Research Topics
Genomes and Genes | S GuniaSummaryAffiliation: HELIOS Klinikum Wuppertal Country: Germany Publications
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Detail Information
Publications
p16(INK4a) is a marker of good prognosis for primary invasive penile squamous cell carcinoma: a multi-institutional studySven Gunia
Institute of Pathology, Helios Clinic Bad Saarow, Bad Saarow, Germany
J Urol 187:899-907. 2012..We assessed the prognostic role of p16(INK4a) expression in penile cancer with respect to cancer specific survival...
Scoring the percentage of Ki67 positive nuclei is superior to mitotic count and the mitosis marker phosphohistone H3 (PHH3) in terms of differentiating flat lesions of the bladder mucosaSven Gunia
Department of Pathology, Helios Clinic Bad Saarow, Bad Saarow, Germany
J Clin Pathol 65:715-20. 2012..To systematically compare different approaches for evaluating mucosal proliferative activity regarding their diagnostic role for delineating flat lesions of the bladder mucosa...
Expression of p53, p21 and cyclin D1 in penile cancer: p53 predicts poor prognosisSven Gunia
Institute of Pathology, Helios Clinic Bad Saarow, Germany
J Clin Pathol 65:232-6. 2012..To evaluate the role of p53, p21 and cyclin D1 expression in patients with penile cancer (PC)...
The FUSE binding proteins FBP1 and FBP3 are potential c-myc regulators in renal, but not in prostate and bladder cancerAchim Weber
Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland
BMC Cancer 8:369. 2008..Whereas it is known that c-myc alterations play a completely different role in various carcinomas of the urogenital tract, the relevance of FBPs is unclear...
Is radical oncosurgery justified for the treatment of primary malignant fibrous histiocytoma of the urinary bladder? Report of two cases and analyses of disease-specific survival rates based on a review of the literatureSven Gunia
Institute of Pathology, Helios Clinic Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, Bad Saarow, Germany
Urol Int 86:261-8. 2011..Advanced studies enrolling a larger number of patients with appropriate clinical and pathological data are needed to compare the beneficial effects of various treatment options...
Knowledge of the anatomical polyp location might bias the pathological classification of histologically equivocal colorectal serrated polyps - a consensus study performed by pathology traineesSven Gunia
Department of Pathology, Helios Clinic Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Street 33, 15526 Bad Saarow, Germany
Pathol Res Pract 207:116-20. 2011....
Lewis(y) antigen (blood group 8, BG8) is a useful marker in the histopathological differential diagnosis of flat urothelial lesions of the urinary bladderSven Gunia
Institute of Pathology, Helios Clinic Bad Saarow, Bad Saarow, Germany
J Clin Pathol 64:672-6. 2011....
Molecular interaction between arsenic hydrate microcrystals and the cell-surface endopeptidase CD10 (neprilysin) - a possible link to the development of renal and cutaneous malignancies upon occupational exposure to arsenic compounds?Sven Gunia
Institute of Pathology, Helios Clinic Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, 15526 Bad Saarow, Germany
Med Hypotheses 75:35-7. 2010....
Expression of CD44s in incidental prostate cancer is more strongly associated with Gleason scores on subsequent radical prostatectomies than conventional prognostic parametersSven Gunia
Department of Pathology, Helios Clinic Bad Saarow, Charité University Medicine Teaching Hospital, DE 15526 Bad Saarow, Germany
Pathobiology 76:286-92. 2009..Recently, expression of CD44s (standard isoform), a transmembranous glycoprotein, has been linked to prognostic outcome in prostate cancer, but its prognostic role in IPC has been neglected so far...
MUC1 expression in incidental prostate cancer predicts staging and grading on the subsequent radical prostatectomySven Gunia
Department of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, Bad Saarow, Germany
Pathol Oncol Res 16:371-5. 2010..This interesting observation clearly awaits validation by larger studies surveying clinical follow-up data...
Expression of prostatic acid phosphatase (PSAP) in transurethral resection specimens of the prostate is predictive of histopathologic tumor stage in subsequent radical prostatectomiesSven Gunia
Department of Pathology, Helios Clinic Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, 15526, Bad Saarow, Germany
Virchows Arch 454:573-9. 2009..Therefore, PSAP might be predictive of tumor stage in IPC and represent a valuable adjunct for clinical decisions in terms of individual therapeutic management...
Impairment of telomeric quadruple helix formation - A possible event involved in the carcinogenicity of aromatic amines from the thermodynamic point of view?Sven Gunia
Institute of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, 15526 Bad Saarow, Germany
Med Hypotheses 75:123-5. 2010....
Digital image analysis of mean AgNOR area objectively discriminates between reactive plasmacytosis and multiple myeloma in cytologic smears from bone marrow aspiratesS Gunia
Institute of Pathology, Helios Clinics Bad Saarow, Charité University Medicine Teaching Hospital, Bad Saarow, Germany
Pathobiology 75:306-11. 2008..To differentiate between reactive plasmacytosis (RP) and multiple myeloma (MM) in bone marrow aspirates by assessment of silver-stainable nucleolar organizer regions (AgNORs)...
Expression of alpha-methylacyl-CoA racemase correlates with histopathologic grading in noninvasive bladder cancerSven Gunia
Department of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, 15526, Bad Saarow, Germany
Virchows Arch 453:165-70. 2008....
Loss of basal cell keratin 14 reflects increased risk of recurrence in surgically resected sinonasal inverted papillomaS Gunia
Department of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Bad Saarow, Germany
J Clin Pathol 61:707-12. 2008....
Ki67 staining index and neuroendocrine differentiation aggravate adverse prognostic parameters in prostate cancer and are characterized by negligible inter-observer variabilitySven Gunia
Department of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Pieskower Strasse 33, 15526 Bad Saarow, Germany
World J Urol 26:243-50. 2008....
Do different disorders in cell cycle regulation account for different biological behavior of urothelial and sinonasal inverted papillomas?S Gunia
Institute of Pathology, HELIOS Klinikum Bad Saarow, Charité University Medicine Teaching Hospital, Bad Saarow, Germany
Pathobiology 75:34-41. 2008..It was the aim of this study to assess the expression of selected cell cycle regulation genes in urothelial and sinonasal inverted papillomas (IP)...
Dural metastases from disseminated prostate cancer clinically mimicking a benign reactive condition of the dura: case report and review of the literatureS Gunia
Department of Pathology, Helios Clinic Bad Saarow, Bad Saarow, Germany sven gunia helios kliniken de
Urol Int 86:239-41. 2011..Therefore, the present case report stresses the notion that very rarely, disseminated PC might present with clinically unsuspected dural metastases radiologically mimicking a benign condition...
Imbalance of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases: a novel approach for explaining the parenchymal liquefaction of the septic spleen?S Gunia
Department of Pathology, Carl Thiem Hospital Cottbus, Berlin Charité Teaching Hospital, Cottbus, Germany
Pathobiology 73:198-204. 2006..Deregulation of this balance is a characteristic of extensive tissue degradation in certain chronic inflammatory diseases...
[How often is bronchopneumonia overlooked as the cause of death in intensive care unit patients?]S Koch
Institut fur Pathologie, HELIOS Klinikum Bad Saarow, Akademisches Lehrkrankenhaus der Charité Universitätsmedizin Berlin, Pieskower Strasse 33, 15526 Bad Saarow, Deutschland
Anaesthesist 57:37-42. 2008..This study addresses the issue of analyzing the relationship between pre-mortem diagnoses and post-mortem findings in an intensive care unit (ICU)...
Mycobacterial spindle cell pseudotumor (MSP) of the nasal septum clinically mimicking Kaposi's sarcoma: case reportS Gunia
Department of Pathology, Carl Thiem Klinikum Cottbus, Cottbus, Germany
Rhinology 43:70-1. 2005....
How far is the preoperative Kattan nomogram applicable for the prediction of recurrence after prostatectomy in patients presenting with PSA levels of more than 20 ng/ml? A validation studyM May
Department of Urology, Carl Thiem Hospital, Cottbus, University Teaching Hospital, Germany
Urol Int 77:222-6. 2006....
[Locally recurrent malignant fibrous histiocytoma of the kidney and spermatic cord]M May
Chirurgische Klinik des Carl Thiem Klinikums Cottbus
Urologe A 43:976-81. 2004..In this study, 26 patients with locally recurrent malignant fibrous histiocytoma of the kidney and spermatic cord after initial R0 resection were reviewed with regard to therapeutic options and prognosis...
[Liposarcoma of the spermatic cord--report of one new case and review of the literature]M May
Klinik für Urologie, Carl Thiem Klinikum Cottbus
Aktuelle Urol 35:130-3. 2004..Retroperitoneal lymphadenectomy does not offer any additional therapeutic benefit, and the role of chemotherapy is not well defined. Regardless of initial therapy, the risk of local recurrence always necessitates long-term followup...
