Research Topics
| Kristina AllersSummaryAffiliation: Humboldt University Country: Germany Publications
| Collaborators
|
Detail Information
Publications
Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantationKristina Allers
Department of Gastroenterology, Infectious Diseases, and Rheumatology, Medical Clinic I, Campus Benjamin Franklin, Charite University Medicine Berlin, Berlin, Germany
Blood 117:2791-9. 2011..In conclusion, our results strongly suggest that cure of HIV has been achieved in this patient...
Migration patterns of nonspecifically activated versus nonactivated nonhuman primate T lymphocytes: preferential homing of activated autologous CD8+ T cells in the rectal mucosaKristina Allers
Medical Clinic I, Gastroenterology, Infectious Diseases and Rheumatology, Charite Campus Benjamin Franklin, Berlin, Germany
J Immunother 31:334-44. 2008..The migratory behavior of in vitro-expanded, autologously transferred T cells can, therefore, influence the clinical outcome of adoptive cell transfer...
Gut mucosal FOXP3+ regulatory CD4+ T cells and Nonregulatory CD4+ T cells are differentially affected by simian immunodeficiency virus infection in rhesus macaquesKristina Allers
Medical Clinic I Gastroenterology, Infectious Diseases and Rheumatology, Charite Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany
J Virol 84:3259-69. 2010..Although SIV production is limited in mucosal T(reg), T(reg) accumulation may indirectly contribute to viral persistence by suppressing antiviral immune responses...
Immunopathology of immune reconstitution inflammatory syndrome in Whipple's diseaseVerena Moos
Medizinische Klinik I, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, 12203 Berlin, Germany
J Immunol 190:2354-61. 2013....
Regulatory T cells in patients with Whipple's diseaseKatina Schinnerling
Medizinische Klinik I, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, D 12203 Berlin, Germany
J Immunol 187:4061-7. 2011..whipplei-infected macrophages are present. Thus, T(reg) might contribute to the chronic infection and systemic spread of T. whipplei in CWD but in contrast prevent mucosal barrier defect by reducing local inflammation...
Specific and nonspecific B-cell function in the small intestines of patients with Whipple's diseaseAnika Geelhaar
Medizinische Klinik I, Charite Universitatsmedizin Berlin, CBF, Berlin, Germany
Infect Immun 78:4589-92. 2010..However, this deficiency does not completely abolish T. whipplei-specific secretory IgA production that nonetheless does not protect from chronic infection...
Acute HIV infection induces mucosal infiltration with CD4+ and CD8+ T cells, epithelial apoptosis, and a mucosal barrier defectHans Jörg Epple
Medical Clinic I, Gastroenterology, Rheumatology, Infectiology, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, Berlin, Germany
Gastroenterology 139:1289-300. 2010..We analyzed T-cell subsets, epithelial apoptosis, and barrier function of the duodenal mucosa in patients with acute HIV infection...
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantationGero Hütter
Department of Hematology, Oncology, and Transfusion Medicine, Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Germany
N Engl J Med 360:692-8. 2009..The patient remained without viral rebound 20 months after transplantation and discontinuation of antiretroviral therapy. This outcome demonstrates the critical role CCR5 plays in maintaining HIV-1 infection...
Ion transport and barrier function are disturbed in microscopic colitisChristian Barmeyer
Department of Gastroenterology, Infectiology and Rheumatology, Charite, Campus Benjamin Franklin, Freie Universität and Humboldt Universität, Berlin, Germany
Ann N Y Acad Sci 1258:143-8. 2012..From a therapeutic perspective it can be postulated that the functional importance of loss of ions may be higher than that caused by barrier impairment...
Impaired immune functions of monocytes and macrophages in Whipple's diseaseVerena Moos
Medizinische Klinik I, Charite Universitatsmedizin Berlin, CBF, Berlin, Germany
Gastroenterology 138:210-20. 2010..However, macrophage activation in Whipple's disease has not been studied systematically so far...
Modulation of the CD4+ T-cell response by Helicobacter pylori depends on known virulence factors and bacterial cholesterol and cholesterol α-glucoside contentMacarena Beigier-Bompadre
Department of Molecular Biology, Max Planck Institute for Infection Biology, Berlin, Germany
J Infect Dis 204:1339-48. 2011..In conclusion, H. pylori shapes rather than suppresses human CD4(+) T-cell responses, and glucosylated cholesterol is a relevant bacterial component involved in this modulation...
