Research Topics
| A SchnitzlerSummaryAffiliation: Heinrich Heine University Country: Germany Publications
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Detail Information
Publications
Synchronised oscillations of the human sensorimotor cortexA Schnitzler
Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
Acta Neurobiol Exp (Wars) 60:271-87. 2000..Thus, investigation of oscillatory sensorimotor activity proceeds from phenomenology to function and provides an interesting approach to address questions in human motor physiology and pathophysiology...
Fluctuations in electrodermal activity reveal variations in single trial brain responses to painful laser stimuli--a fMRI/EEG studyA Mobascher
Department of Psychiatry, Neuropsychiatric Research Laboratory, Heinrich Heine University, Duesseldorf, Germany
Neuroimage 44:1081-92. 2009..Thus, EDA is a useful additional, objective index when pain is studied with fMRI/EEG which might be of particular relevance in the context of genetic- and pharmacoimaging...- Motor impairment in liver cirrhosis without and with minimal hepatic encephalopathyM Butz
Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
Acta Neurol Scand 122:27-35. 2010..Manifest hepatic encephalopathy (HE) goes along with motor symptoms such as ataxia, mini-asterixis, and asterixis. The relevance of motor impairments in cirrhotics without and with minimal HE (mHE) is still a matter of debate... - Mini-asterixis in hepatic encephalopathy induced by pathologic thalamo-motor-cortical couplingL Timmermann
Department of Neurology, Heinrich Heine University, , Germany
Neurology 61:689-92. 2003..HE patients showed thalamo-motor-cortical coupling at a significantly lower frequency than the coupling in control subjects. The pathologic motor cortical drive in HE probably results from altered thalamocortical oscillatory coupling... 
Dynamic imaging of coherent sources: Studying neural interactions in the human brainJ Gross
Department of Neurology, Heinrich-Heine-University, Moorenstrasse 5, D-40225 Duesseldorf, Germany
Proc Natl Acad Sci U S A 98:694-9. 2001....- Task-dependent oscillations during unimanual and bimanual movements in the human primary motor cortex and SMA studied with magnetoencephalographyJ Gross
Department of Neurology, Heinrich-Heine-University, Duesseldorf, Germany
Neuroimage 26:91-8. 2005..In summary, our results indicate a differential functional role of oscillatory activity and coupling in the motor system... - Impaired cerebral oscillatory processing in hepatic encephalopathyL Timmermann
Department of Neurology, University Hospital Cologne, Germany
Clin Neurophysiol 119:265-72. 2008..The present study tested the hypothesis that worsening of motor and sensory symptoms of HE results from a common basic deficit in the cerebral oscillatory processing within the human motor and visual system... - Distinct oscillatory STN-cortical loops revealed by simultaneous MEG and local field potential recordings in patients with Parkinson's diseaseJ Hirschmann
Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
Neuroimage 55:1159-68. 2011..Furthermore, they demonstrate that simultaneous MEG-LFP recordings are a powerful tool to study interactions between brain areas in PD patients undergoing surgery for DBS... - Neuromagnetic correlates of sensorimotor synchronizationK Muller
Heinrich Heine University, Dusseldorf, Germany
J Cogn Neurosci 12:546-55. 2000..This suggests that subjects use mainly sensory feedback in judging and evaluating whether they are "keeping time.".. - Magneto-encephalographic correlates of the lateralized readiness potentialP Praamstra
Department of Neurology, Heinrich Heine Universitat, Dusseldorf, Germany
Brain Res Cogn Brain Res 8:77-85. 1999..MEG thus provides information on the time course of hand-specific motor cortex activation for each hemisphere separately, where the electro-encephalographic LRP provides a composite measure for both hemispheres... - Different cortical organization of visceral and somatic sensation in humansA Schnitzler
Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
Eur J Neurosci 11:305-15. 1999..We propose that this cortical projection pattern forms the neurophysiological basis of the low temporal and spatial resolution of conscious visceral sensation... - Involvement of the motor cortex in pseudochoreoathetosisL Timmermann
Department of Neurology, Heinrich-Heine University, Duesseldorf, Germany
Mov Disord 16:876-81. 2001..The enhanced MEG-EMG coherence in pseudochoreoathetosis probably reflects a pathologically strong motor cortical drive of spinal motorneurons after deafferentation... - Neurophysiology and functional neuroanatomy of pain perceptionA Schnitzler
Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
J Clin Neurophysiol 17:592-603. 2000..The authors review the evidence on which the proposed relationship between cortical areas, pain-related neural activations, and components of pain perception is based... - Subtype-specific statistical causalities in parkinsonian tremorE Florin
Department of Neurology, University Hospital Cologne, Kerpener Strasse 62, 50937 Koln, Germany
Neuroscience 210:353-62. 2012..Therefore, we hypothesize different pathophysiological mechanisms to underlie the generation of tremor in the two subtypes of Parkinson's disease... - Properties of MEG tomographic maps obtained with spatial filteringJ Gross
Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D 40225 Duesseldorf, Germany
Neuroimage 19:1329-36. 2003..It is important for assigning local maxima of activation to specific anatomical structures and may be used to test for differences in localization between different experimental conditions... - Differential coding of pain intensity in the human primary and secondary somatosensory cortexL Timmermann
Department of Neurology, Heinrich-Heine-University, Moorenstrasse 5, 40225 Dusseldorf, Germany
J Neurophysiol 86:1499-503. 2001..Instead, SII may subserve recognition of the noxious nature and attention toward painful stimuli... - The neural basis of intermittent motor control in humansJ Gross
Department of Neurology, Heinrich Heine University, D-40225 Duesseldorf, Germany
Proc Natl Acad Sci U S A 99:2299-302. 2002..Our findings suggest that coupling of 6- to 9-Hz oscillatory activity in the cerebello-thalamo-cortical loop represents the neural mechanism for the intermittent control of continuous movements... - Laser-evoked potential P2 single-trial amplitudes covary with the fMRI BOLD response in the medial pain system and interconnected subcortical structuresA Mobascher
Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
Neuroimage 45:917-26. 2009..Furthermore, our findings suggest a concerted effort of the ACC and the amygdala in the cognitive-emotional evaluation of pain... - Enlargement of a chronic aseptic lumbar epidural abscess by intraspinal injections--a rare cause of progressive paraparesisM Sabel
Department of Neurosurgery, Heinrich Heine University, Dusseldorf
Zentralbl Neurochir 61:111-4. 2000..Though we present a very rare cause of such complications, a careful monitoring of the neurological status of the patient is necessary as well as the early application of MR imaging in the case of deterioration... - Pathological oscillatory coupling within the human motor system in different tremor syndromes as revealed by magnetoencephalographyL Timmermann
Department of Neurology and Gastroenterology, University Hospital Dusseldorf, Germany
Neurol Clin Neurophysiol 2004:26. 2004..However, the present study shows different mechanisms of tremor generation in PD and HE patients... - Tactile information from the human hand reaches the ipsilateral primary somatosensory cortexA Schnitzler
Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland
Neurosci Lett 200:25-8. 1995..This interhemispheric information transfer may represent a neurophysiological substrate of somatosensory fusion between the hands... - [Cortical representation of pain]M Ploner
Neurologische Klinik, Heinrich Heine Universitat, Dusseldorf
Nervenarzt 75:962-9. 2004..Furthermore, first pain appears to be particularly related to activation of S1 whereas second pain is closely related to ACC activation... - [Early deep brain stimulation for Parkinson's disease]A Schnitzler
Zentrum für Bewegungsstörungen und Neuromodulation der Neurologischen Klinik, Institut für Klinische Neurowissenschaften und Medizinische Psychologie, Universitätsklinikum der Heinrich Heine Universität Düsseldorf, Dusseldorf
Fortschr Neurol Psychiatr 78:S37-40. 2010.... - Motor impairment in patients with parietal lesions: disturbances of meaningless arm movement sequencesP H Weiss
Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
Neuropsychologia 39:397-405. 2001..These results demonstrate that lesions in the left parietal lobe lead to a disturbed spatio-temporal organisation of movement that becomes increasingly prominent for more complex movements... - Local Lyapunov exponents detect epileptic zones in spike-less interictal MEG recordingsZ J Kowalik
Department of Neurology, Heinrich Heine University Dusseldorf, Moorenstrasse 5, D 40225, Dusseldorf, Germany
Clin Neurophysiol 112:60-7. 2001..We explored whether such a multistability is reflected also in the dynamical characteristics of the interictal signal... - Motor-cortical oscillations in early stages of Parkinson's diseaseB Pollok
University of Dusseldorf, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology, Department of Neurology, Dusseldorf, Germany
J Physiol 590:3203-12. 2012..The present results suggest that the reduced ability of the primary motor cortex to disengage from increased beta band oscillations during the execution of movements is an early marker of PD... - Transcallosally mediated inhibition of interneurons within human primary motor cortexA Schnitzler
Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
Exp Brain Res 112:381-91. 1996.... - Early-onset multisystem degeneration with central motor, autonomic and optic nerve disturbances: unusual Riley-Day syndrome or new clinical entity?A Schnitzler
Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
J Neurol Sci 154:205-8. 1998..We consider this syndrome a slowly progressive multisystemic degeneration with two unusual hitherto unreported features: the combination of affected systems (autonomic and motor systems, optic nerves), and the early onset... - Cortical origin of mini-asterixis in hepatic encephalopathyL Timmermann
Department of Neurology, Heinrich-Heine-University, , Germany
Neurology 58:295-8. 2002..The corticomuscular coupling demonstrates the involvement of M1 in asterixis and may reflect a pathologically slowed and synchronized motor cortical drive... - Use-dependent cortical plasticity in thalidomide-induced upper extremity dysplasia: evidence from somaesthesia and neuroimagingM C Stoeckel
Department of Neurology, University Hospital Dusseldorf, Dusseldorf, Germany
Exp Brain Res 156:333-41. 2004.... - Observation of a finger or an object movement primes imitative responses differentiallyM Jonas
Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
Exp Brain Res 177:255-65. 2007..Thus, S1 immediately elicits an imitative response tendency. As an overt imitation of S1 is inadequate in the present setting, the response is inhibited which, in turn, modulates congruency effects... - Deep brain stimulation in Parkinson's diseaseS J Groiss
Department of Neurology, Center for Movement Disorders and Neuromodulation, Heinrich Heine University of Dusseldorf, Germany, Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University of Dusseldorf, Germany
Ther Adv Neurol Disord 2:20-8. 2009..It is presently investigated whether the optimal timing for implantation may be at an earlier disease-stage to prevent psychosocial decline and to maintain quality of life for a longer period of time... - [Psychobehavioural assessment for chronic low back pain]F Genet
Service de Medecine Physique et de Readaptation, groupe hospitalier Raymond Poincaré, hôpital maritime de Berck, 104 boulevard Raymond Poincaré, 92380 Garches, France
Ann Readapt Med Phys 49:226-33. 2006..Psychobehavioural assessment may be a complementary approach to assess response to treatment for pain and disability in patients with low back pain... - Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonismE Moro
Movement Disorder Centre, Toronto Western Hospital, University of Toronto, Ontario, Canada
Neurology 70:1186-91. 2008.... - Multicenter study on deep brain stimulation in Parkinson's disease: an independent assessment of reported adverse events at 4 yearsMarwan I Hariz
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, Queen Square, London, United Kingdom
Mov Disord 23:416-21. 2008..When comparing patients who exhibited AEs with those who did not, it was found that in the STN DBS group, the patients with AEs had a longer disease duration, as well as more gait disorders and psychiatric disturbances at baseline... - Do simple intransitive finger movements consistently activate frontoparietal mirror neuron areas in humans?M Jonas
NeuroImage Nord, Hamburg Kiel Lübeck, Germany
Neuroimage 36:T44-53. 2007..We propose that the responsiveness of human frontoparietal mirror neuron areas to simple intransitive movements critically depends on the experimental context...