A Schnitzler

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. pmc Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease
    Ariane Keitel
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany
    PLoS ONE 8:e81878. 2013
  2. pmc Modulation of human time processing by subthalamic deep brain stimulation
    Lars Wojtecki
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
    PLoS ONE 6:e24589. 2011
  3. pmc The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation
    Arian Mobascher
    Department of Psychiatry, Johannes Gutenberg University, Untere Zahlbacher Str 8, 55131, Germany
    Mol Pain 6:32. 2010
  4. ncbi request reprint Pain facilitates tactile processing in human somatosensory cortices
    Markus Ploner
    Dept of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    J Neurophysiol 92:1825-9. 2004
  5. ncbi request reprint Normal and pathological oscillatory communication in the brain
    Alfons Schnitzler
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Nat Rev Neurosci 6:285-96. 2005
  6. ncbi request reprint Physiological and pathological oscillatory networks in the human motor system
    Alfons Schnitzler
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    J Physiol Paris 99:3-7. 2006
  7. ncbi request reprint Synchronized brain network associated with essential tremor as revealed by magnetoencephalography
    Alfons Schnitzler
    Department of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 24:1629-35. 2009
  8. ncbi request reprint High compliance with rotigotine transdermal patch in the treatment of idiopathic Parkinson's disease
    Alfons Schnitzler
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Universitatsstr 1, Dusseldorf, Germany
    Parkinsonism Relat Disord 16:513-6. 2010
  9. ncbi request reprint Neurophysiology and functional neuroanatomy of pain perception
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    J Clin Neurophysiol 17:592-603. 2000
  10. doi request reprint Differential modulation of STN-cortical and cortico-muscular coherence by movement and levodopa in Parkinson's disease
    J Hirschmann
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Neuroimage 68:203-13. 2013

Collaborators

Detail Information

Publications111 found, 100 shown here

  1. pmc Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease
    Ariane Keitel
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University, Duesseldorf, Germany
    PLoS ONE 8:e81878. 2013
    ..The present findings underscore the potency of patients' expectation and its relevance for therapeutic outcomes. ..
  2. pmc Modulation of human time processing by subthalamic deep brain stimulation
    Lars Wojtecki
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
    PLoS ONE 6:e24589. 2011
    ..Our results corroborate the involvement of BG in general and of the STN in particular in the cognitive representation of time intervals in the range of multiple seconds...
  3. pmc The val158met polymorphism of human catechol-O-methyltransferase (COMT) affects anterior cingulate cortex activation in response to painful laser stimulation
    Arian Mobascher
    Department of Psychiatry, Johannes Gutenberg University, Untere Zahlbacher Str 8, 55131, Germany
    Mol Pain 6:32. 2010
    ..In the present fMRI study we therefore sought to investigate the impact of the COMT val158met polymorphism on the blood oxygen level-dependent (BOLD) response to painful laser stimulation...
  4. ncbi request reprint Pain facilitates tactile processing in human somatosensory cortices
    Markus Ploner
    Dept of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    J Neurophysiol 92:1825-9. 2004
    ..Thus these findings may represent a physiological correlate of an alerting function of pain as a change in the internal state to prepare for processing signals of particular relevance...
  5. ncbi request reprint Normal and pathological oscillatory communication in the brain
    Alfons Schnitzler
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Nat Rev Neurosci 6:285-96. 2005
    ..mechanisms that govern local and long-range communication and how do they relate to the structure of the brain? How does oscillatory synchronization subserve neural communication? And what are the consequences of abnormal synchronization?..
  6. ncbi request reprint Physiological and pathological oscillatory networks in the human motor system
    Alfons Schnitzler
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    J Physiol Paris 99:3-7. 2006
    ..In conclusion, the analysis of oscillatory cerebral networks provides new insights into physiological mechanisms of motor control and pathophysiological mechanisms of tremor disorders...
  7. ncbi request reprint Synchronized brain network associated with essential tremor as revealed by magnetoencephalography
    Alfons Schnitzler
    Department of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 24:1629-35. 2009
    ..These results are consistent with the view that in ET, a network of cerebral areas including brainstem shows oscillatory interactions, which lead to a rhythmic modulation of muscle activity becoming apparent as tremor...
  8. ncbi request reprint High compliance with rotigotine transdermal patch in the treatment of idiopathic Parkinson's disease
    Alfons Schnitzler
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Universitatsstr 1, Dusseldorf, Germany
    Parkinsonism Relat Disord 16:513-6. 2010
    ..This open, prospective, non-interventional study investigated compliance with the patch under clinical practice conditions...
  9. ncbi request reprint Neurophysiology and functional neuroanatomy of pain perception
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    J Clin Neurophysiol 17:592-603. 2000
    ..The authors review the evidence on which the proposed relationship between cortical areas, pain-related neural activations, and components of pain perception is based...
  10. doi request reprint Differential modulation of STN-cortical and cortico-muscular coherence by movement and levodopa in Parkinson's disease
    J Hirschmann
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Neuroimage 68:203-13. 2013
    ..We conclude that they represent partly independent sub-loops within the motor system. Given their negative correlation with akinesia, neither can be considered "antikinetic"...
  11. doi request reprint Does increased gamma activity in patients suffering from Parkinson's disease counteract the movement inhibiting beta activity?
    E Florin
    Department of Neurology, University Hospital Cologne, Kerpener Strasse 62, 50937 Koln, Germany
    Neuroscience 237:42-50. 2013
    ..We hypothesise that in order to enable repetitive fist movement despite increased beta activity, "prokinetic" gamma activity may be increased as a compensatory mechanism...
  12. ncbi request reprint Impaired cerebral oscillatory processing in hepatic encephalopathy
    L Timmermann
    Department of Neurology, University Hospital Cologne, Germany
    Clin Neurophysiol 119:265-72. 2008
    ..The present study tested the hypothesis that worsening of motor and sensory symptoms of HE results from a common basic deficit in the cerebral oscillatory processing within the human motor and visual system...
  13. doi request reprint Motor impairment in liver cirrhosis without and with minimal hepatic encephalopathy
    M Butz
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Dusseldorf, Germany
    Acta Neurol Scand 122:27-35. 2010
    ..Manifest hepatic encephalopathy (HE) goes along with motor symptoms such as ataxia, mini-asterixis, and asterixis. The relevance of motor impairments in cirrhotics without and with minimal HE (mHE) is still a matter of debate...
  14. doi request reprint Fluctuations in electrodermal activity reveal variations in single trial brain responses to painful laser stimuli--a fMRI/EEG study
    A Mobascher
    Department of Psychiatry, Neuropsychiatric Research Laboratory, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 44:1081-92. 2009
    ..Thus, EDA is a useful additional, objective index when pain is studied with fMRI/EEG which might be of particular relevance in the context of genetic- and pharmacoimaging...
  15. ncbi request reprint Task-dependent oscillations during unimanual and bimanual movements in the human primary motor cortex and SMA studied with magnetoencephalography
    J Gross
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 26:91-8. 2005
    ..In summary, our results indicate a differential functional role of oscillatory activity and coupling in the motor system...
  16. ncbi request reprint Mini-asterixis in hepatic encephalopathy induced by pathologic thalamo-motor-cortical coupling
    L Timmermann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Neurology 61:689-92. 2003
    ..HE patients showed thalamo-motor-cortical coupling at a significantly lower frequency than the coupling in control subjects. The pathologic motor cortical drive in HE probably results from altered thalamocortical oscillatory coupling...
  17. pmc Dynamic imaging of coherent sources: Studying neural interactions in the human brain
    J Gross
    Department of Neurology, Heinrich-Heine-University, Moorenstrasse 5, D-40225 Duesseldorf, Germany
    Proc Natl Acad Sci U S A 98:694-9. 2001
    ....
  18. ncbi request reprint The cerebral oscillatory network of parkinsonian resting tremor
    Lars Timmermann
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Brain 126:199-212. 2003
    ..The main frequency of cerebro-cerebral coupling corresponds to double the tremor frequency...
  19. doi request reprint Source analysis of median nerve stimulated somatosensory evoked potentials and fields using simultaneously measured EEG and MEG signals
    K G Mideksa
    Department of Neurology, Christian Albrechts University, Kiel 24105, Germany
    Conf Proc IEEE Eng Med Biol Soc 2012:4903-6. 2012
    ..For CDR analysis, it looks like MEG affects EEG during the combined analyses. The MUSIC algorithm gives better results than CDR, and when comparing the two head models, the averaged and the realistic head models showed the same result...
  20. doi request reprint Distinct oscillatory STN-cortical loops revealed by simultaneous MEG and local field potential recordings in patients with Parkinson's disease
    J Hirschmann
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Neuroimage 55:1159-68. 2011
    ..Furthermore, they demonstrate that simultaneous MEG-LFP recordings are a powerful tool to study interactions between brain areas in PD patients undergoing surgery for DBS...
  21. pmc Motor-cortical oscillations in early stages of Parkinson's disease
    B Pollok
    University of Dusseldorf, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology, Department of Neurology, Dusseldorf, Germany
    J Physiol 590:3203-12. 2012
    ..The present results suggest that the reduced ability of the primary motor cortex to disengage from increased beta band oscillations during the execution of movements is an early marker of PD...
  22. ncbi request reprint Different cortical organization of visceral and somatic sensation in humans
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Eur J Neurosci 11:305-15. 1999
    ..We propose that this cortical projection pattern forms the neurophysiological basis of the low temporal and spatial resolution of conscious visceral sensation...
  23. doi request reprint Characterisation of tremor-associated local field potentials in the subthalamic nucleus in Parkinson's disease
    Christiane Reck
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Eur J Neurosci 29:599-612. 2009
    ..These findings suggest the existence of distribution- and muscle-specific tremor-associated LFP activity at different tremor frequencies and an organisation of tremor-related subloops within the STN...
  24. ncbi request reprint Magneto-encephalographic correlates of the lateralized readiness potential
    P Praamstra
    Department of Neurology, Heinrich Heine Universitat, Dusseldorf, Germany
    Brain Res Cogn Brain Res 8:77-85. 1999
    ..MEG thus provides information on the time course of hand-specific motor cortex activation for each hemisphere separately, where the electro-encephalographic LRP provides a composite measure for both hemispheres...
  25. ncbi request reprint Involvement of the motor cortex in pseudochoreoathetosis
    L Timmermann
    Department of Neurology, Heinrich-Heine University, Duesseldorf, Germany
    Mov Disord 16:876-81. 2001
    ..The enhanced MEG-EMG coherence in pseudochoreoathetosis probably reflects a pathologically strong motor cortical drive of spinal motorneurons after deafferentation...
  26. ncbi request reprint The cerebral oscillatory network associated with auditorily paced finger movements
    Bettina Pollok
    Department of Neurology, MEG Laboratory, Heinrich Heine University, Moorenstr 5, 40225 Duesseldorf, Germany
    Neuroimage 24:646-55. 2005
    ....
  27. ncbi request reprint Cortical mechanisms of attention in time: neural correlates of the Lag-1-sparing phenomenon
    Klaus Kessler
    MEG Laboratory, Department of Neurology, Heinrich Heine University, Moorenstr 5, Duesseldorf 40225, Germany
    Eur J Neurosci 21:2563-74. 2005
    ..e. masks), yet identified targets are processed and consolidated as two separate events by other cortical areas (right TPF and PFC, respectively)...
  28. ncbi request reprint Functional connectivity analysis in magnetoencephalography
    Alfons Schnitzler
    Department of Neurology, MEG, Heinrich Heine University 40225 Duesseldorf, Germany
    Int Rev Neurobiol 68:173-95. 2005
  29. ncbi request reprint Evoked response amplitudes from somatosensory cortices do not determine reaction times to tactile stimuli
    Markus Ploner
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Eur J Neurosci 25:3734-41. 2007
    ..Moreover, our results show that amplitudes of evoked responses from somatosensory cortices do not determine reaction times to tactile stimuli...
  30. pmc The cerebral oscillatory network of voluntary tremor
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Duesseldorf, Germany
    J Physiol 554:871-8. 2004
    ..Thus, our data are consistent with the hypothesis that parkinsonian resting tremor involves oscillatory cerebro-cerebral coupling in a physiologically pre-existing network...
  31. doi request reprint Effects of 10 Hz and 20 Hz transcranial alternating current stimulation (tACS) on motor functions and motor cortical excitability
    C Wach
    Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University, Universitaetsstr 1, 40225 Duesseldorf, Germany
    Behav Brain Res 241:1-6. 2013
    ..The present findings suggest differential effects of stimulation frequency on motor behaviour and M1 excitability...
  32. ncbi request reprint Neuromagnetic correlates of sensorimotor synchronization
    K Muller
    Heinrich Heine University, Dusseldorf, Germany
    J Cogn Neurosci 12:546-55. 2000
    ..This suggests that subjects use mainly sensory feedback in judging and evaluating whether they are "keeping time."..
  33. ncbi request reprint Differential coding of pain intensity in the human primary and secondary somatosensory cortex
    L Timmermann
    Department of Neurology, Heinrich-Heine-University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    J Neurophysiol 86:1499-503. 2001
    ..Instead, SII may subserve recognition of the noxious nature and attention toward painful stimuli...
  34. ncbi request reprint Properties of MEG tomographic maps obtained with spatial filtering
    J Gross
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, D 40225 Duesseldorf, Germany
    Neuroimage 19:1329-36. 2003
    ..It is important for assigning local maxima of activation to specific anatomical structures and may be used to test for differences in localization between different experimental conditions...
  35. ncbi request reprint Bimanual coordination: neuromagnetic and behavioral data
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Moorenstr 5, 40225, Dusseldorf, Germany
    Neuroreport 15:449-52. 2004
    ..Since we found no differences of amplitudes or latencies of corresponding sources of both hemispheres, our data suggest that dominance of the left motor cortex is not a fundamental characteristic for bimanual coordination...
  36. ncbi request reprint Synchronized brain network underlying postural tremor in Wilson's disease
    Martin Südmeyer
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 21:1935-40. 2006
    ..Taken together, our results indicate that WD postural tremor is generated within a synchronized cerebello-thalamo-cortical network, comprising S1/M1, higher cortical motor areas (SMA, PM), and PPC...
  37. ncbi request reprint Ten-Hertz stimulation of subthalamic nucleus deteriorates motor symptoms in Parkinson's disease
    Lars Timmermann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 19:1328-33. 2004
    ..This finding indicates the clinical relevance of pathological 10 Hz synchronization in PD...
  38. doi request reprint Causality between local field potentials of the subthalamic nucleus and electromyograms of forearm muscles in Parkinson's disease
    Esther Florin
    Department of Neurology, University Hospital Cologne, Koln, Germany
    Eur J Neurosci 31:491-8. 2010
    ..Therefore, the effect of deep brain stimulation in the subthalamic nucleus could, at least in part, result from a blockade of pathological afferent input...
  39. doi request reprint Altered pattern of motor cortical activation-inhibition during voluntary movements in Tourette syndrome
    Stephanie Franzkowiak
    Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Duesseldorf, Germany
    Mov Disord 25:1960-6. 2010
    ..The stronger this inhibition is, the better symptoms appear to be controlled...
  40. doi request reprint Subtype-specific statistical causalities in parkinsonian tremor
    E Florin
    Department of Neurology, University Hospital Cologne, Kerpener Strasse 62, 50937 Koln, Germany
    Neuroscience 210:353-62. 2012
    ..Therefore, we hypothesize different pathophysiological mechanisms to underlie the generation of tremor in the two subtypes of Parkinson's disease...
  41. ncbi request reprint Synchronised oscillations of the human sensorimotor cortex
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Acta Neurobiol Exp (Wars) 60:271-87. 2000
    ..Thus, investigation of oscillatory sensorimotor activity proceeds from phenomenology to function and provides an interesting approach to address questions in human motor physiology and pathophysiology...
  42. ncbi request reprint The oscillatory network of simple repetitive bimanual movements
    Bettina Pollok
    Department of Neurology, MEG Laboratory, Heinrich Heine University, 40225 Duesseldorf, Germany
    Brain Res Cogn Brain Res 25:300-11. 2005
    ..Most importantly, our data indicate strong coupling between both cerebellar hemispheres substantiating the hypothesis that cerebellar signals might be integrated during task execution...
  43. ncbi request reprint Perception in action: the impact of sensory information on sensorimotor synchronization in musicians and non-musicians
    Vanessa Krause
    Institute for Clinical Neuroscience and Medical Psychology, Heinrich Heine University, Duesseldorf, Germany Department of Neurology, University Hospital Duesseldorf, Germany
    Acta Psychol (Amst) 133:28-37. 2010
    ..Since particularly synchronization variability was affected by musical expertise, the present data imply that the type of instrument improves accuracy of timekeeping mechanisms...
  44. ncbi request reprint Studying the human somatosensory hand area: A new way to compare fMRI and MEG
    Maria Cornelia Stoeckel
    Department of Neurology, University Hospital Dusseldorf, Moorenstr 5, 40225 Dusseldorf, Germany
    J Neurosci Methods 164:280-91. 2007
    ..Our study demonstrates how relative localization of somatosensory activations can serve as an indicator for localization validity when comparing different methods or studying somatosensory plasticity...
  45. ncbi request reprint Oscillatory coupling in writing and writer's cramp
    Markus Butz
    Department of Neurology, MEG Laboratory, Heinrich Heine University, Moorenstr 5, D 40225 Dusseldorf, Germany
    J Physiol Paris 99:14-20. 2006
    ..These results are consistent with the often described bilateral pathophysiology and impaired sensorimotor integration in writer's cramp patients...
  46. doi request reprint Differential distribution of coherence between beta-band subthalamic oscillations and forearm muscles in Parkinson's disease during isometric contraction
    Christiane Reck
    Department of Neurology, University Hospital Cologne, Cologne, Germany
    Clin Neurophysiol 120:1601-9. 2009
    ..However, the beta-band coupling between STN and muscle activity, its distribution and relation to motor symptoms remains unclear...
  47. ncbi request reprint Motor impairment in patients with parietal lesions: disturbances of meaningless arm movement sequences
    P H Weiss
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Neuropsychologia 39:397-405. 2001
    ..These results demonstrate that lesions in the left parietal lobe lead to a disturbed spatio-temporal organisation of movement that becomes increasingly prominent for more complex movements...
  48. doi request reprint Laser-evoked potential P2 single-trial amplitudes covary with the fMRI BOLD response in the medial pain system and interconnected subcortical structures
    A Mobascher
    Department of Psychiatry, Heinrich Heine University, Duesseldorf, Germany
    Neuroimage 45:917-26. 2009
    ..Furthermore, our findings suggest a concerted effort of the ACC and the amygdala in the cognitive-emotional evaluation of pain...
  49. ncbi request reprint Cortical origin of mini-asterixis in hepatic encephalopathy
    L Timmermann
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Neurology 58:295-8. 2002
    ..The corticomuscular coupling demonstrates the involvement of M1 in asterixis and may reflect a pathologically slowed and synchronized motor cortical drive...
  50. pmc The neural basis of intermittent motor control in humans
    J Gross
    Department of Neurology, Heinrich Heine University, D 40225 Duesseldorf, Germany
    Proc Natl Acad Sci U S A 99:2299-302. 2002
    ..Our findings suggest that coupling of 6- to 9-Hz oscillatory activity in the cerebello-thalamo-cortical loop represents the neural mechanism for the intermittent control of continuous movements...
  51. ncbi request reprint Use-dependent cortical plasticity in thalidomide-induced upper extremity dysplasia: evidence from somaesthesia and neuroimaging
    M C Stoeckel
    Department of Neurology, University Hospital Dusseldorf, Dusseldorf, Germany
    Exp Brain Res 156:333-41. 2004
    ....
  52. ncbi request reprint Pathological oscillatory coupling within the human motor system in different tremor syndromes as revealed by magnetoencephalography
    L Timmermann
    Department of Neurology and Gastroenterology, University Hospital Dusseldorf, Germany
    Neurol Clin Neurophysiol 2004:26. 2004
    ..However, the present study shows different mechanisms of tremor generation in PD and HE patients...
  53. ncbi request reprint Tactile information from the human hand reaches the ipsilateral primary somatosensory cortex
    A Schnitzler
    Low Temperature Laboratory, Helsinki University of Technology, Espoo, Finland
    Neurosci Lett 200:25-8. 1995
    ..This interhemispheric information transfer may represent a neurophysiological substrate of somatosensory fusion between the hands...
  54. doi request reprint [Early deep brain stimulation for Parkinson's disease]
    A Schnitzler
    Zentrum für Bewegungsstörungen und Neuromodulation der Neurologischen Klinik, Institut für Klinische Neurowissenschaften und Medizinische Psychologie, Universitätsklinikum der Heinrich Heine Universität Düsseldorf, Dusseldorf
    Fortschr Neurol Psychiatr 78:S37-40. 2010
    ....
  55. ncbi request reprint [Cortical representation of pain]
    M Ploner
    Neurologische Klinik, Heinrich Heine Universitat, Dusseldorf
    Nervenarzt 75:962-9. 2004
    ..Furthermore, first pain appears to be particularly related to activation of S1 whereas second pain is closely related to ACC activation...
  56. ncbi request reprint Enlargement of a chronic aseptic lumbar epidural abscess by intraspinal injections--a rare cause of progressive paraparesis
    M Sabel
    Department of Neurosurgery, Heinrich Heine University, Dusseldorf
    Zentralbl Neurochir 61:111-4. 2000
    ..Though we present a very rare cause of such complications, a careful monitoring of the neurological status of the patient is necessary as well as the early application of MR imaging in the case of deterioration...
  57. pmc Inter- versus intramodal integration in sensorimotor synchronization: a combined behavioral and magnetoencephalographic study
    Katharina Müller
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Exp Brain Res 185:309-18. 2008
    ..Present data shed new light on this question by demonstrating differences between modalities in the localization of the third source with similar temporal behavior...
  58. doi request reprint The effect of rTMS over left and right dorsolateral premotor cortex on movement timing of either hand
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Eur J Neurosci 27:757-64. 2008
    ..Additionally, they reveal a piece of evidence that the left dPMC affects the left hand not via a direct left dPMC-right M1 connection...
  59. doi request reprint Right hemisphere contributions to imitation tasks
    Katja Biermann-Ruben
    Department of Neurology, MEG Laboratory, Dusseldorf University Hospital, Moorenstrasse 5, 40225 Duesseldorf, Germany
    Eur J Neurosci 27:1843-55. 2008
    ....
  60. doi request reprint Evidence for anticipatory motor control within a cerebello-diencephalic-parietal network
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    J Cogn Neurosci 20:828-40. 2008
    ....
  61. ncbi request reprint Observing repetitive finger movements modulates response times of auditorily cued finger movements
    Katja Biermann-Ruben
    University Hospital Duesseldorf, Neurology, MEG Laboratory, Dusseldorf, Germany
    Brain Cogn 68:107-13. 2008
    ..These data suggest that the MNS is an "online" system; longstanding repetitive visual stimulation (Experiment 1) has no benefit in comparison to only one or two repetitions (Experiment 2)...
  62. doi request reprint Levodopa affects functional brain networks in Parkinsonian resting tremor
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 24:91-8. 2009
    ....
  63. ncbi request reprint Functional integration within the human pain system as revealed by Granger causality
    Markus Ploner
    Department of Neurology, Technische Universitat Munchen, Germany
    Hum Brain Mapp 30:4025-32. 2009
    ..These findings show how the analysis of functional integration complements traditional analyses of electrophysiological data and provides novel and behaviorally relevant information about the organization of the human pain system...
  64. doi request reprint Diagnostic and prognostic values of critical flicker frequency determination as new diagnostic tool for objective HE evaluation in patients undergoing TIPS implantation
    Gerald Kircheis
    Clinic for Gastroenterology, Hepatology and Infectiology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Eur J Gastroenterol Hepatol 21:1383-94. 2009
    ....
  65. pmc Differential effects of painful and non-painful stimulation on tactile processing in fibromyalgia syndrome and subjects with masochistic behaviour
    Bettina Pollok
    Institute of Clinical Neuroscience and Medical Psychology, University of Dusseldorf, Dusseldorf, Germany
    PLoS ONE 5:e15804. 2010
    ....
  66. ncbi request reprint Imitation in patients with Gilles de la Tourette syndrome--a behavioral study
    Melanie Jonas
    Department of Neurology, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Mov Disord 25:991-9. 2010
    ..Thus, movement stimuli may facilitate similar motor responses less but interfere more with different responses in these patients...
  67. doi request reprint Modality specific functional interaction in sensorimotor synchronization
    Bettina Pollok
    Department of Neurology, University Hospital, Universitatsstrasse 1, Duesseldorf, Germany
    Hum Brain Mapp 30:1783-90. 2009
    ..All in all the present data suggest that modality specific synchronization differences are associated with frequency and connectivity specific changes of functional interaction in distinct brain networks...
  68. doi request reprint Word deafness as a cortical auditory processing deficit: a case report with MEG
    Silke Jörgens
    Department of Neurology, University Hospital, Dusseldorf, Germany
    Neurocase 14:307-16. 2008
    ..We conclude that auditory processing is disturbed at long latency ranges following the N100, which may result in the clinical presentation of pure word deafness...
  69. ncbi request reprint Target consolidation under high temporal processing demands as revealed by MEG
    Klaus Kessler
    Department of Neurology, MEG Laboratory, Heinrich Heine University, Moorenstrasse 5, Dusseldorf 40225, Germany
    Neuroimage 26:1030-41. 2005
    ..Our data shed light on the mechanisms employed by the human brain for ensuring visual target processing under high temporal processing demands, which is hypothesized to occur at the expense of subsequently presented information...
  70. ncbi request reprint Pain processing is faster than tactile processing in the human brain
    Markus Ploner
    Department of Neurology, Heinrich Heine University, D 40225 Dusseldorf, Germany
    J Neurosci 26:10879-82. 2006
    ..Our observation shows how the cerebral organization of pain processing enhances motor responses to potentially harmful stimuli and thereby subserves the particular behavioral demands of pain...
  71. ncbi request reprint Oscillatory activity reflects the excitability of the human somatosensory system
    Markus Ploner
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Neuroimage 32:1231-6. 2006
    ....
  72. ncbi request reprint Critical flicker frequency for quantification of low-grade hepatic encephalopathy
    Gerald Kircheis
    Clinic for Gastroenterology, Hepatology and Infectiology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Hepatology 35:357-66. 2002
    ..In conclusion, CFF is a sensitive, simple, and reliable parameter for quantification of low-grade HE severity in cirrhotic patients and may be useful for the detection and monitoring of SHE...
  73. ncbi request reprint Pain suppresses spontaneous brain rhythms
    Markus Ploner
    Department of Neurology, Heinrich Heine University, 40225 Dusseldorf, Germany
    Cereb Cortex 16:537-40. 2006
    ..This global change in excitability may reflect the alerting function of pain which opens the gates for processing of and reacting to stimuli of existential relevance...
  74. ncbi request reprint How the brain controls repetitive finger movements
    Bettina Pollok
    Department of Neurology, MEG Laboratory, Heinrich Heine, University, Moorenstr 5, 40225 Duesseldorf, Germany
    J Physiol Paris 99:8-13. 2006
    ..This review focuses on studies investigating neuroelectric and neuromagnetic activity associated with simple repetitive synchronization tasks...
  75. ncbi request reprint Cortical dynamics and synchronization related to multiple target consolidation under rapid-serial-visual-presentation conditions
    Klaus Kessler
    Heinrich Heine University, Department of Neurology, MEG Laboratory, Moorenstrasse 5, Dusseldorf 40225, Germany
    J Physiol Paris 99:21-8. 2006
    ..Furthermore, enhanced vigilance of the system elicits systematically increased synchronization indices. A hypothetical framework is sketched out that aims at explaining limitations in multiple target consolidation under RSVP conditions...
  76. ncbi request reprint Right rolandic activation during speech perception in stutterers: a MEG study
    Katja Biermann-Ruben
    Department of Neurology, MEG Laboratory, University of Duesseldorf, Germany
    Neuroimage 25:793-801. 2005
    ..The present data suggest that activation in the left inferior frontal and right rolandic areas in stutterers differs from that in controls also during speech perception...
  77. ncbi request reprint Shrinkage of somatosensory hand area in subjects with upper extremity dysmelia revealed by magnetoencephalography
    M Cornelia Stoeckel
    Department of Neurology, University Hospital, Dusseldorf, Germany
    J Neurophysiol 93:813-8. 2005
    ....
  78. ncbi request reprint Cortical activations associated with auditorily paced finger tapping
    Bettina Pollok
    Max Planck Institute for Psychological Research, Munich, Germany
    Neuroreport 14:247-50. 2003
    ..Thus, activation in the primary somatosensory cortex most likely represents exclusively somatosensory feedback and no further cognitive processes...
  79. ncbi request reprint The role of the primary somatosensory cortex in an auditorily paced finger tapping task
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Exp Brain Res 156:111-7. 2004
    ....
  80. ncbi request reprint Asymmetry of interhemispheric interaction in left-handed subjects
    Bettina Pollok
    Department of Neurology, MEG Laboratory, Heinrich Heine University, Duesseldorf, Germany
    Exp Brain Res 175:268-75. 2006
    ..A specialization of the left premotor cortex either for superior motor control per se or for the execution of sequential tasks might account for these results...
  81. ncbi request reprint Intercerebellar coupling contributes to bimanual coordination
    Bettina Pollok
    Heinrich Heine University, Duesseldorf, Germany
    J Cogn Neurosci 19:704-19. 2007
    ....
  82. ncbi request reprint Anticipatory control of long-range phase synchronization
    Joachim Gross
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Eur J Neurosci 24:2057-60. 2006
    ..These observations are consistent with the hypothesis that long-range phase synchronization plays a critical functional role in humans' ability to effectively employ predictive heuristics...
  83. ncbi request reprint Coupling between cerebellar hemispheres: behavioural, anatomic, and functional data
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Cerebellum 5:212-9. 2006
    ..The present article reviews behavioural, functional, and anatomic data to shed light on possible interactions between both cerebellar hemispheres during the execution of timed motor behaviour...
  84. ncbi request reprint Changes of motor-cortical oscillations associated with motor learning
    B Pollok
    Heinrich Heine University Duesseldorf, Medical Faculty, Institute of Clinical Neuroscience and Medical Psychology, D 40225 Duesseldorf, Germany Electronic address
    Neuroscience 275:47-53. 2014
    ....
  85. ncbi request reprint Local Lyapunov exponents detect epileptic zones in spike-less interictal MEG recordings
    Z J Kowalik
    Department of Neurology, Heinrich Heine University Dusseldorf, Moorenstrasse 5, D 40225, Dusseldorf, Germany
    Clin Neurophysiol 112:60-7. 2001
    ..We explored whether such a multistability is reflected also in the dynamical characteristics of the interictal signal...
  86. ncbi request reprint Perilesional pathological oscillatory activity in the magnetoencephalogram of patients with cortical brain lesions
    Markus Butz
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Neurosci Lett 355:93-6. 2004
    ..Our results indicate that perilesional delta activity is common after ischemic cortical stroke. However, the functional significance remains to be elucidated...
  87. pmc Gamma oscillations in human primary somatosensory cortex reflect pain perception
    Joachim Gross
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    PLoS Biol 5:e133. 2007
    ..Our findings support the hypothesis that gamma oscillations are related to the internal representation of behaviorally relevant stimuli that should receive preferred processing...
  88. ncbi request reprint Reduced inhibition within primary motor cortex in patients with poststroke focal motor seizures
    Kirn R Kessler
    Department of Neurology, University of Frankfurt, Frankfurt Main, Germany
    Neurology 59:1028-33. 2002
    ....
  89. pmc Cortical representation of first and second pain sensation in humans
    Markus Ploner
    Department of Neurology, Heinrich Heine University, 40225 Dusseldorf, Germany
    Proc Natl Acad Sci U S A 99:12444-8. 2002
    ..First pain signals threat and provides precise sensory information for an immediate withdrawal, whereas second pain attracts longer-lasting attention and motivates behavioral responses to limit further injury and optimize recovery...
  90. ncbi request reprint Image-to-sound conversion: experience-induced plasticity in auditory cortex of blindfolded adults
    Bettina Pollok
    Department of Neurology, Heinrich Heine University, Moorenstr 5, 40225 Duesseldorf, Germany
    Exp Brain Res 167:287-91. 2005
    ..The fact that changes occurred only in response to "natural sounds" probably reflects the increased behavioural relevance of this category evident only for blindfolded subjects using the substitution device...
  91. ncbi request reprint Cortical representation of venous nociception in humans
    Markus Ploner
    Department of Neurology, Heinrich Heine University, 40225 Dusseldorf, Germany
    J Neurophysiol 88:300-5. 2002
    ..Thus the cortical representation of nociceptive processing from tissues of mesodermal and ectodermal origin appears to be similar...
  92. ncbi request reprint Early-onset multisystem degeneration with central motor, autonomic and optic nerve disturbances: unusual Riley-Day syndrome or new clinical entity?
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    J Neurol Sci 154:205-8. 1998
    ..We consider this syndrome a slowly progressive multisystemic degeneration with two unusual hitherto unreported features: the combination of affected systems (autonomic and motor systems, optic nerves), and the early onset...
  93. ncbi request reprint Observation of a finger or an object movement primes imitative responses differentially
    M Jonas
    Department of Neurology, University Medical Center Hamburg Eppendorf, Martinistr 52, 20246, Hamburg, Germany
    Exp Brain Res 177:255-65. 2007
    ..Thus, S1 immediately elicits an imitative response tendency. As an overt imitation of S1 is inadequate in the present setting, the response is inhibited which, in turn, modulates congruency effects...
  94. ncbi request reprint Transcallosally mediated inhibition of interneurons within human primary motor cortex
    A Schnitzler
    Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
    Exp Brain Res 112:381-91. 1996
    ....
  95. doi request reprint Structural changes in the somatosensory system correlate with tic severity in Gilles de la Tourette syndrome
    Gotz Thomalla
    Department of Neurology, University Medial Center Hamburg Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    Brain 132:765-77. 2009
    ..The negative correlation between higher regional FA values and fewer tics suggests that these alterations of white matter microstructure represent adaptive reorganization of somatosensory processing in GTS...
  96. ncbi request reprint Differential effects of levodopa and subthalamic nucleus deep brain stimulation on bradykinesia in Parkinson's disease
    Lars Timmermann
    Department of Neurology, University of Cologne, Cologne, Germany
    Mov Disord 23:218-27. 2008
    ..This study demonstrates a better effect of levodopa on distal finger movements and STN-DBS on proximal diadochokinesia. Furthermore, a complementary effect of both therapies on brain areas involved in bradykinesia can be assumed...
  97. ncbi request reprint Postural tremor in Wilson's disease: a magnetoencephalographic study
    Martin Südmeyer
    Department of Neurology, Heinrich Heine University, Dusseldorf, Germany
    Mov Disord 19:1476-82. 2004
    ..Taken together, our results indicate that postural tremor in WD is mediated through a pathological oscillatory drive from the primary motor cortex...
  98. ncbi request reprint Frequency-dependent reciprocal modulation of verbal fluency and motor functions in subthalamic deep brain stimulation
    Lars Wojtecki
    Department of Neurology, Heinrich Heine University, Moorenstrasse 5, 40225 Dusseldorf, Germany
    Arch Neurol 63:1273-6. 2006
    ..In contrast, low-frequency DBS leads to deterioration of motor functions. It is not known whether low-frequency STN DBS also has an effect on frontal functions...
  99. ncbi request reprint Hepatic encephalopathy and fitness to drive
    Gerald Kircheis
    Department of Gastroenterology, Hepatology and Infectiology, Heinrich Heine University, Dusseldorf, Germany
    Gastroenterology 137:1706-15.e1-9. 2009
    ..Low-grade hepatic encephalopathy (HE) may impair fitness to drive. Driving deficits have not yet been characterized, and their relation to psychometric test results is unclear...
  100. pmc Deep brain stimulation in Parkinson's disease
    S J Groiss
    Department of Neurology, Center for Movement Disorders and Neuromodulation, Heinrich Heine University of Dusseldorf, Germany, Institute of Clinical Neuroscience and Medical Psychology, Heinrich Heine University of Dusseldorf, Germany
    Ther Adv Neurol Disord 2:20-8. 2009
    ..It is presently investigated whether the optimal timing for implantation may be at an earlier disease-stage to prevent psychosocial decline and to maintain quality of life for a longer period of time...
  101. doi request reprint Risk factors for executive dysfunction after subthalamic nucleus stimulation in Parkinson's disease
    Christine Daniels
    Department of Neurology, Christian Albrechts University, Kiel, Germany
    Mov Disord 25:1583-9. 2010
    ....