J Hess

Summary

Country: Germany

Publications

  1. pmc Mycobacterium bovis Bacille Calmette-Guérin strains secreting listeriolysin of Listeria monocytogenes
    J Hess
    Max Planck Institute for Infection Biology, Monbijoustrasse 2, D 10117 Berlin, Germany
    Proc Natl Acad Sci U S A 95:5299-304. 1998
  2. ncbi request reprint Protection against murine tuberculosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the 30-kDa antigen of Mycobacterium bovis BCG
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, Monbijoustr 2, D 10117, Berlin, Germany
    FEMS Immunol Med Microbiol 27:283-9. 2000
  3. ncbi request reprint Secretion of different listeriolysin cognates by recombinant attenuated Salmonella typhimurium: superior efficacy of haemolytic over non-haemolytic constructs after oral vaccination
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, D 10117, Berlin, Germany
    Microbes Infect 2:1799-806. 2000
  4. ncbi request reprint Impact of intracellular location of and antigen display by intracellular bacteria: implications for vaccine development
    S H Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany
    Immunol Lett 65:81-4. 1999
  5. ncbi request reprint The need for a novel generation of vaccines
    S H Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany
    Immunobiology 201:272-82. 1999
  6. ncbi request reprint Live antigen carriers as tools for improved anti-tuberculosis vaccines
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    FEMS Immunol Med Microbiol 23:165-73. 1999
  7. ncbi request reprint Development of novel tuberculosis vaccines
    J Hess
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    C R Acad Sci III 322:953-8. 1999
  8. ncbi request reprint Contribution of MHC class I-dependent immune mechanisms induced by attenuated recombinant Salmonella typhimurium secreting superoxide dismutase to protection against murine listeriosis
    L Grode
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, 10117, Berlin, Germany
    Vaccine 19:3269-72. 2001
  9. ncbi request reprint Immune response against Mycobacterium tuberculosis: implications for vaccine development
    S H Kaufmann
    Department of Immunology, Max Planck Institute for Infection Biology, Monbijoustr 2, D 10117, Berlin, Germany
    J Biotechnol 83:13-7. 2000
  10. ncbi request reprint Protective efficacy against tuberculosis of ESAT-6 secreted by a live Salmonella typhimurium vaccine carrier strain and expressed by naked DNA
    H J Mollenkopf
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr 21 22, 10117 Berlin, Germany
    Vaccine 19:4028-35. 2001

Collaborators

Detail Information

Publications10

  1. pmc Mycobacterium bovis Bacille Calmette-Guérin strains secreting listeriolysin of Listeria monocytogenes
    J Hess
    Max Planck Institute for Infection Biology, Monbijoustrasse 2, D 10117 Berlin, Germany
    Proc Natl Acad Sci U S A 95:5299-304. 1998
    ..Because CD8 T cells play a major role in protection against tuberculosis such Hly secreting r-BCG constructs are antituberculosis vaccine candidates...
  2. ncbi request reprint Protection against murine tuberculosis by an attenuated recombinant Salmonella typhimurium vaccine strain that secretes the 30-kDa antigen of Mycobacterium bovis BCG
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, Monbijoustr 2, D 10117, Berlin, Germany
    FEMS Immunol Med Microbiol 27:283-9. 2000
    ..These data suggest that the HlyB/HlyD/TolC-based antigen delivery system with attenuated r-S. typhimurium as carrier is capable of inducing an immune response against mycobacterial antigens...
  3. ncbi request reprint Secretion of different listeriolysin cognates by recombinant attenuated Salmonella typhimurium: superior efficacy of haemolytic over non-haemolytic constructs after oral vaccination
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, D 10117, Berlin, Germany
    Microbes Infect 2:1799-806. 2000
    ..Therefore, rSalmonella strains secreting biologically active Hly represent valuable delivery systems for heterologous rAg or DNA which should be exploited for future mucosal vaccination strategies...
  4. ncbi request reprint Impact of intracellular location of and antigen display by intracellular bacteria: implications for vaccine development
    S H Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany
    Immunol Lett 65:81-4. 1999
    ..Secreted antigen display was found to be superior to somatic antigen display. Hence, we consider antigen secretion a major prerequisite of an effective vaccine against intracellular bacteria...
  5. ncbi request reprint The need for a novel generation of vaccines
    S H Kaufmann
    Max Planck Institute for Infection Biology, Berlin, Germany
    Immunobiology 201:272-82. 1999
    ..These encompass recombinant vaccine carriers expressing, and naked DNA constructs encoding, heterologous antigens. Both vaccination strategies proved to be protective in the model of experimental listeriosis of mice...
  6. ncbi request reprint Live antigen carriers as tools for improved anti-tuberculosis vaccines
    J Hess
    Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany
    FEMS Immunol Med Microbiol 23:165-73. 1999
    ..In addition, we report on our r-Salmonella typhimurium expression system combined with the HlyB/HlyD/ TolC export machinery for delivering the prominent mycobacterial antigen Ag85B for immune recognition...
  7. ncbi request reprint Development of novel tuberculosis vaccines
    J Hess
    Department of Immunology, Max Planck Institute for Infection Biology, Berlin, Germany
    C R Acad Sci III 322:953-8. 1999
    ..A rational judgement on the efficacy of the different types of vaccine currently under development needs to await further evaluation...
  8. ncbi request reprint Contribution of MHC class I-dependent immune mechanisms induced by attenuated recombinant Salmonella typhimurium secreting superoxide dismutase to protection against murine listeriosis
    L Grode
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstrasse 21 22, 10117, Berlin, Germany
    Vaccine 19:3269-72. 2001
    ..monocytogenes. Our data suggest a role of TAP-dependent mechanisms in priming of protective immunity by rSalmonella micro-organisms secreting SOD...
  9. ncbi request reprint Immune response against Mycobacterium tuberculosis: implications for vaccine development
    S H Kaufmann
    Department of Immunology, Max Planck Institute for Infection Biology, Monbijoustr 2, D 10117, Berlin, Germany
    J Biotechnol 83:13-7. 2000
    ..Second, the whole bacterial vaccine approach relying on multiple antigens and built-in adjuvanticity. Time will tell which type of vaccine is best suited for eradication of tuberculosis...
  10. ncbi request reprint Protective efficacy against tuberculosis of ESAT-6 secreted by a live Salmonella typhimurium vaccine carrier strain and expressed by naked DNA
    H J Mollenkopf
    Max Planck Institute for Infection Biology, Department of Immunology, Schumannstr 21 22, 10117 Berlin, Germany
    Vaccine 19:4028-35. 2001
    ..Vaccination with a single dose of r S. typhimurium secreting ESAT-6 reduced numbers of tubercle bacilli in the lungs throughout the course of infection. The combined prime-boost vaccination did not considerably enhance protection...