Andreas Holstein

Summary

Country: Germany

Publications

  1. ncbi request reprint Successful photo-and phenobarbital therapy during pregnancy in a woman with Crigler-Najjar syndrome type II
    Andreas Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Germany
    Scand J Gastroenterol 40:1124-6. 2005
  2. ncbi request reprint Severe hypoglycemia due to possible interaction between glibenclamide and sorafenib in a patient with hepatocellular carcinoma
    Andreas Holstein
    Lippe Detmold Hospital, First Department of Medicine, Röntgenstr 18, 32756 Detmold, Germany
    Curr Drug Saf 8:148-52. 2013
  3. doi request reprint CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects
    Andreas Holstein
    Lippe Detmold Hospital, First Department of Medicine, Röntgenstr 18, Detmold, 32756, Germany
    Expert Opin Drug Metab Toxicol 8:1549-63. 2012
  4. doi request reprint Number and sex ratio of children and impact of parental diabetes in individuals with Type 1 diabetes
    A Holstein
    Lippe Detmold Hospital, First Department of Medicine, Detmold, Germany
    Diabet Med 29:1268-71. 2012
  5. pmc Substantial increase in incidence of severe hypoglycemia between 1997-2000 and 2007-2010: a German longitudinal population-based study
    Andreas Holstein
    First Department of Medicine, Clinic Lippe Detmold, Detmold, Germany
    Diabetes Care 35:972-5. 2012
  6. pmc TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
    Andreas Holstein
    Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany
    BMC Med Genet 12:30. 2011
  7. ncbi request reprint [Traditional contraindications to the use of metformin -- more harmful than beneficial?]
    A Holstein
    Medizinische Klinik I, Klinikum Lippe Detmold, Detmold
    Dtsch Med Wochenschr 131:105-10. 2006
  8. ncbi request reprint Rheumatoid-like nodules in the spleen: new extraintestinal manifestation of Crohn's disease?
    Andreas Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    J Gastroenterol Hepatol 21:295-8. 2006
  9. ncbi request reprint Autoantibody profiles in microscopic colitis
    Andreas Holstein
    Department of Medicine I, Clinic Lippe Detmold, Röntgenstrasse 18, D 32756 Detmold, Germany
    J Gastroenterol Hepatol 21:1016-20. 2006
  10. doi request reprint Gemcitabine induced digital ischaemia and necrosis
    A Holstein
    1st Department of Medicine, Lippe Detmold Hospital, Detmold, Germany
    Eur J Cancer Care (Engl) 19:408-9. 2010

Detail Information

Publications33

  1. ncbi request reprint Successful photo-and phenobarbital therapy during pregnancy in a woman with Crigler-Najjar syndrome type II
    Andreas Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Germany
    Scand J Gastroenterol 40:1124-6. 2005
    ..This resulted in significantly reduced bilirubin levels in the mother, who gave birth to a healthy boy. A neonatal hyperbilirubinemia resolved spontaneously...
  2. ncbi request reprint Severe hypoglycemia due to possible interaction between glibenclamide and sorafenib in a patient with hepatocellular carcinoma
    Andreas Holstein
    Lippe Detmold Hospital, First Department of Medicine, Röntgenstr 18, 32756 Detmold, Germany
    Curr Drug Saf 8:148-52. 2013
    ..Profound blood glucose lowering effects of sorafenib might have additionally contributed to the hypoglycemic episode. ..
  3. doi request reprint CYP2C metabolism of oral antidiabetic drugs--impact on pharmacokinetics, drug interactions and pharmacogenetic aspects
    Andreas Holstein
    Lippe Detmold Hospital, First Department of Medicine, Röntgenstr 18, Detmold, 32756, Germany
    Expert Opin Drug Metab Toxicol 8:1549-63. 2012
    ..The cytochrome P4502C enzymes account for the metabolism of approximately 20% of therapeutic drugs including certain oral antidiabetic drugs (OADs)...
  4. doi request reprint Number and sex ratio of children and impact of parental diabetes in individuals with Type 1 diabetes
    A Holstein
    Lippe Detmold Hospital, First Department of Medicine, Detmold, Germany
    Diabet Med 29:1268-71. 2012
    ..To assess the number and sex ratio of children in individuals with Type 1 diabetes mellitus and the influence of parental diabetes on age at onset of Type 1 diabetes in our cohort...
  5. pmc Substantial increase in incidence of severe hypoglycemia between 1997-2000 and 2007-2010: a German longitudinal population-based study
    Andreas Holstein
    First Department of Medicine, Clinic Lippe Detmold, Detmold, Germany
    Diabetes Care 35:972-5. 2012
    ..To compare the incidences of severe hypoglycemia and corresponding clinical circumstances in a German population between 2007-2010 and 1997-2000...
  6. pmc TCF7L2 and therapeutic response to sulfonylureas in patients with type 2 diabetes
    Andreas Holstein
    Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany
    BMC Med Genet 12:30. 2011
    ..Since the association with diabetes could be explained by effects on insulin secretion, we investigated whether patients with diabetes risk alleles at rs7903146 might have an altered hypoglycaemic response to sulfonylureas (SUs)...
  7. ncbi request reprint [Traditional contraindications to the use of metformin -- more harmful than beneficial?]
    A Holstein
    Medizinische Klinik I, Klinikum Lippe Detmold, Detmold
    Dtsch Med Wochenschr 131:105-10. 2006
    ..It should be safe to withdraw metformin the evening before radiological examinations with intravenous contrast media or surgical procedures under general anaesthesia in diabetics with normal renal function...
  8. ncbi request reprint Rheumatoid-like nodules in the spleen: new extraintestinal manifestation of Crohn's disease?
    Andreas Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    J Gastroenterol Hepatol 21:295-8. 2006
    ..Abdominal lymphadenopathy is no longer present and the liver lesions are regressing. The intermittent course and the positive response to immunosuppressive therapy point to a further extraintestinal manifestation of Crohn's disease...
  9. ncbi request reprint Autoantibody profiles in microscopic colitis
    Andreas Holstein
    Department of Medicine I, Clinic Lippe Detmold, Röntgenstrasse 18, D 32756 Detmold, Germany
    J Gastroenterol Hepatol 21:1016-20. 2006
    ..We conducted a multicentre cross-sectional study to compare the antibody profiles of patients with collagenous and lymphocytic colitis with those of a control group...
  10. doi request reprint Gemcitabine induced digital ischaemia and necrosis
    A Holstein
    1st Department of Medicine, Lippe Detmold Hospital, Detmold, Germany
    Eur J Cancer Care (Engl) 19:408-9. 2010
    ..Digital amputation could be avoided. Acral ischemia is a rare but probably underreported adverse effect of gemcitabine therapy and a potential source of misdiagnosis...
  11. ncbi request reprint Oral antidiabetic drug metabolism: pharmacogenomics and drug interactions
    Andreas Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Röntgenstr 18, D 32756 Detmold, Germany
    Expert Opin Drug Metab Toxicol 5:225-41. 2009
    ..Thus, drug-drug interactions may substantially contribute to harmful effects of intensive glucose lowering therapy...
  12. doi request reprint Impact of clinical factors and CYP2C9 variants for the risk of severe sulfonylurea-induced hypoglycemia
    Andreas Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Röntgenstr 18, 32756 Detmold, Germany
    Eur J Clin Pharmacol 67:471-6. 2011
    ....
  13. doi request reprint Severe sulfonylurea-induced hypoglycemia: a problem of uncritical prescription and deficiencies of diabetes care in geriatric patients
    Andreas Holstein
    Lippe Detmold Clinic, First Department of Medicine, Röntgenstr 18, D 32756 Detmold, Germany
    Expert Opin Drug Saf 9:675-81. 2010
    ..We investigated the incidence of SH and clinical characteristics of patients with type 2 diabetes mellitus (T2DM) to demonstrate typical risk constellations...
  14. ncbi request reprint Hormonal counterregulation during severe hypoglycaemia under everyday conditions in patients with type 1 and insulin-treated type 2 diabetes mellitus
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    Exp Clin Endocrinol Diabetes 112:429-34. 2004
    ..To determine the counterregulatory hormonal responses to severe hypoglycaemia (SH) in type 1 versus insulin-treated type 2 diabetic patients under everyday conditions...
  15. ncbi request reprint Lipodystrophy and metabolic disorders as complication of antiretroviral therapy of HIV infection
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Germany
    Exp Clin Endocrinol Diabetes 109:389-92. 2001
    ....
  16. ncbi request reprint Lower incidence of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamide
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    Diabetes Metab Res Rev 17:467-73. 2001
    ..Severe hypoglycaemia is a potentially life-threatening condition. The aim of the present study was to compare the frequency of severe hypoglycaemia in patients with type 2 diabetes treated with glimepiride versus glibenclamide...
  17. ncbi request reprint Structural and process quality in the management of diabetic emergencies in Germany
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    Int J Qual Health Care 14:33-8. 2002
    ..The purpose of this investigation was, therefore, to collect representative data on these indicators for the whole of Germany...
  18. ncbi request reprint Clinical implications of hepatogenous diabetes in liver cirrhosis
    Andreas Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Röntgenstrasse 18, D 32756 Detmold, Germany
    J Gastroenterol Hepatol 17:677-81. 2002
    ..The aim of the present study was to examine the clinical and therapeutic implications and the prognostic significance of hepatogenous diabetes in patients with liver cirrhosis...
  19. ncbi request reprint Characteristics and time course of severe glimepiride- versus glibenclamide-induced hypoglycaemia
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Röntgenstrasse 18, 32756 Detmold, Germany
    Eur J Clin Pharmacol 59:91-7. 2003
    ..To compare the clinical characteristics and time course of severe hypoglycaemia (SH) on glimepiride and the reference drug glibenclamide...
  20. ncbi request reprint Prehospital management of diabetic emergencies--a population-based intervention study
    A Holstein
    1st Department of Medicine and Institute of Anaesthesiology, Klinikum Lippe Detmold, Detmold, Germany
    Acta Anaesthesiol Scand 47:610-5. 2003
    ..A study was performed to obtain reliable data about the prevalence of diabetic emergencies and to improve the quality of prehospital care of patients with diabetes-related emergencies...
  21. ncbi request reprint Clinical characterisation of severe hypoglycaemia--a prospective population-based study
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    Exp Clin Endocrinol Diabetes 111:364-9. 2003
    ..To determine the clinical characteristics of severe hypoglycaemia (SH) in a nonselected German population. SH was defined as an event requiring intravenous glucose or glucagon injection...
  22. ncbi request reprint Risk of hypoglycaemia with oral antidiabetic agents in patients with Type 2 diabetes
    A Holstein
    1st Department of Medicine, Klinikum Lippe Detmold, Detmold, Germany
    Exp Clin Endocrinol Diabetes 111:405-14. 2003
    ..Repaglinide might be beneficial in individuals with renal impairment...
  23. ncbi request reprint Hormonal counterregulation and consecutive glimepiride serum concentrations during severe hypoglycaemia associated with glimepiride therapy
    A Holstein
    1st Department of Medicine, Klinikum Lippe, Röntgenstrasse 18, 32756, Detmold, Germany
    Eur J Clin Pharmacol 59:747-54. 2003
    ..To examine the release of counterregulatory hormones and consecutive glimepiride serum concentrations during severe hypoglycaemia (SH) associated with glimepiride therapy...
  24. doi request reprint Lipoatrophy associated with the use of insulin analogues: a new case associated with the use of insulin glargine and review of the literature
    Andreas Holstein
    1st Department of Medicine, Lippe Detmold Clinic, Röntgenstr 18, Detmold, D 32756, Germany
    Expert Opin Drug Saf 9:225-31. 2010
    ..No spontaneous substantial recovery of lipoatrophic areas has been reported. Frequent use of the same pen needle and lack of rotating of insulin injection sites seem to favour the development of lipoatrophy...
  25. ncbi request reprint The Glu23Lys polymorphism in KCNJ11 and impaired hypoglycaemia awareness in patients with type 1 diabetes
    Andreas Holstein
    1st Department of Medicine, Clinic Lippe Detmold, Detmold, Germany
    J Hum Genet 50:530-3. 2005
    ..Even though the study provides a relatively large dataset, it is possible that small differences may have been missed...
  26. doi request reprint The E23K variant of KCNJ11 and the risk for severe sulfonylurea-induced hypoglycemia in patients with type 2 diabetes
    A Holstein
    First Department of Medicine, Clinic Lippe Detmold, Detmold, Germany
    Horm Metab Res 41:387-90. 2009
    ..Our data suggest that patients with T2D carrying the K variant of the E23K polymorphism in KCNJ11 have reduced response to sulfonylurea therapy, which results in increased HbA(1c) and consequently in lower risk for SH...
  27. ncbi request reprint Contraindications can damage your health--is metformin a case in point?
    A Holstein
    Clinic Lippe, First Department of Medicine, Detmold, Germany
    Diabetologia 48:2454-9. 2005
    ..A clear re-definition of contraindications to metformin will enable more physicians to prescribe within guidelines...
  28. pmc Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents
    A Holstein
    1st Department of Medicine, Klinikum Lippe, Detmold, Germany
    Br J Clin Pharmacol 60:103-6. 2005
    ..The aim of this study was to test the hypothesis that individuals with genotypes predicting low CYP2C9 activity may be at a higher risk of severe drug-associated hypoglycaemia...
  29. ncbi request reprint Practicality and accuracy of prehospital rapid venous blood glucose determination
    A Holstein
    1st Department of Medicine and the Institute of Anesthesiology, Klinikum Lippe Detmold, Germany
    Am J Emerg Med 18:690-4. 2000
    ..The method of collecting whole blood directly from the venous access is simple and robust, and is independent of the hemodynamic status of the patient...
  30. ncbi request reprint The Ser1369Ala variant of ABCC8 and the risk for severe sulfonylurea-induced hypoglycemia in German patients with Type 2 diabetes
    Judith Dina Holstein
    Medical Department, University of Leipzig, Leipzig, Germany
    Pharmacogenomics 13:5-7. 2012
    ..A letter in response to: Sato R, Watanabe H, Genma R et al. ABCC8 polymorphism (Ser1369Ala): influence on severe hypoglycemia due to sulfonylureas. Pharmacogenomics 11(12), 1743-1750 (2010)...
  31. ncbi request reprint The insertion/deletion polymorphism in the angiotensin-converting enzyme gene and hypoglycemia awareness in patients with type 1 diabetes
    A Holstein
    1st Department of Medicine, Clinic Lippe Detmold, Detmold, Germany
    Horm Metab Res 38:603-6. 2006
    ..Even though the study provides a relatively large dataset, it is possible that small differences may have been missed...
  32. ncbi request reprint Blood glucose self-monitoring from abdominal skin: a precise and virtually pain-free method
    A Holstein
    First Department of Medicine, Klinikum Lippe Detmold, Germany
    Acta Diabetol 39:97-104. 2002
    ..SM from abdomal skin is a simple, virtually pain-free and precise method. It provides certain diabetic patients with an alternative to the established method of SM from the fingertip...
  33. ncbi request reprint Incidence and costs of severe hypoglycemia
    Andreas Holstein
    Diabetes Care 25:2109-10. 2002