Research Topics
| O T WolfSummaryAffiliation: Heinrich Heine University Country: Germany Publications
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Detail Information
Publications
Impaired memory retrieval after psychosocial stress in healthy young menSabrina Kuhlmann
Institute of Experimental Psychology, University of Duesseldorf, D-40225 Duesseldorf, Germany
J Neurosci 25:2977-82. 2005..The present study thus demonstrates that psychosocial stress impairs memory retrieval in humans and suggests that emotionally arousing material is especially sensitive to this effect...- Effects of oral cortisol treatment in healthy young women on memory retrieval of negative and neutral wordsSabrina Kuhlmann
Institute of Experimental Psychology, University of Duesseldorf, Germany
Neurobiol Learn Mem 83:158-62. 2005..01), while having no significant effect on neutral words (p=.47). The current findings could suggest that emotional material is especially sensitive to the memory modulating effects of stress hormones... - Volumetric measurement of the hippocampus, the anterior cingulate cortex, and the retrosplenial granular cortex of the rat using structural MRIO T Wolf
Center for Brain Health, Neuroimaging Laboratory, NYU School of Medicine, New York, NY 10016, USA
Brain Res Brain Res Protoc 10:41-6. 2002..93. The current protocol should facilitate future in vivo neuroimaging research using animal models of neurodegenerative diseases... - Endogenous estradiol and testosterone levels are associated with cognitive performance in older women and menOliver T Wolf
Institute of Experimental Psychology II, University of Duesseldorf, Germany
Horm Behav 41:259-66. 2002..In contrast to the positive findings in women endogenous sex steroids do not appear to be closely linked to better cognition in older men... - Cognitive functions and sex steroidsO T Wolf
Institute of Experimental Psychology II, University of Duesseldorf, Geb 23 02, Ebene 01, Raum 43, Universitaetsstrasse 1, D 40225 Duesseldorf, Germany
Ann Endocrinol (Paris) 64:158-61. 2003..Even though most results support the notion that estradiol in women and testosterone in men can enhance cognition in older healthy humans, more research is needed before recommendations for the clinical practice can be made... - HPA axis and memoryO T Wolf
Department of Experimental Psychology II, University of Dusseldorf, Geb 23 02, Ebene 01, Raum 43, Universitatsstrasse 1, D 40225 Dusseldorf, Germany
Best Pract Res Clin Endocrinol Metab 17:287-99. 2003..In humans, similar observations have been reported in several patient populations as well as in older subjects. The potential to reverse these effects using behavioural or pharmacological approaches needs to be explored... - No morning cortisol response in patients with severe global amnesiaOliver T Wolf
Institute of Experimental Psychology, University of Duesseldorf, Geb 23 02, Ebene 01, Room 43, Universitaetsstrasse 1, D 40225 Duesseldorf, Germany
Psychoneuroendocrinology 30:101-5. 2005..Further studies are needed to understand the neurological or psychological mechanisms leading to a missing morning cortisol response in amnesic patients... - Cortisol and memory retrieval in humans: influence of emotional valenceO T Wolf
Department of Experimental Psychology, University of Duesseldorf, Universitaetsstrasse 1, D 40225 Duesseldorf, Germany
Ann N Y Acad Sci 1032:195-7. 2004..Future studies will address these issues, which are of relevance for psychiatric disorders such as posttraumatic stress disorder or major depression... - The relationship between stress induced cortisol levels and memory differs between men and womenO T Wolf
Institute of Experimental Psychology II, University of Duesseldorf, Geb 23 02, Ebene 01, Raum 43, Universitaetsstrasse 1, D 40225, Duesseldorf, Germany
Psychoneuroendocrinology 26:711-20. 2001..Whether these differences reflect activational effects of sex steroids or developmentally-programmed sex differences awaits to be determined... - Estradiol or estradiol/progesterone treatment in older women: no strong effects on cognitionOliver T Wolf
Institute of Experimental Psychology, University of Duesseldorf, Universitaetsstrasse 1, D 40225 Duesseldorf, Germany
Neurobiol Aging 26:1029-33. 2005..The human brain might loose its responsiveness to gonadal steroids with aging or prolonged hormone depletion... - Moderate psychosocial stress appears not to impair recall of words learned 4 weeks prior to stress exposureOliver T Wolf
Institute of Experimental Psychology II, University of Duesseldorf, Duesseldorf, Germany
Stress 5:59-64. 2002..Among them is the small sample size, the moderate cortisol increase in response to the second stress exposure but also the long recall delay, which might lead to memory traces less susceptible to stress... - Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatmentO T Wolf
Center for Brain Health, Neuroimaging Lab, NYU School of Medicine New York, New York, NY 10016, USA
Brain Res 934:87-96. 2002..These data demonstrate a reliable and valid method for the measurement of the rat hippocampus in vivo using MRI with a high field magnet, thereby providing a useful tool for future studies of rodent models of neuro-degenerative diseases... - Cortisol differentially affects memory in young and elderly menO T Wolf
Center for Brain Health, New York University School of Medicine, New York 10016, USA
Behav Neurosci 115:1002-11. 2001..In contrast, Digit Span performance was decreased by cortisol in young but not elderly participants. The possibility that differential age-associated brain changes might underlie the present results is discussed... - A meta-analytic review of the effects of acute cortisol administration on human memoryS Het
Department of Experimental Psychology, University of Duesseldorf, Germany
Psychoneuroendocrinology 30:771-84. 2005..We discuss methodological limitations of the current analysis and suggest several areas for future research... - Hippocampal volume and cognitive performance in long-standing Type 1 diabetic patients without macrovascular complicationsB M Lobnig
Department of Endocrinology, Diabetes and Rheumatology, WHO Collaborating Centre, European Training Centre in Endocrinology and Metabolism, University of Duesseldorf, Germany
Diabet Med 23:32-9. 2006..This is in line with some previous studies in Type 1 diabetes. If replicated in larger studies, our findings would support the idea that the effects on brain function and structure differ between Type 1 and Type 2 diabetes... - MRI volume of the amygdala: a reliable method allowing separation from the hippocampal formationA Convit
Department of Psychiatry, New York University School of Medicine, Aging and Dementia Research Center, NY 10016, USA
Psychiatry Res 90:113-23. 1999..The average amygdala volume was 1.05 +/- 0.17 cm3 on the right and 1.14 +/- 0.15 cm3 on the left. Our amygdala volumes are in agreement with those reported in postmortem studies, which provides the reported method with face validity... 
Prediction of cognitive decline in normal elderly subjects with 2-[(18)F]fluoro-2-deoxy-D-glucose/poitron-emission tomography (FDG/PET)M J de Leon
Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 98:10966-71. 2001..Further study is required to estimate individual risks and to determine the physiologic basis for METglu changes detected while cognition is normal...- Investigating the effects of estradiol or estradiol/progesterone treatment on mood, depressive symptoms, menopausal symptoms and subjective sleep quality in older healthy hysterectomized women: a questionnaire studyA B Heinrich
Institute of Experimental Psychology, University of Dusseldorf, Germany
Neuropsychobiology 52:17-23. 2005..The current small study suggests that older healthy nondepressed hysterectomized women do not react with positive or negative mood changes to estradiol or estradiol/progesterone treatment... - Volumetric analysis of the pre-frontal regions: findings in aging and schizophreniaA Convit
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Psychiatry Res 107:61-73. 2001..No volume differences were observed in the other three regions assessed. Whether or not these volume reductions reflect a common pathological process remains to be investigated in future studies... - Actions of dehydroepiandrosterone and its sulfate in the central nervous system: effects on cognition and emotion in animals and humansO T Wolf
Neuroimaging Laboratory, Department of Psychiatry, NYU School of Medicine, New York, USA
Brain Res Brain Res Rev 30:264-88. 1999..Several reasons for the discrepancy between data obtained in rodents and humans are discussed and research perspectives are outlined which might help to improve interpretation of results obtained in the two species... - Cortisol and memory retrieval in women: influence of menstrual cycle and oral contraceptivesSabrina Kuhlmann
Institute of Experimental Psychology, University of Duesseldorf, Duesseldorf, Germany
Psychopharmacology (Berl) 183:65-71. 2005..The underlying neurobiological mechanisms of these behavioral findings remain to be elucidated... - Subjective memory complaints in aging are associated with elevated cortisol levelsOliver T Wolf
Institute for Experimental Psychology, University of Duesseldorf, Germany
Neurobiol Aging 26:1357-63. 2005..Differences in personality traits or in stress susceptibility might underlie the present findings. Future studies of memory complaints should take a comprehensive approach including relevant endocrine parameters... - No changes in event-related potentials with estrogen or estrogen plus progesterone treatment in healthy older hysterectomized women: results from a double-blind, placebo-controlled studyV Walpurger
Department of Psychoneuroendocrinology, University of Duesseldorf, Universitaetsstrasse 1, 40225, , Germany
Psychopharmacology (Berl) 179:652-61. 2005..The current negative findings might suggest a reduced sensitivity of the aged brain to gonadal steroids... - Salivary cortisol day profiles in elderly with mild cognitive impairmentOliver T Wolf
Center for Brain Health, Neuroimaging Laboratory, New York University School of Medicine, 560 First Avenue, NY, New York 10016, USA
Psychoneuroendocrinology 27:777-89. 2002..Whether cortisol levels, in conjunction with other factors, such as hippocampal volume, will lead to improved prediction of future decline to AD in participants with MCI remains to be established in longitudinal studies... - Effects of the menstrual cycle on auditory event-related potentialsVerena Walpurger
Department of Psychoneuroendocrinology, , , Germany
Horm Behav 46:600-6. 2004..Future ERP studies therefore need to be more attentive to the issue of menstrual phase when studying female subjects or female patients... - Hypothalamic-pituitary-adrenal axis dysregulation and memory impairments in type 2 diabetesHannah Bruehl
Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, New York 10016, USA
J Clin Endocrinol Metab 92:2439-45. 2007..There is evidence of both hypothalamic-pituitary-adrenocortical (HPA) axis and cognitive dysfunction in type 2 diabetes mellitus (T2DM). However, the exact nature and the associations between these abnormalities remain unclear... - Basal hypothalamo-pituitary-adrenal axis activity and corticotropin feedback in young and older men: relationships to magnetic resonance imaging-derived hippocampus and cingulate gyrus volumesOliver T Wolf
Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
Neuroendocrinology 75:241-9. 2002..It remains possible that age-associated changes in fast feedback may be related to changes to other brain sites, such as hypothalamus or pituitary... - Introducing MASC: a movie for the assessment of social cognitionIsabel Dziobek
Center for Brain Health, New York University School of Medicine, New York, NY, USA
J Autism Dev Disord 36:623-36. 2006..Issues pertaining to the multidimensionality of the social cognition construct are discussed... - Knowing what others know, feeling what others feel: a controlled study of empathy in psychotherapistsJason Hassenstab
Department of Psychology, Fordham University, Bronx, New York, USA
J Nerv Ment Dis 195:277-81. 2007..In sum, therapists were better able to interpret the verbal cues of others and described themselves as more emotionally controlled in response to tense interpersonal situations... - A blunted cortisol awakening response and hippocampal atrophy in type 2 diabetes mellitusHannah Bruehl
NYU School of Medicine, Department of Psychiatry, New York, NY 10016, USA
Psychoneuroendocrinology 34:815-21. 2009..Across all subjects, fasting insulin and hippocampal volume were associated with the CAR, independent of diagnosis. Our findings support the hypothesis that hippocampal integrity is an important predictor of the CAR... - Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitusHannah Bruehl
Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Brain Res 1280:186-94. 2009..Thus, obesity and altered cortisol levels may contribute to the impact of T2DM on the hippocampal formation, resulting in decreased verbal declarative memory performance... - Hypercholesterolemia in Asperger syndrome: independence from lifestyle, obsessive-compulsive behavior, and social anxietyIsabel Dziobek
Center for Brain Health, HN 400, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Psychiatry Res 149:321-4. 2007..A potential role for dyslipidemia in the pathogenesis of some forms of autism is discussed... - Who cares? Revisiting empathy in Asperger syndromeKimberley Rogers
Millhauser Laboratories, Center for Brain Health, New York University School of Medicine, New York, NY 10016, USA
J Autism Dev Disord 37:709-15. 2007..Therefore, we propose that the issue of empathy in AS should be revisited... - The 'amygdala theory of autism' revisited: linking structure to behaviorIsabel Dziobek
Center for Brain Health, HN-400, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USA
Neuropsychologia 44:1891-9. 2006..It may, however, be a mediator for narrow interest patterns and the imposition of routines and rituals. Our data, in conjunction with current literature, seem to argue for a modification of the 'amygdala theory of autism'... - Influence of the stress hormone cortisol on fear conditioning in humans: evidence for sex differences in the response of the prefrontal cortexRudolf Stark
Bender Institute of Neuroimaging, University of Giessen, Otto Behaghel Strasse 10F, 35394 Giessen, Germany
Neuroimage 32:1290-8. 2006..In sum, these findings demonstrate that in humans cortisol mostly influences prefrontal brain activation during fear conditioning and that these effects appear to be modulated by sex... - Salivary alpha amylase as marker for adrenergic activity during stress: effect of betablockadeAnda van Stegeren
Department of Clinical Psychology and Cognitive Science Center Amsterdam, University of Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Psychoneuroendocrinology 31:137-41. 2006..The current pharmacological study in the human provides direct evidence for the sensitivity of sAA to changes in adrenergic activation, specifically in reaction to psychological stress... 
Stress, health and ageing: a focus on postmenopausal womenOliver T Wolf
Department of Cognitive Psychology, Ruhr University Bochum, Universitatsstrasse 150, D 44780 Bochum, Germany
Menopause Int 14:129-33. 2008..At the end, the concept of allostatic load (AL) is described, which aims at a broader assessment of the impact of stress on the individual. The strengths and also the current limitations of the AL concept are highlighted...- Salivary alpha amylase and cortisol responses to different stress tasks: impact of sexAnda H van Stegeren
University of Amsterdam, Department of Clinical Psychology and Cognitive Science Center Amsterdam, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Int J Psychophysiol 69:33-40. 2008..Men had higher sAA levels than women during the complete course of the study, but men and women were comparable in their responsivity to the tasks. No strong correlations between sAA and CORT responses were found... - Glucocorticoid therapy-induced memory deficits: acute versus chronic effectsDaniel Coluccia
Department of Psychiatry Research, University of Zurich, 8032 Zurich, Switzerland
J Neurosci 28:3474-8. 2008..Thus, these findings indicate that memory deficits observed under chronically elevated glucocorticoid levels result, at least in part, from acute and reversible glucocorticoid effects on memory retrieval... - Psychosocial stress induces working memory impairments in an n-back paradigmDaniela Schoofs
Department of Cognitive Psychology, Ruhr University Bochum, Universitatsstr 150, D 44780 Bochum, Germany
Psychoneuroendocrinology 33:643-53. 2008..Thus, the effects of stress became smaller the longer the task was performed. Results provide further evidence for impaired working memory after acute stress and illustrate the time course of this phenomenon... - Interaction of endogenous cortisol and noradrenaline in the human amygdalaAnda H van Stegeren
Department of Clinical Psychology and Cognitive Science Center, University of Amsterdam, Roetersstraat 15, 1018 WB, Amsterdam, The Netherlands
Prog Brain Res 167:263-8. 2008..These data support the hypothesis that high endogenous cortisol levels at the time of encoding interact with noradrenergic activation in the amygdala in man... - The influence of stress hormones on emotional memory: relevance for psychopathologyOliver T Wolf
Department of Psychology, University of Bielefeld, Postfach 10 01 31, D 33501 Bielefeld, Germany
Acta Psychol (Amst) 127:513-31. 2008..Finally, the relevance of these findings for emotional memory disturbances in psychiatric disorders is exemplified by discussions on neuroendocrine alterations in depression, post traumatic stress disorder and phobias... - Decision-making and neuroendocrine responses in pathological gamblersKirsten Labudda
Department of Physiological Psychology, University of Bielefeld, P O Box 100131, 33501 Bielefeld, Germany
Psychiatry Res 153:233-43. 2007..Accordingly, the increase of sAA--as an indirect marker of sympathetic nervous system activity--in those patients with less severe decision-making deficits could reflect the use of somatic markers biasing the decision-making process... - Arousal and cortisol interact in modulating memory consolidation in healthy young menSabrina Kuhlmann
Department of Psychology, University of Bielefeld, Bielefeld, Germany
Behav Neurosci 120:217-23. 2006..No effects of cortisol treatment were observed for recognition memory or mood. Results support the notion that glucocorticoids specifically enhance the consolidation of emotional material... - A non-arousing test situation abolishes the impairing effects of cortisol on delayed memory retrieval in healthy womenSabrina Kuhlmann
Department of Psychology, University of Bielefeld, Postfach 100131, D- 33501 Bielefeld, Germany
Neurosci Lett 399:268-72. 2006..84). The results indicate that the experimental setting can influence the effect of cortisol on memory. Our findings suggest that glucocorticoid effects on memory retrieval require testing-associated arousal in humans... - Hypothalamic blood flow correlates positively with stress-induced cortisol levels in subjects with social anxiety disorderFredrik Ahs
Department of Psychology, Uppsala University, Box 1225, SE 751 42 Uppsala, Sweden
Psychosom Med 68:859-62. 2006..Another objective was to evaluate whether salivary cortisol levels correlated with rCBF in other brain areas... - The cortisol awakening response is blunted in psychotherapy inpatients suffering from depressionThomas J Huber
Department of Clinical Psychiatry and Psychotherapy, Medical School Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Psychoneuroendocrinology 31:900-4. 2006..Further studies will be needed to disentangle the complex relationship between depression and the ACR... - Endogenous cortisol level interacts with noradrenergic activation in the human amygdalaAnda H van Stegeren
University of Amsterdam, Department of Clinical Psychology and Cognitive Science Center, Roetersstraat 15, 1018 WB Amsterdam, The Netherlands
Neurobiol Learn Mem 87:57-66. 2007.... - Mood changes in response to psychosocial stress in healthy young women: effects of pretreatment with cortisolSerkan Het
Department of Psychology, University of Bielefeld, Bielefeld, Germany
Behav Neurosci 121:11-20. 2007..Results are discussed with regard to the context of specific adaptive effects of cortisol and the role of cortisol in posttraumatic stress disorder... - Dissociation of cognitive and emotional empathy in adults with Asperger syndrome using the Multifaceted Empathy Test (MET)Isabel Dziobek
Neurocognition of Decision Making, Max Planck Institute for Human Development, Lentzeallee 94, 14195 Berlin, Germany
J Autism Dev Disord 38:464-73. 2008..Internal consistency of the MET's scales ranged from .71 to .92, and convergent and divergent validity were highly satisfactory... - Reduced glucose tolerance is associated with poor memory performance and hippocampal atrophy among normal elderlyAntonio Convit
Center for Brain Health, Department of Psychiatry, New York University School of Medicine, New York, NY 10016, USA
Proc Natl Acad Sci U S A 100:2019-22. 2003..This observation may bring to light a mechanism for aging brain injury that may have substantial medical impact, given the large number of elderly individuals with impaired glucose metabolism...