Carsten Buning

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. doi Increased small intestinal permeability in ulcerative colitis: rather genetic than environmental and a risk factor for extensive disease?
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Berlin, Germany
    Inflamm Bowel Dis 18:1932-9. 2012
  2. doi [Luminal gastroenterology and inflammation]
    C Buning
    Medizinische Klinik m S Gastroenterologie, Hepatologie und Endokrinologie, Charite, Campus Mitte, Universitatsmedizin Berlin, Germany
    Dtsch Med Wochenschr 136:1197-9. 2011
  3. ncbi The interleukin-25 gene located in the inflammatory bowel disease (IBD) 4 region: no association with inflammatory bowel disease
    C Buning
    Humboldt University, Berlin, Germany
    Eur J Immunogenet 30:329-33. 2003
  4. ncbi Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocecal resection and are a risk factor for reoperation
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Humboldt University, Schumannstrasse 20 21, 10117 Berlin, Germany
    Aliment Pharmacol Ther 19:1073-8. 2004
  5. ncbi Keratin 8 Y54H and G62C mutations are not associated with inflammatory bowel disease
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Universitatsmedizin Berlin, Charite, Campus Mitte, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Dig Liver Dis 36:388-91. 2004
  6. ncbi NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Campus Mitte, Berlin, Germany
    World J Gastroenterol 11:407-11. 2005
  7. ncbi Conventional therapy for Crohn's disease
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Campus Mitte, Universitatsmedizin Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    World J Gastroenterol 12:4794-806. 2006
  8. ncbi Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Universitatsmedizin Berlin, Berlin, Germany
    Aliment Pharmacol Ther 26:1025-33. 2007
  9. ncbi DLG5 variants in inflammatory bowel disease
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Universitatsmedizin Berlin, Berlin, Germany
    Am J Gastroenterol 101:786-92. 2006
  10. doi The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease
    Daniel C Baumgart
    Division of Gastroenterology and Hepatology, Department of Medicine, Charite Medical School, Humboldt University of Berlin, Berlin, Germany
    Digestion 76:196-202. 2007

Collaborators

Detail Information

Publications22

  1. doi Increased small intestinal permeability in ulcerative colitis: rather genetic than environmental and a risk factor for extensive disease?
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Berlin, Germany
    Inflamm Bowel Dis 18:1932-9. 2012
    ..A disturbed epithelial barrier could play a pivotal role in ulcerative colitis (UC). We performed a family-based study analyzing in vivo gastrointestinal permeability in patients with UC, their healthy relatives, spouses, and controls...
  2. doi [Luminal gastroenterology and inflammation]
    C Buning
    Medizinische Klinik m S Gastroenterologie, Hepatologie und Endokrinologie, Charite, Campus Mitte, Universitatsmedizin Berlin, Germany
    Dtsch Med Wochenschr 136:1197-9. 2011
    ..Finally, an outlook is given on new and interesting therapeutic concepts in clostridium difficile colitis...
  3. ncbi The interleukin-25 gene located in the inflammatory bowel disease (IBD) 4 region: no association with inflammatory bowel disease
    C Buning
    Humboldt University, Berlin, Germany
    Eur J Immunogenet 30:329-33. 2003
    ....
  4. ncbi Mutations in the NOD2/CARD15 gene in Crohn's disease are associated with ileocecal resection and are a risk factor for reoperation
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Humboldt University, Schumannstrasse 20 21, 10117 Berlin, Germany
    Aliment Pharmacol Ther 19:1073-8. 2004
    ..Mutations within the NOD2/CARD15 gene have recently been shown to be associated with Crohn's disease...
  5. ncbi Keratin 8 Y54H and G62C mutations are not associated with inflammatory bowel disease
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Universitatsmedizin Berlin, Charite, Campus Mitte, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Dig Liver Dis 36:388-91. 2004
    ..Keratin 8 deficient mice display signs of colitis and diarrhoea characteristic for inflammatory bowel disease. Very recently, two keratin 8 mutations, Y54H and G62C, were identified...
  6. ncbi NOD2/CARD15 gene polymorphism in patients with inflammatory bowel disease: is Hungary different?
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Campus Mitte, Berlin, Germany
    World J Gastroenterol 11:407-11. 2005
    ..To analyse the impact of NOD2/CARD15 mutations on the clinical course of Crohn's disease patients from an eastern European country (Hungary)...
  7. ncbi Conventional therapy for Crohn's disease
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite Campus Mitte, Universitatsmedizin Berlin, Schumannstrasse 20 21, Berlin 10117, Germany
    World J Gastroenterol 12:4794-806. 2006
    ..We hope that this review offers a useful tool for clinicians in the challenging treatment of CD...
  8. ncbi Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis
    C Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Universitatsmedizin Berlin, Berlin, Germany
    Aliment Pharmacol Ther 26:1025-33. 2007
    ..A recent study reported that a non-synonymous single nucleotide polymorphism (rs11209026, p.Arg381Gln) located in the IL23R gene is a protective marker for inflammatory bowel disease...
  9. ncbi DLG5 variants in inflammatory bowel disease
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Universitatsmedizin Berlin, Berlin, Germany
    Am J Gastroenterol 101:786-92. 2006
    ..Furthermore, we evaluated whether DLG5 variants alter gastrointestinal permeability in Crohn's disease (CD)...
  10. doi The c.1-260C>T promoter variant of CD14 but not the c.896A>G (p.D299G) variant of toll-like receptor 4 (TLR4) genes is associated with inflammatory bowel disease
    Daniel C Baumgart
    Division of Gastroenterology and Hepatology, Department of Medicine, Charite Medical School, Humboldt University of Berlin, Berlin, Germany
    Digestion 76:196-202. 2007
    ..Therefore, the study of candidate genes involved in host pathogen interactions is of key interest...
  11. ncbi No association of the CARD8 (TUCAN) c.30T>A (p.C10X) variant with Crohn's disease: a study in 3 independent European cohorts
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Universitatsmedizin Berlin, Germany
    Inflamm Bowel Dis 14:332-7. 2008
    ..The aim of this study was to analyze the frequency of p.C10X in 3 independent European (IBD) cohorts from Germany, Hungary, and the Netherlands...
  12. ncbi Altered status of antioxidant vitamins and fatty acids in patients with inactive inflammatory bowel disease
    Susanne Hengstermann
    Charite Universitatsmedizin Berlin, Campus Mitte, Department of Gastroenterology, Chariteplatz 1, 10117 Berlin, Germany
    Clin Nutr 27:571-8. 2008
    ..We compared plasma levels of antioxidants and FA of patients with inactive IBD with active IBD and controls...
  13. doi The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action
    Matthias Prager
    Department of Medicine, Division of Gastroenterology, Infectiology and Rheumatology, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, Berlin 10117, Germany
    Int J Colorectal Dis 27:565-73. 2012
    ..We hypothesized that variants in genes occurring in pathways such as autophagy and IL23 signalling might contribute to CD by altering intestinal permeability...
  14. doi Circulating adipokines and the protective effects of hyperinsulinemia in inflammatory bowel disease
    Luzia Valentini
    Department of Gastroenterology, Hepatology and Endocrinology, Campus Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 25:172-81. 2009
    ....
  15. doi Is there a role for mannan-binding lectin in the diagnosis of inflammatory bowel disease?
    Christina Hoffmann
    Institute of Laboratory Medicine and Pathobiochemistry, Charite University Medicine Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
    Immunogenetics 62:231-5. 2010
    ..Neither the median MBL serum concentration nor the MBL2 genotype distribution differed significantly between cohorts. Measurement of MBL serum concentrations offers no benefit for the diagnosis of CD or UC...
  16. ncbi A study in three European IBD cohorts confirms that the ATG16L1 c.898A>G (p.Thr300Ala) variant is a susceptibility factor for Crohn's disease
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    J Crohns Colitis 1:70-6. 2007
    ..898A>G, p.Thr300Ala) within ATG16L1 confers susceptibility to Crohn's disease (CD). We analyzed ATG16L1 c.898A>G in three independent European inflammatory bowel disease (IBD) cohorts from Germany, Hungary and the Netherlands...
  17. ncbi Introducing genetic testing for adult-type hypolactasia
    Carsten Buning
    Department of Gastroenterology, Hepatology and Endocrinology, Charite, Campus Mitte, Humboldt University of Berlin, Berlin, Germany
    Digestion 71:245-50. 2005
    ..To evaluate genotyping for two DNA variants (c.1993+327C>T and c.1438+117G>A), recently found to be associated with adult-type hypolactasia, in the diagnosis of lactose intolerance...
  18. ncbi Malnutrition and impaired muscle strength in patients with Crohn's disease and ulcerative colitis in remission
    Luzia Valentini
    Department of Gastroenterology, Hepatology and Endocrinology, CCM, Charite Universitatsmedizin Berlin, Berlin, Germany
    Nutrition 24:694-702. 2008
    ..In addition, possible effects of gender, malnutrition, inflammation, and previous prednisolone therapy were investigated...
  19. pmc Impact of pain on health-related quality of life in patients with inflammatory bowel disease
    Anja Schirbel
    Division of Gastroenterology and Hepatology, Department of Medicine, Charite Campus Virchow Clinic, Universitatsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany
    World J Gastroenterol 16:3168-77. 2010
    ..To evaluate intensity, localization and cofactors of pain in Crohn's disease and ulcerative colitis patients in connection with health-related quality of life (HRQOL) and disease activity...
  20. ncbi PTGER4 modulating variants in Crohn's disease
    Matthias Prager
    Department of Hepatology and Gastroenterology, Universitatsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Int J Colorectal Dis 29:909-15. 2014
    ..We analyzed these variants in a large German inflammatory bowel disease (IBD) cohort and searched for a potential phenotype association...
  21. ncbi Increased expression of CD40 ligand on activated T cells of patients with colon cancer
    Carsten Buning
    Medizinische Klinik mit Schwerpunkt Gastroenterologie, Hepatologie und Endokrinologie, Charite, Campus Mitte der Humboldt Universität zu Berlin, 10117 Berlin, Germany
    Clin Cancer Res 8:1147-51. 2002
    ..Identifying the cell surface molecules on the T cells that may be involved in this antitumor response may help to elucidate immunological factors influencing the biology of human tumors...
  22. doi Colonic expression of the peptide transporter PEPT1 is downregulated during intestinal inflammation and is not required for NOD2-dependent immune activation
    Tilo Wuensch
    1Technische Universität München, ZIEL Research Center for Nutrition and Food Science, Biochemistry Unit, Weihenstephan, Germany 2Institute of Pathology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany 3Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France 4Université Lille Nord de France, Lille, France 5Centre national de la recherche scientifique, Unite Mixte de Recherche, Lille, France 6Institut National de la Santé et de la Recherche Médicale, Lille, France 7Technische Universität München, ZIEL Research Center for Nutrition and Food Science, Biofunctionality Unit, Weihenstephan, Germany 8Institute of Microbiology and Hygiene, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany 9Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, North Carolina 10Department of Gastroenterology, Infectiology and Rheumatology, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany 11Institute of Transfusion Medicine and Immunology, Medical Faculty Mannheim, Heidelberg University, German Red Cross Blood Service of Baden Württemberg Hessen, Mannheim, Germany
    Inflamm Bowel Dis 20:671-84. 2014
    ..To better define the pathological relevance of this transporter, we analyzed PEPT1 expression during intestinal inflammation and studied the susceptibility of Pept1-deficient (Pept1) mice to experimental colitis...