Chris Braumann

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint The influence of adhesion prophylactic substances and taurolidine/heparin on local recurrence and intraperitoneal tumor growth after laparoscopic-assisted bowel resection of colon carcinoma in a rat model
    I Opitz
    Department of General, Visceral, Vascular, and Thoracic Surgery, Humboldt University Berlin, Charite Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    Surg Endosc 17:1098-104. 2003
  2. ncbi request reprint Effects of taurolidine and octreotide on tumor growth and lipid peroxidation after staging-laparoscopy in ductal pancreatic cancer
    M Kilian
    Clinic of General, Visceral, Vascular and Thoracic Surgery, Schumannstrasse 20 21, Charite Campus Mitte, Berlin 10117, Germany
    Prostaglandins Leukot Essent Fatty Acids 69:261-7. 2003
  3. ncbi request reprint Local and systemic chemotherapy with taurolidine and taurolidine/heparin in colon cancer-bearing rats undergoing laparotomy
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery Humboldt University of Berlin, Charite, Berlin, Germany
    Clin Exp Metastasis 20:387-94. 2003
  4. ncbi request reprint Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitatsmedizin Berlin, Monbijoustrasse 2, 10117 Berlin, Germany
    Mini Rev Med Chem 8:421-8. 2008
  5. ncbi request reprint The tumor suppressive reagent taurolidine inhibits growth of malignant melanoma--a mouse model
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Surg Res 143:372-8. 2007
  6. ncbi request reprint Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Schumannstrasse 20 21, Berlin, Germany
    Clin Exp Metastasis 22:77-83. 2005
  7. ncbi request reprint High doses of taurolidine inhibit advanced intraperitoneal tumor growth in rats
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Humboldt University, Berlin, Germany
    J Surg Res 129:129-35. 2005
  8. ncbi request reprint Pneumatosis intestinalis--a pitfall for surgeons?
    C Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Humboldt University of Berlin, Charite Campus Mitte, Germany
    Scand J Surg 94:47-50. 2005
  9. doi request reprint Leukopoiesis is not affected after intravenous treatment with the novel antineoplastic agent taurolidine. Results of an experimental study in rats
    C Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitatsmedizin Berlin, Berlin, Germany
    Eur Surg Res 40:341-6. 2008
  10. doi request reprint Robotic-assisted laparoscopic and thoracoscopic surgery with the da Vinci system: a 4-year experience in a single institution
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Germany
    Surg Laparosc Endosc Percutan Tech 18:260-6. 2008

Collaborators

Detail Information

Publications43

  1. ncbi request reprint The influence of adhesion prophylactic substances and taurolidine/heparin on local recurrence and intraperitoneal tumor growth after laparoscopic-assisted bowel resection of colon carcinoma in a rat model
    I Opitz
    Department of General, Visceral, Vascular, and Thoracic Surgery, Humboldt University Berlin, Charite Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    Surg Endosc 17:1098-104. 2003
    ....
  2. ncbi request reprint Effects of taurolidine and octreotide on tumor growth and lipid peroxidation after staging-laparoscopy in ductal pancreatic cancer
    M Kilian
    Clinic of General, Visceral, Vascular and Thoracic Surgery, Schumannstrasse 20 21, Charite Campus Mitte, Berlin 10117, Germany
    Prostaglandins Leukot Essent Fatty Acids 69:261-7. 2003
    ..05). In conclusion this study showed that laparoscopic irrigation with taurolidine after pancreatic biopsy inhibited tumor growth in ductal pancreatic adenocarcinoma...
  3. ncbi request reprint Local and systemic chemotherapy with taurolidine and taurolidine/heparin in colon cancer-bearing rats undergoing laparotomy
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery Humboldt University of Berlin, Charite, Berlin, Germany
    Clin Exp Metastasis 20:387-94. 2003
    ..Neither the intraperitoneal nor the intravenous application or the combination of the two agents influenced the subcutaneous tumor growth. The substances did not alter the changes of peripheral leukocytes...
  4. ncbi request reprint Novel anti-angiogenic compounds for application in tumor therapy - COP9 signalosome-associated kinases as possible targets
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitatsmedizin Berlin, Monbijoustrasse 2, 10117 Berlin, Germany
    Mini Rev Med Chem 8:421-8. 2008
    ..Whereas curcumin and emodin can act via inhibition of COP9 signalosome-associated kinases, taurolidine blocks protein biosynthesis...
  5. ncbi request reprint The tumor suppressive reagent taurolidine inhibits growth of malignant melanoma--a mouse model
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Surg Res 143:372-8. 2007
    ..TRD has been shown to induce apoptosis of melanoma cells in vitro. Therefore, the effects of TRD on disseminated melanoma were evaluated in a mice model...
  6. ncbi request reprint Effects of increasing doses of a bolus injection and an intravenous long-term therapy of taurolidine on subcutaneous (metastatic) tumor growth in rats
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Schumannstrasse 20 21, Berlin, Germany
    Clin Exp Metastasis 22:77-83. 2005
    ..Thus, an intravenous long-term therapy with taurolidine was investigated in rats after administration of a subcutaneous tumor load. VEGF and TNFalpha production and their effects on tumor growth have not been elucidated so far...
  7. ncbi request reprint High doses of taurolidine inhibit advanced intraperitoneal tumor growth in rats
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Humboldt University, Berlin, Germany
    J Surg Res 129:129-35. 2005
    ..Thus far, no animal studies have been published concerning the systemic or local toxicity and the effectiveness of long-term intraperitoneal (i.p.) and intravenous (i.v.) administration on advanced tumor growths...
  8. ncbi request reprint Pneumatosis intestinalis--a pitfall for surgeons?
    C Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Humboldt University of Berlin, Charite Campus Mitte, Germany
    Scand J Surg 94:47-50. 2005
    ..Therefore, the treatment of PI can present as a major dilemma for the surgeon...
  9. doi request reprint Leukopoiesis is not affected after intravenous treatment with the novel antineoplastic agent taurolidine. Results of an experimental study in rats
    C Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitatsmedizin Berlin, Berlin, Germany
    Eur Surg Res 40:341-6. 2008
    ..The aim of our study was to investigate the effects on leukopoiesis when the antineoplastic agent taurolidine (TRD) is administered by a bolus injection or during repetitive treatment (21 cycles) over 7 days in rats...
  10. doi request reprint Robotic-assisted laparoscopic and thoracoscopic surgery with the da Vinci system: a 4-year experience in a single institution
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Germany
    Surg Laparosc Endosc Percutan Tech 18:260-6. 2008
    ..We set up a pilot study to evaluate the efficacy of telerobotic surgery using the da Vinci system for several procedures for which traditional laparoscopy (or thoracoscopy) is a standard approach in a single institution...
  11. doi request reprint Application of a solid tumor model to evaluate tumor recurrence after an open or laparoscopic rectal resection in rats
    Chris Braumann
    Department of General, Visceral, Thoracic, and Vascular Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, Berlin, Germany
    Surg Laparosc Endosc Percutan Tech 18:348-52. 2008
    ..We used a solid tumor model to evaluate the influence of laparotomy versus laparoscopy on tumor growth after curative resection for rectal cancer in rats...
  12. ncbi request reprint Laparoscopic removal of ingested pin penetrating the gastric wall in an immunosuppressed patient
    C Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Berlin, Germany
    Surg Endosc 18:870. 2004
    ..The patient recovered uneventfully and was discharged in good health on the 5th day after the procedure. Laparoscopy should be considered the approach of choice for the removal of ingested foreign bodies when surgery is indicated...
  13. ncbi request reprint Laparoscopic removal of ingested pin penetrating the gastric wall in an immunosuppressed patient
    C Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Berlin, Germany
    Surg Endosc 18:870. 2004
    ..The patient recovered uneventfully and was discharged in good health on the 5th day after the procedure. Laparoscopy should be considered the approach of choice for the removal of ingested foreign bodies when surgery is indicated...
  14. pmc Taurolidine reduces the tumor stimulating cytokine interleukin-1beta in patients with resectable gastrointestinal cancer: a multicentre prospective randomized trial
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Humboldt University, Chariteplatz 1, 10117 Berlin, Germany
    World J Surg Oncol 7:32. 2009
    ..The effect of additional treatment strategies with antineoplastic agents on intraperitoneal tumor stimulating interleukin levels are unclear. Taurolidine and Povidone-iodine have been mainly used for abdominal lavage in Germany and Europe...
  15. doi request reprint Multimodal perioperative rehabilitation in elective conventional resection of colonic cancer: results from the German Multicenter Quality Assurance Program 'Fast-Track Colon II'
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Charité University of Medicine, Berlin, Germany
    Dig Surg 26:123-9. 2009
    ..In 2005, a nationwide quality assurance program was initiated in Germany in an unselected patient population...
  16. doi request reprint Wound healing is not impaired in rats undergoing perioperative treatment with the antineoplastic agent taurolidine
    C Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, Berlin, Germany
    Eur Surg Res 42:91-6. 2009
    ..The aim of this study was to determine whether an intravenous or an intraperitoneal application of the antineoplastic agent taurolidine (TRD) impairs wound healing in the absence of tumor load in rats...
  17. doi request reprint Clinical experiences derived from implementation of an easy to use concept for treatment of wound healing by secondary intention and guidance in selection of appropriate dressings
    Chris Braumann
    Department of General and Visceral Surgery, Campus Mitte, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Int Wound J 8:253-60. 2011
    ..On the basis of the wound healing results, patients' evaluation of treatment and the clinicians' and staff experiences, this concept was implemented at different Surgical Departments of the Charité-Universitätsmedizin in Berlin...
  18. ncbi request reprint The clear cell adenocarcinoma of the colon: case report and review of the literature
    Chris Braumann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Charite Campus Mitte, Humboldt University, Schumannstrasse 20 21, 10117 Berlin, Germany
    Int J Colorectal Dis 19:264-7. 2004
    ..We report a case of such a tumor in the left colonic flexure of an 89-year-old patient who was treated surgically in our Department. We also review published cases which include primary colonic clear cell formations...
  19. ncbi request reprint Influence of intraperitoneal application of taurolidine/heparin on expression of adhesion molecules and colon cancer in rats undergoing laparoscopy
    Eva Bobrich
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitaetsmedizin Berlin, Medical Faculty Charité, Humboldt University, Schumannstr, Berlin, Germany
    J Surg Res 137:75-82. 2007
    ..It might be that the anti-adherent activities of these agents are responsible for this effect. In this study we investigated the adhesion molecules E-cadherin, beta1-integrin, and CD44...
  20. doi request reprint Multimodal approach for treatment of peritoneal surface malignancies in a tumour-bearing rat model
    Wieland Raue
    Department of General, Visceral, Vascular and Thoracic Surgery, University Medicine Berlin, Charite Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Int J Colorectal Dis 25:245-50. 2010
    ..The feasibility of an established rat model with a peritoneal surface malignancy from colorectal origin for treatment investigation should be examined in this study...
  21. ncbi request reprint Taurolidine--a new drug with anti-tumor and anti-angiogenic effects
    Christoph A Jacobi
    Department of General, Visceral, Vascular and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Berlin, Germany
    Anticancer Drugs 16:917-21. 2005
    ..Prospective clinical studies are currently investigating the efficacy of TRD on local and metastatic tumor growth in different malignancies...
  22. doi request reprint Long-term results of quality of life after standard laparoscopic vs. robot-assisted laparoscopic fundoplications for gastro-oesophageal reflux disease. A comparative clinical trial
    Jens Hartmann
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Int J Med Robot 5:32-7. 2009
    ..The role of telematic surgical approach in gastro-oesophageal reflux disease (GERD) is still unclear...
  23. ncbi request reprint Computer-assisted laparoscopic repair of "upside-down" stomach with the Da Vinci system
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Berlin, Germany
    Surg Laparosc Endosc Percutan Tech 15:285-9. 2005
    ..Technological evolution will perhaps diminish the current problems and the cost associated with robotic surgery...
  24. doi request reprint Evaluation of postoperative long-term quality of life after laparoscopic anterior partial fundoplication in the treatment of gastroesophageal reflux disease
    Wieland Raue
    Department of General, Visceral, Vascular and Thoracic Surgery, University of Medicine Berlin, Charite Campus Mitte, Berlin, Germany
    Dig Surg 26:413-7. 2009
    ..In the treatment of gastroesophageal reflux disease (GERD), anterior fundoplications are emphasized for their lower risk of complications compared to the posterior approach...
  25. ncbi request reprint Impact of taurolidin and octreotide on liver metastasis and lipid peroxidation after laparoscopy in chemical induced ductal pancreatic cancer
    Maik Kilian
    Clinic of General, Visceral, Vascular and Thoracic Surgery, Humboldt University, Schumannstr 2 21, 10117 Berlin, Germany
    Invest New Drugs 23:157-64. 2005
    ..Therefore we evaluated the effects of laparoscopic lavage with taurolidin and Octreotide on liver metastasis after staging laparoscopy in ductal pancreatic cancer...
  26. doi request reprint First surgical tumour reduction of peritoneal surface malignancy in a rat's model
    Jens Hartmann
    Department of General, Visceral, Vascular and Thoracic Surgery, University Medicine Berlin, Charite Campus Mitte, Berlin, Germany
    Clin Exp Metastasis 25:445-9. 2008
    ..This animal model could be an important step for investigation of multimodal treatment options and toxicity in treatment regimens of peritoneal surface malignancy...
  27. ncbi request reprint Surgical treatment of gastroesophageal reflux disease and upside-down stomach using the Da Vinci robotic system. A prospective study
    Jens Hartmann
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    J Gastrointest Surg 12:504-9. 2008
    ..This compensates long setup- and operating times. Disadvantages are the high costs, the time to master the setup/system and the necessity of exact trocar positioning...
  28. ncbi request reprint Computer-assisted laparoscopic colon resection with the Da Vinci system: our first experiences
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Medical Faculty Charité, Humboldt University, Berlin, Germany
    Dis Colon Rectum 48:1820-7. 2005
    ..This study was designed to assess the value of robots in colonic laparoscopic surgery. We present our first cases of robotic-assisted colectomies...
  29. ncbi request reprint The tumor-suppressive reagent taurolidine is an inhibitor of protein biosynthesis
    Chris Braumann
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite, Universitatsmedizin Berlin, Berlin, Germany
    Int J Cancer 112:225-30. 2004
    ..Taurolidine also suppressed protein expression in bacteria. Based on our data, we conclude that taurolidine blocks a fundamental early phase of translation, which might explain its effects as a disinfectant and inhibitor of tumor growth...
  30. ncbi request reprint Effects of taurolidine and octreotide on port site and liver metastasis after laparoscopy in an animal model of pancreatic cancer
    F A Wenger
    Department of General, Visceral, Vascular and Thoracic Surgery, Humboldt University of Berlin, Germany
    Clin Exp Metastasis 19:169-73. 2002
    ..8% after saline, in 37.5% after octreotide and in 0% after taurolidine irrigation (P < 0.05). Thus port site metastasis was effectively prevented by taurolidine irrigation after staging-laparoscopy in pancreatic cancer...
  31. ncbi request reprint Strangulated appendix within a trocar site incisional hernia following laparoscopic low anterior rectal resection. A case report
    Ch Menenakos
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite Universitaetsmedizin Berlin, Campus Mitte, Berlin, Germany
    Acta Chir Belg 109:411-3. 2009
    ..Subsequent surgery surprisingly revealed that the right lower trocar point incisional hernia contained a strangulated appendix. Routine appendectomy was performed and the hernias were repaired using a typical sublay technique...
  32. ncbi request reprint [Impact of pneumoperitoneum on expression of E-cadherin, CD44v6 and CD54 (ICAM-1) on HT-29 colon-carcinoma cells]
    J Ordemann
    Klinik fUr Allgemein, Viszeral, Gefäss und Thoraxchirurgie, Medizinische Fakultät der Charité, Universitatsmedizin Berlin, Campus Mitte
    Zentralbl Chir 130:405-9. 2005
    ..Therefore we investigated the influence of CO2 and Helium insufflation on the in-vitro expression of E-Cadherin, CD44v6 and CD54 (ICAM-1) on HT-29 colon carcinoma cells...
  33. ncbi request reprint Stress takotsubo cardiomyopathy after pylorus preserving pancreaticoduodenectomy for cancer. A case report
    G Koplin
    Department of General, Visceral, Vascular and Thoracic Surgery, Charite, University Medicine Berlin, Campus Mitte, Berlin
    Acta Anaesthesiol Belg 60:99-100. 2009
    ..No residual problems remained but the cause of Takotsubo could not be identified. Analyzing the current knowledge, a feasible preoperative screening for this severe condition seems to be quite impossible...
  34. doi request reprint [Minimally invasive thymus surgery]
    J C Rückert
    Klinik fUr Allgemein, Viszeral, Gefäss und Thoraxchirurgie, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117, Berlin, Germany
    Chirurg 79:18, 20-5. 2008
    ..There are special advantages of this technique for thymectomy. An overview of the development and experiences with minimally invasive thymectomy is presented, including data from the largest series published so far...
  35. ncbi request reprint Morphology of the rat peritoneum after carbon dioxide and helium pneumoperitoneum: a scanning electron microscopic study
    J Ordemann
    Department of General, Visceral, Vascular, and Thoracic Surgery, Medical Faculty, Humboldt University Shumannstrasse 20 21, 10117 Berlin, Germany
    Surg Endosc 18:1389-93. 2004
    ..The influence of carbon dioxide (CO(2)) and helium pneumoperitoneum on the morphology of the peritoneum was examined...
  36. ncbi request reprint The impact of conventional and laparoscopic colon resection (CO2 or helium) on intraperitoneal adhesion formation in a rat peritonitis model
    C A Jacobi
    Department of General, Visceral, Vascular, and Thoracic Surgery, Charite, Humboldt University of Berlin, Schumann Strasse 20 21, D 10098 Berlin, Germany
    Surg Endosc 15:380-6. 2001
    ....
  37. pmc Retroperitoneal Castleman's tumor and paraneoplastic pemphigus: report of a case and review of the literature
    Charalambos Menenakos
    Department of General, Visceral, Vascular and Thoracic Surgery, Universitaetsmedizin Berlin, Charite Campus Mitte, Berlin, Germany
    World J Surg Oncol 5:45. 2007
    ..Its etiology and pathogenesis are unclear. The disease can be occasionally associated with a paraneoplastic pemphigus (PNP), an autoimmune mucocutaneous disorder commonly seen in neoplasms of lymphocytic origin...
  38. doi request reprint Malignant melanoma metastasis as a cause of small-bowel perforation
    Nikolaos Tsilimparis
    Klinik fUr Allgemein, Visceral, Gefäss und Thoraxchirurgie, Charite Campus Mitte, Universitatsmedizin Berlin, Germany
    Onkologie 32:356-8. 2009
    ..In most cases, malignant melanoma metastasizes over the lymph vessels to parenchymal organs. Symptomatic metastases are found in the gastrointestinal tract in only about 2% of the patients...
  39. ncbi request reprint Identification of HIV-1 Tat peptides for future therapeutic angiogenesis
    Mahmoud Ismail
    Department of Surgery, Universitatsmedizin Berlin, Berlin, Germany
    Eur J Haematol 77:157-65. 2006
    ..They represent the basis for the development of novel pro-angiogenic drugs for future therapeutic angiogenesis, which might be applied for treatment of unreconstructible critical limb ischemia...
  40. ncbi request reprint Immunomodulatory changes in patients with colorectal cancer
    J Ordemann
    Department of General, Visceral, Vascular, Thoracic Surgery, Charite, Medical School, Medical Faculty, Humboldt University, Berlin, Germany
    Int J Colorectal Dis 17:37-41. 2002
    ..Solid tumors are frequently accompanied by a depressed cellular and humoral immunity. This study analyzed changes these factors in colorectal cancer patients...
  41. ncbi request reprint [Distal trachea and bronchial large lesions and suture reinforcement with Polyglicol Acid (PGA) patch. First clinical experience]
    T Harenberg
    Divisione di Chirurgia Generale, Viscerale, Vascolare e Toracica, Chartié Universitätsmedizin Berlin, Campus Mitte, Berlin
    G Chir 31:10-5. 2010
    ..The outcome is mainly influenced by thorough diagnostics, severity of the lesions, and urgent treatment. New materials are used to reduce the tension at the sutured points during ventilation...
  42. ncbi request reprint Schwannoma of the colon mimicking carcinoma: a case report and literature review
    Chris Braumann
    Int J Colorectal Dis 22:1547-8. 2007