- Residues at the tip of the pore loop of NR3B-containing NMDA receptors determine Ca2+ permeability and Mg2+ blockNora A Cavara
Department of Biochemistry I Receptor Biochemistry, Ruhr University Bochum, Universitaetsstrasse 150, D 44780 Bochum, Germany
BMC Neurosci 11:133. 2010..The recently discovered NR3 subunits feature an unprecedented glycine-arginine combination at those critical sites within the pore. Diheteromers assembled from NR1 and NR3 are not blocked by Mg2+ and are not permeable for Ca2+...