Hans Herzog

Summary

Country: Germany

Publications

  1. ncbi [Chemistry and physics of scanners. PET- and SPECT-techniques]
    Hans Herzog
    , ,
    Pharm Unserer Zeit 34:468-73. 2005
  2. ncbi PET/MRI: challenges, solutions and perspectives
    Hans Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Z Med Phys 22:281-98. 2012
  3. ncbi Combined PET/MR systems: an overview and comparison of currently available options
    H Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, Julich, Germany
    Q J Nucl Med Mol Imaging 56:247-67. 2012
  4. ncbi Biodistribution and radiation dosimetry of the A1 adenosine receptor ligand 18F-CPFPX determined from human whole-body PET
    Hans Herzog
    Institute of Neuroscience and Biophysics Medicine, Forschungszentrum Juelich GmbH, D 52425, Juelich, Germany
    Eur J Nucl Med Mol Imaging 35:1499-506. 2008
  5. ncbi Motion artifact reduction on parametric PET images of neuroreceptor binding
    Hans Herzog
    Institute of Medicine, Forschungszentrum Juelich, D 52425 Juelich, Germany
    J Nucl Med 46:1059-65. 2005
  6. ncbi Assessment of the short-lived non-pure positron-emitting nuclide (120)I for PET imaging
    H Herzog
    Institute of Medicine, Forschungszentrum Juelich, 52425 Juelich, Germany
    Eur J Nucl Med Mol Imaging 33:1249-57. 2006
  7. ncbi High resolution BrainPET combined with simultaneous MRI
    H Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Nuklearmedizin 50:74-82. 2011
  8. ncbi PET quantitation and imaging of the non-pure positron-emitting iodine isotope 124I
    H Herzog
    Institute of Medicine, Forschungszentrum Jülich GmhH, Germany
    Appl Radiat Isot 56:673-9. 2002
  9. ncbi The current state, challenges and perspectives of MR-PET
    Hans Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Neuroimage 49:2072-82. 2010
  10. ncbi Multiple indicators of age-related differences in cerebral white matter and the modifying effects of hypertension
    S Burgmans
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neuroimage 49:2083-93. 2010

Detail Information

Publications52

  1. ncbi [Chemistry and physics of scanners. PET- and SPECT-techniques]
    Hans Herzog
    , ,
    Pharm Unserer Zeit 34:468-73. 2005
  2. ncbi PET/MRI: challenges, solutions and perspectives
    Hans Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Z Med Phys 22:281-98. 2012
    ..While describing the present instrumentation for human PET/MRI, this review discusses the challenges and promises related to this new imaging technology...
  3. ncbi Combined PET/MR systems: an overview and comparison of currently available options
    H Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, Julich, Germany
    Q J Nucl Med Mol Imaging 56:247-67. 2012
    ..Based on own experiences and those reported in different publications a number of open issues are discussed. Finally a short comparative analysis on the status and perspectives of human PET/MR imaging is given...
  4. ncbi Biodistribution and radiation dosimetry of the A1 adenosine receptor ligand 18F-CPFPX determined from human whole-body PET
    Hans Herzog
    Institute of Neuroscience and Biophysics Medicine, Forschungszentrum Juelich GmbH, D 52425, Juelich, Germany
    Eur J Nucl Med Mol Imaging 35:1499-506. 2008
    ..The purpose of this study was to determine the biodistribution and the radiation dose of (18)F-CPFPX by whole-body scans in humans...
  5. ncbi Motion artifact reduction on parametric PET images of neuroreceptor binding
    Hans Herzog
    Institute of Medicine, Forschungszentrum Juelich, D 52425 Juelich, Germany
    J Nucl Med 46:1059-65. 2005
    ..We report the effect of motion on parametric images of the distribution volume ratio (DVR), as well as possible improvements if the dynamic PET data are corrected for head movements...
  6. ncbi Assessment of the short-lived non-pure positron-emitting nuclide (120)I for PET imaging
    H Herzog
    Institute of Medicine, Forschungszentrum Juelich, 52425 Juelich, Germany
    Eur J Nucl Med Mol Imaging 33:1249-57. 2006
    ..120)I has a positron abundance more than twice that of (124)I and a maximum positron energy of 4 MeV. This study was undertaken to evaluate and characterise the qualitative and quantitative PET imaging of (120)I...
  7. ncbi High resolution BrainPET combined with simultaneous MRI
    H Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Nuklearmedizin 50:74-82. 2011
    ..DISCUSSION, CONCLUSION: Initial experiences with the hybrid MRI/BrainPET indicate a promising basis for further developments of this unique technique allowing simultaneous PET imaging combined with both anatomical and functional MRI...
  8. ncbi PET quantitation and imaging of the non-pure positron-emitting iodine isotope 124I
    H Herzog
    Institute of Medicine, Forschungszentrum Jülich GmhH, Germany
    Appl Radiat Isot 56:673-9. 2002
    ..We conclude that quantitation of a radiopharmaceutical labelled with 124I is feasible and may be improved by the development of specific corrections...
  9. ncbi The current state, challenges and perspectives of MR-PET
    Hans Herzog
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich, 52425 Julich, Germany
    Neuroimage 49:2072-82. 2010
    ..This report presents a critical summary of the contributions made to the workshop...
  10. ncbi Multiple indicators of age-related differences in cerebral white matter and the modifying effects of hypertension
    S Burgmans
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neuroimage 49:2083-93. 2010
    ..These findings indicate that of all examined measures, diffusion-based indices of white matter integrity may be the most sensitive indicators of global and regional declines and vascular damage in the aging brain...
  11. ncbi PET imaging problems with the non-standard positron emitters Yttrium-86 and Iodine-124
    H Herzog
    Institute of Medicine, Jülich GmbH Research Center, Julich, Germany
    Q J Nucl Med Mol Imaging 52:159-65. 2008
    ....
  12. ncbi Preferred stereoselective transport of the D-isomer of cis-4-[18F]fluoro-proline at the blood-brain barrier
    Karl Josef Langen
    Institute of Medicine, Research Centre Julich, Julich, Germany
    J Cereb Blood Flow Metab 25:607-16. 2005
    ..Thus, D-Pro in the plasma might be a source of intracerebral L-proline, which has been shown to act as a modulator of excitatory neurotransmission...
  13. ncbi Concepts of registration and correction of head motion in positron emission tomography
    Lutz Tellmann
    Institute of Medicine, Forschungszentrum Juelich, D 52425 Juelich, Germany
    Z Med Phys 16:67-74. 2006
    ..The effects of motion correction are demonstrated on the basis of phantom measurements and patient data. The influence of motion correction on parametric imaging is described in a receptor study...
  14. ncbi Cerebral A1 adenosine receptors (A1AR) in liver cirrhosis
    Christian Boy
    Brain Imaging Centre West, Institute of Medicine, Research Centre Julich, Julich, Germany
    Eur J Nucl Med Mol Imaging 35:589-97. 2008
    ..The present study investigates changes of cerebral A(1)AR binding in cirrhotic patients by means of positron emission tomography (PET) and [(18)F]CPFPX, a novel selective A(1)AR antagonist...
  15. ncbi Role of O-(2-(18)F-fluoroethyl)-L-tyrosine PET for differentiation of local recurrent brain metastasis from radiation necrosis
    Norbert Galldiks
    Institute of Neuroscience and Medicine INM 3, 4, 5, Forschungszentrum Julich, Julich, Germany
    J Nucl Med 53:1367-74. 2012
    ....
  16. ncbi In vivo imaging of adenosine A1 receptors in the human brain with [18F]CPFPX and positron emission tomography
    Andreas Bauer
    Institute of Medicine, Research Center Julich, D 52425 Julich, Germany
    Neuroimage 19:1760-9. 2003
    ..In conclusion, in vivo application of [(18)F]CPFPX, a highly potent and selective PET ligand, for the first time allows the imaging of A(1)ARs in the living human brain...
  17. ncbi Multimodal imaging utilising integrated MR-PET for human brain tumour assessment
    Irene Neuner
    Institute of Neuroscience and Medicine 4, INM 4, Forschungszentrum Julich, 52428, Julich, Germany
    Eur Radiol 22:2568-80. 2012
    ..The differentiation of post-therapeutic scar tissue, tumour rests and tumour recurrence is challenging. The relationship to structures such as the pyramidal tract to the tumour mass influences the therapeutic neurosurgical approach...
  18. ncbi Comparison of (18)F-FET and (18)F-FDG PET in brain tumors
    Dirk Pauleit
    Institute of Neuroscience and Medicine, Forschungszentrum Julich, D 52425 Julich, Germany
    Nucl Med Biol 36:779-87. 2009
    ....
  19. ncbi Cognition-induced modulation of serotonin in the orbitofrontal cortex: a controlled cross-over PET study of a delayed match-to-sample task using the 5-HT2a receptor antagonist [18F]altanserin
    Hubertus Hautzel
    Department of Nuclear Medicine KME, Forschungszentrum Julich, Julich, Germany
    Neuroimage 58:905-11. 2011
    ....
  20. ncbi Analytical calculation of volumes-of-intersection for iterative, fully 3-D PET reconstruction
    Jürgen J Scheins
    Institute of Medicine, Research Center Julich, Julich 52425, Germany
    IEEE Trans Med Imaging 25:1363-9. 2006
    ..A comparison of the performance of the reconstruction using LOI weighting and VOI weighting is presented...
  21. ncbi Imaging of gliomas with Cis-4-[18F]fluoro-L-proline
    Karl J Langen
    Institute of Medicine, Research Centre Julich, Julich, Germany
    Nucl Med Biol 31:67-75. 2004
    ..Control of MRI suggested tumor growth in these areas at further follow up. Our results indicate that in most gliomas increased cis-FPro uptake is restricted to areas with disruption of the BBB which limits its clinical utility...
  22. ncbi Modulation of a brain-behavior relationship in verbal working memory by rTMS
    Felix M Mottaghy
    Department of Nuclear Medicine KME, Heinrich Heine University and Research Center Jülich, D 52426 Jülich, Germany
    Brain Res Cogn Brain Res 15:241-9. 2003
    ..The results are discussed along the idea of a short-term plasticity in an active neuronal network that reacts to an rTMS-induced temporary disruption of two different network modules...
  23. ncbi Fully-3D PET image reconstruction using scanner-independent, adaptive projection data and highly rotation-symmetric voxel assemblies
    J J Scheins
    Institute of Neuroscience and Medicine, Forschungszentrum Julich GmbH, D 52425 Julich, Germany
    IEEE Trans Med Imaging 30:879-92. 2011
    ..The higher computational effort due to the more accurate image space sampling provides significantly improved images in terms of resolution and noise...
  24. ncbi Cerebral haemodynamics during hypo- and hypercapnia: determination with simultaneous 15O-butanol-PET and transcranial Doppler sonography
    T D Poeppel
    Klinik für Nuklearmedizin KME der Heinrich Heine Universität, Forschungszentrum Julich, 52426 Juelich, Germany e mail
    Nuklearmedizin 46:93-100. 2007
    ..The aim of our study was the comparison of vasomotor reactivity assessed with simultaneous TCD and quantitative regional CBF-measurements (rCBF) by PET (serving as the reference method for in-vivo quantification of rCBF)...
  25. ncbi Network analysis in episodic encoding and retrieval of word-pair associates: a PET study
    B J Krause
    Department of Nuclear Medicine, Heinrich Heine University Hospital, Dusseldorf, Germany
    Eur J Neurosci 11:3293-301. 1999
    ..Our results further underline the role of the precuneus in episodic memory, not only during retrieval but also during encoding...
  26. ncbi The motion aftereffect: more than area V5/MT? Evidence from 15O-butanol PET studies
    H Hautzel
    Department of Nuclear Medicine, Heinrich Heine University, Dusseldorf, Germany
    Brain Res 892:281-92. 2001
    ....
  27. ncbi [The (11C) acetate positron emission tomography in prostatic carcinoma. New prospects in metabolic imaging]
    H Hautzel
    Nuklearmedizinische Klinik, Heinrich Heine Universitat Dusseldorf
    Urologe A 41:569-76. 2002
    ....
  28. ncbi Uptake of cis-4-[18F]fluoro-L-proline in urologic tumors
    K J Langen
    Institutes of Medicine and Nuclear Chemistry, , , Germany
    J Nucl Med 42:752-4. 2001
    ..FDG uptake was seen in one of the three primary RCCs, in the local recurrence of RCC, in the squamous RCC, and in the metastases of penile cancer. CONCLUSION: Cis-FPro appears not to be a promising PET tracer in oncology...
  29. ncbi Brain systems engaged in encoding and retrieval of word-pair associates independent of their imagery content or presentation modalities
    D Schmidt
    Department of Nuclear Medicine, Heinrich Heine University Hospital, Dusseldorf, Germany
    Neuropsychologia 40:457-70. 2002
    ..Finally, our results provide strong evidence that mesial parietal cortex (precuneus) involvement is not restricted to processes involving imagery...
  30. ncbi MR-based PET motion correction procedure for simultaneous MR-PET neuroimaging of human brain
    Marcus Görge Ullisch
    Forschungszentrum Julich, Institute of Neuroscience and Medicine 4, Medical Imaging Physics, Forschungszentrum Julich GmbH, Julich, Germany
    PLoS ONE 7:e48149. 2012
    ..In vivo motion corrected images show an evident increase of contrast at the basal ganglia and a good visibility of uptake in tiny structures such as superior colliculi...
  31. ncbi Analysis and correction of count rate reduction during simultaneous MR-PET measurements with the BrainPET scanner
    Christoph Weirich
    Institute of Neuroscience and Medicine, Forschungszentrum Julich GmbH, Julich, Germany
    IEEE Trans Med Imaging 31:1372-80. 2012
    ..For clinical sequences routinely used in hybrid MR-BrainPET measurements, a correction method has been designed, implemented, and evaluated ...
  32. ncbi Interdependence of regional and global cerebral blood flow during visual stimulation: an O-15-butanol positron emission tomography study
    L J Kemna
    , , Germany
    J Cereb Blood Flow Metab 21:664-70. 2001
    ..At low PETCO2, the activation-induced flow changes are moderately damped, whereas at high PETCO2, they are nearly lost (deltaCBF (+/-SD): 52% +/- 25%, 68% +/- 22%, 16% +/- 25% at PETCO2 = 20, 40, 70 mm Hg, respectively)...
  33. ncbi Does PET/MR in human brain imaging provide optimal co-registration? A critical reflection
    Uwe Pietrzyk
    Institute of Neurosciences and Medicine, Forschungszentrum Julich GmbH, 52425 Julich, Germany
    MAGMA 26:137-47. 2013
    ..This paper will briefly summarize the current status of PET/MR within the framework of developments for image co-registration and discuss current limitations and future perspectives...
  34. ncbi Hybrid 18F-FDG PET-MRI of the hand in rheumatoid arthritis: initial results
    Falk Miese
    Institute of Neuroscience and Medicine 4, Forschungszentrum Julich GmbH, Julich, Germany
    Clin Rheumatol 30:1247-50. 2011
    ..Maximum SUV of 3.1 was noted. In RA, true hybrid 18F-FDG PET-MRI of the hand is technically feasible and bears the potential to directly visualize inflammation...
  35. ncbi Neural responses to the production and comprehension of syntax in identical utterances
    Peter Indefrey
    Institute of Medicine, Research Center Julich, Germany
    Brain Lang 89:312-9. 2004
    ....
  36. ncbi Acute S-ketamine application does not alter cerebral [18F]altanserin binding: a pilot PET study in humans
    A Matusch
    Institute of Medicine and Brain Imaging Center West, Research Center Juelich, Juelich, Germany
    J Neural Transm 114:1433-42. 2007
    ..Advantageously, the stability of [(18)F]altanserin PET towards acute influences is a prerequisite for its future use to detect sub-acute and chronic effects of ketamine...
  37. ncbi Implication of 2-18fluor-2-deoxyglucose positron emission tomography in the follow-up of Hürthle cell thyroid cancer
    Michail Plotkin
    Department of Nuclear Medicine, Heinrich Heine University Hospital Dusseldorf, Germany
    Thyroid 12:155-61. 2002
    ..This study supports the efficiency of FDG-PET in the follow-up of HTC...
  38. ncbi Activation differences in observation of hand movements for imitation or velocity judgement
    Boris Suchan
    Institute of Cognitive Neuroscience, Department of Neuropsychology, Ruhr University Bochum, Germany
    Behav Brain Res 188:78-83. 2008
    ..Thus, movement observation recruits non-overlapping cortical networks, depending on the information attended to which are characterised by a dorsal ventral dissociation...
  39. ncbi Hemispheric dissociation of visual-pattern processing and visual rotation
    Boris Suchan
    Department of Clinical Neuropsychology, Ruhr University of Bochum, Universitatsstr 150, 44780 Bochum, Germany
    Behav Brain Res 136:533-44. 2002
    ..The present results suggest a hemispheric dissociation of fronto-parietal circuits with a left dominance for visual pattern processing like storage and a right dominance for visuospatial processing...
  40. ncbi Whole-body distribution and dosimetry of O-(2-[18F]fluoroethyl)-L-tyrosine
    Dirk Pauleit
    Clinic of Nuclear Medicine, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Eur J Nucl Med Mol Imaging 30:519-24. 2003
    ..5.3% ID/h). The highest absorbed dose was found for the urinary bladder wall. The effective dose according to ICRP 60 was 16.5 micro Sv/MBq for adults, which would lead to an effective dose of 6.1 mSv in a PET study using 370 MBq FET...
  41. ncbi Network for auditory intrinsic alertness: a PET study
    Walter Sturm
    Neurological Clinic, Neuropsychology, RWTH Aachen, University Hospital, Technical University Aachen, Pauwelsstrasse 30, D 52074, Aachen, Germany
    Neuropsychologia 42:563-8. 2004
    ....
  42. ncbi PET identifies transitional metabolic change in the spinal cord following a subthreshold dose of irradiation
    Olga Esik
    Department of Oncotherapy, Pécs University of Sciences, Pecs, Hungary
    Pathol Oncol Res 10:42-6. 2004
    ....
  43. ncbi Decreased prefrontal 5-HT2A receptor binding in subjects at enhanced risk for schizophrenia
    Rene Hurlemann
    Department of Psychiatry, University of Bonn, Sigmund Freud Str 25, 53105 Bonn, Germany
    Anat Embryol (Berl) 210:519-23. 2005
    ....
  44. ncbi PET with O-(2-18F-Fluoroethyl)-L-Tyrosine in peripheral tumors: first clinical results
    Dirk Pauleit
    Clinic of Nuclear Medicine, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    J Nucl Med 46:411-6. 2005
    ..O-(2-18F-Fluoroethyl)-L-Tyrosine (18F-FET) PET has shown promising results in brain tumor diagnosis. The aim of this prospective study was to evaluate 18F-FET PET in comparison with 18F-FDG PET in patients with peripheral tumors...
  45. ncbi Subthalamic stimulation modulates cortical control of urinary bladder in Parkinson's disease
    Jan Herzog
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Brain 129:3366-75. 2006
    ..The data suggest that STN-DBS ameliorates bladder dysfunction and that this modulation may result from facilitated processing of afferent bladder information...
  46. ncbi Direct Fourier method in 3D PET using accurately determined frequency sample distribution
    Yingbo Li
    Fac. of Electr, Inf. and Media Eng, Wuppertal Univ
    Conf Proc IEEE Eng Med Biol Soc 1:3787-90. 2006
    ..Direct Fourier method (DFM) is applied for the reconstruction due to its speed advantage. Simulation studies are accomplished to verify the imposed assertion...
  47. ncbi Improved sensory gating of urinary bladder afferents in Parkinson's disease following subthalamic stimulation
    Jan Herzog
    Department of Neurology, Christian Albrechts University Kiel, Schittenhelmstrasse 10, 24105 Kiel, Germany
    Brain 131:132-45. 2008
    ..Furthermore, this is the first imaging study, which shows an effect of STN-DBS on sensory gating in PD patients and its neural basis...
  48. ncbi Neural correlates of visuospatial imagery
    Boris Suchan
    Department of Clinical Neuropsychology, Ruhr University of Bochum, Universitatsstr 150, 44780, Bochum, Germany
    Behav Brain Res 131:163-8. 2002
    ..Since these activation areas are close to those in imagery of movement trajectories, we concluded that they appear to be a subsystem for processing mental visuospatial images...
  49. ncbi Common and differential neural mechanisms supporting imitation of meaningful and meaningless actions
    Raffaella I Rumiati
    Cognitive Neuroscience Sector, Scuola Internazionale Superiore di Studi Avanzati SISSA, Trieste, Italy
    J Cogn Neurosci 17:1420-31. 2005
    ..In contrast, imitation of meaningful actions differentially involves semantic processing as evidenced by activation of areas belonging to the ventral stream...
  50. ncbi Functional reorganisation in patients with right hemisphere stroke after training of alertness: a longitudinal PET and fMRI study in eight cases
    Walter Sturm
    Neurological Clinic, University Hospital RWTH Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
    Neuropsychologia 42:434-50. 2004
    ....
  51. ncbi Lexical decision of nonwords and pseudowords in humans: a positron emission tomography study
    Karsten Specht
    Division of Neurolinguistics, Neurology Department, University Hospital Aachen, Aachen, Germany
    Neurosci Lett 345:177-81. 2003
    ..The data support the notion that the lexical decision during a nonword task is mainly based on a phonological discrimination process, whereas a pseudoword task more strongly requires lexical access resulting in activation of BA 47...
  52. ncbi Smoking upregulates alpha4beta2* nicotinic acetylcholine receptors in the human brain
    Ullrich Wullner
    Department of Neurology, University Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Neurosci Lett 430:34-7. 2008
    ..The up-regulation of alpha4beta2* nAChR upon chronic nicotine exposure via tobacco smoking incorporates subcortical brain regions which may play an important role in nicotine addiction...