Luka Cicin-Sain

Summary

Affiliation: Helmholtz Centre for Infection Research
Country: Germany

Publications

  1. pmc Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts
    Linda Ebermann
    Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 8:e1003062. 2012
  2. pmc Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency
    Franziska Dağ
    Department for Vaccinology Immune Aging and Chronic Infection, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 10:e1003962. 2014
  3. pmc CMV and Immunosenescence: from basics to clinics
    Rafael Solana
    Immunology Unit, Instituto Maimónides de Investigación Biomédica de Córdoba IMIBIC Reina Sofia University Hospital University of Cordoba, Cordoba, Spain
    Immun Ageing 9:23. 2012
  4. pmc Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging
    Luka Cicin-Sain
    Department of Vaccinology and Applied Microbiology, Helmholtz Center for Infection Research, Braunschweig, Germany
    PLoS Pathog 8:e1002849. 2012
  5. doi request reprint The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens
    Iryna Dekhtiarenko
    Department of Vaccinology, Helmholtz Center for Infection Research, Braunschweig 38124, Germany
    J Immunol 190:3399-409. 2013
  6. ncbi request reprint Mouse CMV infection delays antibody class switch upon an unrelated virus challenge
    Thomas F Marandu
    Department of Vaccinology, Helmholtz Centre for Infection Research, Braunschweig, Germany Dar es salaam University College of Education, Tanzania
    Exp Gerontol 54:101-8. 2014
  7. doi request reprint Use of recombinant approaches to construct human cytomegalovirus mutants
    Iryna Dekhtiarenko
    Department of Vaccinology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Methods Mol Biol 1119:59-79. 2014

Collaborators

  • Zsolt Ruzsics
  • Dagmar Wirth
  • Stefan Lienenklaus
  • Barbara Adler
  • Lars Dölken
  • Janko Nikolich-Zugich
  • Iryna Dekhtiarenko
  • Martin Messerle
  • Franziska Dağ
  • Thomas F Marandu
  • Linda Ebermann
  • Rafael Solana
  • Mario Köster
  • Andrea Kröger
  • Adrien Weingärtner
  • Siegfried Weiß
  • Robert Geffers
  • Katja Finsterbusch
  • Ulfert Rand
  • Julia Holzki
  • Anja Drabig
  • Colin Davenport
  • Ianina Conte
  • Johannes Schwerk
  • Hansjorg Hauser
  • Michael A Jarvis
  • Alejandra Pera
  • Anis Larbi
  • Mikko Hurme
  • Sara Cantisán
  • Paul Moss
  • Ulrich Koszinowski
  • Natalie Riddell
  • Jos A Bosch
  • Ann Hill
  • Beatriz Sanchez-Correa
  • Maciej Zielinski
  • Florian Kern
  • Daniela Frasca
  • Nico Van Rooijen
  • Rosaely Casalegno-Garduño
  • Evelyna Derhovanessian
  • Sheila Govind
  • Delphine Sauce
  • Paolo Sansoni
  • Allison E Aiello
  • Beatrix Grubeck-Loebenstein
  • Janet E McElhaney
  • Carmen Campos
  • Mark R Wills
  • Carlos A Guzman
  • Miguel Lopez-Botet
  • Graham Pawelec
  • Rene van Lier
  • Jerrald L Rector
  • Andrea B Maier
  • Arne N Akbar
  • George C Wang
  • Tamas Fulop
  • Raquel Tarazona
  • Mark Beswick
  • Victor Appay
  • Sara Ferrando-Martínez
  • Elissaveta Naumova

Detail Information

Publications7

  1. pmc Block of death-receptor apoptosis protects mouse cytomegalovirus from macrophages and is a determinant of virulence in immunodeficient hosts
    Linda Ebermann
    Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 8:e1003062. 2012
    ....
  2. pmc Reversible silencing of cytomegalovirus genomes by type I interferon governs virus latency
    Franziska Dağ
    Department for Vaccinology Immune Aging and Chronic Infection, Helmholtz Centre for Infection Research, Braunschweig, Germany
    PLoS Pathog 10:e1003962. 2014
    ....
  3. pmc CMV and Immunosenescence: from basics to clinics
    Rafael Solana
    Immunology Unit, Instituto Maimónides de Investigación Biomédica de Córdoba IMIBIC Reina Sofia University Hospital University of Cordoba, Cordoba, Spain
    Immun Ageing 9:23. 2012
    ..Here we summarize the major findings of this workshop...
  4. pmc Cytomegalovirus infection impairs immune responses and accentuates T-cell pool changes observed in mice with aging
    Luka Cicin-Sain
    Department of Vaccinology and Applied Microbiology, Helmholtz Center for Infection Research, Braunschweig, Germany
    PLoS Pathog 8:e1002849. 2012
    ..Therefore, latent MCMV infection resulted in pronounced changes of the T-cell compartment consistent with impaired naïve T-cell function...
  5. doi request reprint The context of gene expression defines the immunodominance hierarchy of cytomegalovirus antigens
    Iryna Dekhtiarenko
    Department of Vaccinology, Helmholtz Center for Infection Research, Braunschweig 38124, Germany
    J Immunol 190:3399-409. 2013
    ....
  6. ncbi request reprint Mouse CMV infection delays antibody class switch upon an unrelated virus challenge
    Thomas F Marandu
    Department of Vaccinology, Helmholtz Centre for Infection Research, Braunschweig, Germany Dar es salaam University College of Education, Tanzania
    Exp Gerontol 54:101-8. 2014
    ..Therefore, our results argue that latent CMV infection impairs B-cell, but not T-cell responses to a challenge with VSV and delays antibody class-switch by a mechanism which may be independent of T-cell help. ..
  7. doi request reprint Use of recombinant approaches to construct human cytomegalovirus mutants
    Iryna Dekhtiarenko
    Department of Vaccinology, Helmholtz Centre for Infection Research, Braunschweig, Germany
    Methods Mol Biol 1119:59-79. 2014
    ..Here we describe the methods used for the generation of a CMV BAC, targeted mutagenesis of BAC clones, and transfection of human cells with CMV BAC DNA in order to reconstitute the viral infection process. ..