P Schadewaldt

Summary

Affiliation: Heinrich Heine University
Country: Germany

Publications

  1. ncbi Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS)
    P Schadewaldt
    Diabetes Forschungsinstitut, Klinische Biochemie Auf m Hennekamp 65, Dusseldorf, Germany
    Clin Chem 43:518-22. 1997
  2. ncbi Biochemical monitoring of pregnancy and breast feeding in five patients with classical galactosaemia--and review of the literature
    Peter Schadewaldt
    German Diabetic Centre, Department of Clinical Biochemistry and Pathobiochemistry, UKD, University of Dusseldorf, Dusseldorf, Germany
    Eur J Pediatr 168:721-9. 2009
  3. ncbi Indirect calorimetry in humans: a postcalorimetric evaluation procedure for correction of metabolic monitor variability
    Peter Schadewaldt
    Institutes of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Dusseldorf, Dusseldorf, Germany
    Am J Clin Nutr 97:763-73. 2013
  4. ncbi Longitudinal assessment of intellectual achievement in patients with classical galactosemia
    Peter Schadewaldt
    Deutsches Diabetes Zentrum, Abteilung Klinische Biochemie und Pathobiochemie, Auf m Hennekamp 65, D 40225 Dusseldorf, Germany
    Pediatrics 125:e374-81. 2010
  5. ncbi Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Metabolic Unit, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 801:249-55. 2004
  6. ncbi Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Mol Genet Metab 81:31-44. 2004
  7. ncbi Stable-isotope dilution analysis of galactose metabolites in human erythrocytes
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Rapid Commun Mass Spectrom 17:2833-8. 2003
  8. ncbi Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects
    P Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum Dusseldorf, Dusseldorf, Germany
    J Inherit Metab Dis 26:459-79. 2003
  9. ncbi Whole-body L-leucine oxidation in patients with variant form of maple syrup urine disease
    P Schadewaldt
    Deutsches Diabetes Forschungsinstitut, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Pediatr Res 49:627-35. 2001
  10. ncbi Analysis of concentration and (13)C enrichment of D-galactose in human plasma
    P Schadewaldt
    Deutsches Diabetes Forschungsinstitut an der Heinrich Heine Universität, Auf m Hennekamp 65, D 40225 Dusseldorf, Germany
    Clin Chem 46:612-9. 2000

Detail Information

Publications17

  1. ncbi Application of isotope-selective nondispersive infrared spectrometry (IRIS) for evaluation of [13C]octanoic acid gastric-emptying breath tests: comparison with isotope ratio-mass spectrometry (IRMS)
    P Schadewaldt
    Diabetes Forschungsinstitut, Klinische Biochemie Auf m Hennekamp 65, Dusseldorf, Germany
    Clin Chem 43:518-22. 1997
    ..99x + 4.06, Sy[symbol: see text]x = +/- 6.3; tlag, breath: y = 0.97x + 0.96, Sy[symbol: see text]x = +/-3.4; GEC: y = 0.97x - 0.01, Sy[symbol: see text]x = +/-0.09)...
  2. ncbi Biochemical monitoring of pregnancy and breast feeding in five patients with classical galactosaemia--and review of the literature
    Peter Schadewaldt
    German Diabetic Centre, Department of Clinical Biochemistry and Pathobiochemistry, UKD, University of Dusseldorf, Dusseldorf, Germany
    Eur J Pediatr 168:721-9. 2009
    ..In conclusion, a specific metabolic monitoring is apparently not required in pregnant galactosemic women, and breast feeding of the nongalactosemic offspring can be recommended...
  3. ncbi Indirect calorimetry in humans: a postcalorimetric evaluation procedure for correction of metabolic monitor variability
    Peter Schadewaldt
    Institutes of Clinical Biochemistry and Pathobiochemistry, German Diabetes Center, Dusseldorf, Dusseldorf, Germany
    Am J Clin Nutr 97:763-73. 2013
    ..Indirect calorimetry (IC) with metabolic monitors is widely used for noninvasive assessment of energy expenditure and macronutrient oxidation in health and disease...
  4. ncbi Longitudinal assessment of intellectual achievement in patients with classical galactosemia
    Peter Schadewaldt
    Deutsches Diabetes Zentrum, Abteilung Klinische Biochemie und Pathobiochemie, Auf m Hennekamp 65, D 40225 Dusseldorf, Germany
    Pediatrics 125:e374-81. 2010
    ..To conduct a longitudinal assessment of long-term cognitive outcome in patients with classical galactosemia...
  5. ncbi Galactonate determination in urine by stable isotope dilution gas chromatography-mass spectrometry
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Metabolic Unit, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    J Chromatogr B Analyt Technol Biomed Life Sci 801:249-55. 2004
    ..The procedure was applied to study the variability of D-galactonate excretion in healthy subjects and galactosemic patients and to monitor the D-galactonate-D-galactitol ratio in human urine...
  6. ncbi Age dependence of endogenous galactose formation in Q188R homozygous galactosemic patients
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Mol Genet Metab 81:31-44. 2004
    ..The present findings can explain the persistently elevated galactose-1-phosphate levels in erythrocytes-and its age dependence-in galactosemic patients even when under strict dietary treatment...
  7. ncbi Stable-isotope dilution analysis of galactose metabolites in human erythrocytes
    Peter Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum, Heinrich Heine Universitat Dusseldorf, Moorenstrasse 5, D 40225 Dusseldorf, Germany
    Rapid Commun Mass Spectrom 17:2833-8. 2003
    ..20 mol/L(RBC), respectively. The procedure allowed simultaneous galactitol analysis and proved to be useful to trace incorporation of (13)C-label into erythrocyte galactose metabolites in a D-[1-(13)C]galactose in vivo turnover study...
  8. ncbi Renal excretion of galactose and galactitol in patients with classical galactosaemia, obligate heterozygous parents and healthy subjects
    P Schadewaldt
    Klinik fur Allgemeine Padiatrie, Universitatsklinikum Dusseldorf, Dusseldorf, Germany
    J Inherit Metab Dis 26:459-79. 2003
    ....
  9. ncbi Whole-body L-leucine oxidation in patients with variant form of maple syrup urine disease
    P Schadewaldt
    Deutsches Diabetes Forschungsinstitut, Heinrich Heine Universitat Dusseldorf, Dusseldorf, Germany
    Pediatr Res 49:627-35. 2001
    ..Possible mechanisms are considered that might contribute to a comparatively high residual in vivo L-leucine oxidation in (mild) variant maple syrup urine disease...
  10. ncbi Analysis of concentration and (13)C enrichment of D-galactose in human plasma
    P Schadewaldt
    Deutsches Diabetes Forschungsinstitut an der Heinrich Heine Universität, Auf m Hennekamp 65, D 40225 Dusseldorf, Germany
    Clin Chem 46:612-9. 2000
    ..A stable-isotope dilution method for the sensitive determination of D-galactose in human plasma was established...
  11. ncbi Renal clearance of branched-chain L-amino and 2-oxo acids in maple syrup urine disease
    P Schadewaldt
    Diabetes Forschungsinstitut an der Heinrich Heine Universität, Dusseldorf, Germany
    J Inherit Metab Dis 22:706-22. 1999
    ..The renal excretion of BCOA, however, to some extent counteracts increases in BCAA concentrations and thus contributes to the lowering of total BCAA pools in MSUD...
  12. ncbi Significance of L-alloisoleucine in plasma for diagnosis of maple syrup urine disease
    P Schadewaldt
    Diabetes Forschungsinstitut and Kinderklinik, Heinrich Heine Universitat, D 40225 Dusseldorf, Germany
    Clin Chem 45:1734-40. 1999
    ..The significance of plasma L-alloisoleucine, which is derived from L-isoleucine in vivo, for diagnosis of maple syrup urine disease (MSUD) was examined...
  13. ncbi Description of the mutations in 15 subjects with variant forms of maple syrup urine disease
    N Flaschker
    Department of General Paediatrics, University Children s Hospital, Heinrich Heine University, Dusseldorf, Germany
    J Inherit Metab Dis 30:903-9. 2007
    ..In maple syrup urine disease (MSUD), disease-causing mutations can affect the BCKDHA, BCKDHB or DBT genes encoding for the E1 alpha, E1 beta and E2 subunits of the multienzyme branched-chain 2-keto acid dehydrogenase (BCKD) complex...
  14. ncbi Variant maple syrup urine disease (MSUD)--the entire spectrum
    E Simon
    Department of General Paediatrics, University Children s Hospital, Heinrich Heine University, Moorenstr 5, D 40225, Dusseldorf, Germany
    J Inherit Metab Dis 29:716-24. 2006
    ..Aim: Up to now variant cases have mostly been published as individual case reports; the aim of this study was to give a comparative description of 16 individuals (aged 6-30 years) with different forms of variant MSUD...
  15. ncbi Urinary excretion of the nitrotyrosine metabolite 3-nitro-4-hydroxyphenylacetic acid in preterm and term infants
    Thomas Hoehn
    Neonatology and Paediatric Intensive Care Medicine, Department of General Paediatrics, Heinrich Heine University, Dusseldorf, Germany
    Neonatology 93:73-6. 2008
    ..Nitrative stress is predominantly caused following synthesis of peroxynitrite. Particularly preterm infants with immature defense mechanisms against free radical injury appear at risk...
  16. ncbi Neonatal screening, clinical features and genetic testing for galactosemia
    Marco Zaffanello
    Genet Med 7:211-2. 2005
  17. ncbi A woman with untreated galactosaemia
    Philip J Lee
    The Charles Dent Metabolic Unit, The National Hospital for Neurology and Neurosurgery, Queen Square, WC1N 3BG, London, United Kingdom
    Lancet 362:446. 2003