Jochen Huehn

Summary

Affiliation: Helmholtz Centre for Infection Research
Country: Germany

Publications

  1. ncbi Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
    Jochen Huehn
    Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Nat Rev Immunol 9:83-9. 2009
  2. ncbi To be or not to be a Treg cell: lineage decisions controlled by epigenetic mechanisms
    Aras Toker
    Experimental Immunology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany
    Sci Signal 4:pe4. 2011
  3. ncbi Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
    Julia K Polansky
    Experimental Immunology, Helmholtz Centre for Infection Research, Inhoffenstr 7, 38124, Braunschweig, Germany
    J Mol Med (Berl) 88:1029-40. 2010

Collaborators

  • Aras Toker
  • Julia K Polansky
  • Leif Ludwig
  • Melanie Krüger
  • Christoph Thelemann
  • Sascha Cording
  • Lisa Schreiber
  • Stefan Floess
  • Ria Baumgrass
  • Alf Hamann

Detail Information

Publications3

  1. ncbi Epigenetic control of FOXP3 expression: the key to a stable regulatory T-cell lineage?
    Jochen Huehn
    Department of Experimental Immunology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Nat Rev Immunol 9:83-9. 2009
    ....
  2. ncbi To be or not to be a Treg cell: lineage decisions controlled by epigenetic mechanisms
    Aras Toker
    Experimental Immunology, Helmholtz Centre for Infection Research, Inhoffenstrasse 7, 38124 Braunschweig, Germany
    Sci Signal 4:pe4. 2011
    ....
  3. ncbi Methylation matters: binding of Ets-1 to the demethylated Foxp3 gene contributes to the stabilization of Foxp3 expression in regulatory T cells
    Julia K Polansky
    Experimental Immunology, Helmholtz Centre for Infection Research, Inhoffenstr 7, 38124, Braunschweig, Germany
    J Mol Med (Berl) 88:1029-40. 2010
    ..We therefore propose that Ets-1 is part of a larger protein complex, which binds to the TSDR only in its demethylated state, thereby restricting stable Foxp3 expression to the Treg lineage...