Research Topics
Genomes and Genes | A HerpinSummaryCountry: Germany Publications
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Detail Information
Publications
Specification of primordial germ cells in medaka (Oryzias latipes)Amaury Herpin
Department of Physiological Chemistry I, University of Wuerzburg, Biozentrum, Am Hubland, D 97074 Wuerzburg, Germany
BMC Dev Biol 7:3. 2007....
Inhibition of primordial germ cell proliferation by the medaka male determining gene Dmrt I bYAmaury Herpin
University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
BMC Dev Biol 7:99. 2007..This suggested a role for dmrt I bY during male gonad and germ cell development...
Transcriptional rewiring of the sex determining dmrt1 gene duplicate by transposable elementsAmaury Herpin
University of Wurzburg, Physiological Chemistry I, Biozentrum, Wurzburg, Germany
PLoS Genet 6:e1000844. 2010..In the particular case of dmrt1bY, this contributed to create new hierarchies of sex-determining genes...
A highly conserved cis-regulatory motif directs differential gonadal synexpression of Dmrt1 transcripts during gonad developmentAmaury Herpin
Physiological Chemistry I, University of Wurzburg, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
Nucleic Acids Res 37:1510-20. 2009..The sequence motif was found to be conserved in most of the dmrt1 homologous genes from flies to humans suggesting a widespread conservation of this specific mechanism...
Structural and functional evidences for a type 1 TGF-beta sensu stricto receptor in the lophotrochozoan Crassostrea gigas suggest conserved molecular mechanisms controlling mesodermal patterning across bilateriaA Herpin
Sars International Centre for Marine Molecular Biology, High Technology Centre, 5008 Bergen, Norway
Mech Dev 122:695-705. 2005..s. pathway in lophotrochozoans...
Cross-talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell-specific outcomesAmaury Herpin
Department of Physiological Chemistry I, University of Wuerzburg, Germany
FEBS J 274:2977-85. 2007....
Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathwayAmaury Herpin
Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
FEBS J 272:3424-40. 2005....
Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenanceNils Klüver
University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wurzburg, Germany
Dev Biol 325:179-88. 2009..This provides first evidence for a conditional co-regulation of these genes within a transcriptional network...
A tolloid homologue from the Pacific oyster Crassostrea gigasAmaury Herpin
Sars International Centre for Marine Molecular Biology, High Technology Centre, Bergen, Norway
Gene Expr Patterns 7:700-8. 2007..The expression of the C. gigas tolloid gene during embryonic and larval development as well as in adult tissues is also explored...
Divergent expression patterns of Sox9 duplicates in teleosts indicate a lineage specific subfunctionalizationNils Klüver
Department of Physiological Chemistry I, University of Wurzburg, 97074 Wurzburg, Germany
Dev Genes Evol 215:297-305. 2005..We conclude that Sox9 regulatory subfunctions were not partitioned before divergence of the teleosts and evolved to lineage-specific expression domains...
Expression of the male determining gene dmrt1bY and its autosomal coorthologue dmrt1a in medakaU Hornung
Department of Physiological Chemistry I, University of Wurzburg, Wurzburg, Germany
Sex Dev 1:197-206. 2007..These features are consistent with the suggestion that Dmrt1 proteins might function as DNA-binding transcription factors...
Sequential SDF1a and b-induced mobility guides Medaka PGC migrationAmaury Herpin
University of Wuerzburg, Department of Physiological Chemistry I, Biozentrum, Am Hubland, D 97074 Wuerzburg, Germany
Dev Biol 320:319-27. 2008..In this process both SDF1 co-orthologues show only partly overlapping expression pattern and cooperate in the correct positioning of the PGCs...
Molecular mechanisms of sex determination and evolution of the Y-chromosome: insights from the medakafish (Oryzias latipes)Amaury Herpin
University of Wurzburg, Physiological Chemistry I, Biozentrum, Am Hubland, Wurzburg, Germany
Mol Cell Endocrinol 306:51-8. 2009..The molecular mechanisms how dmrt1bY initiates male development are only beginning to be understood, but it is apparent that the dmrt1bY gene functions by inhibiting male primordial germ cell proliferation at the sex-determining stage...
Gene structure and expression of cg-ALR1, a type I activin-like receptor from the bivalve mollusc Crassostrea gigasAmaury Herpin
Sars International Centre for Marine Molecular Biology, Bergen High Technology Centre, , N-5008, Bergen, Norway
Gene 301:21-30. 2002..To gain insight into evolutionary diversification, phylogenetic analysis as well as an investigation of the genomic structure, including the promoter region of the cgALR1 gene were carried out...
Molecular characterization of a new leucine-rich repeat-containing G protein-coupled receptor from a bivalve mollusc: evolutionary implicationsAmaury Herpin
Laboratoire de Biologie et Biotechnologies Marines, IBFA, , Physiologie et Ecophysiologie des Mollusques Marins, Esplanade de la Paix, 14032 Caen Cedex, France
Biochim Biophys Acta 1680:137-44. 2004..A possible involvement in the control of cytological changes occurring in bivalve mollusc digestive gland is discussed...
Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoansAmaury Herpin
Laboratoire de Biologie et Biotechnologies Marines, IBFA, , Esplanade de la Paix, Caen 14032, France
Dev Comp Immunol 28:461-85. 2004....
Characterization of a defensin from the oyster Crassostrea gigas. Recombinant production, folding, solution structure, antimicrobial activities, and gene expressionYannick Gueguen
IFREMER, CNRS, Universite de Montpellier II, UMR 5171, Génome Populations Interactions Adaptation, 2 Place E Bataillon, CC80, F 34095 Montpellier Cedex 5, France
J Biol Chem 281:313-23. 2006..Our results suggest that Cg-def gene is continuously expressed in the mantle and would play a key role in oyster by providing a first line of defense against pathogen colonization...
The identification of genes from the oyster Crassostrea gigas that are differentially expressed in progeny exhibiting opposed susceptibility to summer mortalityArnaud Huvet
Unité Mixte de Recherche Physiologie et Ecophysiologie des Mollusques Marins, IFREMER, Centre de Brest, B P 70, 29280 Plouzane, France
Gene 343:211-20. 2004..This study has identified potential candidates for further investigation into the functional basis of resistance and susceptibility to summer mortality...
