Maxim E Darvin

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Optical methods for noninvasive determination of carotenoids in human and animal skin
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous Physiology CCP, Chariteplatz 1, 10117 Berlin, Germany
    J Biomed Opt 18:61230. 2013
  2. doi request reprint Safety assessment by multiphoton fluorescence/second harmonic generation/hyper-Rayleigh scattering tomography of ZnO nanoparticles used in cosmetic products
    M E Darvin
    Center of Experimental and Cutaneous Physiology CCP, Department of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 25:219-26. 2012
  3. doi request reprint Comparison of two methods for noninvasive determination of carotenoids in human and animal skin: Raman spectroscopy versus reflection spectroscopy
    Maxim E Darvin
    Department of Dermatology, Venerology and Allergology, Center of Experimental and Cutaneous Physiology CCP, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Biophotonics 5:550-8. 2012
  4. ncbi request reprint Analyses of the correlation between dermal and blood carotenoids in female cattle by optical methods
    Julia Klein
    Freie Universitat Berlin, Faculty of Veterinary Medicine, Clinic for Ruminants and Swine, Berlin, Germany
    J Biomed Opt 18:061219. 2013
  5. doi request reprint Dermal carotenoid level and kinetics after topical and systemic administration of antioxidants: enrichment strategies in a controlled in vivo study
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Berlin, Germany
    J Dermatol Sci 64:53-8. 2011
  6. doi request reprint Kinetics of carotenoid distribution in human skin in vivo after exogenous stress: disinfectant and wIRA-induced carotenoid depletion recovers from outside to inside
    Joachim W Fluhr
    Charité Universitätsmedizin, Center of Experimental Applied Cutaneous Physiology, Department of Dermatology and Allergology, Berlin, Germany
    J Biomed Opt 16:035002. 2011
  7. doi request reprint Topical beta-carotene protects against infra-red-light-induced free radicals
    Maxim E Darvin
    Center of Applied Cutaneous Physiology, Department of Dermatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Exp Dermatol 20:125-9. 2011
  8. doi request reprint Raman spectroscopic analysis of the carotenoid concentration in egg yolks depending on the feeding and housing conditions of the laying hens
    Karoline Hesterberg
    Charite University Hospital Berlin, Department of Dermatology and Allergology, Center of Experimental and Cutaneous Physiology CCP, Berlin, Germany
    J Biophotonics 5:33-9. 2012
  9. doi request reprint In vivo skin treatment with tissue-tolerable plasma influences skin physiology and antioxidant profile in human stratum corneum
    Joachim W Fluhr
    Universitätsmedizin Charité, Berlin, Department of Dermatology and Allergology, Center of Experimental and Cutaneous Physiology, Berlin, Germany
    Exp Dermatol 21:130-4. 2012
  10. doi request reprint One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Chariteplatz 1, 10117 Berlin, Germany
    J Biomed Opt 13:044028. 2008

Collaborators

Detail Information

Publications24

  1. doi request reprint Optical methods for noninvasive determination of carotenoids in human and animal skin
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Center of Experimental and Applied Cutaneous Physiology CCP, Chariteplatz 1, 10117 Berlin, Germany
    J Biomed Opt 18:61230. 2013
    ..The advantages, shortcomings, and limitations of the above-mentioned optical methods are discussed...
  2. doi request reprint Safety assessment by multiphoton fluorescence/second harmonic generation/hyper-Rayleigh scattering tomography of ZnO nanoparticles used in cosmetic products
    M E Darvin
    Center of Experimental and Cutaneous Physiology CCP, Department of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 25:219-26. 2012
    ..Taking advantage of this sensitivity, it was clearly shown that ZnO NPs penetrate only into the outermost layers of stratum corneum, furrows and into the orifices of the hair follicles and do not reach the viable epidermis...
  3. doi request reprint Comparison of two methods for noninvasive determination of carotenoids in human and animal skin: Raman spectroscopy versus reflection spectroscopy
    Maxim E Darvin
    Department of Dermatology, Venerology and Allergology, Center of Experimental and Cutaneous Physiology CCP, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Biophotonics 5:550-8. 2012
    ..A strong correlation between the carotenoid concentration determined by the RS and for the RRS system was achieved for human skin in vivo (R = 0.88) and for bovine udder skin in vitro (R = 0.81)...
  4. ncbi request reprint Analyses of the correlation between dermal and blood carotenoids in female cattle by optical methods
    Julia Klein
    Freie Universitat Berlin, Faculty of Veterinary Medicine, Clinic for Ruminants and Swine, Berlin, Germany
    J Biomed Opt 18:061219. 2013
    ..This demonstrates that the MSS is suitable for noninvasive assessment of dermal carotenoid concentrations in cattle...
  5. doi request reprint Dermal carotenoid level and kinetics after topical and systemic administration of antioxidants: enrichment strategies in a controlled in vivo study
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Venerology and Allergology, Berlin, Germany
    J Dermatol Sci 64:53-8. 2011
    ..The best prevention of the destructive action of free radicals in human skin is textile coverings, topical sunscreens and the development of a high antioxidative protective network...
  6. doi request reprint Kinetics of carotenoid distribution in human skin in vivo after exogenous stress: disinfectant and wIRA-induced carotenoid depletion recovers from outside to inside
    Joachim W Fluhr
    Charité Universitätsmedizin, Center of Experimental Applied Cutaneous Physiology, Department of Dermatology and Allergology, Berlin, Germany
    J Biomed Opt 16:035002. 2011
    ..We could show that the Raman microscopic spectroscopy is suited to analyze the carotenoid kinetic of stress effects and recovery...
  7. doi request reprint Topical beta-carotene protects against infra-red-light-induced free radicals
    Maxim E Darvin
    Center of Applied Cutaneous Physiology, Department of Dermatology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Exp Dermatol 20:125-9. 2011
    ..Resonance Raman spectroscopy can be used for the non-invasive measurements of carotenoids, which can be rated as marker substances of redox processes...
  8. doi request reprint Raman spectroscopic analysis of the carotenoid concentration in egg yolks depending on the feeding and housing conditions of the laying hens
    Karoline Hesterberg
    Charite University Hospital Berlin, Department of Dermatology and Allergology, Center of Experimental and Cutaneous Physiology CCP, Berlin, Germany
    J Biophotonics 5:33-9. 2012
    ..001). The kinetics of the carotenoid concentration in the egg yolks, depending on fodder, housing and weather conditions, were investigated...
  9. doi request reprint In vivo skin treatment with tissue-tolerable plasma influences skin physiology and antioxidant profile in human stratum corneum
    Joachim W Fluhr
    Universitätsmedizin Charité, Berlin, Department of Dermatology and Allergology, Center of Experimental and Cutaneous Physiology, Berlin, Germany
    Exp Dermatol 21:130-4. 2012
    ..Skin physiology parameters were influenced without damaging the skin or skin functions, indicating the safety of TTP under in vivo conditions...
  10. doi request reprint One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors
    Maxim E Darvin
    Charite Universitatsmedizin Berlin, Department of Dermatology, Chariteplatz 1, 10117 Berlin, Germany
    J Biomed Opt 13:044028. 2008
    ..During the summer and autumn months, an increase in the level of carotenoids in the skin was measured for all volunteers. The average "seasonal increase" of the carotenoid content in the skin was determined to be 1.26-fold...
  11. doi request reprint Determination of the antioxidative capacity of the skin in vivo using resonance Raman and electron paramagnetic resonance spectroscopy
    Stefan F Haag
    Department of Biology, Chemistry, and Pharmacy, Freie Universitat Berlin, Berlin, Germany
    Exp Dermatol 20:483-7. 2011
    ..Non-invasive measurements are of major interest for investigating the effects of stress, nutrition, diseases or pharmaceuticals on the antioxidative capacity of the human skin. However, only a few non-invasive methods are available...
  12. doi request reprint Noninvasive measurements of carotenoids in bovine udder by reflection spectroscopy
    Julia Klein
    Clinic for Ruminants and Swine, Faculty of Veterinary Medicine, Freie Universitat Berlin, Berlin, Germany
    J Biomed Opt 17:101514. 2012
    ..The carotenoid concentrations in "sensitive" and "robust" cows (evaluated by a temperament test) differed significantly (P<0.005), with higher concentrations observed in robust cows...
  13. doi request reprint In vivo distribution of carotenoids in different anatomical locations of human skin: comparative assessment with two different Raman spectroscopy methods
    Maxim E Darvin
    Center of Experimental Applied Cutaneous Physiology, Department of Dermatology and Allergology, Charite Universitatsmedizin, Berlin, Germany
    Exp Dermatol 18:1060-3. 2009
    ..Most of the antioxidants cannot be produced by the human organism. Thus, they have to be incorporated by food and beverages...
  14. doi request reprint Determination of the influence of IR radiation on the antioxidative network of the human skin
    Maxim E Darvin
    Center of Experimental and Applied Cutaneous Physiology CCP, Department of Dermatology and Allergology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Biophotonics 4:21-9. 2011
    ..Protection strategy for human skin against IR-induced free radicals based on the increase in the concentration of antioxidants by means of antioxidant-rich supplementation is discussed...
  15. doi request reprint Resonance Raman spectroscopy as an effective tool for the determination of antioxidative stability of cosmetic formulations
    Maxim E Darvin
    Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology and Allergology, Charite Universitatsmedizin Berlin, Germany
    J Biophotonics 3:82-8. 2010
    ..The measurements were carried out by using non-invasive resonance Raman spectroscopy for the detection of the carotenoid concentration in the cosmetic formulations...
  16. doi request reprint Carotenoids in human skin
    Juergen Lademann
    Center of Experimental and Cutaneous Physiology CCP, Department of Dermatology and Allergology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Exp Dermatol 20:377-82. 2011
    ..The measurements are highly suited for the development of anti-ageing strategies and can be efficiently used in the medical diagnostics and therapy control...
  17. doi request reprint Analyses of the correlation between dermal and blood carotenoids in female cattle by optical methods
    Julia Klein
    Freie Universitat Berlin, Faculty of Veterinary Medicine, Clinic for Ruminants and Swine, Königsweg 65, Berlin, Germany
    J Biomed Opt 18:061219. 2013
    ..This demonstrates that the MSS is suitable for noninvasive assessment of dermal carotenoid concentrations in cattle...
  18. doi request reprint Raman spectroscopic analysis of the increase of the carotenoid antioxidant concentration in human skin after a 1-week diet with ecological eggs
    Karoline Hesterberg
    Charite Universitatsmedizin Berlin, Department of Dermatology and Allergy, Center of Experimental and Applied Cutaneous Physiology, Chariteplatz 1, Berlin 10117, Germany
    J Biomed Opt 14:024039. 2009
    ..But in the case of egg consumption, ecological eggs from hens kept on pasture should be preferred to also receive a benefit for the skin...
  19. doi request reprint Analyses of the correlation between dermal and blood carotenoids in female cattle by optical methods
    Julia Klein
    Freie Universitat Berlin, Faculty of Veterinary Medicine, Clinic for Ruminants and Swine, Königsweg 65, Berlin, Germany
    J Biomed Opt 18:61219. 2013
    ..This demonstrates that the MSS is suitable for noninvasive assessment of dermal carotenoid concentrations in cattle...
  20. doi request reprint Bioavailability of natural carotenoids in human skin compared to blood
    Martina C Meinke
    Charite Universitatsmedizin Berlin, Center of Experimental and Cutaneous Physiology, Berlin, Germany
    Eur J Pharm Biopharm 76:269-74. 2010
    ..After supplementation had ended, the carotenoids decreased much faster in the blood than in the skin. The delayed decrease in the skin may indicate a peripheral buffer function of the skin for carotenoids...
  21. doi request reprint Dose-dependent vitamin C uptake and radical scavenging activity in human skin measured with in vivo electron paramagnetic resonance spectroscopy
    Anna Christina Lauer
    Department of Dermatology, Venereology and Allergology, Charite Universitatsmedizin Berlin, Berlin, Germany
    Skin Pharmacol Physiol 26:147-54. 2013
    ..In conclusion, orally administered vitamin C increases the radical-scavenging activity of the skin. The effect occurs fast and is enhanced with higher doses of vitamin C. ..
  22. pmc Serial non-invasive measurements of dermal carotenoid concentrations in dairy cows following recovery from abomasal displacement
    Julia Klein
    Clinic for Ruminants and Swine, Faculty of Veterinary Medicine, Freie Universitat Berlin, Berlin, Germany
    PLoS ONE 7:e47706. 2012
    ..These results indicate potential applications for reflection spectroscopy for non-invasive early detection of changes in the dermal carotenoid concentrations as a reflection of the antioxidant status in an animal...
  23. doi request reprint In vivo detection of basal cell carcinoma: comparison of a reflectance confocal microscope and a multiphoton tomograph
    Martina Ulrich
    Department of Dermatology, Allergology and Venerology, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    J Biomed Opt 18:61229. 2013
    ..The nucleus of elongated BCC cells is significantly longer than other measured normal skin cells, whereas the cell density and nucleus/cytoplasm ratio of BCC cannot be significantly distinguished from granular cells...
  24. doi request reprint Cutaneous lycopene and beta-carotene levels measured by resonance Raman spectroscopy: high reliability and sensitivity to oral lactolycopene deprivation and supplementation
    Ulrike Blume-Peytavi
    Clinical Research Center for Hair and Skin Science, Berlin, Germany
    Eur J Pharm Biopharm 73:187-94. 2009
    ..Thus, oral supplementation with lycopene led to an enrichment of beta-carotene in human skin, possibly due to the fact that carotenoids act in the skin as protection chains, with a natural protection against free radicals...