrathoracic blood volume index (ITBVI) were compared as goal parameters...
  3. pmc Social support during intensive care unit stay might improve mental impairment and consequently health-related quality of life in survivors of severe acute respiratory distress syndrome
    Maria Deja
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
    Crit Care 10:R147. 2006
    ..We wished to evaluate the influence of PTSD on HRQoL and to investigate the influence of perceived social support during intensive care unit (ICU) treatment on both PTSD symptoms and HRQoL...
  4. ncbi request reprint [Strategies in the treatment of infections with antibiotics in intensive care medicine]
    Maria Deja
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum
    Anasthesiol Intensivmed Notfallmed Schmerzther 42:108-15. 2007
    ..The aim of this educational article is to portray a selection of the pre-requisites and strategies available in the treatment of infections with antibiotics in intensive care medicine...
  5. ncbi request reprint Evidence-based therapy of severe acute respiratory distress syndrome: an algorithm-guided approach
    M Deja
    Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    J Int Med Res 36:211-21. 2008
    ..This review summarizes the current evidence base and proposes a new treatment algorithm that aims to prioritize the administration of advanced strategies in a multimodal approach for ARDS...
  6. doi request reprint [Epidemiology and Pathophysiology of the acute respiratory distress syndrome (ARDS)]
    Maria Deja
    Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin
    Anasthesiol Intensivmed Notfallmed Schmerzther 43:758-66; quiz 768. 2008
    ..Furthermore, we try to elucidate possible reasons for considerable limitations of multicentric studies in this field...
  7. doi request reprint Changes in hepatic blood flow during whole body hyperthermia
    Maria Deja
    Department of Anaesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Germany
    Int J Hyperthermia 26:95-100. 2010
    ..The aim of this clinical study was to determine changes in hepatic blood flow during WBH for the treatment of metastatic cancer...
  8. doi request reprint Critical illness myopathy is frequent: accompanying neuropathy protracts ICU discharge
    Susanne Koch
    Department of Anesthesiology and Intensive Care Medicine, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum and Campus Mitte, Augustenburger Platz 1, Berlin D 13353, Germany
    J Neurol Neurosurg Psychiatry 82:287-93. 2011
    ..However, it is unknown whether differential diagnosis has an impact on prognosis. This study investigates whether there is an association between the early differentiation of CIM versus CIP and clinical prognosis...
  9. ncbi request reprint Endothelin-1 influences the efficacy of inhaled nitric oxide in experimental acute lung injury
    Thilo Busch
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, University Medical Center, Berlin, Germany
    Exp Biol Med (Maywood) 231:974-8. 2006
    ..548, P = 0.001). Our data suggest that endogenous ET-1 production influences the efficacy of iNO in ALI. Furthermore, iNO reduced ET-1 plasma levels, possibly indicating anti-inflammatory properties of iNO in the early phase of ALI...
  10. doi request reprint Inhalation of an endothelin receptor A antagonist attenuates pulmonary inflammation in experimental acute lung injury
    Philipp Kalk
    Center for Cardiovascular Research, Department of Pharmacology and Toxicology, Charite, Campus Mitte, Hessische Str 3 4, Berlin, Germany
    Can J Physiol Pharmacol 86:511-5. 2008
    ..In conclusion, we demonstrated that inhalation of LU 135252 not only improves mortality and gas exchange, but also blunts the local immune response in experimental ALI...
  11. ncbi request reprint Low-dose inhalation of an endothelin-A receptor antagonist in experimental acute lung injury: ET-1 plasma concentration and pulmonary inflammation
    Bernd Donaubauer
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, University Medical Center, Berlin, Germany
    Exp Biol Med (Maywood) 231:960-6. 2006
    ..Furthermore, our data indicate a trend toward decreased pulmonary inflammation in the group receiving the inhaled ET(A) receptor antagonist...
  12. ncbi request reprint Inhalation of the endothelin-A receptor antagonist LU-135252 at various doses in experimental acute lung injury
    Maria Deja
    Department of Anesthesiology and Intensive Care Medicine, University Medical Center, Berlin, Germany
    J Cardiovasc Pharmacol 44:S151-5. 2004
    ....
  13. pmc Risk factors in critical illness myopathy during the early course of critical illness: a prospective observational study
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite University Medicine, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany
    Crit Care 14:R119. 2010
    ..Non-excitable muscle membrane indicates critical illness myopathy (CIM) during early critical illness. We investigated predisposing risk factors for non-excitable muscle membrane at onset of critical illness...
  14. doi request reprint Impact of adherence to standard operating procedures for pneumonia on outcome of intensive care unit patients
    Irit Nachtigall
    Charite Universitaetsmedizin Berlin, Department of Anesthesiology and Intensive Care, Campus Charite Mitte, Germany
    Crit Care Med 37:159-66. 2009
    ..Pneumonia accounts for almost half of intensive care unit (ICU) infections and nearly 60% of deaths from nosocomial infections. It increases hospital stay by 7-9 days, crude mortality by 70% and attributable mortality by 30%...
  15. ncbi request reprint Stress induced changes in lymphocyte subpopulations and associated cytokines during whole body hyperthermia of 41.8-42.2 degrees C
    Olaf Ahlers
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum, 13344, Berlin, Germany
    Eur J Appl Physiol 95:298-306. 2005
    ..Further studies are necessary to examine the pathophysiological details and to evaluate the meaning of these transient immunological changes for patient's outcome...
  16. ncbi request reprint Critical illness polyneuropathy and myopathy in patients with acute respiratory distress syndrome
    Sven Bercker
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, University Medical Center, Berlin, Germany
    Crit Care Med 33:711-5. 2005
    ..Clinically relevant paresis is major symptom of CIP/CIM. We aimed at determining risk factors and diagnostic value of electrophysiologic testing for CIP/CIM in patients with acute respiratory distress syndrome (ARDS)...
  17. doi request reprint Hypercapnia in late-phase ALI/ARDS: providing spontaneous breathing using pumpless extracorporeal lung assist
    Steffen Weber-Carstens
    Department of Anesthesiology and Intensive Care Medicine, Charite, Universitatsmedizin Berlin, Campus Virchow Klinikum, Campus Mitte, Berlin, Germany
    Intensive Care Med 35:1100-5. 2009
    ....
  18. ncbi request reprint Impact of bolus application of low-dose hydrocortisone on glycemic control in septic shock patients
    Steffen Weber-Carstens
    Clinic of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum and Campus Mitte, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Intensive Care Med 33:730-3. 2007
    ..To determine whether glycemic control is less feasible when hydrocortisone is given as a bolus compared with continuous application in septic shock patients...
  19. ncbi request reprint Selective pulmonary vasodilation in acute respiratory distress syndrome
    Udo Kaisers
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, Humboldt University Berlin, Berlin, Germany
    Crit Care Med 31:S337-42. 2003
    ..Cost-benefit analysis of these therapeutic options will largely determine their future perspective...
  20. ncbi request reprint [Implementation of standard operating procedures for the initial empirical antimicrobial therapy for adults--a new computer program at the University Hospital Charité]
    Irit Nachtigall
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Charite Universitatsmedizin Berlin, Campus Virchow Klinikum und Campus Charité Mitte
    Anasthesiol Intensivmed Notfallmed Schmerzther 41:626-35. 2006
    ..The authors developed algorithms and generated a user friendly computer program available for all ICU physicians all the time...
  21. ncbi request reprint [Standards, guidelines and recommendations for antibiotic therapy]
    Claudia D Spies
    Kliniken für Anästhesiologie und operative Intensivmedizin, Universitatsmedizin Berlin, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 42:106-7. 2007
  22. doi request reprint Nonexcitable muscle membrane predicts intensive care unit-acquired paresis in mechanically ventilated, sedated patients
    Steffen Weber-Carstens
    Department of Anesthesiology and Intensive Care Medicine SW C, SK, CDS, FB, MD, Campus Virchow Klinikum and Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Crit Care Med 37:2632-7. 2009
    ..To investigate the predictive value of electrophysiological measurements including validation of muscle membrane excitability on the development of intensive care unit (ICU)-aquired paresis...
  23. ncbi request reprint The inhaled ET(A) receptor antagonist LU-135252 acts as a selective pulmonary vasodilator
    Maria Deja
    Klinik für Anaesthesiologie und Operative Intensivmedizin Charité, Campus Virchow Klinikum, Medizinische Fakultät der Humboldt Universitaet, Augustenburger Platz 1, D 13353 Berlin, Germany
    Clin Sci (Lond) 103:21S-24S. 2002
    ..Our results indicate the occurrence of selective pulmonary vasodilation in both treatment groups...
  24. ncbi request reprint Anaesthesiological experiences with whole body hyperthermia
    T Kerner
    Department of Anaesthesiology and Critical Care Medicine, Charite Medical Center, Virchow Hospital, Humboldt University, D 13344 Berlin, Germany
    Int J Hyperthermia 19:1-12. 2003
    ....
  25. ncbi request reprint Monitoring arterial blood pressure during whole body hyperthermia
    T Kerner
    Department of Anesthesiology and Critical Care Medicine, Charite Medical Center, Virchow Hospital, Humboldt University, Berlin
    Acta Anaesthesiol Scand 46:561-6. 2002
    ..This investigation was performed to evaluate the agreement of invasive measurements at various sites, and to compare invasive and non-invasive methods of ABP monitoring under conditions of a heat-induced extreme vasodilation...
  26. ncbi request reprint Whole-body hyperthermia in the scope of von Ardenne's systemic cancer multistep therapy (sCMT) combined with chemotherapy in patients with metastatic colorectal cancer: a phase I/II study
    B Hildebrandt
    Medizinische Klinik für Hämatologie und Onkologie, Universitätklinikum Charité, Berlin, Germany
    Int J Hyperthermia 20:317-33. 2004
    ..The fact that three patients who did not respond to initial chemotherapy achieved a PR after additional sCMT suggests that sCMT may enhance the effect of chemotherapy in patients with colorectal cancer...
  27. ncbi request reprint [Multiorgan failure due to chronic granulomatous disease]
    A Rüggeberg
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitatsklinikum Charite, Campus Virchow Klinikum Berlin, Germany
    Anaesthesist 51:731-4. 2002
    ..This case report describes the typical problems of patients with a congenital immunodeficiency who grow out of the care of highly specialised pediatric-immunological departments...
  28. ncbi request reprint Feasibility and analysis of thermal parameters for the whole-body-hyperthermia system IRATHERM-2000
    P Wust
    Department of Radiation Medicine, Charite Medical Center, Berlin, Germany
    Int J Hyperthermia 16:325-39. 2000
    ..In the authors' opinion, improved understanding of the mechanisms and crucial parameters underlying whole body hyperthermia, will enable a controllable and tolerable therapy through proficient contribution to equipment and methods...
  29. doi request reprint Experimental high-volume hemofiltration with predilutional tris-hydroxymethylaminomethane for correction of low tidal volume ventilation-induced acidosis
    Martin Russ
    Department of Experimental Medicine FEM, Charite Universitatsmedizin Berlin, Campus Virchow, Germany
    Artif Organs 35:E108-18. 2011
    ..In conclusion, predilutional THAM-application and HVHF corrected the acid-base disorder and improved pulmonary hemodynamics. Further studies are necessary to optimize the protocol including the dosage...
  30. ncbi request reprint Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis
    Maria Deja
    Department of Anesthesiology and Intemsive Care Medicine, Charite Campus Virchow Klinikum, Berlin, Germany
    Am J Respir Crit Care Med 168:281-6. 2003
    ....
  31. doi request reprint Regional hyperthermia of the abdomen in conjunction with chemotherapy for peritoneal carcinomatosis: evaluation of two annular-phased-array applicators
    C H Cho
    Charite Universitatsmedizin Berlin, Clinic for Radiotherapy, Berlin, Germany
    Int J Hyperthermia 24:399-408. 2008
    ..In this phase I/II study, we evaluated regional hyperthermia of the pelvis and abdomen using the annular-phased-array technique as an adjunct to chemotherapy...
  32. doi request reprint Computed tomography findings from patients with ARDS due to Influenza A (H1N1) virus-associated pneumonia
    Christian Grieser
    Klinik fur Strahlenheilkunde, Campus Virchow Klinikum, Charite Universitatsmedizin Berlin, Germany
    Eur J Radiol 81:389-94. 2012
    ....
  33. ncbi request reprint Gastrointestinal zygomycosis caused by Mucor indicus in a patient with acute traumatic brain injury
    Maria Deja
    Department of Anesthesiology and Intensive Care Medicine, Charite, Campus Virchow Klinikum, Universitatsmedizin, Berlin, Germany
    Med Mycol 44:683-7. 2006
    ..Reviewing other reports on Mucor indicus infections, primary gastrointestinal manifestations seem to be typical and indicate an oral route of infection...
  34. ncbi request reprint Small dose of exogenous surfactant combined with partial liquid ventilation in experimental acute lung injury: effects on gas exchange, haemodynamics, lung mechanics, and lung pathology
    S Wolf
    , , Medizinische Fakultaet der Humboldt-Universitaet, Berlin, Germany
    Br J Anaesth 87:593-601. 2001
    ....
  35. ncbi request reprint [Computed tomographic criteria as expected effect to inhaled nitric oxide in patients with severe acute respiratory distress syndrome]
    R Röttgen
    Klinik fur Strahlenheilkunde, Charite, Campus Virchow Klinikum, Universitatsmedizin Berlin, Berlin
    Rofo 177:805-11. 2005
    ..For unknown reason, a subset of ARDS patients does not respond favorably to iNO therapy. We hypothesized that radiological manifestation of lung injury may be related to iNO response...
  36. ncbi request reprint "Ideal PEEP" is superior to high dose partial liquid ventilation with low PEEP in experimental acute lung injury
    S Wolf
    Department of Anaesthesiology and Intensive Care Medicine, , Germany
    Intensive Care Med 27:1937-48. 2001
    ..In terms of lung damage, the treatment in the (ideal) PEEP group resulted in the lowest total lung injury scores...
  37. doi request reprint Bronchial fistulae in ARDS patients: management with an extracorporeal lung assist device
    M Hommel
    Dept of Anesthesiology and Intensive Care Medicine, Campus Virchow Klinikum and Campus Mitte, Berlin, Germany
    Eur Respir J 32:1652-5. 2008
    ..Initiation of a pumpless extracorporeal lung assist device enabled a less invasive ventilator management, which may have contributed to healing of surgical bronchial repair...
  38. ncbi request reprint [An appendix on the strategies for the prescription of antibiotics in intensive care: standards for microbiological diagnostics]
    Maria Deja
    Anasthesiol Intensivmed Notfallmed Schmerzther 42:108-10. 2007
  39. ncbi request reprint Inhalation of the ETA receptor antagonist LU-135252 selectively attenuates hypoxic pulmonary vasoconstriction
    Bodil Petersen
    Klinik und Poliklinik fuer Anaesthesiologie und Intensivtherapie, Universitaetsklinikum Leipzig, Liebigstrasse 20, Leipzig, Germany
    Am J Physiol Regul Integr Comp Physiol 294:R601-5. 2008
    ..Consequently, in our experimental model of HPV, the inhaled ET(A) receptor antagonist LU-135252 induced selective pulmonary vasodilation without adverse systemic hemodynamic effects...
  40. ncbi request reprint Inhaled nitric oxide in acute lung injury
    Udo Kaisers
    JAMA 292:327; author reply 327-8. 2004
  41. ncbi request reprint Pumpless extracorporeal lung assist in patients with acute respiratory distress syndrome
    Sven Bercker
    Crit Care Med 35:326; author reply 326. 2007