A Herpin

Summary

Country: Germany

Publications

  1. pmc Specification of primordial germ cells in medaka (Oryzias latipes)
    Amaury Herpin
    Department of Physiological Chemistry I, University of Wuerzburg, Biozentrum, Am Hubland, D 97074 Wuerzburg, Germany
    BMC Dev Biol 7:3. 2007
  2. pmc Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bY
    Amaury Herpin
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    BMC Dev Biol 7:99. 2007
  3. pmc Divergent expression regulation of gonad development genes in medaka shows incomplete conservation of the downstream regulatory network of vertebrate sex determination
    Amaury Herpin
    University of Wuerzburg, Physiological Chemistry, Biocenter, Am Hubland, Wuerzburg, Germany
    Mol Biol Evol 30:2328-46. 2013
  4. pmc Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elements
    Amaury Herpin
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Wurzburg, Germany
    PLoS Genet 6:e1000844. 2010
  5. pmc A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad development
    Amaury Herpin
    Physiological Chemistry I, University of Wurzburg, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    Nucleic Acids Res 37:1510-20. 2009
  6. ncbi Structural and functional evidences for a type 1 TGF-beta sensu stricto receptor in the lophotrochozoan Crassostrea gigas suggest conserved molecular mechanisms controlling mesodermal patterning across bilateria
    A Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, 5008 Bergen, Norway
    Mech Dev 122:695-705. 2005
  7. ncbi Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
    FEBS J 272:3424-40. 2005
  8. ncbi Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes
    Amaury Herpin
    Department of Physiological Chemistry I, University of Wuerzburg, Germany
    FEBS J 274:2977-85. 2007
  9. doi Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance
    Nils Klüver
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    Dev Biol 325:179-88. 2009
  10. ncbi A tolloid homologue from the Pacific oyster Crassostrea gigas
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
    Gene Expr Patterns 7:700-8. 2007

Collaborators

Detail Information

Publications19

  1. pmc Specification of primordial germ cells in medaka (Oryzias latipes)
    Amaury Herpin
    Department of Physiological Chemistry I, University of Wuerzburg, Biozentrum, Am Hubland, D 97074 Wuerzburg, Germany
    BMC Dev Biol 7:3. 2007
    ....
  2. pmc Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bY
    Amaury Herpin
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    BMC Dev Biol 7:99. 2007
    ..This suggested a role for dmrt I bY during male gonad and germ cell development...
  3. pmc Divergent expression regulation of gonad development genes in medaka shows incomplete conservation of the downstream regulatory network of vertebrate sex determination
    Amaury Herpin
    University of Wuerzburg, Physiological Chemistry, Biocenter, Am Hubland, Wuerzburg, Germany
    Mol Biol Evol 30:2328-46. 2013
    ..In summary, these data show that the regulation of the downstream regulatory network of sex determination is less conserved than previously thought. ..
  4. pmc Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elements
    Amaury Herpin
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Wurzburg, Germany
    PLoS Genet 6:e1000844. 2010
    ..In the particular case of dmrt1bY, this contributed to create new hierarchies of sex-determining genes...
  5. pmc A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad development
    Amaury Herpin
    Physiological Chemistry I, University of Wurzburg, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    Nucleic Acids Res 37:1510-20. 2009
    ..The sequence motif was found to be conserved in most of the dmrt1 homologous genes from flies to humans suggesting a widespread conservation of this specific mechanism...
  6. ncbi Structural and functional evidences for a type 1 TGF-beta sensu stricto receptor in the lophotrochozoan Crassostrea gigas suggest conserved molecular mechanisms controlling mesodermal patterning across bilateria
    A Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, 5008 Bergen, Norway
    Mech Dev 122:695-705. 2005
    ..s. pathway in lophotrochozoans...
  7. ncbi Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
    FEBS J 272:3424-40. 2005
    ....
  8. ncbi Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomes
    Amaury Herpin
    Department of Physiological Chemistry I, University of Wuerzburg, Germany
    FEBS J 274:2977-85. 2007
    ....
  9. doi Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance
    Nils Klüver
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
    Dev Biol 325:179-88. 2009
    ..This provides first evidence for a conditional co-regulation of these genes within a transcriptional network...
  10. ncbi A tolloid homologue from the Pacific oyster Crassostrea gigas
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
    Gene Expr Patterns 7:700-8. 2007
    ..The expression of the C. gigas tolloid gene during embryonic and larval development as well as in adult tissues is also explored...
  11. ncbi Divergent expression patterns of Sox9 duplicates in teleosts indicate a lineage specific subfunctionalization
    Nils Klüver
    Department of Physiological Chemistry I, University of Wurzburg, 97074 Wurzburg, Germany
    Dev Genes Evol 215:297-305. 2005
    ..We conclude that Sox9 regulatory subfunctions were not partitioned before divergence of the teleosts and evolved to lineage-specific expression domains...
  12. ncbi Expression of the male determining gene dmrt1bY and its autosomal coorthologue dmrt1a in medaka
    U Hornung
    Department of Physiological Chemistry I, University of Wurzburg, Wurzburg, Germany
    Sex Dev 1:197-206. 2007
    ..These features are consistent with the suggestion that Dmrt1 proteins might function as DNA-binding transcription factors...
  13. ncbi Sequential SDF1a and b-induced mobility guides Medaka PGC migration
    Amaury Herpin
    University of Wuerzburg, Department of Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wuerzburg, Germany
    Dev Biol 320:319-27. 2008
    ..In this process both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs...
  14. doi Molecular mechanisms of sex determination and evolution of the Y-chromosome: insights from the medakafish (Oryzias latipes)
    Amaury Herpin
    University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, Wurzburg, Germany
    Mol Cell Endocrinol 306:51-8. 2009
    ..The molecular mechanisms how dmrt1bY initiates male development are only beginning to be understood, but it is apparent that the dmrt1bY gene functions by inhibiting male primordial germ cell proliferation at the sex-determining stage...
  15. ncbi Gene structure and expression of cg-ALR1, a type I activin-like receptor from the bivalve mollusc Crassostrea gigas
    Amaury Herpin
    Sars International Centre for Marine Molecular Biology, Bergen High Technology Centre, Thormøhlensgt 55, N 5008, Bergen, Norway
    Gene 301:21-30. 2002
    ..To gain insight into evolutionary diversification, phylogenetic analysis as well as an investigation of the genomic structure, including the promoter region of the cgALR1 gene were carried out...
  16. ncbi Molecular characterization of a new leucine-rich repeat-containing G protein-coupled receptor from a bivalve mollusc: evolutionary implications
    Amaury Herpin
    Laboratoire de Biologie et Biotechnologies Marines, IBFA, UMR IFREMER Université de Caen, Physiologie et Ecophysiologie des Mollusques Marins, Esplanade de la Paix, 14032 Caen Cedex, France
    Biochim Biophys Acta 1680:137-44. 2004
    ..A possible involvement in the control of cytological changes occurring in bivalve mollusc digestive gland is discussed...
  17. ncbi Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans
    Amaury Herpin
    Laboratoire de Biologie et Biotechnologies Marines, IBFA, UMR Physiologie et Ecophysiologie des Mollusques Marins IFREMER Université de Caen, Esplanade de la Paix, Caen 14032, France
    Dev Comp Immunol 28:461-85. 2004
    ....
  18. ncbi Characterization of a defensin from the oyster Crassostrea gigas. Recombinant production, folding, solution structure, antimicrobial activities, and gene expression
    Yannick Gueguen
    IFREMER, CNRS, Universite de Montpellier II, UMR 5171, Génome Populations Interactions Adaptation, 2 Place E Bataillon, CC80, F 34095 Montpellier Cedex 5, France
    J Biol Chem 281:313-23. 2006
    ..Our results suggest that Cg-def gene is continuously expressed in the mantle and would play a key role in oyster by providing a first line of defense against pathogen colonization...
  19. ncbi The identification of genes from the oyster Crassostrea gigas that are differentially expressed in progeny exhibiting opposed susceptibility to summer mortality
    Arnaud Huvet
    Unité Mixte de Recherche Physiologie et Ecophysiologie des Mollusques Marins, IFREMER, Centre de Brest, B P 70, 29280 Plouzane, France
    Gene 343:211-20. 2004
    ..This study has identified potential candidates for further investigation into the functional basis of resistance and susceptibility to summer mortality...