Chalif Assaf

Summary

Affiliation: Humboldt University
Country: Germany

Publications

  1. ncbi Drug evaluation: zanolimumab, a human monoclonal antibody targeted against CD4
    Chalid Assaf
    Skin Cancer Center Charite, Department of Dermatology, Venereology and Allergy, Charite Universitatsmedizin Berlin, Fabeckstr 60 62, 14195 Berlin, Germany
    Curr Opin Mol Ther 9:197-203. 2007
  2. ncbi Absence of microsatellite instability and lack of evidence for subclone diversification in the pathogenesis and progression of mycosis fungoides
    Chalid Assaf
    Department of Dermatology and Allergy, Skin Cancer Center Charite, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Invest Dermatol 127:1752-61. 2007
  3. ncbi Cutaneous lymphomas in Germany: an analysis of the Central Cutaneous Lymphoma Registry of the German Society of Dermatology (DDG)
    Chalid Assaf
    Department of Dermatology, Allergy and Venereology, Skin Tumor Center Charité HTCC, Charite University Medicine, Berlin, Germany
    J Dtsch Dermatol Ges 5:662-8. 2007
  4. ncbi CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer
    Chalid Assaf
    Department of Dermatology, Charite, Berlin, Germany
    J Clin Pathol 60:981-9. 2007
  5. ncbi Minimizing adverse side-effects of oral bexarotene in cutaneous T-cell lymphoma: an expert opinion
    C Assaf
    Department of Dermatology and Allergy, Skin Cancer Center Charite, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Br J Dermatol 155:261-6. 2006
  6. ncbi Classification of primary cutaneous lymphomas
    Chalid Assaf
    Department of Dermatology, , Berlin, Germany
    Front Radiat Ther Oncol 39:25-37. 2006
  7. ncbi The clinical impact of T cell receptor rearrangement analysis in cutaneous T cell lymphoma
    Chalid Assaf
    Department of Dermatology, , Berlin, Germany
    Front Radiat Ther Oncol 39:16-24. 2006
  8. ncbi [Therapy of cutaneous T-cell lymphoma]
    Chalif Assaf
    Hauttumorcentrum Charit, , Allergologie und Venerologie, , Fabeckstr 60-62D-14195 Berlin
    J Dtsch Dermatol Ges 6:256-8. 2008
  9. ncbi Relapse of primary extranodal marginal-zone B-cell lymphoma of the dura mater
    Chalid Assaf
    Department of Dermatology, , Campus Benjamin Franklin, Berlin, Germany
    Lancet Oncol 6:187-9. 2005
  10. ncbi Transition of Sézary syndrome into mycosis fungoides after complete clinical and molecular remission under extracorporeal photophoresis
    C Assaf
    Department of Dermatology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Fabeckstrasse 60 62, 14195 Berlin, Germany
    J Clin Pathol 57:1325-8. 2004

Detail Information

Publications20

  1. ncbi Drug evaluation: zanolimumab, a human monoclonal antibody targeted against CD4
    Chalid Assaf
    Skin Cancer Center Charite, Department of Dermatology, Venereology and Allergy, Charite Universitatsmedizin Berlin, Fabeckstr 60 62, 14195 Berlin, Germany
    Curr Opin Mol Ther 9:197-203. 2007
    ..Zanolimumab is currently undergoing phase III clinical trials for CTCL and phase II clinical trials for NCTCL...
  2. ncbi Absence of microsatellite instability and lack of evidence for subclone diversification in the pathogenesis and progression of mycosis fungoides
    Chalid Assaf
    Department of Dermatology and Allergy, Skin Cancer Center Charite, Charite Universitatsmedizin Berlin, Berlin, Germany
    J Invest Dermatol 127:1752-61. 2007
    ..These results suggest that progressive accumulation of mutations as detected by MS analysis does not play a major role in the pathogenesis or in the progression of mycosis fungoides...
  3. ncbi Cutaneous lymphomas in Germany: an analysis of the Central Cutaneous Lymphoma Registry of the German Society of Dermatology (DDG)
    Chalid Assaf
    Department of Dermatology, Allergy and Venereology, Skin Tumor Center Charité HTCC, Charite University Medicine, Berlin, Germany
    J Dtsch Dermatol Ges 5:662-8. 2007
    ..The epidemiology of cutaneous lymphomas in Germany is compared to other national or regional lymphoma registries...
  4. ncbi CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer
    Chalid Assaf
    Department of Dermatology, Charite, Berlin, Germany
    J Clin Pathol 60:981-9. 2007
    ..However, prognostic subsets within the CD56+ group have been difficult to identify due to the lack of uniform clinicopathological and immunophenotypical criteria...
  5. ncbi Minimizing adverse side-effects of oral bexarotene in cutaneous T-cell lymphoma: an expert opinion
    C Assaf
    Department of Dermatology and Allergy, Skin Cancer Center Charite, Charite Universitatsmedizin Berlin, Schumannstrasse 20 21, 10117 Berlin, Germany
    Br J Dermatol 155:261-6. 2006
    ..When further information becomes available on how bexarotene interacts with lipid metabolism and thyroid function, the management approach suggested here may need to be changed...
  6. ncbi Classification of primary cutaneous lymphomas
    Chalid Assaf
    Department of Dermatology, , Berlin, Germany
    Front Radiat Ther Oncol 39:25-37. 2006
  7. ncbi The clinical impact of T cell receptor rearrangement analysis in cutaneous T cell lymphoma
    Chalid Assaf
    Department of Dermatology, , Berlin, Germany
    Front Radiat Ther Oncol 39:16-24. 2006
  8. ncbi [Therapy of cutaneous T-cell lymphoma]
    Chalif Assaf
    Hauttumorcentrum Charit, , Allergologie und Venerologie, , Fabeckstr 60-62D-14195 Berlin
    J Dtsch Dermatol Ges 6:256-8. 2008
  9. ncbi Relapse of primary extranodal marginal-zone B-cell lymphoma of the dura mater
    Chalid Assaf
    Department of Dermatology, , Campus Benjamin Franklin, Berlin, Germany
    Lancet Oncol 6:187-9. 2005
  10. ncbi Transition of Sézary syndrome into mycosis fungoides after complete clinical and molecular remission under extracorporeal photophoresis
    C Assaf
    Department of Dermatology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Fabeckstrasse 60 62, 14195 Berlin, Germany
    J Clin Pathol 57:1325-8. 2004
    ..These findings indicate that the neoplastic cells in SS, MF, and LCL are derived from a common precursor T cell, despite the change in clinical phenotype...
  11. ncbi Early TCR-beta and TCR-gamma PCR detection of T-cell clonality indicates minimal tumor disease in lymph nodes of cutaneous T-cell lymphoma: diagnostic and prognostic implications
    Chalid Assaf
    Department of Dermatology, Charite University Medicine Berlin, Campus Benjamin Franklin, Berlin, Germany
    Blood 105:503-10. 2005
    ..Thus, T-cell clonality analysis is an important adjunct in differentiating benign dermatopathic lymphadenitis from early CTCL involvement...
  12. ncbi Denileukin diftitox therapy for patients with tumour-stage mycosis fungoides
    Chalid Assaf
    Department of Dermatology and Allergy Skin Cancer Center Charit, Berlin, Germany
    Dermatol Clin 26:21-2. 2008
  13. ncbi [cFLIP diminishes CD95-induced apoptosis of CD30-stimulated cutaneous anaplastic large T cell lymphoma (cALCL) cells]
    B Hirsch
    Institut fur Pathologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin
    Pathologe 31:193-8. 2010
    ..Knockdown of cFLIP restores sensitivity to CD95-mediated apoptosis. We conclude that the anti-apoptotic function of CD30 antibodies should be kept in mind if CD30 antibody-based therapeutic concepts for ALCL lymphoma are considered...
  14. ncbi Three coexisting lymphomas in one patient: genetically related or only a coincidence?
    M Steinhoff
    Department of Dermatology and Allergy, Charite Universitaetsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    J Clin Pathol 59:1312-5. 2006
    ..The simultaneous occurrence of three different, clonally unrelated lymphomas in one patient at the same time has not been reported yet...
  15. ncbi T-cell and T/natural killer-cell lymphomas involving ocular and ocular adnexal tissues: a clinicopathologic, immunohistochemical, and molecular study of seven cases
    S E Coupland
    Department of Pathology, University Hospital Benjamin Franklin, Berlin, Germany
    Ophthalmology 106:2109-20. 1999
    ..Lymphomas of the eye and its adnexa are frequently of B lineage. This study aims to characterize the clinical and histopathologic features of the rare non-B-cell non-Hodgkin lymphomas (NHL) of these locations...
  16. ncbi Overexpression of c-myb in leukaemic and non-leukaemic variants of cutaneous T-cell lymphoma
    N Poenitz
    Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Ruprecht Karl University of Heidelberg, Mannheim, Germany
    Dermatology 211:84-92. 2005
    ....
  17. ncbi Diagnostic tools in Sezary syndrome
    M Möbs
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitatsmedizin, Berlin, Germany
    G Ital Dermatol Venereol 145:385-91. 2010
    ..5 to 27 percent and estimated median survival of 14.5 to 18 months. The incidence of MF and also SS has increased with time and may be in part due to improved clinical awareness and especially advances in diagnostic testing...
  18. ncbi Cutaneous T cell lymphoma and classic Hodgkin lymphoma of the B cell type within a single lymph node: composite lymphoma
    M Steinhoff
    Department of Dermatology, University Medical Center Benjamin Franklin, The Free University of Berlin, Fabeckstrasse 60 62, 14195 Berlin, Germany
    J Clin Pathol 57:329-31. 2004
    ..This report describes the manifestation of a true composite lymphoma within a single cervical lymph node, which is composed of a cutaneous T cell lymphoma and a classic Hodgkin lymphoma of B cell type--a very rare finding indeed...
  19. ncbi The treatment of mycosis fungoides
    D Sebastian Mestel
    Department of Dermatology and Allergy, Skin Cancer Center, Charite Universitaetsmedizin, Berlin, Germany
    G Ital Dermatol Venereol 143:395-408. 2008
    ..The aim of this article was to present actual assumed treatment modalities, as well as new therapeutic strategies which passed already through clinical trials showing promising results in the treatment of PCLs...
  20. ncbi Sézary syndrome is a unique cutaneous T-cell lymphoma as identified by an expanded gene signature including diagnostic marker molecules CDO1 and DNM3
    N Booken
    Department of Dermatology, Venereology and Allergology, University Medical Centre Mannheim, Ruprecht Karl University of Heidelberg, Mannheim, Germany
    Leukemia 22:393-9. 2008
    ..Furthermore, CDO1 catalyzes taurine synthesis and taurine inhibits apoptosis and promotes chemoprotection. In summary, CDO1 and DNM3 may improve the diagnosis of SS and open novel clues to its pathogenesis...