Kay Hofmann

Summary

Country: Germany

Publications

  1. ncbi Ubiquitin-binding domains and their role in the DNA damage response
    Kay Hofmann
    Bioinformatics Group, Miltenyi Biotec GmbH, Friedrich Ebert Strasse 68, 51429 Bergisch Gladbach, Germany
    DNA Repair (Amst) 8:544-56. 2009
  2. ncbi Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, Koln, Germany
    Hum Mol Genet 12:2845-52. 2003
  3. ncbi Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, Stöckheimer Weg 1, D 50829 Köln, Germany
    BMC Bioinformatics 6:71. 2005
  4. ncbi A common protein interaction domain links two recently identified epilepsy genes
    Hartmut Scheel
    Bioinformatics Group, MEMOREC Stoffel GmbH, Stöckheimer Weg 1, D 50829 Köln, Germany
    Hum Mol Genet 11:1757-62. 2002
  5. ncbi Sequence similarity in structurally dissimilar proteins
    Stefan Tomiuk
    Bioinformatics Group, MEMOREC Stoffel GmbH, , , Germany
    Curr Biol 13:R124-5. 2003
  6. ncbi A novel interaction motif, SARAH, connects three classes of tumor suppressor
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, , , Germany
    Curr Biol 13:R899-900. 2003

Collaborators

Detail Information

Publications6

  1. ncbi Ubiquitin-binding domains and their role in the DNA damage response
    Kay Hofmann
    Bioinformatics Group, Miltenyi Biotec GmbH, Friedrich Ebert Strasse 68, 51429 Bergisch Gladbach, Germany
    DNA Repair (Amst) 8:544-56. 2009
    ..For several repair pathways, current knowledge of the events downstream of the ubiquitin mark is sketchy. A closer look at orphan UBD proteins might lead to the identification of missing pieces in the DNA response puzzle...
  2. ncbi Elucidation of ataxin-3 and ataxin-7 function by integrative bioinformatics
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, Koln, Germany
    Hum Mol Genet 12:2845-52. 2003
    ..Moreover, both findings have implications for the general pathogenesis of spinocerebellar ataxias by providing a direct connection of these diseases with ubiquitin metabolism and histone acetylation...
  3. ncbi Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexes
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, Stöckheimer Weg 1, D 50829 Köln, Germany
    BMC Bioinformatics 6:71. 2005
    ..Initially, the PCI domain was defined as the region of detectable sequence similarity between the components mentioned above...
  4. ncbi A common protein interaction domain links two recently identified epilepsy genes
    Hartmut Scheel
    Bioinformatics Group, MEMOREC Stoffel GmbH, Stöckheimer Weg 1, D 50829 Köln, Germany
    Hum Mol Genet 11:1757-62. 2002
    ..The EAR domain is likely to play an important role in the pathogenesis of epilepsy, either by binding to an unknown anti-epileptic ligand, or more likely by interfering with axon guidance or synaptogenesis...
  5. ncbi Sequence similarity in structurally dissimilar proteins
    Stefan Tomiuk
    Bioinformatics Group, MEMOREC Stoffel GmbH, , , Germany
    Curr Biol 13:R124-5. 2003
  6. ncbi A novel interaction motif, SARAH, connects three classes of tumor suppressor
    Hartmut Scheel
    Bioinformatics Group, Memorec Biotec GmbH, , , Germany
    Curr Biol 13:R899-900. 2003