Michael Bauer

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi request reprint Bone mineral density during maintenance treatment with supraphysiological doses of levothyroxine in affective disorders: a longitudinal study
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    J Affect Disord 83:183-90. 2004
  2. ncbi request reprint Lithium augmentation therapy in refractory depression: clinical evidence and neurobiological mechanisms
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Hospital, Humboldt University at Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Can J Psychiatry 48:440-8. 2003
  3. ncbi request reprint Lithium augmentation therapy in refractory depression-update 2002
    Michael Bauer
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte Humboldt Universitat zu Berlin, Schumannstr 20 21, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 253:132-9. 2003
  4. ncbi request reprint Do antidepressants influence mood patterns? A naturalistic study in bipolar disorder
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Schumannstrasse 20 21, 10117 Berlin, Germany
    Eur Psychiatry 21:262-9. 2006
  5. ncbi request reprint Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomania
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Schumannstr 20 21, 10117 Berlin, Germany
    J Affect Disord 96:101-5. 2006
  6. ncbi request reprint Temporal relation between sleep and mood in patients with bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Bipolar Disord 8:160-7. 2006
  7. ncbi request reprint Thyroid, brain and mood modulation in affective disorder: insights from molecular research and functional brain imaging
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S215-21. 2003
  8. ncbi request reprint Supraphysiological doses of L-thyroxine in the maintenance treatment of prophylaxis-resistant affective disorders
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite, Humboldt University of Berlin, Berlin, Germany
    Neuropsychopharmacology 27:620-8. 2002
  9. ncbi request reprint Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S250-4. 2003
  10. ncbi request reprint Epidemiology of bipolar disorders
    Michael Bauer
    Charite University Medicine Berlin, Campus Charité Mitte CCM, Department of Psychiatry and Psychotherapy, Berlin, Germany
    Epilepsia 46:8-13. 2005

Collaborators

Detail Information

Publications128 found, 100 shown here

  1. ncbi request reprint Bone mineral density during maintenance treatment with supraphysiological doses of levothyroxine in affective disorders: a longitudinal study
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    J Affect Disord 83:183-90. 2004
    ....
  2. ncbi request reprint Lithium augmentation therapy in refractory depression: clinical evidence and neurobiological mechanisms
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Hospital, Humboldt University at Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Can J Psychiatry 48:440-8. 2003
    ..It also examines hypotheses on the mode of action of lithium augmentation, with a focus on serotonin (5-HT) and neuroendocrine systems, and proposes recommendations for future research...
  3. ncbi request reprint Lithium augmentation therapy in refractory depression-update 2002
    Michael Bauer
    Klinik fur Psychiatrie und Psychotherapie, Charite Campus Mitte Humboldt Universitat zu Berlin, Schumannstr 20 21, 10117, Berlin, Germany
    Eur Arch Psychiatry Clin Neurosci 253:132-9. 2003
    ..Therefore, it should be considered a first-line treatment strategy in patients with major depression who do not adequately respond to standard antidepressants...
  4. ncbi request reprint Do antidepressants influence mood patterns? A naturalistic study in bipolar disorder
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Schumannstrasse 20 21, 10117 Berlin, Germany
    Eur Psychiatry 21:262-9. 2006
    ..Antidepressants had little impact on the mood patterns of bipolar patients taking mood stabilizers...
  5. ncbi request reprint Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomania
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Schumannstr 20 21, 10117 Berlin, Germany
    J Affect Disord 96:101-5. 2006
    ..Using daily self-reported mood ratings, we studied the impact of changing the length requirement on the number of hypomanic episodes in patients with bipolar disorder...
  6. ncbi request reprint Temporal relation between sleep and mood in patients with bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Bipolar Disord 8:160-7. 2006
    ..Sleep disturbances are frequent warning signs of both mania and depression. This study used cross correlation analysis to characterize the relationship between mood, sleep and bedrest in longitudinal data...
  7. ncbi request reprint Thyroid, brain and mood modulation in affective disorder: insights from molecular research and functional brain imaging
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S215-21. 2003
    ..Theses studies confirm that thyroid hormones are active in modulating metabolic function in the mature adult brain, and provide intriging neuroanatomic clues that may guide future research...
  8. ncbi request reprint Supraphysiological doses of L-thyroxine in the maintenance treatment of prophylaxis-resistant affective disorders
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite, Humboldt University of Berlin, Berlin, Germany
    Neuropsychopharmacology 27:620-8. 2002
    ..In conclusion, adjunctive treatment with L-thyroxine in supraphysiological doses may be an effective strategy in the maintenance treatment of patients with prophylaxis-resistant affective disorders...
  9. ncbi request reprint Implications of the neuroprotective effects of lithium for the treatment of bipolar and neurodegenerative disorders
    M Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S250-4. 2003
    ..We propose to examine the effect of long-term lithium treatment on neurocognitive functioning of bipolar patients and the use of lithium in the treatment of chronic neuropsychiatric disorders...
  10. ncbi request reprint Epidemiology of bipolar disorders
    Michael Bauer
    Charite University Medicine Berlin, Campus Charité Mitte CCM, Department of Psychiatry and Psychotherapy, Berlin, Germany
    Epilepsia 46:8-13. 2005
    ..This article also discusses risk factors, comorbid conditions, course of illness, as well as the individual and socioeconomic impact of bipolar disorders...
  11. ncbi request reprint Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression
    M Bauer
    Neuropsychiatric Institute and Hospital, University of California Los Angeles, CA, USA
    Mol Psychiatry 10:456-69. 2005
    ..We conclude that bipolar depressed patients have abnormal function in prefrontal and limbic brain areas. L-T(4) may improve mood by affecting circuits involving these areas, which have been previously implicated in affective disorders...
  12. ncbi request reprint Mood changes related to antidepressants: a longitudinal study of patients with bipolar disorder in a naturalistic setting
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Schumannstr 20 21, 10117 Berlin, Germany
    Psychiatry Res 133:73-80. 2005
    ..The primary difference in pattern between the groups was the time spent in depressed or normal mood, with minor daily mood variations...
  13. ncbi request reprint Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Berlin, Germany
    Bipolar Disord 6:67-74. 2004
    ....
  14. doi request reprint Efficacy of an algorithm-guided treatment compared with treatment as usual: a randomized, controlled study of inpatients with depression
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Germany
    J Clin Psychopharmacol 29:327-33. 2009
    ..This single-center prospective study compared the efficacy and effects on treatment prescriptions of an algorithm-guided treatment regimen with treatment as usual (TAU) in depressed inpatients...
  15. doi request reprint Outcomes of 1014 naturalistically treated inpatients with major depressive episode
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Germany
    Eur Neuropsychopharmacol 20:346-55. 2010
    ..Of those who ultimately achieved response more than 40% did so within the first 2weeks. An individualized naturalistic inpatient treatment approach appears to be beneficial in terms of effectiveness...
  16. ncbi request reprint Clinical predictors of response and remission in inpatients with depressive syndromes
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    J Affect Disord 133:137-49. 2011
    ..We aimed at detecting a set of clinical baseline variables for prediction of response and remission in 1014 naturalistically treated inpatients with major depressive episode treated for 53.62 ± 47.5 days...
  17. ncbi request reprint Self-reported data from patients with bipolar disorder: frequency of brief depression
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany
    J Affect Disord 101:227-33. 2007
    ..Using daily self-reported mood ratings, we studied how changing the length requirement to that typical of recurrent brief depression (2-4 days) would impact the number of depressed episodes...
  18. doi request reprint Influence of atypical features on the quality of prophylactic effectiveness of long-term lithium treatment in bipolar disorders
    Andrea Pfennig
    Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universitat Dresden, Dresden, Germany
    Bipolar Disord 12:390-6. 2010
    ....
  19. doi request reprint Algorithm-guided treatment of depression reduces treatment costs--results from the randomized controlled German Algorithm Project (GAPII)
    Roland Ricken
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Germany
    J Affect Disord 134:249-56. 2011
    ..The objective of this study was a health economic evaluation of SSTR based on a cost effectiveness analysis (CEA)...
  20. ncbi request reprint Altered representation of expected value in the orbitofrontal cortex in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Hum Brain Mapp 31:958-69. 2010
    ..Here we studied neural correlates of gain and loss expectation in mania using functional magnetic resonance imaging (fMRI)...
  21. ncbi request reprint Using ultrasonography to determine thyroid size and prevalence of goiter in lithium-treated patients with affective disorders
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    J Affect Disord 104:45-51. 2007
    ..To determine thyroid gland volume and the prevalence of goiter in patients receiving long-term lithium treatment for affective disorders...
  22. ncbi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and continuation treatment of major depressive disorder
    Michael Bauer
    Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles ULCA, 300 UCLA Medical Plaza, Suite 2330, Los Angeles, CA 90095, USA
    World J Biol Psychiatry 3:5-43. 2002
    ....
  23. doi request reprint Relationship among latitude, climate, season and self-reported mood in bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany Fetscherstr 74, 01307 Dresden, Germany
    J Affect Disord 116:152-7. 2009
    ..We also investigated the influence of latitude and seasonal climate variables on mood...
  24. doi request reprint Self-reporting software for bipolar disorder: validation of ChronoRecord by patients with mania
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Psychiatry Res 159:359-66. 2008
    ..Post-hoc analysis of the level of agreement between ChronoRecord and YMRS ratings was excellent or good in all cases using the kappa statistic. These data demonstrate concurrent validity between ChronoRecord and YMRS...
  25. doi request reprint Do efficacy and effectiveness samples differ in antidepressant treatment outcome? An analysis of eligibility criteria in randomized controlled trials
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University Munich, Munich, Germany
    J Clin Psychiatry 71:1425-33. 2010
    ..Because of strict inclusion and exclusion criteria, results drawn from placebo-controlled randomized antidepressant efficacy trials may not be transferable to real-world patients...
  26. doi request reprint The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Hum Psychopharmacol 25:47-54. 2010
    ..This study investigated whether the daily number of psychotropic medications or the daily number of pills were associated with self-reported adherence with taking a mood stabilizer...
  27. doi request reprint Brief depressive symptoms in patients with bipolar disorder: analysis of long-term self-reported data
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany
    Aust N Z J Psychiatry 46:1068-78. 2012
    ..This study explores the frequency of brief depressive episodes, lasting 1 to 4 days, using daily self-reported mood ratings...
  28. doi request reprint Long-term outcome after lithium augmentation in unipolar depression: focus on HPA system activity
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Neuropsychobiology 60:23-30. 2009
    ....
  29. doi request reprint Regional cerebral glucose metabolism and anxiety symptoms in bipolar depression: effects of levothyroxine
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Psychiatry Res 181:71-6. 2010
    ..Results indicate that comorbid anxiety symptoms have specific regional cerebral metabolic correlates in bipolar depression and cannot only be explained exclusively by the depressive state of the patients...
  30. doi request reprint Association between age of onset and mood in bipolar disorder: comparison of subgroups identified by cluster analysis and clinical observation
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstr 74 01307 Dresden, Germany
    J Psychiatr Res 44:1170-5. 2010
    ..This study compared subgroups identified by cluster analysis and clinical observation by evaluating the association between the age of onset of bipolar disorder and self-reported daily mood ratings...
  31. ncbi request reprint Supraphysiologic doses of levothyroxine as adjunctive therapy in bipolar depression: a randomized, double-blind, placebo-controlled study
    Thomas J Stamm
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin
    J Clin Psychiatry 75:162-8. 2014
    ..This study tested the efficacy of adjunctive treatment with supraphysiologic doses of levothyroxine in patients with bipolar depression and the hypothesis that women would display a better outcome compared to men...
  32. doi request reprint Executive summary of the report by the WPA section on pharmacopsychiatry on general and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders
    Thomas C Baghai
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Nußbaumstraße 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 262:13-22. 2012
    ..A modern individualized antidepressant treatment in most cases is a well-tolerated and efficacious tool to minimize the negative impact of the otherwise devastating and life-threatening outcome of depressive disorders...
  33. doi request reprint Comparison of sleep/wake parameters for self-monitoring bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    J Affect Disord 116:170-5. 2009
    ..This analysis further investigated whether sleep duration, sleep onset or sleep offset was the most useful sleep/wake parameter to monitor for an oncoming mood change...
  34. pmc Decreasing the minimum length criterion for an episode of hypomania: evaluation using self-reported data from patients with bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany
    Eur Arch Psychiatry Clin Neurosci 261:341-7. 2011
    ..Frequency may be an important dimensional aspect of brief hypomania. Clinicians should regularly probe for brief hypomania...
  35. doi request reprint The controversial link between antidepressants and suicidality risks in adults: data from a naturalistic study on a large sample of in-patients with a major depressive episode
    Florian Seemüller
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Germany
    Int J Neuropsychopharmacol 12:181-9. 2009
    ..g. use of specific co-medications, supportive psychotherapy and continuous medical attendance by nursing staff) might be beneficial...
  36. ncbi request reprint Lithium's emerging role in the treatment of refractory major depressive episodes: augmentation of antidepressants
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Neuropsychobiology 62:36-42. 2010
    ..Therefore, there is a critical need for effective medication strategies that augment treatment with antidepressants...
  37. doi request reprint Response and remission criteria in major depression--a validation of current practice
    Michael Riedel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    J Psychiatr Res 44:1063-8. 2010
    ..91) and a decrease of 47% for the BDI baseline score (AUC: 0.78) best corresponded CGI response criteria. Our data largely confirmed currently used remission and response criteria in naturalistically treated patients...
  38. doi request reprint Prescribing patterns of antidepressants in Europe: results from the Factors Influencing Depression Endpoints Research (FINDER) study
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Eur Psychiatry 23:66-73. 2008
    ..In conclusion, the prescribing of antidepressants varies by country, and the type of antidepressant chosen is influenced by physician- as well as patient-related factors...
  39. doi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for biological treatment of unipolar depressive disorders, part 1: update 2013 on the acute and continuation treatment of unipolar depressive disorders
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universitat Dresden, Dresden, Germany
    World J Biol Psychiatry 14:334-85. 2013
    ..The guidelines are intended for use by all physicians seeing and treating patients with these conditions...
  40. ncbi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders in Primary Care
    Michael Bauer
    University Hospital Carl Gustav Carus, Department of Psychiatry and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    World J Biol Psychiatry 8:67-104. 2007
    ..They deal primarily with biological treatment (including antidepressants, other psychopharmacological and hormonal medications, electroconvulsive therapy, light therapy)...
  41. doi request reprint Context insensitivity during positive and negative emotional expectancy in depression assessed with functional magnetic resonance imaging
    Melanie Feeser
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Chariteplatz 1, 10117 Berlin, Germany
    Psychiatry Res 212:28-35. 2013
    ..This hyporeactivity may contribute to clinical features like anergia, apathy, and loss of motivation in the context of both positive and negative incentives...
  42. doi request reprint Serotonin transporter gene and response to lithium augmentation in depression
    Thomas J Stamm
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Psychiatr Genet 18:92-7. 2008
    ..Lithium augmentation is a well-established strategy for overcoming treatment resistance. In this study, the 5-HTTLPR allele variant's effect on lithium augmentation was analyzed in antidepressant-nonresponsive patients...
  43. doi request reprint Rapid cycling bipolar disorder--diagnostic concepts
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Bipolar Disord 10:153-62. 2008
    ..This paper reviews the literature to examine the DSM-IV diagnostic criteria for rapid cycling in bipolar disorder...
  44. doi request reprint Prevalence and treatment outcome in anxious versus nonanxious depression: results from the German Algorithm Project
    Katja Wiethoff
    Charite Universitatsmedizin Berlin, Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Berlin, Germany
    J Clin Psychiatry 71:1047-54. 2010
    ..Furthermore, the efficacy of algorithm-guided treatment versus treatment as usual in patients with anxious versus nonanxious depression was evaluated...
  45. doi request reprint Association between median family income and self-reported mood symptoms in bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Fetscherstr 74, 01307 Dresden, Germany
    Compr Psychiatry 52:17-25. 2011
    ..This study investigated the relation between median family income and self-reported mood symptoms in patients with bipolar disorder who reside in the United States...
  46. ncbi request reprint Relationship between adjunctive medications for anxiety and time spent ill in patients with bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Germany
    Int J Psychiatry Clin Pract 13:70-7. 2009
    ..While this methodology cannot determine causality, these findings highlight the need for controlled studies of the long-term impact of adjunctive medications for anxiety on mood symptoms in patients being treated for bipolar disorder. ..
  47. ncbi request reprint Effects of supraphysiological thyroxine administration in healthy controls and patients with depressive disorders
    Michael Bauer
    Department of Psychiatry, Klinikum Benjamin Franklin, Freie Universitat Berlin, Berlin, Germany
    J Affect Disord 68:285-94. 2002
    ..Unexpectedly, only minimal side effects have been reported. The goal of the present study was to investigate whether healthy controls and depressed patients differ in their ability to tolerate supraphysiological doses of T(4)...
  48. doi request reprint Functional neuroanatomy of emotion processing in major depressive disorder is altered after successful antidepressant therapy
    Gabriela Rosenblau
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:1424-33. 2012
    ..These findings show that the neural mechanisms of emotion anticipation and processing are altered in patients with MDD and that these alterations are able to normalize after treatment with an antidepressant...
  49. ncbi request reprint Response to lithium augmentation in depression is associated with the glycogen synthase kinase 3-beta -50T/C single nucleotide polymorphism
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Biol Psychiatry 62:1295-302. 2007
    ..This study investigates the association of the GSK3B -50T/C SNP and response to lithium augmentation in acutely depressed antidepressant nonresponders...
  50. doi request reprint Subsyndromal mood symptoms: a useful concept for maintenance studies of bipolar disorder?
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Psychopathology 43:1-7. 2010
    ..To explore the measurement of subsyndromal mood symptoms in relation to studies of maintenance therapy for bipolar disorder...
  51. pmc Does the use of an automated tool for self-reporting mood by patients with bipolar disorder bias the collected data?
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Germany
    MedGenMed 7:21. 2005
    ..Automating data collection from patients can improve data quality, enhance compliance, and decrease costs in longitudinal studies. About half of all households in industrialized countries now have a home computer...
  52. ncbi request reprint Prophylaxis of schizoaffective disorder with lithium or carbamazepine: outcome after long-term follow-up
    Christopher Baethge
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Benjamin Franklin, Freie Universitat Berlin, Eschenallee 3, 14050 Berlin, Germany
    J Affect Disord 79:43-50. 2004
    ....
  53. doi request reprint Reduced body mass index in Parkinson's disease: contribution of comorbid depression
    Maximilian Pilhatsch
    Department of Psychiatry and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    J Nerv Ment Dis 201:76-9. 2013
    ..3; Hedges' g) but not in female PD patients. Although some possible confounders are not controlled here, our results support the need of monitoring depressive symptoms in the courses of PD, particularly in male patients...
  54. doi request reprint Hyporeactivity of ventral striatum towards incentive stimuli in unmedicated depressed patients normalizes after treatment with escitalopram
    Meline Stoy
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Psychopharmacol 26:677-88. 2012
    ..These findings suggest that MDD patients show ventral striatal hyporesponsiveness during incentive cue processing, which normalizes after successful treatment...
  55. doi request reprint Long-term treatment with supraphysiological doses of thyroid hormone in affective disorders - effects on bone mineral density
    Roland Ricken
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    J Affect Disord 136:e89-94. 2012
    ..To investigate the long-term effects of supraphysiological, TSH suppressive doses of levothyroxine (TSDL) on bone mineral density (BMD) in patients with affective disorders during an average treatment duration of 69 months...
  56. ncbi request reprint Extended-release quetiapine fumarate (quetiapine XR) monotherapy and quetiapine XR or lithium as add-on to antidepressants in patients with treatment-resistant major depressive disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstr 74, D 01307 Dresden, Germany
    J Affect Disord 151:209-19. 2013
    ..Patients with treatment-resistant major depressive disorder (MDD) remain a common clinical challenge...
  57. pmc The diagnosis and treatment of bipolar disorder: recommendations from the current s3 guideline
    Andrea Pfennig
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    Dtsch Arztebl Int 110:92-100. 2013
    ..Bipolar disorder is a serious mental illness, characterized by frequent recurrences and major comorbidities. Its consequences can include suicide...
  58. ncbi request reprint Effectiveness and feasibility of a standardized stepwise drug treatment regimen algorithm for inpatients with depressive disorders: results of a 2-year observational algorithm study
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Universitatsklinikum Charite, Humboldt Universitat zu Berlin, Germany
    J Clin Psychiatry 63:782-90. 2002
    ..We are reporting on the first of 3 subsequent study phases evaluating effectiveness and feasibility of the SSTR in a naturalistic clinical setting...
  59. pmc Efficacy of a systematic depression management program in high utilizers of primary care: a randomized trial
    Anne Berghöfer
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    BMC Health Serv Res 12:298. 2012
    ..This study aims to examine the effects of a systematic screening and collaborative treatment program on depression severity in small primary care practices of the German outpatient health care system...
  60. doi request reprint Treatment options for acute depression in bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universitat Dresden, Dresden, Germany
    Bipolar Disord 14:37-50. 2012
    ..The purpose of this manuscript is to review the evidence base of the available treatment options for bipolar depression within two frequent clinical scenarios...
  61. ncbi request reprint Is dose escalation of antidepressants a rational strategy after a medium-dose treatment has failed? A systematic review
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Germany
    Eur Arch Psychiatry Clin Neurosci 255:387-400. 2005
    ..e. augmentation or change of compound) are lacking. The aim of this publication is to review available direct and indirect evidence concerning dose increase of antidepressants after a medium-dose trial has failed...
  62. ncbi request reprint World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 2: Maintenance treatment of major depressive disorder and treatment of chronic depressive disorders and subthreshold
    Michael Bauer
    University of California Los Angeles UCLA, Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, Los Angeles, CA, USA
    World J Biol Psychiatry 3:69-86. 2002
    ....
  63. ncbi request reprint Awareness of metabolic concerns in patients with bipolar disorder: a survey of European psychiatrists
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, D 01307 Dresden, Germany
    Eur Psychiatry 23:169-77. 2008
    ..An online survey of European psychiatrists assessed awareness of the metabolic syndrome and its influence on the management of bipolar disorder...
  64. ncbi request reprint Lithium augmentation increases post-dexamethasone cortisol in the dexamethasone suppression test in unipolar major depression
    Tom Bschor
    Department of Psychiatry, Technische Universitat Dresden, Germany
    Depress Anxiety 17:43-8. 2003
    ..This is in contrast to the established decline of HPA system activity during treatment with tricyclic antidepressants...
  65. ncbi request reprint Hypothalamic-pituitary-end organ function in women with bipolar depression
    Natalie L Rasgon
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, CA 94305 5723, USA
    Psychoneuroendocrinology 32:279-86. 2007
    ..The results are preliminary, and require replication in larger samples...
  66. ncbi request reprint Longitudinal evaluation of reproductive function in women treated for bipolar disorder
    Natalie L Rasgon
    Department of Psychiatry and Behavioral Sciences, Stanford School of Medicine, Stanford University, 401 Quarry Road, Palo Alto, Ca 94305 5723 Stanford, California, United States
    J Affect Disord 89:217-25. 2005
    ..We assessed reproductive endocrine and metabolic markers in women treated for bipolar disorder over a 2-year time period, controlling for valproate use...
  67. ncbi request reprint Approximate entropy of self-reported mood prior to episodes in bipolar disorder
    Tasha Glenn
    ChronoRecord Association, Inc, Fullerton, CA 92834, USA
    Bipolar Disord 8:424-9. 2006
    ....
  68. doi request reprint Risk constellations prior to the development of bipolar disorders: rationale of a new risk assessment tool
    Karolina Leopold
    Department of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universitat Dresden, Germany
    J Affect Disord 136:1000-10. 2012
    ..In the absence of well defined and disease specific biological markers for bipolar disorder, the recognition of premature stages must rely on combinations of risk factors that have been associated with later disease manifestation...
  69. ncbi request reprint Thyroid hormone and mood modulation: new insights from functional brain imaging techniques
    Michael Bauer
    Department of Psychiatry and Behavioral Sciences, Neuropsychiatric Institute and Hospital, University of California at Los Angeles, 760 Westwood Plaza, Los Angeles, CA 90024, USA
    Curr Psychiatry Rep 5:163-5. 2003
  70. doi request reprint A preliminary study of increased amygdala activation to positive affective stimuli in mania
    Felix Bermpohl
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Berlin, Germany
    Bipolar Disord 11:70-5. 2009
    ..The present study in hypomanic and manic patients explored how amygdala responses to affective stimuli depend on the valence of the stimuli presented...
  71. ncbi request reprint Early recognition of bipolar disorder
    Marta Hauser
    Early Recognition Center of Beginning Psychoses, Department of Psychiatry, Charite, Campus Mitte, Berlin, Germany
    Eur Psychiatry 22:92-8. 2007
    ..This will require prospective studies to determine the predictive power of the risk factors integrated into the scale...
  72. ncbi request reprint Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials
    Nicolas Andres Crossley
    Department of Psychiatry and Psychotherapy, Charite University Medicine Berlin, Campus Charite Mitte, Berlin, Germany
    J Clin Psychiatry 68:935-40. 2007
    ..Outcomes investigated included response rates and depression scale rates...
  73. ncbi request reprint Thyroid hormone augmentation with levothyroxine in bipolar depression
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite, Humbo dt Univers ty Berlin, Germany
    Bipolar Disord 4:109-10. 2002
  74. ncbi request reprint Lithium augmentation in treatment-resistant depression: clinical evidence, serotonergic and endocrine mechanisms
    T Bschor
    Department of Psychiatry and Psychotherapy, Technische Universitat Dresden, Dresden, Germany
    Pharmacopsychiatry 36:S230-4. 2003
    ..Here we review new data on the efficacy and mechanism of action of lithium augmentation...
  75. pmc Hypothalamic-pituitary-thyroid system activity during lithium augmentation therapy in patients with unipolar major depression
    Tom Bschor
    Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
    J Psychiatry Neurosci 28:210-6. 2003
    ..This study aimed at exploring the role of thyroid function in lithium augmentation and used a prospective design that included a homogeneous sample of inpatients with unipolar major depressive disorder...
  76. ncbi request reprint How long should the lithium augmentation strategy be maintained? A 1-year follow-up of a placebo-controlled study in unipolar refractory major depression
    Tom Bschor
    Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
    J Clin Psychopharmacol 22:427-30. 2002
    ..Study data suggest that active medication should be maintained for at least 1 year after successful lithium augmentation in patients with unipolar major depressive disorder...
  77. ncbi request reprint Long-term combination therapy versus monotherapy with lithium and carbamazepine in 46 bipolar I patients
    Christopher Baethge
    Department of Psychiatry, Harvard Medical School, McLean Division of Massachusetts General Hospital, Belmont, MA 02478, USA
    J Clin Psychiatry 66:174-82. 2005
    ..These trials suggest added benefit of combination treatment over use of either agent alone but also indicate the need for further studies...
  78. ncbi request reprint Association between response to lithium augmentation and the combined DEX/CRH test in major depressive disorder
    Tom Bschor
    Department of Psychiatry, Technische Universitat Dresden, Fetscherstrasse 74, D 01307, Dresden, Germany
    J Psychiatr Res 37:135-43. 2003
    ..Results of this study should be confirmed in a larger study group...
  79. ncbi request reprint Glucose utilization in the medial prefrontal cortex correlates with serotonin turnover rate and clinical depression in alcoholics
    Wendol Williams
    National Institute of Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD, USA
    Psychiatry Res 132:219-24. 2004
    ..This pilot study indicates that a dysfunction of medial PFC may interact with central serotonin turnover and negative mood states during early abstinence...
  80. pmc Impact of sunlight on the age of onset of bipolar disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Germany
    Bipolar Disord 14:654-63. 2012
    ..This study examined the association between the age of onset and sunlight at the location of onset...
  81. doi request reprint General and comparative efficacy and effectiveness of antidepressants in the acute treatment of depressive disorders: a report by the WPA section of pharmacopsychiatry
    Thomas C Baghai
    Department of Psychiatry and Psychotherapy, Ludwig Maximilian University of Munich, Nussbaumstrasse 7, 80336, Munich, Germany
    Eur Arch Psychiatry Clin Neurosci 261:207-45. 2011
    ..Modern individualized antidepressant treatment is in most cases a well-tolerated and efficacious approach to minimize the negative impact of otherwise potentially devastating and life-threatening outcomes in depressive disorders...
  82. doi request reprint Does early improvement triggered by antidepressants predict response/remission? Analysis of data from a naturalistic study on a large sample of inpatients with major depression
    Verena Henkel
    Department of Psychiatry and Psychotherapy, Ludwig Maximilians University Munich, Nussbaumstrasse 7, 80336 Munich, Germany
    J Affect Disord 115:439-49. 2009
    ..Patients were treated with various antidepressants and co-medication according to the protocol based on evidence-based clinical guidelines...
  83. ncbi request reprint Duloxetine: a new selective and dual-acting antidepressant
    Michael Bauer
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Schumannstrasse 20 21, D 10117 Berlin, Germany
    Expert Opin Pharmacother 7:421-7. 2006
    ..Therefore, duloxetine provides an alternative to current therapeutic options in the treatment of the different symptoms of depression...
  84. ncbi request reprint Efficacy and mechanisms of action of lithium augmentation in refractory major depression
    Tom Bschor
    Department of Psychiatry and Psychotherapy, Jewish Hospital Berlin, Heinz Galinski Str 1, D 13347 Berlin, Germany
    Curr Pharm Des 12:2985-92. 2006
    ..In international treatment guidelines and algorithms, lithium augmentation is considered a first-line treatment strategy for patients with a major depressive episode who do not adequately respond to standard antidepressant treatment...
  85. ncbi request reprint Extended-release quetiapine as adjunct to an antidepressant in patients with major depressive disorder: results of a randomized, placebo-controlled, double-blind study
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    J Clin Psychiatry 70:540-9. 2009
    ..This 6-week, randomized, double-blind study evaluated efficacy and safety of adjunctive extended-release (XR) quetiapine in patients with major depressive disorder (MDD) and an inadequate response to >or= 1 antidepressant...
  86. ncbi request reprint Pharmacogenetics of antidepressants and antipsychotics: the contribution of allelic variations to the phenotype of drug response
    J Kirchheiner
    Institute of Clinical Pharmacology, Campus Charite Mitte, University Medicine Berlin, Berlin, Germany
    Mol Psychiatry 9:442-73. 2004
    ....
  87. ncbi request reprint Factors influencing depression endpoints research (FINDER): study design and population characteristics
    Ana Garcia-Cebrian
    Eli Lilly and Company Limited, Lilly Research Centre, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH, UK
    Eur Psychiatry 23:57-65. 2008
    ..Further investigation into factors associated with HRQoL in depression after treatment initiation is warranted...
  88. ncbi request reprint Is successful lithium augmentation limited to serotonergic antidepressants?
    Tom Bschor
    J Clin Psychopharmacol 24:240-1; author reply 241-2. 2004
  89. ncbi request reprint Prophylaxis latency and outcome in bipolar disorders
    Christopher Baethge
    Consolidated Department of Psychiatry, Harvard Medical School, Bipolar and Psychotic Disorders Program, McLean Division of Massachusetts General Hospital, Belmont, Massachusetts, USA
    Can J Psychiatry 48:449-57. 2003
    ..To analyze new and reviewed findings to evaluate relations between treatment response and latency from onset of bipolar disorder (BD) to the start of mood-stabilizer prophylaxis...
  90. ncbi request reprint Lithium augmentation increases the ACTH and cortisol response in the combined DEX/CRH test in unipolar major depression
    Tom Bschor
    Department of Psychiatry, Technische Universitat Dresden, Dresden, Germany
    Neuropsychopharmacology 27:470-8. 2002
    ..This effect might be explained by the serotonergic effects of lithium...
  91. doi request reprint A pooled analysis of two randomised, placebo-controlled studies of extended release quetiapine fumarate adjunctive to antidepressant therapy in patients with major depressive disorder
    Michael Bauer
    Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
    J Affect Disord 127:19-30. 2010
    ..Additional post hoc analyses examined the efficacy of quetiapine XR against specific depressive symptoms including sleep...
  92. ncbi request reprint Menstrual cycle related mood changes in women with bipolar disorder
    Natalie Rasgon
    Department of Psychiatry and Biobehavioral Sciences, Neuropsychiatric Institute and Hospital, University of California Los Angeles, CA, USA
    Bipolar Disord 5:48-52. 2003
    ..This study investigates the influence of the menstrual cycle on mood in women with BPD who are taking medication, but not selected for menstrual abnormalities...
  93. ncbi request reprint Effects of acute psychological stress on adhesion molecules, interleukins and sex hormones: implications for coronary heart disease
    Andreas Heinz
    Department of Psychiatry of the Charité, Humboldt University of Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Psychopharmacology (Berl) 165:111-7. 2003
    ..Cell adhesion molecules may be activated by psychological stress exposure, depending on their interaction with the interleukin network, sex hormones and cortisol secretion...
  94. doi request reprint Novelty seeking modulates medial prefrontal activity during the anticipation of emotional stimuli
    Felix Bermpohl
    Berenson Allen Center for Non Invasive Brain Stimulation, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Psychiatry Res 164:81-5. 2008
    ..BOLD responses to emotional expectancy were positively correlated with novelty-seeking scores in the medial prefrontal cortex. This correlation was strongest for the sub-dimension of exploratory excitability...
  95. ncbi request reprint Algorithms and collaborative-care systems for depression: are they effective and why? A systematic review
    Mazda Adli
    Department of Psychiatry and Psychotherapy, Charite Universitatsmedizin Berlin, Campus Charite Mitte, Berlin, Germany
    Biol Psychiatry 59:1029-38. 2006
    ....
  96. doi request reprint Connective tissue growth factor expression is increased in collagenous colitis and coeliac disease
    Ute Gunther
    Medical Clinic I Gastroenterology, Infectious Diseases, Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
    Histopathology 57:427-35. 2010
    ..The aim of this study was to investigate CTGF expression by in situ hybridization (ISH) and polymerase chain reaction (PCR) in CC and coeliac disease as well as lymphocytic colitis (LC), Crohn's colitis and ulcerative colitis (UC)...
  97. ncbi request reprint Long-term effectiveness of lithium in bipolar disorder: a multicenter investigation of patients with typical and atypical features
    Anne Berghöfer
    Institute for Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, 10098 Berlin, Germany
    J Clin Psychiatry 69:1860-8. 2008
    ..The purpose of this study was to investigate the influence of atypical symptoms on the effectiveness and stability of long-term lithium treatment in a prospective, multicenter cohort of bipolar patients in a naturalistic setting...
  98. ncbi request reprint Reward anticipation and outcomes in adult males with attention-deficit/hyperactivity disorder
    Andreas Strohle
    Department of Psychiatry and Psychotherapy, Campus Charite Mitte, Charite Universitatsmedizin Berlin, Schumannstr 20 21, 10117 Berlin, Germany
    Neuroimage 39:966-72. 2008
    ..These findings suggest that male adults with ADHD show neural signs of abnormal reward processing. Future studies will have to investigate whether these dysfunctional patterns might be normalized by treatment...
  99. ncbi request reprint Individualized medicine - implementation of pharmacogenetic diagnostics in antidepressant drug treatment of major depressive disorders
    J Kirchheiner
    Institute of Clinical Pharmacology, Charite University Medicine Berlin, Campus Charité Mitte CCM, Berlin, Germany
    Pharmacopsychiatry 36:S235-43. 2003
    ....
  100. doi request reprint Genes and neuroimaging: advances in psychiatric research
    J Gallinat
    Klinik fur Psychiatrie und Psychotherapie, Charite Universitatsmedizin Berlin, Campus Mitte, Berlin, Germany
    Neurodegener Dis 5:277-85. 2008
    ..Furthermore, recently identified putative susceptibility genes for schizophrenia (neuregulin 1, dysbindin, G72) are briefly discussed...
  101. ncbi request reprint Double-blind, placebo-controlled trial of the use of lithium to augment antidepressant medication in continuation treatment of unipolar major depression
    M Bauer
    Neuropsychiatric Institute and Hospital, Department of Psychiatry and Biobehavioral Sciences, University of California at Los Angeles, 90095 6968, USA
    Am J Psychiatry 157:1429-35. 2000
    ..The authors examined the efficacy of lithium augmentation in the continuation treatment of unipolar major depressive disorder...