T Burmeister

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi request reprint Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group
    Thomas Burmeister
    Blood 112:918-9. 2008
  2. doi request reprint Erroneous class switching and false VDJ recombination: molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma
    Thomas Burmeister
    Charite, Med Klinik für Hämatologie, Onkologie und Tumorimmunologie, Berlin, Germany
    Mol Oncol 7:850-8. 2013
  3. pmc Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse
    Thomas Burmeister
    Klinik für Hämatologie, Charite CBF, Hindenburgdamm 30, 12200, Berlin, Germany
    Exp Hematol Oncol 1:6. 2012
  4. doi request reprint Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias
    Thomas Burmeister
    Charite, CBF, Medizinische Klinik für Hämatologie, Onkologie, Hindenburgdamm 30, 12200 Berlin, Germany
    DNA Repair (Amst) 10:1131-7. 2011
  5. pmc Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia
    Thomas Burmeister
    Med Klinik für Hämatologie Onkologie Hindenburgdamm 30, 12200 Berlin, Germany
    Haematologica 95:241-6. 2010
  6. doi request reprint The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin CBF, Medizinische Klinik III, Berlin, Germany
    Blood 113:4011-5. 2009
  7. doi request reprint A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32)
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin CBF, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Blood Cells Mol Dis 41:210-4. 2008
  8. ncbi request reprint Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus, Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Haematologica 92:1699-702. 2007
  9. ncbi request reprint A multiplex PCR for improved detection of typical and atypical BCR-ABL fusion transcripts
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Leuk Res 32:579-85. 2008
  10. pmc No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Retrovirology 4:11. 2007

Detail Information

Publications29

  1. doi request reprint Patients' age and BCR-ABL frequency in adult B-precursor ALL: a retrospective analysis from the GMALL study group
    Thomas Burmeister
    Blood 112:918-9. 2008
  2. doi request reprint Erroneous class switching and false VDJ recombination: molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma
    Thomas Burmeister
    Charite, Med Klinik für Hämatologie, Onkologie und Tumorimmunologie, Berlin, Germany
    Mol Oncol 7:850-8. 2013
    ..This study may serve as a model for the analysis of other IGH translocations in B-cell lymphoma. ..
  3. pmc Molecular monitoring of minimal residual disease in two patients with MLL-rearranged acute myeloid leukemia and haploidentical transplantation after relapse
    Thomas Burmeister
    Klinik für Hämatologie, Charite CBF, Hindenburgdamm 30, 12200, Berlin, Germany
    Exp Hematol Oncol 1:6. 2012
    ....
  4. doi request reprint Fine structure of translocation breakpoints within the major breakpoint region in BCR-ABL1-positive leukemias
    Thomas Burmeister
    Charite, CBF, Medizinische Klinik für Hämatologie, Onkologie, Hindenburgdamm 30, 12200 Berlin, Germany
    DNA Repair (Amst) 10:1131-7. 2011
    ....
  5. pmc Clinical features and prognostic implications of TCF3-PBX1 and ETV6-RUNX1 in adult acute lymphoblastic leukemia
    Thomas Burmeister
    Med Klinik für Hämatologie Onkologie Hindenburgdamm 30, 12200 Berlin, Germany
    Haematologica 95:241-6. 2010
    ..However, the prognostic impact of other rarer fusion genes is less well established in adult acute lymphoblastic leukemia than in the childhood form...
  6. doi request reprint The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia: results from the GMALL study group
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin CBF, Medizinische Klinik III, Berlin, Germany
    Blood 113:4011-5. 2009
    ..Characteristic features of MLL(+) patients were significantly lower CD10 expression, expression of the NG2 antigen, a higher white blood count at diagnosis, and female sex. Proposals are made for diagnostic assessment...
  7. doi request reprint A MLL-KIAA0284 fusion gene in a patient with secondary acute myeloid leukemia and t(11;14)(q23;q32)
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin CBF, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Blood Cells Mol Dis 41:210-4. 2008
    ..The expression of KIAA0284 in various tissues and hematologic diseases was investigated by real time quantitative PCR and turned out to be very low in all lymphatic and myeloid diseases investigated...
  8. ncbi request reprint Atypical BCR-ABL mRNA transcripts in adult acute lymphoblastic leukemia
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus, Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Haematologica 92:1699-702. 2007
    ..This corresponds to a prevalence of 1-2% of all BCR-ABL-positive cases. The clinical courses are reported and diagnostic proposals are made...
  9. ncbi request reprint A multiplex PCR for improved detection of typical and atypical BCR-ABL fusion transcripts
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Leuk Res 32:579-85. 2008
    ..We present here a novel, fast, and reliable multiplex PCR for improved detection of typical and atypical BCR-ABL transcripts...
  10. pmc No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Retrovirology 4:11. 2007
    ..The primer sequences were based on highly interspecies-conserved virus genome regions. We used this PCR to detect Deltaretroviruses in samples from adult patients with a variety of rare T-cell neoplasms in Germany...
  11. ncbi request reprint Molecular heterogeneity of sporadic adult Burkitt-type leukemia/lymphoma as revealed by PCR and cytogenetics: correlation with morphology, immunology and clinical features
    T Burmeister
    Charite, Campus Benjamin Franklin, Medizinische Klinik III, Berlin, Germany
    Leukemia 19:1391-8. 2005
    ..A total of 34 patients were treated according to the GMALL B-ALL therapy protocols and there was no significant difference in overall survival between patients with or without t(8;14)...
  12. ncbi request reprint Monitoring minimal residual disease by quantification of genomic chromosomal breakpoint sequences in acute leukemias with MLL aberrations
    T Burmeister
    Medizinische Klinik III, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, Berlin, Germany
    Leukemia 20:451-7. 2006
    ..An accurate and absolute quantification of the MRD level is possible. No reference to housekeeping genes is necessary and the target structure is much more stable than any mRNA fusion transcript...
  13. ncbi request reprint NUP214-ABL1 in adult T-ALL: the GMALL study group experience
    Thomas Burmeister
    Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    Blood 108:3556-9. 2006
    ..Based on the results, we have established and tested a novel PCR method for simplified detection of the NUP214-ABL1 fusion gene...
  14. ncbi request reprint A novel sporadic Burkitt lymphoma cell line (BLUE-1) with a unique t(6;20)(q15;q11.2) rearrangement
    Thomas Burmeister
    Medizinische Klinik III, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, Germany
    Leuk Res 30:1417-23. 2006
    ..Our findings are discussed in light of the current understanding of endemic and sporadic Burkitt lymphoma. BLUE-1 grows well in culture and should be a useful lymphoma research tool...
  15. doi request reprint Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group
    U Baak
    Charite Campus Benjamin Franklin, Medizinische Klinik III, Berlin, Germany
    Leukemia 22:1154-60. 2008
    ..Thus, patients with aberrant HOX11L2 expression should be considered early as candidates for intensified treatment regimes...
  16. doi request reprint Combined automated cell and flow cytometric analysis enables recognition of persistent polyclonal B-cell lymphocytosis (PPBL), a study of 25 patients
    M Schmidt-Hieber
    Medizinische Klinik III, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12200, Berlin, Germany
    Ann Hematol 87:829-36. 2008
    ..The observation of malignant lymphoma in a single patient implicates that evolution into a clonal malignant transformation may occasionally occur in PPBL...
  17. doi request reprint High BAALC expression predicts chemoresistance in adult B-precursor acute lymphoblastic leukemia
    Andrea Kühnl
    Medizinische Klinik III, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany
    Blood 115:3737-44. 2010
    ..Determination of BAALC might contribute to risk assessment of molecularly undefined adult B-precursor ALL...
  18. ncbi request reprint Expression of the human homologue of rat NG2 in adult acute lymphoblastic leukemia: close association with MLL rearrangement and a CD10(-)/CD24(-)/CD65s(+)/CD15(+) B-cell phenotype
    S Schwartz
    Medizinische Klinik III, Hämatologie, Onkologie und Transfusionsmedizin, Klinikum Benjamin Franklin, Freie Universitat, Berlin, Germany
    Leukemia 17:1589-95. 2003
    ..As NG2 is negative in non-malignant hematopoietic cells, this novel antigen might also serve in future studies as a powerful marker in monitoring minimal residual disease...
  19. ncbi request reprint A PCR primer system for detecting oncoretroviruses based on conserved DNA sequence motifs of animal retroviruses and its application to human leukaemias and lymphomas
    T Burmeister
    Freie Universitat Berlin, Medizinische Klinik III, Hindenburgdamm 30, 12200 Berlin, Germany
    J Gen Virol 82:2205-13. 2001
    ..The retrovirus detection system developed here may be used to confirm suspected retroviral involvement in other (malignant or nonmalignant) human diseases as well as to identify new animal retroviruses...
  20. doi request reprint Melting point assay for the JAK2 V617F mutation, comparison with amplification refractory mutation system (ARMS) in diagnostic samples, and implications for daily routine
    Sebastian Ochsenreither
    Department of Hematology and Oncology, Charite Berlin, Campus Benjamin Franklin, Berlin, Germany
    Mol Diagn Ther 14:185-90. 2010
    ..A multitude of methods has been applied to both qualitative and quantitative assessment of the mutational status of patients, without defining a gold standard for the daily diagnostic routine so far...
  21. doi request reprint Expression of interleukin 15 in primary adult acute lymphoblastic leukemia
    Shuling Wu
    Department of Hematology, Oncology and Transfusion Medicine, Campus Benjamin Franklin, Charity Medical Center, Hindenburgdamm 30, 12203 Berlin, Germany
    Cancer 116:387-92. 2010
    ..We determined the expression of IL-15 in lymphoblasts and evaluated its potential impact on the outcome in adult acute lymphoblastic leukemia (ALL)...
  22. pmc Prognostic implications of NOTCH1 and FBXW7 mutations in adult acute T-lymphoblastic leukemia
    Claudia D Baldus
    Charite, University Hospital Berlin, Campus Benjamin Franklin, Department of Hematology and Oncology, Hindenburgdamm 30 12203 Berlin, Germany
    Haematologica 94:1383-90. 2009
    ..However, the results of studies on the prognostic significance of NOTCH1 mutations in adult T-lymphoblastic leukemia remain controversial...
  23. ncbi request reprint Long distance polymerase chain reaction of ascites lymphoma cells aids diagnosis establishment of abdominal Burkitt's lymphoma and Burkitt-like lymphoma
    Kristoph Jahnke
    Department of Hematology, Oncolgy and Transfusion Medicine, Charite Universitatsmedizin Berlin, Germany
    Leuk Lymphoma 46:83-6. 2005
    ..Long distance PCR analysis of ascites lymphoma cells for the detection of the BL-typical c-myc rearrangement offers a convenient and rapid possibility of diagnosis verification in atypical or borderline cases of BL...
  24. pmc CD56 expression in T-cell acute lymphoblastic leukemia is associated with non-thymic phenotype and resistance to induction therapy but no inferior survival after risk-adapted therapy
    Lars Fischer
    Charite Campus Benjamin Franklin, Medizinische Klinik III, Berlin
    Haematologica 94:224-9. 2009
    ..Expression of CD56 has been associated with poor prognosis in acute myeloid leukemia and aggressive lymphoma...
  25. ncbi request reprint Skewed expression of natural-killer (NK)-associated antigens on lymphoproliferations of large granular lymphocytes (LGL)
    Lars Fischer
    Department of Hematology, Oncology and Transfusion Medicine, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Germany
    Hematol Oncol 24:78-85. 2006
    ..We consistently found a skewed expression pattern of novel NK markers as a pathological feature of LGLL. These antigens should be included in the diagnostic workup of this rare disease...
  26. ncbi request reprint Low ERG and BAALC expression identifies a new subgroup of adult acute T-lymphoblastic leukemia with a highly favorable outcome
    Claudia D Baldus
    Department of Hematology and Oncology, Charite, University Hospital Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Clin Oncol 25:3739-45. 2007
    ..We hypothesized that like ERG, BAALC expression might be of prognostic significance in acute T-lymphoblastic leukemia (T-ALL) and that ERG and BAALC expression together would better identify the patient's risk profile...
  27. ncbi request reprint Detection of subclinical systemic disease in primary CNS lymphoma by polymerase chain reaction of the rearranged immunoglobulin heavy-chain genes
    Kristoph Jahnke
    Department of Hematology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Clin Oncol 24:4754-7. 2006
    ....
  28. ncbi request reprint High expression of the ETS transcription factor ERG predicts adverse outcome in acute T-lymphoblastic leukemia in adults
    Claudia D Baldus
    Department of Hematology, Oncology and Transfusion Medicine, Charite, Campus Benjamin Franklin, University Hospital Berlin, Hindenburgdamm 30, 12203 Berlin, Germany
    J Clin Oncol 24:4714-20. 2006
    ..The adverse prognosis in T-ALL has not been attributed to cytogenetic or molecular aberrations. We have determined the prognostic impact of the oncogenic transcription factor ERG in T-ALL...
  29. ncbi request reprint Insertional polymorphisms of endogenous HERV-K113 and HERV-K115 retroviruses in breast cancer patients and age-matched controls
    Thomas Burmeister
    Medizinische Klinik III, Charite Campus Benjamin Franklin, 12200 Berlin, Germany
    AIDS Res Hum Retroviruses 20:1223-9. 2004
    ..This suggests that the two HERV-Ks do not play a pathogenetic role in the majority of breast cancer patients, though they may be involved in a minority of patients. The results are discussed...