Heidi Danker-Hopfe

..1+/-2.5. This discrepancy between the subjects' claims of no sleep disturbance and their endorsing of PSQI items indicative of disturbed sleep probably reflects an adaptation in the perception of disturbed sleep...

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..Both, sleep at the subjective as well as at the objective level, can to a considerable degree be affected by life style factors, which hence have to be considered as potential confounders...

..The few significant results are not indicative of a negative impact on sleep architecture. From the present results there is no evidence for a sleep-disturbing effect of GSM 900 and WCDMA exposure...

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..Transcranial magnetic stimulation is a useful tool for investigating central cortical inhibitory mechanisms associated with GABAergic neurotransmission in psychiatric and neurological disorders...

..In this prospective, randomized, double-blind trial, we examined the efficacy and cognitive side effects of RULECT with three different (high dose) stimulus intensities (4×, 7× and 10× above the seizure threshold (ST))...

..Furthermore, measurement of motor cortical excitability may be a useful tool for investigating and monitoring inhibitory brain effects of antidepressant stimulation techniques like rTMS...

..These results indicate that cannabis is a possible risk factor for the development of schizophrenia. This might be reflected in the raised NGF-serum concentrations when both schizophrenia and long-term cannabis abuse prevail...

..In line with this hypothesis, disease onset was 5.2 years earlier in the cannabis-consuming group (p = 0.0111)...

..Present findings suggest that declarative and procedural memory consolidation during sleep is intact in BPD patients...

..The results of the present study do not provide any evidence of an EMF effect on human cognition, but they underline the necessity to control for time of day...

..Our results indicate that metabolic, state-dependent changes within the left DLPFC in major depressive disorder involve the glutamate system and can be reversed in a dose-dependent manner by rTMS...

..These variations of IRR most probably reflect changes of the sleep electroencephalography (EEG) with age and gender...

..A link between these two research domains on aging will be proposed and discussed on the basis of recent findings within the cognitive neuroscience of sleep...

..Recent findings in young adults suggest that rapid eye movement (REM) sleep plays a role in procedural memory consolidation. The significance of REM sleep for memory consolidation in old age has not yet been investigated...

..There were 3 patients with a HAM-A decrease of less than 15%. In those patients NGF rose only marginally. Hence, the increase in serum NGF seems to indicate good treatment response...

..19+/-38.96 pg/ml (SC) (S versus SC, p>0.05), respectively, after adequate antipsychotic treatment. We thus conclude that antipsychotic treatment leads to recovery of neural integrity, as indicated by renormalized NGF values...

..Furthermore, measurement of motor cortical excitability may be a useful tool for investigating and monitoring inhibitory brain effects of different antidepressant stimulation techniques...

..m. (p=0.279) and at 5 p.m. (p=0.627) as compared with the control day. We conclude that NGF serum levels do not change during acute stress, at least after this type of stressor...

..Prospective rTMS studies are necessary to validate the predictive value of the derived model...

..This article gives a short overview of current knowledge of sleep-related memory consolidation in healthy young adults and builds a bridge to psychiatry and depression, where further research is urgently needed...

..In conclusion, BDNF and NGF show substantial changes in this rodent model of chronic social stress, which is susceptible to antidepressant treatment with ES-CIT and therefore may constitute a neurobiological correlate for the disease...

..Thus, this study aims to replicate previous findings and explore patterns of response in drug-free patients...

..These results suggest that VNS is capable of changing motor cortical excitability in patients with depression...

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..We hypothesize, that BDNF might be involved in the behavioural and neurochemical mechanisms of aggressive behaviour...

..344, p<0.01), age and BDNF protein (r=-0.101, p=0.029) and BDNF and NGF serum levels (r=0.152, p=0.04). No other major influencing factors were found including gender, depression, and dementia...

..In accordance with this hypothesis, NGF values are "normal" in patients with persistent alcohol-related cognitive decline...

..5% of the recordings) are changed, can definitely be neglected. Thus, the validation study proved the high reliability and validity of the Somnolyzer 24 x 7 and demonstrated its applicability in clinical routine and sleep studies...

..This stability of our repetitive measurements over 4 weeks suggests that this neurotrophin may be an intraindividually solid marker at least in human serum...

..f. = 2) in all subjects. Given the small effect of this 5-HTT polymorphism on behaviour in previous studies, a lack of significant genotype differences in these tests could be due to considerable individual variability in these measures...