Melani Simonowska

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. ncbi request reprint Return to work and quality of life after therapy and rehabilitation in oral cancer
    Jörg Handschel
    Deptartment of Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    In Vivo 27:401-7. 2013
  2. doi request reprint Parameters predicting complications in flap surgery
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol 115:589-94. 2013
  3. doi request reprint Psychological aspects affect quality of life in patients with oral squamous cell carcinomas
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Psychooncology 22:677-82. 2013
  4. doi request reprint Tissue expanders for soft tissue reconstruction in the head and neck area--requirements and limitations
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    Clin Oral Investig 17:573-8. 2013
  5. doi request reprint Comparison of various approaches for the treatment of fractures of the mandibular condylar process
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
    J Craniomaxillofac Surg 40:e397-401. 2012
  6. doi request reprint Fear of recurrence significantly influences quality of life in oral cancer patients
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
    Oral Oncol 48:1276-80. 2012
  7. pmc Bilateral multifocal Warthin's tumors in upper neck lymph nodes. Report of a case and brief review of the literature
    Christian Naujoks
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr, 5, D 40225 Dusseldorf, Germany
    Head Face Med 8:11. 2012
  8. ncbi request reprint Intraoral schwannoma: review of the literature and presentation of a rare case
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University of Dusseldorf, Germany
    Cranio 30:150-3. 2012
  9. doi request reprint CT-scan is a valuable tool to detect mandibular involvement in oral cancer patients
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    Oral Oncol 48:361-6. 2012
  10. pmc Embryonic stem cells in scaffold-free three-dimensional cell culture: osteogenic differentiation and bone generation
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr 5, D 40225 Dusseldorf, Germany
    Head Face Med 7:12. 2011

Detail Information

Publications40

  1. ncbi request reprint Return to work and quality of life after therapy and rehabilitation in oral cancer
    Jörg Handschel
    Deptartment of Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstrasse 5, Dusseldorf, Germany
    In Vivo 27:401-7. 2013
    ..Return to work (REW) after cancer treatment is important for both patients and their families and for society in general. For patients it can be a sign of complete recovery and return to normal life...
  2. doi request reprint Parameters predicting complications in flap surgery
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Oral Surg Oral Med Oral Pathol Oral Radiol 115:589-94. 2013
    ..The aim of this prospective study was to determine laboratory parameters predicting complications and/or failure in flap surgery...
  3. doi request reprint Psychological aspects affect quality of life in patients with oral squamous cell carcinomas
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Psychooncology 22:677-82. 2013
    ..Quality of life (QoL) in head and neck cancer patients has been of increasing interest for some years. Unfortunately, only poor data exist regarding the impact of professional psychological support on QoL...
  4. doi request reprint Tissue expanders for soft tissue reconstruction in the head and neck area--requirements and limitations
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    Clin Oral Investig 17:573-8. 2013
    ..Unfortunately, the complication rates for tissue expansion range from 0 to 48 %. Therefore, the purpose of this study was to investigate risk factors for the use of tissue expanders in head and neck reconstructions...
  5. doi request reprint Comparison of various approaches for the treatment of fractures of the mandibular condylar process
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
    J Craniomaxillofac Surg 40:e397-401. 2012
    ..Fractures of the mandibular condyle process are the most common fractures of the lower jaw. Unfortunately, the type of treatment is still a matter of debate...
  6. doi request reprint Fear of recurrence significantly influences quality of life in oral cancer patients
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
    Oral Oncol 48:1276-80. 2012
    ..Interestingly, assessments by doctors sometimes differ from those of patients concerning QoL and level of information. Particularly the probability of cancer recurrence is unclear for many patients...
  7. pmc Bilateral multifocal Warthin's tumors in upper neck lymph nodes. Report of a case and brief review of the literature
    Christian Naujoks
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr, 5, D 40225 Dusseldorf, Germany
    Head Face Med 8:11. 2012
    ..If a primary malignancy can be excluded by a careful staging procedure prior to the operation an isolated excision of the lesions of the neck is the adequate treatment...
  8. ncbi request reprint Intraoral schwannoma: review of the literature and presentation of a rare case
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University of Dusseldorf, Germany
    Cranio 30:150-3. 2012
    ..The treatment of choice is surgical excision. However, malignant schwannomas can also occur, and need a radical resection and a dissection of the regional lymph nodes...
  9. doi request reprint CT-scan is a valuable tool to detect mandibular involvement in oral cancer patients
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    Oral Oncol 48:361-6. 2012
    ..If bone invasion is detected, a mandibulectomy seems always reasonable. In radiologically negative cases histological assessment is necessary to detect mandibular involvement...
  10. pmc Embryonic stem cells in scaffold-free three-dimensional cell culture: osteogenic differentiation and bone generation
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr 5, D 40225 Dusseldorf, Germany
    Head Face Med 7:12. 2011
    ..Further studies will have to show whether the technique is applicable also to pluripotent stem cells of different origin...
  11. pmc Infection, vascularization, remodelling--are stem cells the answers for bone diseases of the jaws?
    Jörg Handschel
    Head Face Med 7:5. 2011
    ..As the classical pharmacological or surgical treatment protocols have only limited success, stem cells might be a promising treatment option, indicated by recently published data...
  12. pmc Osseointegration of zirconia implants compared with titanium: an in vivo study
    Rita Depprich
    Department of Operative and Preventive Dentistry and Endodontics, Heinrich Heine University, Dusseldorf, Germany
    Head Face Med 4:30. 2008
    ....
  13. pmc Desmoplastic fibroma of the mandible--review of the literature and presentation of a rare case
    Michael Schneider
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstr, 5, D 40225 Dusseldorf, Germany
    Head Face Med 5:25. 2009
    ..In this report the actual literature is reviewed regarding epidemiological data, pathology, clinical diagnostic criterias, therapy and prognosis. Moreover, a report of an interesting case is included localized in the mandibular corpus...
  14. pmc Induction of osteogenic markers in differentially treated cultures of embryonic stem cells
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr, 5, 40225 Dusseldorf, Germany
    Head Face Med 4:10. 2008
    ..The purpose of this study was to investigate various supplements in culture media with respect to the induction of osteogenic differentiation...
  15. pmc The extent of the psychological impairment of prosthodontic outpatients at a German University Hospital
    Michelle A Ommerborn
    Department of Operative and Preventive Dentistry and Endodontics, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Head Face Med 4:23. 2008
    ....
  16. pmc Behavior of osteoblastic cells cultured on titanium and structured zirconia surfaces
    Rita Depprich
    Department of Operative and Preventive Dentistry and Endodontics, Heinrich Heine University, Dusseldorf, Germany
    Head Face Med 4:29. 2008
    ..The aim of the present study was to compare osteoblast behavior on structured zirconia and titanium surfaces under standardized conditions...
  17. pmc Ateriovenous subclavia-shunt for head and neck reconstruction
    Rita A Depprich
    Heinrich Heine University Duesseldorf, Department of Cranio and Maxillofacial Surgery, Moorenstr 5, 40225 Duesseldorf, Germany
    Head Face Med 4:27. 2008
    ..Microvascular free flap transfer was performed as a 2-stage procedure two weeks after the shunt operation. The microvascular reconstructive technique is described in detail...
  18. pmc Solitary submucous neurofibroma of the mandible: review of the literature and report of a rare case
    Rita Depprich
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstr 5, D 40225 Dusseldorf, Germany
    Head Face Med 5:24. 2009
    ..Neurofibromas are immunopositive for the S-100 protein, indicating its neural origin. Treatment is surgical and the prognosis is excellent. For illustration a rare case of a solitary neurofibroma in the mandible is presented...
  19. pmc Principles of cartilage tissue engineering in TMJ reconstruction
    Christian Naujoks
    Clinic for Maxillofacial and Plastic Facial Surgery, Westdeutsche Kieferklinik, University of Dusseldorf, Germany
    Head Face Med 4:3. 2008
    ....
  20. pmc Sinus lifting before Le Fort I maxillary osteotomy: a suitable method for oral rehabilitation of edentulous patients with skeletal class-III conditions: review of the literature and report of a case
    Rita A Depprich
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr, 5, 40225 Dusseldorf, Germany
    Head Face Med 3:2. 2007
    ..Functional rehabilitation of patients afflicted with severe mandibular and maxillary alveolar atrophy might be challenging especially in malformed patients...
  21. ncbi request reprint Complications after oral surgery in patients with congenital or drug-induced bleeding disorders
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery of Heinrich Heine University Düsseldorf, Moorenstr 5 Geb 18 73, D 40225 Dusseldorf, Germany
    In Vivo 25:283-6. 2011
    ..Bleeding disorders (BD) can cause significant problems during or after surgical procedures of the oral cavity. The aim of this study was to explore the risk of bleeding following oral surgery in patients with BD...
  22. doi request reprint [Orbital pain from a cranio-maxillofacial surgery perspective]
    J Handschel
    Klinik fur Mund, Kiefer und Plastische Gesichtschirurgie, Heinrich Heine Universitat Dusseldorf, Moorenstr 5, 40225, Dusseldorf, Deutschland
    Ophthalmologe 108:1134-7. 2011
    ..In contrast temporomandibular disorders (TMD) may cause motility disorders and alterations in binocular vision but are not responsible for orbital pain...
  23. doi request reprint The new polyomavirus (MCPyV) does not affect the clinical course in MCCs
    J Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Dusseldorf, Germany
    Int J Oral Maxillofac Surg 39:1086-90. 2010
    ..The survival time was statistically independent from the presence of MCPyV. There is a striking occurrence of MCPyV in MCC, but whether it affects the clinical course remains unclear...
  24. ncbi request reprint Nonvascularized iliac bone grafts for mandibular reconstruction--requirements and limitations
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery of Heinrich Heine University Düsseldorf, Moorenstr 5 Geb 18 73, D 40225 Dusseldorf, Germany
    In Vivo 25:795-9. 2011
    ..The purpose of this study was to describe the treatment outcome with nonvascularized iliac crest grafts over a 10-year period and to determine possible limitations of their use...
  25. pmc Prospects of micromass culture technology in tissue engineering
    Jörg G K Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University Dusseldorf, Moorenstr, 5, 40225 Dusseldorf, Germany
    Head Face Med 3:4. 2007
    ..The purpose of this review is to provide an insight into the fundamentals and the technique of micromass cell culture used to study bone tissue engineering...
  26. ncbi request reprint Cell-based bone reconstruction therapies--cell sources
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr 5 Gebaude 18 73, D 40225 Dusseldorf, Germany
    Int J Oral Maxillofac Implants 21:890-8. 2006
    ..In this review, unrestricted cells, multipotential progenitor cells, determined cells, and genetically modified cells are described systematically, and their advantages as well as limitations are discussed. (More than 50 references.)..
  27. ncbi request reprint Additional use of DNA-image cytometry improves the assessment of resection margins
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Dusseldorf, Germany
    J Oral Pathol Med 36:472-5. 2007
    ..The purpose of this study was to determine the prognostic value of DNA-image cytometry in the assessment of resection margins...
  28. ncbi request reprint [Evaluation of hyperbaric oxygen therapy in treatment of patients with osteomyelitis of the mandible]
    Jörg Handschel
    Klinik für Kiefer und Plastische Gesichtschirurgie, Heinrich Heine Universitat, Moorenstr 5, 40225, Dusseldorf, Germany
    Mund Kiefer Gesichtschir 11:285-90. 2007
    ..Hyperbaric oxygen therapy is one of them. The purpose of this study was to evaluate the clinical outcome of hyperbaric oxygen therapy in these patients...
  29. ncbi request reprint [Medical expert opinions in oral and maxillofacial medicine regarding incisor tooth trauma]
    J Handschel
    Klinik für Kiefer und Plastische Gesichtschirurgie, Heinrich Heine Universitat Dusseldorf, Germany
    Mund Kiefer Gesichtschir 10:14-7. 2006
    ..These traumas are often followed by lawsuits. The aim of this retrospective analysis was to highlight aspects of these lawsuits of special significance and to show the consequences for surgeons and general practitioners...
  30. ncbi request reprint A prospective comparison of octyl-2-cyanoacrylate and suture in standardized facial wounds
    J G K Handschel
    Department of Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstr 5, D 40225 Dusseldorf, Germany
    Int J Oral Maxillofac Surg 35:318-23. 2006
    ....
  31. pmc Adenomatoid odontogenic tumor of the mandible: review of the literature and report of a rare case
    Jörg Gk Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine University, Moorenstr, 5, D 40225 Dusseldorf, Germany
    Head Face Med 1:3. 2005
    ..Immunohistochemically AOT is characterized by positive reactions with certain cytokeratins. Treatment is conservative and the prognosis is excellent. For illustration a rare case of an AOT in the mandible is presented...
  32. ncbi request reprint [Objective assessment of cosmetic outcome of scars]
    J G K Handschel
    Klinik für Kiefer und Plastische Gesichtschirurgie, Heinrich Heine Universitat, Dusseldorf
    Mund Kiefer Gesichtschir 9:396-9. 2005
    ..Cosmetic outcome of surgical treatment in the facial region is influenced by the appearance of the scar. The purpose of this investigation was to evaluate the objectivity and validity of various methods for the assessment of scars...
  33. pmc A histomorphometric meta-analysis of sinus elevation with various grafting materials
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr, 5, D 40225 Dusseldorf, Germany
    Head Face Med 5:12. 2009
    ..Up to now a subject of controversy in maxillofacial surgery and dentistry is, what is the most appropriate graft material for sinus floor augmentation...
  34. doi request reprint Osteogenic differentiation influences stem cell migration out of scaffold-free microspheres
    Fabian Langenbach
    Department for Oral and Maxillofacial Surgery, Heinrich Heine University Hospital of Duesseldorf, Duesseldorf, Germany
    Tissue Eng Part A 16:759-66. 2010
    ..Thus, microspheres could serve as the scaffold and the source of osteogenic cells in future bone regeneration approaches. Further, microspheres permit the precise administration of large amount of cells into an area of interest...
  35. ncbi request reprint Cell-based bone reconstruction therapies-principles of clinical approaches
    Ulrich Meyer
    Department for Cranio and Maxillofacial Surgery, Heinrich Heine Universitat, Moorenstr 5 Gebaude 18 73, D 40225 Disseldorf, Germany
    Int J Oral Maxillofac Implants 21:899-906. 2006
    ..An overview of the basic biological aspects as well as the inherent constraints of different cell-based approaches are given in this paper...
  36. ncbi request reprint Effects of an occlusal splint compared with cognitive-behavioral treatment on sleep bruxism activity
    Michelle A Ommerborn
    Department of Operative and Preventive Dentistry and Endodontics, Faculty of Medicine Heinrich Heine University, Dusseldorf, Germany
    Eur J Oral Sci 115:7-14. 2007
    ..This is an initial attempt to compare CBT and OS in SB patients, and the data collected substantiate the need for further controlled evaluations, using a three-group randomized design with repeated measures to verify treatment effects...
  37. doi request reprint Use of bioreactors in maxillofacial tissue engineering
    Rita Depprich
    Clinic for Maxillofacial and Facial Plastic Surgery, Westdeutsche Kieferklinik, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Br J Oral Maxillofac Surg 46:349-54. 2008
    ..This present review intends to provide an overview of the current state of art in maxillofacial tissue engineering by the use of bioreactors, its limitations and hopes, as well as the future research trends...
  38. pmc Osseointegration of zirconia implants: an SEM observation of the bone-implant interface
    Rita Depprich
    Department for Operative and Preventive Dentistry and Endodontics, Heinrich Heine University Duesseldorf, Germany
    Head Face Med 4:25. 2008
    ..The present study aimed at investigating the osseointegration of zirconia implants with modified ablative surface at an ultrastructural level...
  39. doi request reprint A survey on German dentists regarding the management of craniomandibular disorders
    Michelle Alicia Ommerborn
    Department of Operative and Preventive Dentistry and Endodontics, Faculty of Medicine, Heinrich Heine University, Moorenstr 5, Dusseldorf, Germany
    Clin Oral Investig 14:137-44. 2010
    ..On the basis of the present data, it seems useful to consider intensifying the topic of CMDs and orofacial pain in future undergraduate dental curricula and in postgraduate training...
  40. doi request reprint Compatibility of embryonic stem cells with biomaterials
    Jörg Handschel
    Department for Cranio and Maxillofacial Surgery Heinrich Heine Universität, Moorenstr 5, 40225 Dusseldorf, Germany
    J Biomater Appl 23:549-60. 2009
    ..The gene expression analysis indicates that biomaterials do influence the gene expression of ESCs.Our results provide new insight into the cytocompatibility of ESCs on different scaffolds...